"Doxepin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
| Descriptor ID |
D004316
|
| MeSH Number(s) |
D02.355.291.852.500 D03.633.300.382.393
|
| Concept/Terms |
Doxepin Hydrochloride- Doxepin Hydrochloride
- Hydrochloride, Doxepin
- Doxepin Hydrochloride, Cis-Trans Isomer Mixture (approximately 1:5)
|
Below are MeSH descriptors whose meaning is more general than "Doxepin".
Below are MeSH descriptors whose meaning is more specific than "Doxepin".
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Below are the most recent publications written about "Doxepin" by people in Profiles.
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Banerjee SP, Kung LS, Riggi SJ, Chanda SK. Development of beta-adrenergic receptor subsensitivity by antidepressants. Nature. 1977 Aug 04; 268(5619):455-6.