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Somiranjan Ghosh

TitleAssistant Professor
Faculty RankAssistant Professor
InstitutionHoward University
DepartmentPediatrics and Child Health
AddressHoward University College of Medicine
Washington DC 20059
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    Collapse Biography 
    Collapse education and training
    Calcutta University, Kolkata, IndiaMS09/1989Marine Science
    Calcutta University, KOlkata, IndiaPhD04/2000Drug Discovery
    National Cancer Institure (NIH), Bethesda, MarylandPostDoctoral Fellow08/2004Cancer Treatmnet & Detection

    Collapse Overview 
    Collapse overview
    Dr Ghosh completed his Graduate Studies from Calcutta University, India, before he joins National Cancer Institute/NIH, Bethesda, where he completed his postdoctoral research. I moved to Howard University, Washington DC, and started working at Biology Department, with an additional position of Assistant Professor at the in the Department of Pediatrics and Child Health, College of Medicine at Howard University. He is an exposure biologist/scientist with more than 20 years working experience in Academics. As evidence of my accomplishments, I hold 1 patent, and I published 35+ research papers in peer-reviewed journals, with numerous national and international presentations. I am also an in the Editorial Board of 16 Journals. I am also the also the Lead PI of a recently funded NIGMS-RCMI RO1 and NCI P-20 projects to advance the identification and understanding of the role of Type 2 Diabetes in African American population of USA determining the their health and disease (Gene Environment Interactions, GxE), provide fresh perspectives, and bring new understanding to problems in environmental health through application of innovative knowledge and problem-solving technologies.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mondal T, Noreen Z, Loffredo CA, Johnson J, Bhatti A, Nunlee-Bland G, Quartey R, Howell CD, Moses G, Nnanabu T, Cotin ST, Clark M, Chandra V, Jana SS, Kwabi-Addo B, Korba BE, Shahzad S, Bhatti MF, Ghosh S. Transcriptomic Analysis of Alzheimer's Disease Pathways in a Pakistani Population. J Alzheimers Dis Rep. 2024; 8(1):479-493. PMID: 38549628.
      Citations:    
    2. Creighton CJ, Zhang F, Zhang Y, Castro P, Hu R, Islam M, Ghosh S, Ittmann M, Kwabi-Addo B. Comparative and integrative analysis of transcriptomic and epigenomic-wide DNA methylation changes in African American prostate cancer. Epigenetics. 2023 12; 18(1):2180585. PMID: 37279148.
      Citations: 2     Fields:    Translation:HumansCells
    3. Mondal T, Smith CI, Loffredo CA, Quartey R, Moses G, Howell CD, Korba B, Kwabi-Addo B, Nunlee-Bland G, R Rucker L, Johnson J, Ghosh S. Transcriptomics of MASLD Pathobiology in African American Patients in the Washington DC Area ?. Int J Mol Sci. 2023 Nov 23; 24(23). PMID: 38068980.
      Citations:    Fields:    Translation:Humans
    4. Moore MM, Ayuk MA, Johnson AA, Sims T, Haamen S, Haidara R, Allen AD, Dickson LA, Ghosh S, Gugssa A, Ullah H, Bassey GB, Fernando LM, London LY, Irabor EG, Roy SD, Quagraine BK, Smith M, Anderson WA, Robinson CJ. Complete Genome Sequences of Subcluster C1 Mycobacteriophages Blackbrain, Cactojaque, Kboogie, Trinitium, and YoungMoneyMata. Microbiol Resour Announc. 2023 Jun 20; 12(6):e0025323. PMID: 37255446.
      Citations:    
    5. Cagle E, Lake B, Banerjee A, Cuffee J, Banerjee N, Gilmartin D, Liverman M, Brown S, Armstrong E, Bhattacharya S, Ghosh S, Mandal T, Banerjee H. Analysis of Differential Gene Expression and Core Canonical Pathways Involved in the Epithelial to Mesenchymal Transition of Triple Negative Breast Cancer Cells by Ingenuity Pathway Analysis. Comput Mol Biosci. 2023 Jun; 13(2):21-34. PMID: 37538932.
      Citations:    
    6. Mondal T, Loffredo CA, Simhadri J, Nunlee-Bland G, Korba B, Johnson J, Cotin S, Moses G, Quartey R, Howell CD, Noreen Z, Arif M, Ghosh S. Insights on the pathogenesis of type 2 diabetes as revealed by signature genomic classifiers in an African American population in the Washington, DC area. Diabetes Metab Res Rev. 2023 01; 39(1):e3589. PMID: 36331813.
      Citations: 3     Fields:    Translation:Humans
    7. Arif M, Mondal T, Majeed A, Loffredo CA, Korba BE, Ghosh S. Peroxisome Proliferator-Activated Receptor-a (PPARa) Expression in a Clinical Population of Pakistani Patients with Type 2 Diabetes and Dyslipidemia. Int J Mol Sci. 2022 Sep 16; 23(18). PMID: 36142760.
      Citations: 1     Fields:    Translation:Humans
    8. London LY, Ayuk MA, Black AC, Cheung L, Robinson DM, Thomas DN, Warner MH, Allen AD, Ghosh S, Gugssa A, Ullah H, Bassey GB, Fernando LM, Moore MM, Oliver JJ, Irabor EG, Roy SD, Quagraine BK, Smith M, Anderson WA, Robinson CJ. Complete Genome Sequences of Mycobacteriophages SynergyX, Abinghost, Bananafish, and Delton. Microbiol Resour Announc. 2022 Aug 18; 11(8):e0028622. PMID: 35863046.
      Citations:    
    9. Mondal T, Loffredo CA, Trnovec T, Palkovicova Murinova L, Noreen Z, Nnanabu T, Conka K, Drobna B, Ghosh S. Gene expression signatures in PCB-exposed Slovak children in relation to their environmental exposures and socio-physical characteristics. Environ Sci Pollut Res Int. 2022 Aug; 29(40):60531-60541. PMID: 35420343.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    10. Krauss C, Aurelus C, Johnston K, Hedley J, Banerjee S, Wisniewski S, Reaves Q, Dia K, Brown S, Bartlet V, Gavin S, Cuffee J, Banerjee N, Rawat K, Mandal S, Abedin Z, Ghosh S, Banerjee H. A Study of Differential Gene Expression and Core Canonical Pathways Involved in Rhenium Ligand Treated Epithelial Mesenchymal Transition (EMT) Induced A549 Lung Cancer Cell Lines by INGENUITY Software System. Comput Mol Biosci. 2022 Mar; 12(1):12-19. PMID: 35342659.
      Citations:    
    11. Tailor K, Paul J, Ghosh S, Kumari N, Kwabi-Addo B. RASAL2 suppresses the proliferative and invasive ability of PC3 prostate cancer cells. Oncotarget. 2021 Dec 21; 12(26):2489-2499. PMID: 34966481.
      Citations:    Fields:    
    12. Mondal T, Nautiyal A, Ghosh S, Loffredo CA, Mitra D, Saha C, Dey SK. An evaluation of DNA double strand break formation and excreted guanine species post whole body PET/CT procedure. J Radiat Res. 2021 Jul 10; 62(4):590-599. PMID: 34037214.
      Citations:    Fields:    Translation:Humans
    13. London LY, Ayuk MA, Effiom D, Fashina F, Louis BJ, Tolsma SS, Allen AD, Dickson LA, Ghosh S, Gugssa A, Ullah H, Bassey GB, Fernando LM, Moore MM, Oliver JJ, Irabor EG, Roy SD, Quagraine BK, Smith M, Anderson WA, Robinson CJ. Complete Genome Sequences of Mycobacteriophages Dallas and Jonghyun. Microbiol Resour Announc. 2021 Jul 08; 10(27):e0030421. PMID: 34236221.
      Citations:    
    14. Simhadri JJ, Loffredo CA, Trnovec T, Murinova LP, Nunlee-Bland G, Koppe JG, Schoeters G, Jana SS, Ghosh S. Biomarkers of metabolic disorders and neurobehavioral diseases in a PCB- exposed population: What we learned and the implications for future research. Environ Res. 2020 12; 191:110211. PMID: 32937175.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    15. Noreen Z, Loffredo CA, Bhatti A, Simhadri JJ, Nunlee-Bland G, Nnanabu T, John P, Khan JS, Ghosh S. Transcriptional Profiling and Biological Pathway(s) Analysis of Type 2 Diabetes Mellitus in a Pakistani Population. Int J Environ Res Public Health. 2020 08 13; 17(16). PMID: 32823525.
      Citations: 2     Fields:    Translation:HumansCells
    16. Banerjee H, Krauss C, Worthington M, Banerjee N, Walker RS, Hodges S, Chen L, Rawat K, Dasgupta S, Ghosh S, Mandal S. Differential expression of efferocytosis and phagocytosis associated genes in tumor associated macrophages exposed to African American patient derived prostate cancer microenvironment. J Solid Tumors. 2019 Oct; 9(2):22-27. PMID: 31447959.
      Citations:    
    17. Halder D, Saha S, Singh RK, Ghosh I, Mallick D, Dey SK, Ghosh A, Das BB, Ghosh S, Jana SS. Nonmuscle myosin IIA and IIB differentially modulate migration and alter gene expression in primary mouse tumorigenic cells. Mol Biol Cell. 2019 06 01; 30(12):1463-1476. PMID: 30995168.
      Citations: 6     Fields:    Translation:Animals
    18. Noreen Z, DeJesus J, Bhatti A, Loffredo CA, John P, Khan JS, Nunlee-Bland G, Ghosh S. Epidemiological Investigation of Type 2 Diabetes and Alzheimer's Disease in a Pakistani Population. Int J Environ Res Public Health. 2018 07 26; 15(8). PMID: 30049934.
      Citations: 4     Fields:    Translation:Humans
    19. Ghosh S, Loffredo CA, Mitra PS, Trnovec T, Palkovicova Murinova L, Sovcikova E, Hoffman EP, Makambi KH, Dutta SK. PCB exposure and potential future cancer incidence in Slovak children: an assessment from molecular finger printing by Ingenuity Pathway Analysis (IPA?) derived from experimental and epidemiological investigations. Environ Sci Pollut Res Int. 2018 Jun; 25(17):16493-16507. PMID: 29143255.
      Citations: 13     Fields:    Translation:HumansCells
    20. Ghosh S, Dutta S, Thorne G, Boston A, Barfield A, Banerjee N, Walker R, Banerjee HN. Core Canonical Pathways Involved in Developing Human Glioblastoma Multiforme (GBM). Int J Sci Res Sci Eng Technol. 2017 Feb; 3(1):458-465. PMID: 28523289.
      Citations:    
    21. Ghosh S, Mitra PS, Loffredo CA, Trnovec T, Murinova L, Sovcikova E, Ghimbovschi S, Zang S, Hoffman EP, Dutta SK. Transcriptional profiling and biological pathway analysis of human equivalence PCB exposure in vitro: indicator of disease and disorder development in humans. Environ Res. 2015 Apr; 138:202-16. PMID: 25725301.
      Citations: 7     Fields:    Translation:HumansCellsPHPublic Health
    22. Ghosh S, Murinova L, Trnovec T, Loffredo CA, Washington K, Mitra PS, Dutta SK. Biomarkers linking PCB exposure and obesity. Curr Pharm Biotechnol. 2014; 15(11):1058-68. PMID: 25420728.
      Citations: 28     Fields:    Translation:HumansPHPublic Health
    23. Ghosh S, Trnovec T, Palkovicova L, Hoffman EP, Washington K, Dutta SK. Status of LEPR Gene in PCB-exposed Population: A Quick Look. Int J Hum Genet. 2013 Mar; 13(1):27-32. PMID: 23741107.
      Citations:    
    24. Mitra PS, Ghosh S, Zang S, Sonneborn D, Hertz-Picciotto I, Trnovec T, Palkovicova L, Sovcikova E, Ghimbovschi S, Hoffman EP, Dutta SK. Analysis of the toxicogenomic effects of exposure to persistent organic pollutants (POPs) in Slovakian girls: correlations between gene expression and disease risk. Environ Int. 2012 Feb; 39(1):188-99. PMID: 22208759.
      Citations: 17     Fields:    Translation:HumansCells
    25. Dutta SK, Mitra PS, Ghosh S, Zang S, Sonneborn D, Hertz-Picciotto I, Trnovec T, Palkovicova L, Sovcikova E, Ghimbovschi S, Hoffman EP. Differential gene expression and a functional analysis of PCB-exposed children: understanding disease and disorder development. Environ Int. 2012 Apr; 40:143-154. PMID: 21855147.
      Citations: 15     Fields:    Translation:HumansCells
    26. Ghosh S, Zang S, Mitra PS, Ghimbovschi S, Hoffman EP, Dutta SK. Global gene expression and Ingenuity biological functions analysis on PCBs 153 and 138 induced human PBMC in vitro reveals differential mode(s) of action in developing toxicities. Environ Int. 2011 Jul; 37(5):838-57. PMID: 21470681.
      Citations: 14     Fields:    Translation:HumansCells
    27. Ghosh S, De S, Chen Y, Sutton DC, Ayorinde FO, Dutta SK. Polychlorinated biphenyls (PCB-153) and (PCB-77) absorption in human liver (HepG2) and kidney (HK2) cells in vitro: PCB levels and cell death. Environ Int. 2010 Nov; 36(8):893-900. PMID: 20723988.
      Citations: 12     Fields:    Translation:HumansCells
    28. De S, Ghosh S, Chatterjee R, Chen YQ, Moses L, Kesari A, Hoffman EP, Dutta SK. PCB congener specific oxidative stress response by microarray analysis using human liver cell line. Environ Int. 2010 Nov; 36(8):907-17. PMID: 20638727.
      Citations: 18     Fields:    Translation:HumansCells
    29. Dutta SK, Ghosh S, De S, Hoffman EP. CYP1A1 and MT1K are congener specific biomarker genes for liver diseases induced by PCBs. Environ Toxicol Pharmacol. 2008 Mar; 25(2):218-21. PMID: 21783860.
      Citations: 10     Fields:    
    30. Ghosh S, De S, Dutta SK. Altered protein expressions in chronic PCB-153-induced human liver (HepG2) cells. Int J Toxicol. 2007 May-Jun; 26(3):203-12. PMID: 17564901.
      Citations: 14     Fields:    Translation:HumansCells
    31. De S, Ghosh S, Dutta SK. Congener specific polychlorinated biphenyl metabolism by human intestinal microbe Clostridium species: Comparison with human liver cell line-HepG2. Indian J Microbiol. 2006 Sep; 46(3):199-207. PMID: 25838614.
      Citations:    
    32. Dasmahapatra GP, Didolkar P, Alley MC, Ghosh S, Sausville EA, Roy KK. In vitro combination treatment with perifosine and UCN-01 demonstrates synergism against prostate (PC-3) and lung (A549) epithelial adenocarcinoma cell lines. Clin Cancer Res. 2004 Aug 01; 10(15):5242-52. PMID: 15297428.
      Citations: 18     Fields:    Translation:HumansCells
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