Mice lacking selenoprotein P and selenocysteine lyase exhibit severe neurological dysfunction, neurodegeneration, and audiogenic seizures.
Byrns CN, Pitts MW, Gilman CA, Hashimoto AC, Berry MJ. Mice lacking selenoprotein P and selenocysteine lyase exhibit severe neurological dysfunction, neurodegeneration, and audiogenic seizures. J Biol Chem. 2014 Apr 04; 289(14):9662-74.