"Dihydroxyphenylalanine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
| Descriptor ID |
D004295
|
| MeSH Number(s) |
D02.092.311.200 D12.125.072.050.685.400 D12.125.072.050.875.130
|
| Concept/Terms |
Dihydroxyphenylalanine- Dihydroxyphenylalanine
- beta-Hydroxytyrosine
- beta Hydroxytyrosine
- 3-Hydroxy-DL-tyrosine
- 3 Hydroxy DL tyrosine
- 3,4-Dihydroxyphenylalanine
- 3,4 Dihydroxyphenylalanine
- Dopa
|
Below are MeSH descriptors whose meaning is more general than "Dihydroxyphenylalanine".
Below are MeSH descriptors whose meaning is more specific than "Dihydroxyphenylalanine".
This graph shows the total number of publications written about "Dihydroxyphenylalanine" by people in this website by year, and whether "Dihydroxyphenylalanine" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Dihydroxyphenylalanine" by people in Profiles.
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Cherukula K, Nurunnabi M, Jeong YY, Lee YK, Park IK. A targeted graphene nanoplatform carrying histamine dihydrochloride for effective inhibition of leukemia-induced immunosuppression. J Biomater Sci Polym Ed. 2018 May - Jun; 29(7-9):734-749.
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Yuan B, Wu H, Sanders T, McCullum C, Zheng Y, Tchounwou PB, Liu YM. Chiral capillary electrophoresis-mass spectrometry of 3,4-dihydroxyphenylalanine: evidence for its enantioselective metabolism in PC-12 nerve cells. Anal Biochem. 2011 Sep 15; 416(2):191-5.
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Tian Y, Eaton MJ, Goudreau JL, Lookingland KJ, Moore KE. Neurochemical evidence that 5-hydroxytryptaminergic neurons tonically inhibit noradrenergic neurons terminating in the hypothalamus. Brain Res. 1993 Apr 02; 607(1-2):215-21.
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Lundell MJ, Hirsh J. The zfh-2 gene product is a potential regulator of neuron-specific dopa decarboxylase gene expression in Drosophila. Dev Biol. 1992 Nov; 154(1):84-94.
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Manzanares J, Toney TW, Tian Y, Eaton MJ, Moore KE, Lookingland KJ. Sexual differences in the activity of periventricular-hypophysial dopaminergic neurons in rats. Life Sci. 1992; 51(13):995-1001.
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Van Woert MH, Mueller PS, Ambani LM, Rathey U. Abnormal insulin secretion in Parkinson's disease before and during L-dihydroxyphenylalanine (L-dopa) therapy. J Endocrinol. 1973 Dec; 59(3):523-34.
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Van Woert MH, Mueller PS. Glucose, insulin, and free fatty acid metabolism in Parkinson's disease treated with levodopa. Clin Pharmacol Ther. 1971 Mar-Apr; 12(2):360-7.