Reinvestigation of clopidogrel bioactivation unveils new cytochrome P450-catalyzed thioester cleavage mechanism.

Zhu Y, Zhou J, Romero EL. Reinvestigation of clopidogrel bioactivation unveils new cytochrome P450-catalyzed thioester cleavage mechanism. Bioorg Med Chem Lett. 2022 09 15; 72:128872.

View in: PubMed

subject areas

Catalysis
Cytochrome P-450 Enzyme System
Microsomes, Liver
Oxidation-Reduction
Sulfenic Acids

authors with profiles

Yaoqiu Zhu

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