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Ihsan Salloum

TitleProfessor of Medicine
Faculty RankProfessor
InstitutionUniversity of Texas Rio Grande Valley
Department NBHISU Neuroscience
Address2102 Treasure Hills Boulevard
Harlingen TX 78550
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    R29AA010523     (SALLOUM, IHSAN M)Mar 1, 1996 - Feb 28, 2002
    NIH
    EFFICACY OF VALPROATE MAINTENANCE IN BIPOLAR ALCOHOLICS
    Role: Principal Investigator
    R01AA011929     (SALLOUM, IHSAN M)Mar 1, 2000 - Feb 28, 2006
    NIH
    COMBINED PHARMACOTHERAPY IN DEPRESSED ALCOHOLICS
    Role: Principal Investigator
    R21AA014396     (SALLOUM, IHSAN M)Sep 1, 2003 - Jul 31, 2007
    NIH
    Recovery Adherence Therapy for Bipolar Alcoholics
    Role: Principal Investigator
    R01DA019992     (SALLOUM, IHSAN M)Sep 5, 2005 - Mar 31, 2014
    NIH
    Valproate Efficacy in Cocaine-Bipolar Comorbidity
    Role: Principal Investigator
    R01AA015385     (SALLOUM, IHSAN M)Mar 1, 2006 - Apr 30, 2013
    NIH
    Optimizing Pharmacotherapy for Bipolar Alcoholics
    Role: Principal Investigator
    R01AA023540     (BROWN, E SHERWOOD)Sep 1, 2015 - May 31, 2021
    NIH
    Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders
    Role: Co-Principal Investigator
    R01AA024933     (SALLOUM, IHSAN M)Sep 1, 2017 - Jun 30, 2022
    NIH
    Stem Cell Therapy, Inflammation and Treatement Response in Alcholoism-Depression Comobidity
    Role: Principal Investigator
    R13DA056203     (SALLOUM, IHSAN M)Jul 1, 2022 - Jun 30, 2024
    NIH
    UTRGV International Conference on Health Disparities: Treatment and Recovery from Opioid and Alcohol Use Disorders and Related Comorbidities (ICHD-Recover)
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Han A, Almeida L, Anand N, Salloum IM, Kanaan S, Gadad BS, Daher JPL. Exploring neuropsychiatric manifestations of vitamin B complex deficiencies. Front Psychiatry. 2025; 16:1569826. PMID: 40904570.
      Citations:    
    2. Francis AN, Salloum IM. High-resolution mapping of alcohol-related brain connectivity in adults using 7T fMRI and multivoxel pattern classification. Psychiatry Res Neuroimaging. 2025 Sep; 352:112046. PMID: 40816048.
      Citations:    Fields:    Translation:Humans
    3. Ware OD, Cano MT, Dalal Safa M, Garza N, Martinez S, Salloum I. Availability of substance use disorder treatment in Spanish: Associations with state-level proportions of Spanish speakers and treatment facility characteristics in the United States. Am J Addict. 2024 07; 33(4):400-408. PMID: 38264804.
      Citations: 1     Fields:    Translation:Humans
    4. Blokhin IO, Martinez-Garza DM, Patel D, Douaihy AB, Salloum IM. Editorial: Genome-wide molecular mechanisms of substance use disorders. Front Psychiatry. 2023; 14:1356103. PMID: 38260789.
      Citations:    
    5. Haddadi S, Murthi M, Salloum I, Mirsaeidi MS. COVID-19: Risk of alcohol abuse and psychiatric disorders. Respir Med Case Rep. 2020; 31:101222. PMID: 32953449.
      Citations:    
    6. Miller ML, Cornelius JR, Kirisci L, Douaihy A, Salloum IM. Depressive and Anxiety Symptoms Predict Obsessive and Compulsive Cravings among Depressed Alcoholics. Addict Disord Their Treat. 2020 Dec; 19(4):228-233. PMID: 38516416.
      Citations:    
    7. Kwako LE, Patterson J, Salloum IM, Trim RS. Alcohol Use Disorder and Co-Occurring Mental Health Conditions. Alcohol Res. 2019; 40(1). PMID: 31942280.
      Citations: 7     Fields:    Translation:Humans
    8. Falk DE, Ryan ML, Fertig JB, Devine EG, Cruz R, Brown ES, Burns H, Salloum IM, Newport DJ, Mendelson J, Galloway G, Kampman K, Brooks C, Green AI, Brunette MF, Rosenthal RN, Dunn KE, Strain EC, Ray L, Shoptaw S, Ait-Daoud Tiouririne N, Gunderson EW, Ransom J, Scott C, Leggio L, Caras S, Mason BJ, Litten RZ. Gabapentin Enacarbil Extended-Release for Alcohol Use Disorder: A Randomized, Double-Blind, Placebo-Controlled, Multisite Trial Assessing Efficacy and Safety. Alcohol Clin Exp Res. 2019 01; 43(1):158-169. PMID: 30403402.
      Citations: 46     Fields:    Translation:Humans
    9. Sinha A, Shariq A, Said K, Sharma A, Jeffrey Newport D, Salloum IM. Medical Comorbidities in Bipolar Disorder. Curr Psychiatry Rep. 2018 05 07; 20(5):36. PMID: 29732528.
      Citations: 21     Fields:    Translation:Humans
    10. Cisse A, Giles C, Salloum IM. Yoga in the Yard. Psychiatr Serv. 2017 09 01; 68(9):980. PMID: 28862098.
      Citations:    Fields:    Translation:Humans
    11. Salloum IM, Brown ES. Management of comorbid bipolar disorder and substance use disorders. Am J Drug Alcohol Abuse. 2017 07; 43(4):366-376. PMID: 28301219.
      Citations: 31     Fields:    Translation:Humans
    12. Balsamo DN, Douaihy A, Cornelius JR, Daley DC, Kirisci L, Hyman SM, Salloum IM. Differential Impact of Depressive and Manic Mood States on Alcohol Craving in Comorbid Bipolar Alcoholism: Preliminary Findings. Addict Disord Their Treat. 2016 Sep; 15(3):107-110. PMID: 27594809.
      Citations:    
    13. Mar?n-Navarrete R, Medina-Mora ME, Horigian VE, Salloum IM, Villalobos-Gallegos L, Fern?ndez-Mondrag?n J. Co-Occurring Disorders: A Challenge for Mexican Community-Based Residential Care Facilities for Substance Use. J Dual Diagn. 2016 Jul-Dec; 12(3-4):261-270. PMID: 27494051.
      Citations: 11     Fields:    Translation:Humans
    14. Cornelius JR, Chung T, Douaihy AB, Kirisci L, Glance J, Kmiec J, FitzGerald D, Wesesky MA, Salloum I. Mirtazapine in comorbid major depression and an alcohol use disorder: A double-blind placebo-controlled pilot trial. Psychiatry Res. 2016 Aug 30; 242:326-330. PMID: 27327217.
      Citations: 6     Fields:    Translation:Humans
    15. Garcia AN, Salloum IM. Polysomnographic sleep disturbances in nicotine, caffeine, alcohol, cocaine, opioid, and cannabis use: A focused review. Am J Addict. 2015 Oct; 24(7):590-8. PMID: 26346395.
      Citations: 75     Fields:    Translation:HumansAnimals
    16. Cornelius JR, Douaihy AB, Clark DB, Daley DC, Chung TA, Wesesky MA, Wood DS, Salloum I. Mirtazapine in Comorbid Major Depression and Alcohol Use Disorder: A Long-Term Follow-Up Study. J Addict Behav Ther Rehabil. 2013 Aug 24; 3(1). PMID: 25374892.
      Citations:    
    17. Cornelius JR, Aizenstein HJ, Chung TA, Douaihy A, Hayes J, Daley D, Salloum IM. Paradoxical Decrease in Striatal Activation on an fMRI Reward Task Following Treatment in Youth with Co-morbid Cannabis Dependence/Major Depression. Adv Psychol Res. 2013; 93:123-130. PMID: 25904826.
      Citations:    
    18. Cloninger CR, Salloum IM, Mezzich JE. The dynamic origins of positive health and wellbeing. Int J Pers Cent Med. 2012 Jun; 2(2):179-187. PMID: 26140189.
      Citations:    
    19. Cornelius JR, Haas GL, Appelt CJ, Walker JD, Fox LJ, Kasckow JW, Luther JF, Salloum IM. Suicidal Ideation Associated with PCL Checklist-Ascertained PTSD among Veterans Treated for Substance Abuse. Int J Med Biol Front. 2012; 18(11):783-794. PMID: 25382964.
      Citations:    
    20. Cornelius JR, Salloum IM, Ferrell R, Douaihy AB, Hayes J, Kirisci L, Horner M, Daley DC. TREATMENT TRIAL AND LONG-TERM FOLLOW-UP EVALUATION AMONG COMORBID YOUTH WITH MAJOR DEPRESSION AND A CANNABIS USE DISORDER. Int J Med Biol Front. 2012; 18(6):399-411. PMID: 25328373.
      Citations:    
    21. Johnson SL, Murray G, Fredrickson B, Youngstrom EA, Hinshaw S, Bass JM, Deckersbach T, Schooler J, Salloum I. Creativity and bipolar disorder: touched by fire or burning with questions? Clin Psychol Rev. 2012 Feb; 32(1):1-12. PMID: 22088366.
      Citations: 25     Fields:    Translation:Humans
    22. Cornelius JR, Douaihy A, Bukstein OG, Daley DC, Wood SD, Kelly TM, Salloum IM. Evaluation of cognitive behavioral therapy/motivational enhancement therapy (CBT/MET) in a treatment trial of comorbid MDD/AUD adolescents. Addict Behav. 2011 Aug; 36(8):843-8. PMID: 21530092.
      Citations: 27     Fields:    Translation:Humans
    23. Balon R, Guerra E, Meador-Woodruff JH, Oquendo MA, Salloum IM, Casiano DE, Nemeroff CB. Innovative approach to research training: research colloquium for junior investigators. Acad Psychiatry. 2011 Jan-Feb; 35(1):11-4. PMID: 21209401.
      Citations: 8     Fields:    Translation:Humans
    24. Mezzich JE, Snaedal J, van Weel C, Botbol M, Salloum I. Introduction to person-centred medicine: from concepts to practice. J Eval Clin Pract. 2011 Apr; 17(2):330-2. PMID: 21143349.
      Citations: 15     Fields:    Translation:Humans
    25. Salloum IM, Mezzich JE. Outlining the bases of person-centred integrative diagnosis. J Eval Clin Pract. 2011 Apr; 17(2):354-6. PMID: 21114718.
      Citations: 4     Fields:    Translation:Humans
    26. Mezzich JE, Salloum IM, Cloninger CR, Salvador-Carulla L, Kirmayer LJ, Banzato CE, Wallcraft J, Botbol M. Person-centred integrative diagnosis: conceptual bases and structural model. Can J Psychiatry. 2010 Nov; 55(11):701-8. PMID: 21070697.
      Citations: 27     Fields:    Translation:Humans
    27. Maremmani I, Pacini M, Lamanna F, Pani PP, Perugi G, Deltito J, Salloum IM, Akiskal H. Mood stabilizers in the treatment of substance use disorders. CNS Spectr. 2010 Feb; 15(2):95-109. PMID: 20414155.
      Citations: 7     Fields:    Translation:Humans
    28. Salloum IM, Mezzich JE. Person-centered diagnosis. Int J Integr Care. 2010 Jan 29; 10 Suppl:e027. PMID: 20228924.
      Citations:    
    29. Ostacher MJ, Perlis RH, Nierenberg AA, Calabrese J, Stange JP, Salloum I, Weiss RD, Sachs GS. Impact of substance use disorders on recovery from episodes of depression in bipolar disorder patients: prospective data from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD). Am J Psychiatry. 2010 Mar; 167(3):289-97. PMID: 20008948.
      Citations: 37     Fields:    Translation:HumansPHPublic Health
    30. Anderson AL, Reid MS, Li SH, Holmes T, Shemanski L, Slee A, Smith EV, Kahn R, Chiang N, Vocci F, Ciraulo D, Dackis C, Roache JD, Salloum IM, Somoza E, Urschel HC, Elkashef AM. Modafinil for the treatment of cocaine dependence. Drug Alcohol Depend. 2009 Sep 01; 104(1-2):133-9. PMID: 19560290.
      Citations: 121     Fields:    Translation:Humans
    31. Mezzich JE, Salloum IM. Clinical complexity and person-centered integrative diagnosis. World Psychiatry. 2008 Feb; 7(1):1-2. PMID: 18458769.
      Citations:    
    32. Copeland LA, Zeber JE, Salloum IM, Pincus HA, Fine MJ, Kilbourne AM. Treatment adherence and illness insight in veterans with bipolar disorder. J Nerv Ment Dis. 2008 Jan; 196(1):16-21. PMID: 18195637.
      Citations: 20     Fields:    Translation:Humans
    33. Mezzich JE, Salloum IM. Towards innovative international classification and diagnostic systems: ICD-11 and person-centered integrative diagnosis. Acta Psychiatr Scand. 2007 Jul; 116(1):1-5. PMID: 17559594.
      Citations: 9     Fields:    Translation:Humans
    34. Frye MA, Salloum IM. Bipolar disorder and comorbid alcoholism: prevalence rate and treatment considerations. Bipolar Disord. 2006 Dec; 8(6):677-85. PMID: 17156154.
      Citations: 40     Fields:    Translation:Humans
    35. Salloum IM, Douaihy A, Cornelius JR, Kirisci L, Kelly TM, Hayes J. Divalproex utility in bipolar disorder with co-occurring cocaine dependence: a pilot study. Addict Behav. 2007 Feb; 32(2):410-5. PMID: 16814474.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    36. Kilbourne AM, Salloum I, Dausey D, Cornelius JR, Conigliaro J, Xu X, Pincus HA. Quality of care for substance use disorders in patients with serious mental illness. J Subst Abuse Treat. 2006 Jan; 30(1):73-7. PMID: 16377454.
      Citations: 3     Fields:    Translation:Humans
    37. Douaihy AB, Stowell KR, Bui T, Daley D, Salloum I. HIV/AIDS and homelessness, Part 2: treatment issues. AIDS Read. 2005 Nov; 15(11):604-6, 611-3, 618. PMID: 16329182.
      Citations: 3     Fields:    Translation:Humans
    38. Douaihy AB, Stowell KR, Bui T, Daley D, Salloum I. HIV/AIDS and homelessness, Part 1: background and barriers to care. AIDS Read. 2005 Oct; 15(10):516-20, 527. PMID: 16265767.
      Citations: 7     Fields:    Translation:Humans
    39. Cornelius JR, Clark DB, Bukstein OG, Birmaher B, Salloum IM, Brown SA. Acute phase and five-year follow-up study of fluoxetine in adolescents with major depression and a comorbid substance use disorder: a review. Addict Behav. 2005 Oct; 30(9):1824-33. PMID: 16102905.
      Citations: 21     Fields:    Translation:Humans
    40. Salloum IM, Cornelius JR, Douaihy A, Kirisci L, Daley DC, Kelly TM. Patient characteristics and treatment implications of marijuana abuse among bipolar alcoholics: results from a double blind, placebo-controlled study. Addict Behav. 2005 Oct; 30(9):1702-8. PMID: 16098680.
      Citations: 3     Fields:    Translation:Humans
    41. Weiss RD, Ostacher MJ, Otto MW, Calabrese JR, Fossey M, Wisniewski SR, Bowden CL, Nierenberg AA, Pollack MH, Salloum IM, Simon NM, Thase ME, Sachs GS. Does recovery from substance use disorder matter in patients with bipolar disorder? J Clin Psychiatry. 2005 Jun; 66(6):730-5; quiz 808-9. PMID: 15960566.
      Citations: 34     Fields:    Translation:HumansCTClinical Trials
    42. Cornelius JR, Clark DB, Bukstein OG, Kelly TM, Salloum IM, Wood DS. Fluoxetine in adolescents with comorbid major depression and an alcohol use disorder: a 3-year follow-up study. Addict Behav. 2005 May; 30(4):807-14. PMID: 15833583.
      Citations: 6     Fields:    Translation:Humans
    43. Kilbourne AM, Cornelius JR, Han X, Haas GL, Salloum I, Conigliaro J, Pincus HA. General-medical conditions in older patients with serious mental illness. Am J Geriatr Psychiatry. 2005 Mar; 13(3):250-4. PMID: 15728757.
      Citations: 20     Fields:    Translation:Humans
    44. Cornelius JR, Clark DB, Bukstein OG, Salloum IM. Treatment of co-occurring alcohol, drug, and psychiatric disorders. Recent Dev Alcohol. 2005; 17:349-65. PMID: 15789875.
      Citations: 11     Fields:    Translation:Humans
    45. Salloum IM, Cornelius JR, Daley DC, Kirisci L, Himmelhoch JM, Thase ME. Efficacy of valproate maintenance in patients with bipolar disorder and alcoholism: a double-blind placebo-controlled study. Arch Gen Psychiatry. 2005 Jan; 62(1):37-45. PMID: 15630071.
      Citations: 70     Fields:    Translation:HumansCTClinical Trials
    46. Kilbourne AM, Cornelius JR, Han X, Pincus HA, Shad M, Salloum I, Conigliaro J, Haas GL. Burden of general medical conditions among individuals with bipolar disorder. Bipolar Disord. 2004 Oct; 6(5):368-73. PMID: 15383128.
      Citations: 103     Fields:    Translation:Humans
    47. Anton RF, Pettinati H, Zweben A, Kranzler HR, Johnson B, Bohn MJ, McCaul ME, Anthenelli R, Salloum I, Galloway G, Garbutt J, Swift R, Gastfriend D, Kallio A, Karhuvaara S. A multi-site dose ranging study of nalmefene in the treatment of alcohol dependence. J Clin Psychopharmacol. 2004 Aug; 24(4):421-8. PMID: 15232334.
      Citations: 28     Fields:    Translation:HumansCTClinical Trials
    48. Cornelius JR, Maisto SA, Martin CS, Bukstein OG, Salloum IM, Daley DC, Wood DS, Clark DB. Major depression associated with earlier alcohol relapse in treated teens with AUD. Addict Behav. 2004 Jul; 29(5):1035-8. PMID: 15219354.
      Citations: 35     Fields:    Translation:Humans
    49. Cornelius JR, Clark DB, Salloum IM, Bukstein OG, Kelly TM. Interventions in suicidal alcoholics. Alcohol Clin Exp Res. 2004 May; 28(5 Suppl):89S-96S. PMID: 15166640.
      Citations: 14     Fields:    Translation:Humans
    50. Le Fauve CE, Litten RZ, Randall CL, Moak DH, Salloum IM, Green AI. Pharmacological treatment of alcohol abuse/dependence with psychiatric comorbidity. Alcohol Clin Exp Res. 2004 Feb; 28(2):302-12. PMID: 15112938.
      Citations: 12     Fields:    Translation:HumansAnimals
    51. Cornelius JR, Bukstein OG, Salloum IM, Kelly TM, Wood DS, Clark DB. Fluoxetine in depressed AUD adolescents: a 1-year follow-up evaluation. J Child Adolesc Psychopharmacol. 2004; 14(1):33-8. PMID: 15142389.
      Citations: 7     Fields:    Translation:Humans
    52. Salloum IM, Douaihy A, Ndimbie OK, Kirisci L. Concurrent alcohol and cocaine dependence impact on physical health among psychiatric patients. J Addict Dis. 2004; 23(2):71-81. PMID: 15132343.
      Citations: 8     Fields:    Translation:Humans
    53. Douaihy AB, Jou RJ, Gorske T, Salloum IM. Triple diagnosis: dual diagnosis and HIV disease, part 2. AIDS Read. 2003 Aug; 13(8):375-82. PMID: 14524322.
      Citations: 5     Fields:    Translation:Humans
    54. Douaihy AB, Jou RJ, Gorske T, Salloum IM. Triple diagnosis: dual diagnosis and HIV disease, Part 1. AIDS Read. 2003 Jul; 13(7):331-2, 339-41. PMID: 12889451.
      Citations: 8     Fields:    Translation:Humans
    55. Weiss RD, Griffin ML, Mazurick C, Berkman B, Gastfriend DR, Frank A, Barber JP, Blaine J, Salloum I, Moras K. The relationship between cocaine craving, psychosocial treatment, and subsequent cocaine use. Am J Psychiatry. 2003 Jul; 160(7):1320-5. PMID: 12832248.
      Citations: 73     Fields:    Translation:HumansCTClinical Trials
    56. Woody GE, Gallop R, Luborsky L, Blaine J, Frank A, Salloum IM, Gastfriend D, Crits-Christoph P. HIV risk reduction in the National Institute on Drug Abuse Cocaine Collaborative Treatment Study. J Acquir Immune Defic Syndr. 2003 May 01; 33(1):82-7. PMID: 12792359.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    57. Cornelius JR, Maisto SA, Pollock NK, Martin CS, Salloum IM, Lynch KG, Clark DB. Rapid relapse generally follows treatment for substance use disorders among adolescents. Addict Behav. 2003 Mar; 28(2):381-6. PMID: 12573689.
      Citations: 52     Fields:    Translation:Humans
    58. Cornelius JR, Bukstein O, Salloum I, Clark D. Alcohol and psychiatric comorbidity. Recent Dev Alcohol. 2003; 16:361-74. PMID: 12638646.
      Citations: 22     Fields:    Translation:Humans
    59. Salloum IM, Cornelius JR, Mezzich JE, Kirisci L. Impact of concurrent alcohol misuse on symptom presentation of acute mania at initial evaluation. Bipolar Disord. 2002 Dec; 4(6):418-21. PMID: 12519103.
      Citations: 16     Fields:    Translation:Humans
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