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Qian-Jin Zhang

TitleFaculty, Department of Biology
Faculty RankAssociate Professor
InstitutionXavier University of Louisiana
DepartmentBiology
AddressXavier University of Louisiana
1 Drexel Drive
Biology
New Orleans LA 70125
Phone5045205503
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Li Y, Zhang J, Gao X, Zhang QC. Tissue module discovery in single-cell-resolution spatial transcriptomics data via cell-cell interaction-aware cell embedding. Cell Syst. 2024 Jun 19; 15(6):578-592.e7. PMID: 38823396.
      Citations:    Fields:    Translation:HumansAnimalsCells
    2. Yang R, Pan M, Guo J, Huang Y, Zhang QC, Deng T, Wang J. Mapping of the influenza A virus genome RNA structure and interactions reveals essential elements of viral replication. Cell Rep. 2024 Mar 26; 43(3):113833. PMID: 38416642.
      Citations:    Fields:    Translation:HumansAnimalsCells
    3. Zhang X, Zhan X, Bian T, Yang F, Li P, Lu Y, Xing Z, Fan R, Zhang QC, Shi Y. Structural insights into branch site proofreading by human spliceosome. Nat Struct Mol Biol. 2024 May; 31(5):835-845. PMID: 38196034.
      Citations: 4     Fields:    Translation:HumansCells
    4. Huang W, Xiong T, Zhao Y, Heng J, Han G, Wang P, Zhao Z, Shi M, Li J, Wang J, Wu Y, Liu F, Xi JJ, Wang Y, Zhang QC. Computational prediction and experimental validation identify functionally conserved lncRNAs from zebrafish to human. Nat Genet. 2024 Jan; 56(1):124-135. PMID: 38195860.
      Citations: 2     Fields:    Translation:HumansAnimals
    5. Xiang Y, Huang W, Tan L, Chen T, He Y, Irving PS, Weeks KM, Zhang QC, Dong X. Pervasive downstream RNA hairpins dynamically dictate start-codon selection. Nature. 2023 Sep; 621(7978):423-430. PMID: 37674078.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    6. Xu Y, Zhu J, Huang W, Xu K, Yang R, Zhang QC, Sun L. PrismNet: predicting protein-RNA interaction using in?vivo RNA structural information. Nucleic Acids Res. 2023 07 05; 51(W1):W468-W477. PMID: 37140045.
      Citations: 2     Fields:    Translation:Cells
    7. Deng J, Fang X, Huang L, Li S, Xu L, Ye K, Zhang J, Zhang K, Zhang QC. RNA structure determination: From 2D to 3D. Fundam Res. 2023 Sep; 3(5):727-737. PMID: 38933295.
      Citations:    
    8. Deng P, Tan SQ, Yang QY, Fu L, Wu Y, Zhu HZ, Sun L, Bao Z, Lin Y, Zhang QC, Wang H, Wang J, Liu JG. Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon. Cell. 2023 06 22; 186(13):2865-2879.e20. PMID: 37301196.
      Citations: 9     Fields:    Translation:Cells
    9. Kang B, Mottamal M, Zhong Q, Bratton M, Zhang C, Guo S, Hossain A, Ma P, Zhang Q, Wang G, Payton-Stewart F. Design, Synthesis, and Evaluation of Niclosamide Analogs as Therapeutic Agents for Enzalutamide-Resistant Prostate Cancer. Pharmaceuticals (Basel). 2023 May 12; 16(5). PMID: 37242518.
      Citations:    
    10. Li D, Huang S, Chai Y, Zhao R, Gong J, Zhang QC, Ou G, Wen W. A paternal protein facilitates sperm RNA delivery to regulate zygotic development. Sci China Life Sci. 2023 10; 66(10):2342-2353. PMID: 37160652.
      Citations: 3     Fields:    Translation:AnimalsCells
    11. Li N, Chen S, Xu K, He MT, Dong MQ, Zhang QC, Gao N. Structural basis of membrane skeleton organization in red blood cells. Cell. 2023 04 27; 186(9):1912-1929.e18. PMID: 37044097.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    12. Dai M, Dong Z, Xu K, Zhang QC. CryoRes: Local Resolution Estimation of Cryo-EM Density Maps by Deep Learning. J Mol Biol. 2023 05 01; 435(9):168059. PMID: 36967040.
      Citations: 2     Fields:    Translation:Cells
    13. Huang W, Zhang QC. Prediction of Dynamic RBP-RNA Interactions Using PrismNet. Methods Mol Biol. 2023; 2568:123-132. PMID: 36227565.
      Citations:    Fields:    Translation:Cells
    14. Sun H, Chen Y, Yan K, Shao Y, Zhang QC, Lin Y, Xi Q. Recruitment of TRIM33 to cell-context specific PML nuclear bodies regulates nodal signaling in mESCs. EMBO J. 2023 02 01; 42(3):e112058. PMID: 36524443.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    15. Zhao J, Chow EY, Yeung PY, Zhang QC, Chan TF, Kwok CK. Enhanced transcriptome-wide RNA G-quadruplex sequencing for low RNA input samples with rG4-seq 2.0. BMC Biol. 2022 11 13; 20(1):257. PMID: 36372875.
      Citations: 3     Fields:    Translation:HumansCells
    16. Xiong L, Tian K, Li Y, Ning W, Gao X, Zhang QC. Online single-cell data integration through projecting heterogeneous datasets into a common cell-embedding space. Nat Commun. 2022 10 17; 13(1):6118. PMID: 36253379.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    17. Kong X, Yan K, Deng P, Fu H, Sun H, Huang W, Jiang S, Dai J, Zhang QC, Liu JG, Xi Q. LncRNA-Smad7 mediates cross-talk between Nodal/TGF-? and BMP signaling to regulate cell fate determination of pluripotent and multipotent cells. Nucleic Acids Res. 2022 10 14; 50(18):10526-10543. PMID: 36134711.
      Citations:    Fields:    Translation:Animals
    18. Zhang J, Fei Y, Sun L, Zhang QC. Advances and opportunities in RNA structure experimental determination and computational modeling. Nat Methods. 2022 10; 19(10):1193-1207. PMID: 36203019.
      Citations: 26     Fields:    Translation:Cells
    19. Hu W, Zeng H, Shi Y, Zhou C, Huang J, Jia L, Xu S, Feng X, Zeng Y, Xiong T, Huang W, Sun P, Chang Y, Li T, Fang C, Wu K, Cai L, Ni W, Li Y, Yang Z, Zhang QC, Chian R, Chen Z, Liang X, Kee K. Single-cell transcriptome and translatome dual-omics reveals potential mechanisms of human oocyte maturation. Nat Commun. 2022 08 30; 13(1):5114. PMID: 36042231.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    20. Sun Y, Yan K, Wang Y, Xu C, Wang D, Zhou W, Guo S, Han Y, Tang L, Shao Y, Shan S, Zhang QC, Tang Y, Zhang L, Xi Q. Context-dependent tumor-suppressive BMP signaling in diffuse intrinsic pontine glioma regulates stemness through epigenetic regulation of CXXC5. Nat Cancer. 2022 09; 3(9):1105-1122. PMID: 35915262.
      Citations: 10     Fields:    Translation:HumansCells
    21. Yu B, Li P, Zhang QC, Hou L. Differential analysis of RNA structure probing experiments at nucleotide resolution: uncovering regulatory functions of RNA structure. Nat Commun. 2022 07 22; 13(1):4227. PMID: 35869080.
      Citations: 3     Fields:    Translation:Cells
    22. Xu B, Zhu Y, Cao C, Chen H, Jin Q, Li G, Ma J, Yang SL, Zhao J, Zhu J, Ding Y, Fang X, Jin Y, Kwok CK, Ren A, Wan Y, Wang Z, Xue Y, Zhang H, Zhang QC, Zhou Y. Recent advances in RNA structurome. Sci China Life Sci. 2022 07; 65(7):1285-1324. PMID: 35717434.
      Citations: 12     Fields:    Translation:AnimalsCells
    23. Chen G, Yang Y, Wu QJ, Cao L, Ruan W, Shao C, Jiang L, Tang P, Ma S, Jiang A, Wang Z, Wu K, Zhang QC, Fu XD, Zhou Y. ILF3 represses repeat-derived microRNAs targeting RIG-I mediated type I interferon response. J Mol Biol. 2022 04 15; 434(7):167469. PMID: 35120969.
      Citations: 1     Fields:    Translation:HumansCells
    24. Zhang B, Zhang Y, Xiong L, Li Y, Zhang Y, Zhao J, Jiang H, Li C, Liu Y, Liu X, Liu H, Ping YF, Zhang QC, Zhang Z, Bian XW, Zhao Y, Hu X. CD127 imprints functional heterogeneity to diversify monocyte responses in inflammatory diseases. J Exp Med. 2022 02 07; 219(2). PMID: 35015026.
      Citations: 20     Fields:    Translation:HumansCells
    25. Piao M, Li P, Zeng X, Wang XW, Kang L, Zhang J, Wei Y, Zhang S, Tang L, Zhu J, Kwok CK, Hu X, Zhang QC. An ultra low-input method for global RNA structure probing uncovers Regnase-1-mediated regulation in macrophages. Fundam Res. 2022 Jan; 2(1):2-13. PMID: 38933905.
      Citations:    
    26. Zhang S, Huang W, Ren L, Ju X, Gong M, Rao J, Sun L, Li P, Ding Q, Wang J, Zhang QC. Comparison of viral RNA-host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2. Cell Res. 2022 01; 32(1):9-23. PMID: 34737357.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    27. Li D, Liu Y, Yi P, Zhu Z, Li W, Zhang QC, Li JB, Ou G. RNA editing restricts hyperactive ciliary kinases. Science. 2021 08 27; 373(6558):984-991. PMID: 34446600.
      Citations: 12     Fields:    Translation:AnimalsCells
    28. Wang XW, Liu CX, Chen LL, Zhang QC. RNA structure probing uncovers RNA structure-dependent biological functions. Nat Chem Biol. 2021 07; 17(7):755-766. PMID: 34172967.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    29. Luo QJ, Zhang J, Li P, Wang Q, Zhang Y, Roy-Chaudhuri B, Xu J, Kay MA, Zhang QC. RNA structure probing reveals the structural basis of Dicer binding and cleavage. Nat Commun. 2021 06 07; 12(1):3397. PMID: 34099665.
      Citations: 25     Fields:    Translation:HumansCells
    30. Xu K, Liu N, Xu J, Guo C, Zhao L, Wang HW, Zhang QC. VRmol: an integrative web-based virtual reality system to explore macromolecular structure. Bioinformatics. 2021 05 17; 37(7):1029-1031. PMID: 32745209.
      Citations: 6     Fields:    Translation:Cells
    31. Ju X, Zhu Y, Wang Y, Li J, Zhang J, Gong M, Ren W, Li S, Zhong J, Zhang L, Zhang QC, Zhang R, Ding Q. A novel cell culture system modeling the SARS-CoV-2 life cycle. PLoS Pathog. 2021 03; 17(3):e1009439. PMID: 33711082.
      Citations: 67     Fields:    Translation:HumansCells
    32. Sun L, Xu K, Huang W, Yang YT, Li P, Tang L, Xiong T, Zhang QC. Predicting dynamic cellular protein-RNA interactions by deep learning using in vivo RNA structures. Cell Res. 2021 05; 31(5):495-516. PMID: 33623109.
      Citations: 39     Fields:    Translation:HumansCells
    33. Sun L, Li P, Ju X, Rao J, Huang W, Ren L, Zhang S, Xiong T, Xu K, Zhou X, Gong M, Miska E, Ding Q, Wang J, Zhang QC. In?vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs. Cell. 2021 04 01; 184(7):1865-1883.e20. PMID: 33636127.
      Citations: 104     Fields:    Translation:HumansAnimalsCells
    34. Li P, Zhou X, Xu K, Zhang QC. RASP: an atlas of transcriptome-wide RNA secondary structure probing data. Nucleic Acids Res. 2021 01 08; 49(D1):D183-D191. PMID: 33068412.
      Citations: 22     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    35. Wang H, Lin K, Zhu L, Zhang S, Li L, Liao Y, Zhang B, Yang M, Liu X, Li L, Li S, Yang L, Wang H, Wang Q, Li H, Fu S, Zhang X, Jiang P, Zhang QC, Cheng J, Wang D. Oncogenic lncRNA LINC00973 promotes Warburg effect by enhancing LDHA enzyme activity. Sci Bull (Beijing). 2021 Jul 15; 66(13):1330-1341. PMID: 36654155.
      Citations: 3     Fields:    
    36. Shao Y, Zhang QC. Targeting RNA structures in diseases with small molecules. Essays Biochem. 2020 12 07; 64(6):955-966. PMID: 33078198.
      Citations: 13     Fields:    Translation:Humans
    37. Zhang B, Zhang Y, Xiong L, Li Y, Zhang Y, Zhao J, Jiang H, Li C, Liu Y, Liu X, Liu H, Ping YF, Zhang QC, Zhang Z, Bian XW, Zhao Y, Hu X. CD127 imprints functional heterogeneity to diversify monocyte responses in human inflammatory diseases. bioRxiv. 2020 Nov 10. PMID: 33200127.
      Citations:    
    38. Chowdhury N, Chaudhry S, Hall N, Olverson G, Zhang QJ, Mandal T, Dash S, Kundu A. Targeted Delivery of Doxorubicin Liposomes for Her-2+ Breast Cancer Treatment. AAPS PharmSciTech. 2020 Jul 21; 21(6):202. PMID: 32696338.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    39. Ju X, Xiang G, Gong M, Yang R, Qin J, Li Y, Nan Y, Yang Y, Zhang QC, Ding Q. Identification of functional cis-acting RNA elements in the hepatitis E virus genome required for viral replication. PLoS Pathog. 2020 05; 16(5):e1008488. PMID: 32433693.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    40. Shi B, Zhang J, Heng J, Gong J, Zhang T, Li P, Sun BF, Yang Y, Zhang N, Zhao YL, Wang HL, Liu F, Zhang QC, Yang YG. RNA structural dynamics regulate early embryogenesis through controlling transcriptome fate and function. Genome Biol. 2020 05 18; 21(1):120. PMID: 32423473.
      Citations: 23     Fields:    Translation:AnimalsCells
    41. Li X, Liang QX, Lin JR, Peng J, Yang JH, Yi C, Yu Y, Zhang QC, Zhou KR. Epitranscriptomic technologies and analyses. Sci China Life Sci. 2020 Apr; 63(4):501-515. PMID: 32170629.
      Citations: 6     Fields:    Translation:Cells
    42. Yin Y, Lu JY, Zhang X, Shao W, Xu Y, Li P, Hong Y, Cui L, Shan G, Tian B, Zhang QC, Shen X. U1 snRNP regulates chromatin retention of noncoding RNAs. Nature. 2020 04; 580(7801):147-150. PMID: 32238924.
      Citations: 89     Fields:    Translation:HumansAnimalsCells
    43. Weng X, Gong J, Chen Y, Wu T, Wang F, Yang S, Yuan Y, Luo G, Chen K, Hu L, Ma H, Wang P, Zhang QC, Zhou X, He C. Keth-seq for transcriptome-wide RNA structure mapping. Nat Chem Biol. 2020 05; 16(5):489-492. PMID: 32015521.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    44. Liu X, Wang X, Li J, Hu S, Deng Y, Yin H, Bao X, Zhang QC, Wang G, Wang B, Shi Q, Shan G. Identification of mecciRNAs and their roles in the mitochondrial entry of proteins. Sci China Life Sci. 2020 10; 63(10):1429-1449. PMID: 32048164.
      Citations: 79     Fields:    Translation:HumansAnimalsCells
    45. Kim HK, Xu J, Chu K, Park H, Jang H, Li P, Valdmanis PN, Zhang QC, Kay MA. A tRNA-Derived Small RNA Regulates Ribosomal Protein S28 Protein Levels after Translation Initiation in Humans and Mice. Cell Rep. 2019 12 17; 29(12):3816-3824.e4. PMID: 31851915.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    46. Zhang C, Guo S, Zhong Q, Zhang Q, Hossain A, Zheng S, Wang G. Metabolism and Pharmacokinetic Study of the Boron-Containing Prodrug of Belinostat (ZL277), a Pan HDAC Inhibitor with Enhanced Bioavailability. Pharmaceuticals (Basel). 2019 Dec 08; 12(4). PMID: 31817969.
      Citations:    
    47. Li P, Shi R, Zhang QC. icSHAPE-pipe: A comprehensive toolkit for icSHAPE data analysis and evaluation. Methods. 2020 06 01; 178:96-103. PMID: 31606387.
      Citations: 7     Fields:    Translation:Cells
    48. Xiong L, Xu K, Tian K, Shao Y, Tang L, Gao G, Zhang M, Jiang T, Zhang QC. SCALE method for single-cell ATAC-seq analysis via latent feature extraction. Nat Commun. 2019 10 08; 10(1):4576. PMID: 31594952.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    49. Gao Y, Pei G, Li D, Li R, Shao Y, Zhang QC, Li P. Multivalent m6A motifs promote phase separation of YTHDF proteins. Cell Res. 2019 09; 29(9):767-769. PMID: 31388144.
      Citations: 77     Fields:    Translation:Cells
    50. Sun L, Fazal FM, Li P, Broughton JP, Lee B, Tang L, Huang W, Kool ET, Chang HY, Zhang QC. RNA structure maps across mammalian cellular compartments. Nat Struct Mol Biol. 2019 04; 26(4):322-330. PMID: 30886404.
      Citations: 117     Fields:    Translation:HumansAnimalsCells
    51. Zhao J, Qian X, Yeung PY, Zhang QC, Kwok CK. Mapping In Vivo RNA Structures and Interactions. Trends Biochem Sci. 2019 06; 44(6):555-556. PMID: 30853244.
      Citations: 8     Fields:    Translation:Cells
    52. Li P, Wei Y, Mei M, Tang L, Sun L, Huang W, Zhou J, Zou C, Zhang S, Qin CF, Jiang T, Dai J, Tan X, Zhang QC. Integrative Analysis of Zika Virus Genome RNA Structure Reveals Critical Determinants of Viral Infectivity. Cell Host Microbe. 2018 12 12; 24(6):875-886.e5. PMID: 30472207.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    53. Qian X, Zhao J, Yeung PY, Zhang QC, Kwok CK. Revealing lncRNA Structures and Interactions by Sequencing-Based Approaches. Trends Biochem Sci. 2019 01; 44(1):33-52. PMID: 30459069.
      Citations: 215     Fields:    Translation:HumansCells
    54. Ju Y, Gong J, Yang YT, Zhang QC. Investigation of RNA-RNA Interactions Using the RISE Database. Curr Protoc Bioinformatics. 2018 12; 64(1):e58. PMID: 30408350.
      Citations:    Fields:    
    55. Liu Z, Wang J, Cheng H, Ke X, Sun L, Zhang QC, Wang HW. Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate. Cell. 2018 05 31; 173(6):1549-1550. PMID: 29856959.
      Citations: 15     Fields:    
    56. Liu Z, Wang J, Cheng H, Ke X, Sun L, Zhang QC, Wang HW. Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate. Cell. 2018 05 17; 173(5):1191-1203.e12. PMID: 29706542.
      Citations: 82     Fields:    Translation:HumansCells
    57. Zheng S, Guo S, Zhong Q, Zhang C, Liu J, Yang L, Zhang Q, Wang G. Biocompatible Boron-Containing Prodrugs of Belinostat for the Potential Treatment of Solid Tumors. ACS Med Chem Lett. 2018 Feb 08; 9(2):149-154. PMID: 29456804.
      Citations:    
    58. Gong J, Shao D, Xu K, Lu Z, Lu ZJ, Yang YT, Zhang QC. RISE: a database of RNA interactome from sequencing experiments. Nucleic Acids Res. 2018 01 04; 46(D1):D194-D201. PMID: 29040625.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    59. Lu Z, Gong J, Zhang QC. PARIS: Psoralen Analysis of RNA Interactions and Structures with High Throughput and Resolution. Methods Mol Biol. 2018; 1649:59-84. PMID: 29130190.
      Citations: 26     Fields:    Translation:Cells
    60. Kim HK, Fuchs G, Wang S, Wei W, Zhang Y, Park H, Roy-Chaudhuri B, Li P, Xu J, Chu K, Zhang F, Chua MS, So S, Zhang QC, Sarnow P, Kay MA. A transfer-RNA-derived small RNA regulates ribosome biogenesis. Nature. 2017 12 07; 552(7683):57-62. PMID: 29186115.
      Citations: 245     Fields:    Translation:HumansAnimalsCells
    61. Piao M, Sun L, Zhang QC. RNA Regulations and Functions Decoded by Transcriptome-wide RNA Structure Probing. Genomics Proteomics Bioinformatics. 2017 10; 15(5):267-278. PMID: 29031843.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    62. Zhang C, Guo S, Yang L, Liu J, Zheng S, Zhong Q, Zhang Q, Wang G. Metabolism, pharmacokinetics, and bioavailability of ZB716, a Steroidal Selective Estrogen Receptor Downregulator (SERD). Oncotarget. 2017 Nov 28; 8(61):103874-103889. PMID: 29262607.
      Citations: 9     Fields:    
    63. Yu KH, Hart SN, Goldfeder R, Zhang QC, Parker SCJ, Snyder M. HARNESSING BIG DATA FOR PRECISION MEDICINE: INFRASTRUCTURES AND APPLICATIONS. Pac Symp Biocomput. 2017; 22:635-639. PMID: 27897013.
      Citations:    Fields:    Translation:Humans
    64. Liu J, Zheng S, Guo S, Zhang C, Zhong Q, Zhang Q, Ma P, Skripnikova EV, Bratton MR, Wiese TE, Wang G. Rational Design of a Boron-Modified Triphenylethylene (GLL398) as an Oral Selective Estrogen Receptor Downregulator. ACS Med Chem Lett. 2017 Jan 12; 8(1):102-106. PMID: 28105283.
      Citations:    
    65. Liu J, Zheng S, Akerstrom VL, Yuan C, Ma Y, Zhong Q, Zhang C, Zhang Q, Guo S, Ma P, Skripnikova EV, Bratton MR, Pannuti A, Miele L, Wiese TE, Wang G. Fulvestrant-3 Boronic Acid (ZB716): An Orally Bioavailable Selective Estrogen Receptor Downregulator (SERD). J Med Chem. 2016 09 08; 59(17):8134-40. PMID: 27529700.
      Citations: 24     Fields:    Translation:AnimalsCells
    66. Lu Z, Zhang QC, Lee B, Flynn RA, Smith MA, Robinson JT, Davidovich C, Gooding AR, Goodrich KJ, Mattick JS, Mesirov JP, Cech TR, Chang HY. RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure. Cell. 2016 May 19; 165(5):1267-1279. PMID: 27180905.
      Citations: 304     Fields:    Translation:HumansAnimalsCells
    67. Du F, Li Y, Zhang W, Kale SP, McFerrin H, Davenport I, Wang G, Skripnikova E, Li XL, Bowen NJ, McDaniels LB, Meng YX, Polk P, Liu YY, Zhang QJ. Highly and moderately aggressive mouse ovarian cancer cell lines exhibit differential gene expression. Tumour Biol. 2016 Aug; 37(8):11147-11162. PMID: 26935058.
      Citations: 7     Fields:    Translation:AnimalsCells
    68. Quinn JJ, Zhang QC, Georgiev P, Ilik IA, Akhtar A, Chang HY. Rapid evolutionary turnover underlies conserved lncRNA-genome interactions. Genes Dev. 2016 Jan 15; 30(2):191-207. PMID: 26773003.
      Citations: 98     Fields:    Translation:AnimalsCells
    69. Flynn RA, Zhang QC, Spitale RC, Lee B, Mumbach MR, Chang HY. Transcriptome-wide interrogation of RNA secondary structure in living cells with icSHAPE. Nat Protoc. 2016 Feb; 11(2):273-90. PMID: 26766114.
      Citations: 77     Fields:    Translation:Cells
    70. Spitale RC, Flynn RA, Zhang QC, Crisalli P, Lee B, Jung JW, Kuchelmeister HY, Batista PJ, Torre EA, Kool ET, Chang HY. Erratum: Structural imprints in vivo decode RNA regulatory mechanisms. Nature. 2015 Nov 12; 527(7577):264. PMID: 26416736.
      Citations: 6     Fields:    
    71. Zhong Q, Zhang C, Zhang Q, Miele L, Zheng S, Wang G. Boronic prodrug of 4-hydroxytamoxifen is more efficacious than tamoxifen with enhanced bioavailability independent of CYP2D6 status. BMC Cancer. 2015 Sep 09; 15:625. PMID: 26354796.
      Citations: 13     Fields:    Translation:AnimalsCells
    72. Zhang C, Zhong Q, Zhang Q, Zheng S, Miele L, Wang G. Boronic prodrug of endoxifen as an effective hormone therapy for breast cancer. Breast Cancer Res Treat. 2015 Jul; 152(2):283-91. PMID: 26071758.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    73. Washington C, Maxwell J, Stevenson J, Malone G, Lowe EW, Zhang Q, Wang G, McIntyre NR. Mechanistic studies of the tyrosinase-catalyzed oxidative cyclocondensation of 2-aminophenol to 2-aminophenoxazin-3-one. Arch Biochem Biophys. 2015 Jul; 577-578:24-34. PMID: 25982123.
      Citations: 5     Fields:    Translation:AnimalsCells
    74. Chu C, Zhang QC, da Rocha ST, Flynn RA, Bharadwaj M, Calabrese JM, Magnuson T, Heard E, Chang HY. Systematic discovery of Xist RNA binding proteins. Cell. 2015 Apr 09; 161(2):404-16. PMID: 25843628.
      Citations: 530     Fields:    Translation:HumansAnimalsCells
    75. Spitale RC, Flynn RA, Zhang QC, Crisalli P, Lee B, Jung JW, Kuchelmeister HY, Batista PJ, Torre EA, Kool ET, Chang HY. Structural imprints in vivo decode RNA regulatory mechanisms. Nature. 2015 Mar 26; 519(7544):486-90. PMID: 25799993.
      Citations: 380     Fields:    Translation:AnimalsCells
    76. Li XL, Sluijter M, Doorduijn EM, Kale SP, McFerrin H, Liu YY, Li Y, Mottamal M, Yao X, Du F, Gu B, Hoang K, Nguyen YH, Taylor N, Stephens CR, van Hall T, Zhang QJ. Limited density of an antigen presented by RMA-S cells requires B7-1/CD28 signaling to enhance T-cell immunity at the effector phase. PLoS One. 2014; 9(11):e108192. PMID: 25383875.
      Citations: 1     Fields:    Translation:AnimalsCells
    77. Zheng S, Zhong Q, Xi Y, Mottamal M, Zhang Q, Schroeder RL, Sridhar J, He L, McFerrin H, Wang G. Modification and biological evaluation of thiazole derivatives as novel inhibitors of metastatic cancer cell migration and invasion. J Med Chem. 2014 Aug 14; 57(15):6653-67. PMID: 25007006.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    78. Deng L, Zhang QC, Chen Z, Meng Y, Guan J, Zhou S. PredHS: a web server for predicting protein-protein interaction hot spots by using structural neighborhood properties. Nucleic Acids Res. 2014 Jul; 42(Web Server issue):W290-5. PMID: 24852252.
      Citations: 24     Fields:    Translation:Cells
    79. Zheng S, Zhong Q, Mottamal M, Zhang Q, Zhang C, Lemelle E, McFerrin H, Wang G. Design, synthesis, and biological evaluation of novel pyridine-bridged analogues of combretastatin-A4 as anticancer agents. J Med Chem. 2014 Apr 24; 57(8):3369-81. PMID: 24669888.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    80. Wan Y, Qu K, Zhang QC, Flynn RA, Manor O, Ouyang Z, Zhang J, Spitale RC, Snyder MP, Segal E, Chang HY. Landscape and variation of RNA secondary structure across the human transcriptome. Nature. 2014 Jan 30; 505(7485):706-9. PMID: 24476892.
      Citations: 298     Fields:    Translation:HumansCells
    81. Deng L, Guan J, Wei X, Yi Y, Zhang QC, Zhou S. Boosting prediction performance of protein-protein interaction hot spots by using structural neighborhood properties. J Comput Biol. 2013 Nov; 20(11):878-91. PMID: 24134392.
      Citations: 20     Fields:    Translation:Cells
    82. Kasowski M, Kyriazopoulou-Panagiotopoulou S, Grubert F, Zaugg JB, Kundaje A, Liu Y, Boyle AP, Zhang QC, Zakharia F, Spacek DV, Li J, Xie D, Olarerin-George A, Steinmetz LM, Hogenesch JB, Kellis M, Batzoglou S, Snyder M. Extensive variation in chromatin states across humans. Science. 2013 Nov 08; 342(6159):750-2. PMID: 24136358.
      Citations: 199     Fields:    Translation:HumansCells
    83. Tilghman SL, Townley I, Zhong Q, Carriere PP, Zou J, Llopis SD, Preyan LC, Williams CC, Skripnikova E, Bratton MR, Zhang Q, Wang G. Proteomic signatures of acquired letrozole resistance in breast cancer: suppressed estrogen signaling and increased cell motility and invasiveness. Mol Cell Proteomics. 2013 Sep; 12(9):2440-55. PMID: 23704778.
      Citations: 36     Fields:    Translation:HumansCells
    84. Zheng S, Zhong Q, Jiang Q, Mottamal M, Zhang Q, Zhu N, Burow ME, Worthylake RA, Wang G. Discovery of a Series of Thiazole Derivatives as Novel Inhibitors of Metastatic Cancer Cell Migration and Invasion. ACS Med Chem Lett. 2013 Feb 14; 4(2):191-196. PMID: 23526571.
      Citations:    
    85. Zhang QC, Petrey D, Garz?n JI, Deng L, Honig B. PrePPI: a structure-informed database of protein-protein interactions. Nucleic Acids Res. 2013 01; 41(Database issue):D828-33. PMID: 23193263.
      Citations: 103     Fields:    Translation:HumansCells
    86. Zhang QC, Petrey D, Deng L, Qiang L, Shi Y, Thu CA, Bisikirska B, Lefebvre C, Accili D, Hunter T, Maniatis T, Califano A, Honig B. Structure-based prediction of protein-protein interactions on a genome-wide scale. Nature. 2012 Oct 25; 490(7421):556-60. PMID: 23023127.
      Citations: 293     Fields:    Translation:HumansAnimalsCells
    87. Jiang Q, Zhong Q, Zhang Q, Zheng S, Wang G. Boron-Based 4-Hydroxytamoxifen Bioisosteres for Treatment of de Novo Tamoxifen Resistant Breast Cancer. ACS Med Chem Lett. 2012 Apr 06; 3(5):392-396. PMID: 23864928.
      Citations:    
    88. Wang G, Ma P, Zhang Q, Lewis J, Lacey M, Furukawa Y, O'Reilly SE, Meaux S, McLachlan J, Zhang S. Endocrine disrupting chemicals in New Orleans surface waters and Mississippi Sound sediments. J Environ Monit. 2012 May; 14(5):1353-64. PMID: 22438038.
      Citations: 6     Fields:    Translation:PHPublic Health
    89. Zhou C, Zhong Q, Rhodes LV, Townley I, Bratton MR, Zhang Q, Martin EC, Elliott S, Collins-Burow BM, Burow ME, Wang G. Proteomic analysis of acquired tamoxifen resistance in MCF-7 cells reveals expression signatures associated with enhanced migration. Breast Cancer Res. 2012 Mar 14; 14(2):R45. PMID: 22417809.
      Citations: 68     Fields:    Translation:HumansCells
    90. Eletsky A, Petrey D, Zhang QC, Lee HW, Acton TB, Xiao R, Everett JK, Prestegard JH, Honig B, Montelione GT, Szyperski T. Solution NMR structures reveal unique homodimer formation by a winged helix-turn-helix motif and provide first structures for protein domain family PF10771. J Struct Funct Genomics. 2012 Mar; 13(1):1-7. PMID: 22223187.
      Citations: 1     Fields:    Translation:Cells
    91. Fischer M, Zhang QC, Dey F, Chen BY, Honig B, Petrey D. MarkUs: a server to navigate sequence-structure-function space. Nucleic Acids Res. 2011 Jul; 39(Web Server issue):W357-61. PMID: 21672961.
      Citations: 12     Fields:    Translation:Cells
    92. Zhang QC, Deng L, Fisher M, Guan J, Honig B, Petrey D. PredUs: a web server for predicting protein interfaces using structural neighbors. Nucleic Acids Res. 2011 Jul; 39(Web Server issue):W283-7. PMID: 21609948.
      Citations: 48     Fields:    Translation:Cells
    93. Jiang Q, Payton-Stewart F, Elliott S, Driver J, Rhodes LV, Zhang Q, Zheng S, Bhatnagar D, Boue SM, Collins-Burow BM, Sridhar J, Stevens C, McLachlan JA, Wiese TE, Burow ME, Wang G. Effects of 7-O substitutions on estrogenic and anti-estrogenic activities of daidzein analogues in MCF-7 breast cancer cells. J Med Chem. 2010 Aug 26; 53(16):6153-63. PMID: 20669983.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    94. Zhang Q, Ma P, Cole RB, Wang G. In vitro metabolism of indomethacin morpholinylamide (BML-190), an inverse agonist for the peripheral cannabinoid receptor (CB(2)) in rat liver microsomes. Eur J Pharm Sci. 2010 Sep 11; 41(1):163-72. PMID: 20542112.
      Citations: 1     Fields:    Translation:AnimalsCells
    95. Zhang QC, Petrey D, Norel R, Honig BH. Protein interface conservation across structure space. Proc Natl Acad Sci U S A. 2010 Jun 15; 107(24):10896-901. PMID: 20534496.
      Citations: 74     Fields:    Translation:Cells
    96. Zhou C, Nitschke AM, Xiong W, Zhang Q, Tang Y, Bloch M, Elliott S, Zhu Y, Bazzone L, Yu D, Weldon CB, Schiff R, McLachlan JA, Beckman BS, Wiese TE, Nephew KP, Shan B, Burow ME, Wang G. Proteomic analysis of tumor necrosis factor-alpha resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype. Breast Cancer Res. 2008; 10(6):R105. PMID: 19087274.
      Citations: 61     Fields:    Translation:Humans
    97. Huang TL, Bacchi CJ, Kode NR, Zhang Q, Wang G, Yartlet N, Rattendi D, Londono I, Mazumder L, Vanden Eynde JJ, Mayence A, Donkor IO. Trypanocidal activity of piperazine-linked bisbenzamidines and bisbenzamidoxime, an orally active prodrug. Int J Antimicrob Agents. 2007 Dec; 30(6):555-61. PMID: 17920820.
      Citations: 6     Fields:    Translation:HumansAnimals
    98. Zhang Q, Ma P, Cole RB, Wang G. Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MS. Anal Bioanal Chem. 2006 Nov; 386(5):1345-55. PMID: 16955257.
      Citations: 12     Fields:    Translation:Cells
    99. Zhang Q, Ma P, Wang W, Cole RB, Wang G. In vitro metabolism of diarylpyrazoles, a novel group of cannabinoid receptor ligands. Drug Metab Dispos. 2005 Apr; 33(4):508-17. PMID: 15616153.
      Citations: 3     Fields:    Translation:AnimalsCells
    100. Zhang Q, Ma P, Wang W, Cole RB, Wang G. Characterization of rat liver microsomal metabolites of AM-630, a potent cannabinoid receptor antagonist, by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry. J Mass Spectrom. 2004 Jun; 39(6):672-81. PMID: 15236306.
      Citations: 7     Fields:    Translation:AnimalsCells
    101. Zhang Q, Ma P, Iszard M, Cole RB, Wang W, Wang G. In vitro metabolism of R(+)-[2,3-dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo [1,2,3-de]1,4-benzoxazinyl]-(1-naphthalenyl) methanone mesylate, a cannabinoid receptor agonist. Drug Metab Dispos. 2002 Oct; 30(10):1077-86. PMID: 12228183.
      Citations: 9     Fields:    Translation:AnimalsCells
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