Roger Simon to Brain Ischemia
This is a "connection" page, showing publications Roger Simon has written about Brain Ischemia.
Connection Strength
7.067
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Zha XM, Xiong ZG, Simon RP. pH and proton-sensitive receptors in brain ischemia. J Cereb Blood Flow Metab. 2022 08; 42(8):1349-1363.
Score: 0.708
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Simon R, Meller R, Yang T, Pearson A, Wilson G. Enhancing Base Excision Repair of Mitochondrial DNA to Reduce Ischemic Injury Following Reperfusion. Transl Stroke Res. 2019 12; 10(6):664-671.
Score: 0.564
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Meller R, Simon RP. A critical review of mechanisms regulating remote preconditioning-induced brain protection. J Appl Physiol (1985). 2015 Nov 15; 119(10):1135-42.
Score: 0.440
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Meller R, Simon RP. Tolerance to ischemia - an increasingly complex biology. Transl Stroke Res. 2013 Feb; 4(1):40-50.
Score: 0.374
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Chai S, Li M, Branigan D, Xiong ZG, Simon RP. Activation of acid-sensing ion channel 1a (ASIC1a) by surface trafficking. J Biol Chem. 2010 Apr 23; 285(17):13002-11.
Score: 0.307
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Johnson MB, Simon RP. Endogenous neuroprotective mechanisms in the brain. Epilepsia. 2009 Dec; 50 Suppl 12:3-4.
Score: 0.302
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Sato Y, Meller R, Yang T, Taki W, Simon RP. Stereo-selective neuroprotection against stroke with vitamin A derivatives. Brain Res. 2008 Nov 19; 1241:188-92.
Score: 0.278
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Pignataro G, Meller R, Inoue K, Ordonez AN, Ashley MD, Xiong Z, Gala R, Simon RP. In vivo and in vitro characterization of a novel neuroprotective strategy for stroke: ischemic postconditioning. J Cereb Blood Flow Metab. 2008 Feb; 28(2):232-41.
Score: 0.259
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Stenzel-Poore MP, Stevens SL, King JS, Simon RP. Preconditioning reprograms the response to ischemic injury and primes the emergence of unique endogenous neuroprotective phenotypes: a speculative synthesis. Stroke. 2007 Feb; 38(2 Suppl):680-5.
Score: 0.248
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Xiong ZG, Chu XP, Simon RP. Acid sensing ion channels--novel therapeutic targets for ischemic brain injury. Front Biosci. 2007 Jan 01; 12:1376-86.
Score: 0.247
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Simon RP. Acidotoxicity trumps excitotoxicity in ischemic brain. Arch Neurol. 2006 Oct; 63(10):1368-71.
Score: 0.242
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Meller R, Minami M, Cameron JA, Impey S, Chen D, Lan JQ, Henshall DC, Simon RP. CREB-mediated Bcl-2 protein expression after ischemic preconditioning. J Cereb Blood Flow Metab. 2005 Feb; 25(2):234-46.
Score: 0.216
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Stenzel-Poore MP, Stevens SL, Simon RP. Genomics of preconditioning. Stroke. 2004 Nov; 35(11 Suppl 1):2683-6.
Score: 0.211
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Xiong ZG, Zhu XM, Chu XP, Minami M, Hey J, Wei WL, MacDonald JF, Wemmie JA, Price MP, Welsh MJ, Simon RP. Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels. Cell. 2004 Sep 17; 118(6):687-98.
Score: 0.210
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Zhou A, Minami M, Zhu X, Bae S, Minthorne J, Lan J, Xiong ZG, Simon RP. Altered biosynthesis of neuropeptide processing enzyme carboxypeptidase E after brain ischemia: molecular mechanism and implication. J Cereb Blood Flow Metab. 2004 Jun; 24(6):612-22.
Score: 0.206
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Stenzel-Poore MP, Stevens SL, Xiong Z, Lessov NS, Harrington CA, Mori M, Meller R, Rosenzweig HL, Tobar E, Shaw TE, Chu X, Simon RP. Effect of ischaemic preconditioning on genomic response to cerebral ischaemia: similarity to neuroprotective strategies in hibernation and hypoxia-tolerant states. Lancet. 2003 Sep 27; 362(9389):1028-37.
Score: 0.197
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Chen D, Jin K, Kawaguchi K, Nakayama M, Zhou X, Xiong Z, Zhou A, Mao XO, Greenberg DA, Graham SH, Simon RP. Ero1-L, an ischemia-inducible gene from rat brain with homology to global ischemia-induced gene 11 (Giig11), is localized to neuronal dendrites by a dispersed identifier (ID) element-dependent mechanism. J Neurochem. 2003 May; 85(3):670-9.
Score: 0.191
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Flippo KH, Lin Z, Dickey AS, Zhou X, Dhanesha NA, Walters GC, Liu Y, Merrill RA, Meller R, Simon RP, Chauhan AK, Usachev YM, Strack S. Deletion of a Neuronal Drp1 Activator Protects against Cerebral Ischemia. J Neurosci. 2020 04 08; 40(15):3119-3129.
Score: 0.154
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Brager AJ, Yang T, Ehlen JC, Simon RP, Meller R, Paul KN. Sleep Is Critical for Remote Preconditioning-Induced Neuroprotection. Sleep. 2016 Nov 01; 39(11):2033-2040.
Score: 0.122
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Jiang N, Wu J, Leng T, Yang T, Zhou Y, Jiang Q, Wang B, Hu Y, Ji YH, Simon RP, Chu XP, Xiong ZG, Zha XM. Region specific contribution of ASIC2 to acidosis-and ischemia-induced neuronal injury. J Cereb Blood Flow Metab. 2017 Feb; 37(2):528-540.
Score: 0.120
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Li MH, Leng TD, Feng XC, Yang T, Simon RP, Xiong ZG. Modulation of Acid-sensing Ion Channel 1a by Intracellular pH and Its Role in Ischemic Stroke. J Biol Chem. 2016 08 26; 291(35):18370-83.
Score: 0.119
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Stevens SL, Leung PY, Vartanian KB, Gopalan B, Yang T, Simon RP, Stenzel-Poore MP. Multiple preconditioning paradigms converge on interferon regulatory factor-dependent signaling to promote tolerance to ischemic brain injury. J Neurosci. 2011 Jun 08; 31(23):8456-63.
Score: 0.084
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Thompson S, Pearson AN, Ashley MD, Jessick V, Murphy BM, Gafken P, Henshall DC, Morris KT, Simon RP, Meller R. Identification of a novel Bcl-2-interacting mediator of cell death (Bim) E3 ligase, tripartite motif-containing protein 2 (TRIM2), and its role in rapid ischemic tolerance-induced neuroprotection. J Biol Chem. 2011 Jun 03; 286(22):19331-9.
Score: 0.083
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Zhou A, Simon RP, David L. Nascent proteomes of ischemic-injured and ischemic-tolerant neuronal cells. Int J Comput Biol Drug Des. 2011; 4(1):40-55.
Score: 0.082
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Stapels M, Piper C, Yang T, Li M, Stowell C, Xiong ZG, Saugstad J, Simon RP, Geromanos S, Langridge J, Lan JQ, Zhou A. Polycomb group proteins as epigenetic mediators of neuroprotection in ischemic tolerance. Sci Signal. 2010 Mar 02; 3(111):ra15.
Score: 0.077
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Zhan S, Zhao H, J White A, Minami M, Pignataro G, Yang T, Zhu X, Lan J, Xiong Z, Steiner DF, Simon RP, Zhou A. Defective neuropeptide processing and ischemic brain injury: a study on proprotein convertase 2 and its substrate neuropeptide in ischemic brains. J Cereb Blood Flow Metab. 2009 Apr; 29(4):698-706.
Score: 0.071
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Doyle KP, Simon RP, Stenzel-Poore MP. Mechanisms of ischemic brain damage. Neuropharmacology. 2008 Sep; 55(3):310-8.
Score: 0.066
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Stevens SL, Ciesielski TM, Marsh BJ, Yang T, Homen DS, Boule JL, Lessov NS, Simon RP, Stenzel-Poore MP. Toll-like receptor 9: a new target of ischemic preconditioning in the brain. J Cereb Blood Flow Metab. 2008 May; 28(5):1040-7.
Score: 0.066
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Xiong ZG, Pignataro G, Li M, Chang SY, Simon RP. Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases. Curr Opin Pharmacol. 2008 Feb; 8(1):25-32.
Score: 0.065
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Rosenzweig HL, Minami M, Lessov NS, Coste SC, Stevens SL, Henshall DC, Meller R, Simon RP, Stenzel-Poore MP. Endotoxin preconditioning protects against the cytotoxic effects of TNFalpha after stroke: a novel role for TNFalpha in LPS-ischemic tolerance. J Cereb Blood Flow Metab. 2007 Oct; 27(10):1663-74.
Score: 0.062
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Pignataro G, Studer FE, Wilz A, Simon RP, Boison D. Neuroprotection in ischemic mouse brain induced by stem cell-derived brain implants. J Cereb Blood Flow Metab. 2007 May; 27(5):919-27.
Score: 0.061
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Pignataro G, Simon RP, Xiong ZG. Prolonged activation of ASIC1a and the time window for neuroprotection in cerebral ischaemia. Brain. 2007 Jan; 130(Pt 1):151-8.
Score: 0.061
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Pignataro G, Simon RP, Boison D. Transgenic overexpression of adenosine kinase aggravates cell death in ischemia. J Cereb Blood Flow Metab. 2007 Jan; 27(1):1-5.
Score: 0.059
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Li W, Luo Y, Zhang F, Signore AP, Gobbel GT, Simon RP, Chen J. Ischemic preconditioning in the rat brain enhances the repair of endogenous oxidative DNA damage by activating the base-excision repair pathway. J Cereb Blood Flow Metab. 2006 Feb; 26(2):181-98.
Score: 0.058
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Meller R, Stevens SL, Minami M, Cameron JA, King S, Rosenzweig H, Doyle K, Lessov NS, Simon RP, Stenzel-Poore MP. Neuroprotection by osteopontin in stroke. J Cereb Blood Flow Metab. 2005 Feb; 25(2):217-25.
Score: 0.054
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Jin K, Minami M, Xie L, Sun Y, Mao XO, Wang Y, Simon RP, Greenberg DA. Ischemia-induced neurogenesis is preserved but reduced in the aged rodent brain. Aging Cell. 2004 Dec; 3(6):373-7.
Score: 0.053
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Rosenzweig HL, Lessov NS, Henshall DC, Minami M, Simon RP, Stenzel-Poore MP. Endotoxin preconditioning prevents cellular inflammatory response during ischemic neuroprotection in mice. Stroke. 2004 Nov; 35(11):2576-81.
Score: 0.053
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Cao G, Xiao M, Sun F, Xiao X, Pei W, Li J, Graham SH, Simon RP, Chen J. Cloning of a novel Apaf-1-interacting protein: a potent suppressor of apoptosis and ischemic neuronal cell death. J Neurosci. 2004 Jul 07; 24(27):6189-201.
Score: 0.052
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Sun H, Yang T, Simon R, Xiong ZG, Leng T. Cholestane-3?,5a,6?-Triol Inhibits Acid-Sensing Ion Channels and Reduces Acidosis-Mediated Ischemic Brain Injury. Stroke. 2024 Jun; 55(6):1660-1671.
Score: 0.051
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Dirnagl U, Simon RP, Hallenbeck JM. Ischemic tolerance and endogenous neuroprotection. Trends Neurosci. 2003 May; 26(5):248-54.
Score: 0.048
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Chen D, Minami M, Henshall DC, Meller R, Kisby G, Simon RP. Upregulation of mitochondrial base-excision repair capability within rat brain after brief ischemia. J Cereb Blood Flow Metab. 2003 Jan; 23(1):88-98.
Score: 0.047
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Jin K, Nagayama T, Mao X, Kawaguchi K, Hickey RW, Greenberg DA, Simon RP, Graham SH. Two caspase-2 transcripts are expressed in rat hippocampus after global cerebral ischemia. J Neurochem. 2002 Apr; 81(1):25-35.
Score: 0.044
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Chang SY, DeVera C, Yang Z, Yang T, Song L, McDowell A, Xiong ZG, Simon R, Zhou A. Hippocampal changes in mice lacking an active prohormone convertase 2. Hippocampus. 2020 07; 30(7):715-723.
Score: 0.038
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Lusardi TA, Farr CD, Faulkner CL, Pignataro G, Yang T, Lan J, Simon RP, Saugstad JA. Ischemic preconditioning regulates expression of microRNAs and a predicted target, MeCP2, in mouse cortex. J Cereb Blood Flow Metab. 2010 Apr; 30(4):744-56.
Score: 0.019