Resveratrol blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells.

Estrov Z, Shishodia S, Faderl S, Harris D, Van Q, Kantarjian HM, Talpaz M, Aggarwal BB. Resveratrol blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells. Blood. 2003 Aug 01; 102(3):987-95.

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subject areas

Acute Disease
Aged
Antineoplastic Agents, Phytogenic
Apoptosis
Bone Marrow
Cell Division
Female
Humans
Interleukin-1
Leukemia, Myeloid
Male
Middle Aged
NF-kappa B
S Phase
Stilbenes
Tumor Cells, Cultured

authors with profiles

Shishir Shishodia

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