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Michael J Gonzalez

Faculty RankProfessor
InstitutionUniversity of Puerto Rico
DepartmentSchool of Public Health
AddressUPR-Medical Sciences Campus
Deptarment Human Development, Nutrition Program
San Juan PR 936
Phone7877582525 e 1405
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    Other Positions
    TitleAdjunct Professor
    InstitutionUniversity of Western States
    DepartmentHuman Nutrition and Functional Medicine

    TitleAdjunct Professor
    InstitutionEDP University
    DepartmentNaturopathic Sciences

    Collapse Overview 
    Collapse overview
    Dr. Michael J. Gonzalez is Professor at the Nutrition Program, School of Public Health in the Medical Sciences Campus, University of Puerto Rico and Adjunct faculty at the University of Western States. He earned a Bachelor Degree in Biology and Chemistry (Catholic University), a Masters in Cellular Biology and Biophysics (Nova University), and another Masters in Nutrition and Public Health (University of PR Med Sciences Campus). He has a Doctorate in Nutritional Medicine (John F. Kennedy University). He also has a Doctorate in Health Sciences (Lafayette University), and another Doctorate in Nutritional Biochemistry and Cancer Biology (Michigan State University). He completed a Post-Doctoral Fellowship in Geriatrics at the School of Medicine, University of Puerto Rico. Dr. Gonzalez is a Fellow of the American College of Nutrition, and has authored over 150 scientific publications. He has serve as a member on several scientific journal Editorial Boards, such as Biomedicina, the Journal of Orthomolecular Medicine, and Alternative Medicine Reviews. He has served as consultant for several companies, he has been responsible for designing formulations of nutritional supplements and pharmaceutical products. He has also been a consultant for The Center for the Improvement of Human Functioning (now Riordan Clinic), in Wichita, Kansas. He has obtained several research awards for his work on Nutrition and Cancer. He is currently Co- Director of RECNAC II project, and Research Director of the InBioMed Project Initiative. Dr. Gonzalez also serves as a nutrition consultant to the Puerto Rican Basketball National Team and is part of the Medical Commission of the Puerto Rican Basketball Federation. He is in a part time clinical practice with Dr. Miguel J Berdiel in Ponce, PR. In December 2013,Dr Gonzalez was exalted as Distinguished Ponceño in Medicine.

    Doctor González and Dr. Jorge Miranda-Massari, founders of InBioMed, are leaders in the development of non-toxic chemotherapy treatments for cancer. The findings of their work with Intravenous Vitamin C as an anti-cancer agent, published in 2002, were confirmed by the NIH in 2005. They published the first Phase-I clinical study utilizing Intravenous Vitamin C for treatment of terminal cancer patients in 2005, and also published in 2005 the most comprehensive review on Vitamin C and Cancer, as a follow-up on the work of two times Nobel Laureate, Dr. Linus C. Pauling. They have brought many new concepts into the scientific field, such as the Bioenergetic theory of carcinogenesis, the systemic saturation phenomenon of intravenous vitamin C, the metabolic correction concept for disease treatment and prevention. Currently they are finishing a book on Vitamin C and Cancer for Springer-Larger.

    Book: Doctors Gonzalez, Miranda-Massari and Saul’s book “I Have Cancer What Should I do: The Orthomolecular Guide to Cancer Management” provides evidence based recommendations for an integrative approach for those dealing with cancer and seeking to improve quality of life and survival.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Takkellapati S, Gonzalez MA. Application of read-across methods as a framework for the estimation of emissions from chemical processes. Clean Technol Recycl. 2023 Dec 28; 3(4):283-300. PMID: 38357098.
    2. Barrett WM, Meyer DE, Smith RL, Takkellapati S, Gonzalez MA. Review of generic scenario environmental release and occupational exposure models used in chemical risk assessment. J Occup Environ Hyg. 2023 11; 20(11):545-562. PMID: 37526475.
      Citations:    Fields:    Translation:HumansPHPublic Health
    3. Smith RL, Terriquez J, Thoma E, Gonzalez MA, Johnson D, Buenning H, Kremer F, Carpenter JD, Clark NN. Climate Change, Extreme Events, and Their Potential Effects on Aboveground Storage Tanks. EM (Pittsburgh Pa). 2023 Sep; 2023. PMID: 38268967.
    4. Miranda-Massari JR, Toro AP, Loh D, Rodriguez JR, Borges RM, Marcial-Vega V, Olalde J, Berdiel MJ, Riordan NH, Martinez JM, Gil A, Gonzalez MJ. The Effects of Vitamin C on the Multiple Pathophysiological Stages of COVID-19. Life (Basel). 2021 Dec 03; 11(12). PMID: 34947872.
    5. Gonzalez MJ, Kweh MF, Biava PM, Olalde J, Toro AP, Goldschmidt-Clermont PJ, White IA. Evaluation of exosome derivatives as bio-informational reprogramming therapy for cancer. J Transl Med. 2021 03 09; 19(1):103. PMID: 33750417.
      Citations: 5     Fields:    Translation:HumansCells
    6. van der Zande HJP, Gonzalez MA, de Ruiter K, Wilbers RHP, Garc?a-Tard?n N, van Huizen M, van Noort K, Pelgrom LR, Lambooij JM, Zawistowska-Deniziak A, Otto F, Ozir-Fazalalikhan A, van Willigen D, Welling M, Poles J, van Leeuwen F, Hokke CH, Schots A, Yazdanbakhsh M, Loke P, Guigas B. The helminth glycoprotein omega-1 improves metabolic homeostasis in obese mice through type 2 immunity-independent inhibition of food intake. FASEB J. 2021 02; 35(2):e21331. PMID: 33476078.
      Citations: 16     Fields:    Translation:AnimalsCells
    7. Chan Wah Hak C, Coyle C, Kocache A, Short D, Sarwar N, Seckl MJ, Gonzalez MA. Emergency Etoposide-Cisplatin (Em-EP) for patients with germ cell tumours (GCT) and trophoblastic neoplasia (TN). BMC Cancer. 2019 Aug 05; 19(1):770. PMID: 31382912.
      Citations: 3     Fields:    Translation:Humans
    8. Barrett WM, Takkellapati S, Tadele K, Martin TM, Gonzalez MA. Linking Molecular Structure via Functional Group to Chemical Literature for Establishing a Reaction Lineage for Application to Alternatives Assessment. ACS Sustain Chem Eng. 2019 Apr 15; 7(8):7630-7641. PMID: 33123418.
    9. Gonzalez MA, Takkellapati S, Tadele K, Li T, Varma RS. Framework towards more Sustainable Chemical Synthesis Design - A Case Study of Organophosphates. ACS Sustain Chem Eng. 2019 Feb 25; 7(7):6744-6757. PMID: 32280570.
    10. Wu C, Devkota B, Evans P, Zhao X, Baker SW, Niazi R, Cao K, Gonzalez MA, Jayaraman P, Conlin LK, Krock BL, Deardorff MA, Spinner NB, Krantz ID, Santani AB, Tayoun ANA, Sarmady M. Rapid and accurate interpretation of clinical exomes using Phenoxome: a computational phenotype-driven approach. Eur J Hum Genet. 2019 04; 27(4):612-620. PMID: 30626929.
      Citations: 9     Fields:    Translation:Humans
    11. Meyer DE, Mittal VK, Ingwersen WW, Ruiz-Mercado GJ, Barrett WM, Gonzalez MA, Abraham JP, Smith RL. Purpose-Driven Reconciliation of Approaches to Estimate Chemical Releases. ACS Sustain Chem Eng. 2019 Jan 07; 7:1260-1270. PMID: 30881772.
    12. Takkellapati S, Li T, Gonzalez MA. An Overview of Biorefinery Derived Platform Chemicals from a Cellulose and Hemicellulose Biorefinery. Clean Technol Environ Policy. 2018 Sep; 20(7):1615-1630. PMID: 30319323.
    13. Mittal VK, Bailin SC, Gonzalez MA, Meyer DE, Barrett WM, Smith RL. Toward Automated Inventory Modeling in Life Cycle Assessment: The Utility of Semantic Data Modeling to Predict Real-World Chemical Production. ACS Sustain Chem Eng. 2017 Dec 06; 6(2):1961-1976. PMID: 32632354.
    14. Gundra UM, Girgis NM, Gonzalez MA, San Tang M, Van Der Zande HJP, Lin JD, Ouimet M, Ma LJ, Poles J, Vozhilla N, Fisher EA, Moore KJ, Loke P. Vitamin A mediates conversion of monocyte-derived macrophages into tissue-resident macrophages during alternative activation. Nat Immunol. 2017 06; 18(6):642-653. PMID: 28436955.
      Citations: 73     Fields:    Translation:AnimalsCells
    15. Tadele K, Verma S, Gonzalez MA, Varma RS. A sustainable approach to empower the bio-based future: upgrading of biomass via process intensification. Green Chem. 2017; 19(7):1624-1627. PMID: 30294242.
    16. Smith RL, Ruiz-Mercado GJ, Meyer DE, Gonzalez MA, Abraham JP, Barrett WM, Randall PM. Coupling Computer-Aided Process Simulation and Estimations of Emissions and Land Use for Rapid Life Cycle Inventory Modeling. ACS Sustain Chem Eng. 2017; 5(5):3786-3794. PMID: 30245942.
    17. Horga A, Tomaselli PJ, Gonzalez MA, Laur? M, Muntoni F, Manzur AY, Hanna MG, Blake JC, Houlden H, Z?chner S, Reilly MM. SIGMAR1 mutation associated with autosomal recessive Silver-like syndrome. Neurology. 2016 Oct 11; 87(15):1607-1612. PMID: 27629094.
      Citations: 17     Fields:    Translation:Humans
    18. Pottier C, Ravenscroft TA, Brown PH, Finch NA, Baker M, Parsons M, Asmann YW, Ren Y, Christopher E, Levitch D, van Blitterswijk M, Cruchaga C, Campion D, Nicolas G, Richard AC, Guerreiro R, Bras JT, Zuchner S, Gonzalez MA, Bu G, Younkin S, Knopman DS, Josephs KA, Parisi JE, Petersen RC, Ertekin-Taner N, Graff-Radford NR, Boeve BF, Dickson DW, Rademakers R. TYROBP genetic variants in early-onset Alzheimer's disease. Neurobiol Aging. 2016 12; 48:222.e9-222.e15. PMID: 27658901.
      Citations: 39     Fields:    Translation:HumansCells
    19. Vaddula BR, Tantak MP, Sadana R, Gonzalez MA, Kumar D. One-pot synthesis and in-vitro anticancer evaluation of 5-(2'-indolyl)thiazoles. Sci Rep. 2016 Mar 29; 6:23401. PMID: 27021742.
      Citations: 3     Fields:    Translation:HumansCells
    20. Balicza P, Grosz Z, Gonzalez MA, Bencsik R, Pentelenyi K, Gal A, Varga E, Klivenyi P, Koller J, Z?chner S, Molnar JM. Genetic background of the hereditary spastic paraplegia phenotypes in Hungary - An analysis of 58 probands. J Neurol Sci. 2016 May 15; 364:116-21. PMID: 27084228.
      Citations: 14     Fields:    Translation:Humans
    21. Gonzalez MJ, Berdiel MJ, Miranda-Massari JR, Duconge J, Rodr?guez-L?pez JL, Adrover-L?pez PA. High Dose Intravenous Vitamin C Treatment for Zika Fever. J Orthomol Med. 2016; 31(1):19-22. PMID: 36177383.
    22. Hickey S, Schuitemaker G, Yanagisawa A, Noriega L, Gonz?lez MJ, Miranda-Massari JR, Chibelushi C, Downing D. Archaic RDA Methodology for Vitamin C. Crit Rev Food Sci Nutr. 2015 Oct 29. PMID: 26513263.
      Citations: 1     Fields:    
    23. Strickland AV, Schabh?ttl M, Offenbacher H, Synofzik M, Hauser NS, Brunner-Krainz M, Gruber-Sedlmayr U, Moore SA, Windhager R, Bender B, Harms M, Klebe S, Young P, Kennerson M, Garcia AS, Gonzalez MA, Z?chner S, Schule R, Shy ME, Auer-Grumbach M. Mutation screen reveals novel variants and expands the phenotypes associated with DYNC1H1. J Neurol. 2015 Sep; 262(9):2124-34. PMID: 26100331.
      Citations: 24     Fields:    Translation:HumansCells
    24. Goodson WH, Lowe L, Carpenter DO, Gilbertson M, Manaf Ali A, Lopez de Cerain Salsamendi A, Lasfar A, Carnero A, Azqueta A, Amedei A, Charles AK, Collins AR, Ward A, Salzberg AC, Colacci A, Olsen AK, Berg A, Barclay BJ, Zhou BP, Blanco-Aparicio C, Baglole CJ, Dong C, Mondello C, Hsu CW, Naus CC, Yedjou C, Curran CS, Laird DW, Koch DC, Carlin DJ, Felsher DW, Roy D, Brown DG, Ratovitski E, Ryan EP, Corsini E, Rojas E, Moon EY, Laconi E, Marongiu F, Al-Mulla F, Chiaradonna F, Darroudi F, Martin FL, Van Schooten FJ, Goldberg GS, Wagemaker G, Nangami GN, Calaf GM, Williams G, Wolf GT, Koppen G, Brunborg G, Lyerly HK, Krishnan H, Ab Hamid H, Yasaei H, Sone H, Kondoh H, Salem HK, Hsu HY, Park HH, Koturbash I, Miousse IR, Scovassi AI, Klaunig JE, Vondr?cek J, Raju J, Roman J, Wise JP, Whitfield JR, Woodrick J, Christopher JA, Ochieng J, Martinez-Leal JF, Weisz J, Kravchenko J, Sun J, Prudhomme KR, Narayanan KB, Cohen-Solal KA, Moorwood K, Gonzalez L, Soucek L, Jian L, D'Abronzo LS, Lin LT, Li L, Gulliver L, McCawley LJ, Memeo L, Vermeulen L, Leyns L, Zhang L, Valverde M, Khatami M, Romano MF, Chapellier M, Williams MA, Wade M, Manjili MH, Lleonart ME, Xia M, Gonzalez MJ, Karamouzis MV, Kirsch-Volders M, Vaccari M, Kuemmerle NB, Singh N, Cruickshanks N, Kleinstreuer N, van Larebeke N, Ahmed N, Ogunkua O, Krishnakumar PK, Vadgama P, Marignani PA, Ghosh PM, Ostrosky-Wegman P, Thompson PA, Dent P, Heneberg P, Darbre P, Sing Leung P, Nangia-Makker P, Cheng QS, Robey RB, Al-Temaimi R, Roy R, Andrade-Vieira R, Sinha RK, Mehta R, Vento R, Di Fiore R, Ponce-Cusi R, Dornetshuber-Fleiss R, Nahta R, Castellino RC, Palorini R, Abd Hamid R, Langie SA, Eltom SE, Brooks SA, Ryeom S, Wise SS, Bay SN, Harris SA, Papagerakis S, Romano S, Pavanello S, Eriksson S, Forte S, Casey SC, Luanpitpong S, Lee TJ, Otsuki T, Chen T, Massfelder T, Sanderson T, Guarnieri T, Hultman T, Dormoy V, Odero-Marah V, Sabbisetti V, Maguer-Satta V, Rathmell WK, Engstr?m W, Decker WK, Bisson WH, Rojanasakul Y, Luqmani Y, Chen Z, Hu Z. Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. Carcinogenesis. 2015 Jun; 36 Suppl 1:S254-96. PMID: 26106142.
      Citations: 85     Fields:    Translation:HumansAnimalsPHPublic Health
    25. Miranda-Massari JR, Gonz?lez MJ, Rodriguez-Gomez JR, Duconge J, Allende-Vigo MZ, Jim?nez Ramirez FJ, Cintr?n K, Ricart C, Zaragoza-Urdaz R, Berdiel MJ, V?zquez A. [Metabolic correction: a biochemical option against diseases]. Bol Asoc Med P R. 2015 Apr-Jun; 107(2):60-6. PMID: 26434086.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    26. Miranda-Massari JR, Gonzalez MJ, Fernando AS, Cidre C, Paz IM, Charvel J, Mart?nez V, Duconge J, Aponte A, Ricart CM. Metabolic Correction as a tool to improve diabetes type 2 management. Bol Asoc Med P R. 2015 Apr-Jun; 107(2):54-9. PMID: 26434085.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    27. Gonz?lez MJ, Miranda-Massari JR, Duconge J, Allende-Vigo MZ, Jim?nez-Ram?rez FJ, Cintr?n K, Rodr?guez-G?mez JR, Rosario G, Ricart C, Santiago-Cornier JA, Zaragoza-Urdaz R, V?zquez A, Hickey S, Jabbar-Berdiel M, Riordan N, Ichim T, Santiago O, Alvarado G, Vora P. Metabolic correction: a functional biochemical mechanism against disease--Part 1: concept and historical background. P R Health Sci J. 2015 Mar; 34(1):3-8. PMID: 25856870.
      Citations: 1     Fields:    Translation:Humans
    28. Miranda-Massari JR, Gonz?lez MJ, Duconge J, Allende-Vigo MZ, Jim?nez-Ram?rez FJ, Hickey S, V?zquez A, Berdiel MJ, Cintr?n K, Rodr?guez-G?mez JR. Metabolic correction: a functional biochemical mechanism against disease--Part 2: mechanisms and benefits. P R Health Sci J. 2015 Mar; 34(1):9-13. PMID: 25856871.
      Citations: 1     Fields:    Translation:Humans
    29. Griffin LB, Sakaguchi R, McGuigan D, Gonzalez MA, Searby C, Z?chner S, Hou YM, Antonellis A. Impaired function is a common feature of neuropathy-associated glycyl-tRNA synthetase mutations. Hum Mutat. 2014 Nov; 35(11):1363-71. PMID: 25168514.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    30. Gonzalez MJ, Miranda-Massari JR. Diet and stress. Psychiatr Clin North Am. 2014 Dec; 37(4):579-89. PMID: 25455067.
      Citations: 10     Fields:    Translation:HumansAnimals
    31. Gonzalez MA, Feely SM, Speziani F, Strickland AV, Danzi M, Bacon C, Lee Y, Chou TF, Blanton SH, Weihl CC, Zuchner S, Shy ME. A novel mutation in VCP causes Charcot-Marie-Tooth Type 2 disease. Brain. 2014 Nov; 137(Pt 11):2897-902. PMID: 25125609.
      Citations: 55     Fields:    Translation:Humans
    32. Bonifert T, Karle KN, Tonagel F, Batra M, Wilhelm C, Theurer Y, Schoenfeld C, Kluba T, Kamenisch Y, Carelli V, Wolf J, Gonzalez MA, Speziani F, Sch?le R, Z?chner S, Sch?ls L, Wissinger B, Synofzik M. Pure and syndromic optic atrophy explained by deep intronic OPA1 mutations and an intralocus modifier. Brain. 2014 Aug; 137(Pt 8):2164-77. PMID: 24970096.
      Citations: 36     Fields:    Translation:Humans
    33. Caballero Oteyza A, Battaloglu E, Ocek L, Lindig T, Reichbauer J, Rebelo AP, Gonzalez MA, Zorlu Y, Ozes B, Timmann D, Bender B, Woehlke G, Z?chner S, Sch?ls L, Sch?le R. Motor protein mutations cause a new form of hereditary spastic paraplegia. Neurology. 2014 Jun 03; 82(22):2007-16. PMID: 24808017.
      Citations: 26     Fields:    Translation:HumansCells
    34. Gonzalez MJ, Miranda-Massari JR, Berdiel MJ, Duconge J, Rodr?guez-L?pez JL, Hunninghake R, Cobas-Rosario VJ. High Dose Intraveneous Vitamin C and Chikungunya Fever: A Case Report. J Orthomol Med. 2014; 29(4):154-156. PMID: 25705076.
    35. Dolzhanskaya N, Gonzalez MA, Sperziani F, Stefl S, Messing J, Wen GY, Alexov E, Zuchner S, Velinov M. A novel p.Leu(381)Phe mutation in presenilin 1 is associated with very early onset and unusually fast progressing dementia as well as lysosomal inclusions typically seen in Kufs disease. J Alzheimers Dis. 2014; 39(1):23-7. PMID: 24121961.
      Citations: 12     Fields:    Translation:HumansCells
    36. Foley AR, Menezes MP, Pandraud A, Gonzalez MA, Al-Odaib A, Abrams AJ, Sugano K, Yonezawa A, Manzur AY, Burns J, Hughes I, McCullagh BG, Jungbluth H, Lim MJ, Lin JP, Megarbane A, Urtizberea JA, Shah AH, Antony J, Webster R, Broomfield A, Ng J, Mathew AA, O'Byrne JJ, Forman E, Scoto M, Prasad M, O'Brien K, Olpin S, Oppenheim M, Hargreaves I, Land JM, Wang MX, Carpenter K, Horvath R, Straub V, Lek M, Gold W, Farrell MO, Brandner S, Phadke R, Matsubara K, McGarvey ML, Scherer SS, Baxter PS, King MD, Clayton P, Rahman S, Reilly MM, Ouvrier RA, Christodoulou J, Z?chner S, Muntoni F, Houlden H. Treatable childhood neuronopathy caused by mutations in riboflavin transporter RFVT2. Brain. 2014 Jan; 137(Pt 1):44-56. PMID: 24253200.
      Citations: 55     Fields:    Translation:Humans
    37. Mateo J, Ong M, Tan DS, Gonzalez MA, de Bono JS. Appraising iniparib, the PARP inhibitor that never was--what must we learn? Nat Rev Clin Oncol. 2013 Dec; 10(12):688-96. PMID: 24129347.
      Citations: 38     Fields:    Translation:Humans
    38. Betancourt J, R?os JL, Pag?n I, Fabi?n C, Gonz?lez AM, Cruz SY, Gonz?lez MJ, Rivera WT, Palacios C. Non-medical use of prescription drugs and its association with socio-demographic characteristics, dietary pattern, and perceived academic load and stress in college students in Puerto Rico. P R Health Sci J. 2013 Jun; 32(2):89-94. PMID: 23781625.
      Citations: 3     Fields:    Translation:Humans
    39. R?os JL, Betancourt J, Pag?n I, Fabi?n C, Cruz SY, Gonz?lez AM, Gonz?lez MJ, Rivera-Soto WT, Palacios C. Caffeinated-beverage consumption and its association with socio-demographic characteristics and self-perceived academic stress in first and second year students at the University of Puerto Rico Medical Sciences Campus (UPR-MSC). P R Health Sci J. 2013 Jun; 32(2):95-100. PMID: 23781626.
      Citations: 9     Fields:    Translation:HumansAnimals
    40. Gonz?lez AM, Cruz SY, R?os JL, Pag?n I, Fabi?n C, Betancourt J, Rivera-Soto WT, Gonz?lez MJ, Palacios C. Alcohol consumption and smoking and their associations with socio-demographic characteristics, dietary patterns, and perceived academic stress in Puerto Rican college students. P R Health Sci J. 2013 Jun; 32(2):82-8. PMID: 23781624.
      Citations: 6     Fields:    Translation:Humans
    41. Gonzalez MA, Lebrigio RF, Van Booven D, Ulloa RH, Powell E, Speziani F, Tekin M, Sch?le R, Z?chner S. GEnomes Management Application (GEM.app): a new software tool for large-scale collaborative genome analysis. Hum Mutat. 2013 Jun; 34(6):842-6. PMID: 23463597.
      Citations: 58     Fields:    Translation:Humans
    42. Fabi?n C, Pag?n I, R?os JL, Betancourt J, Cruz SY, Gonz?lez AM, Palacios C, Gonz?lez MJ, Rivera-Soto WT. Dietary patterns and their association with sociodemographic characteristics and perceived academic stress of college students in Puerto Rico. P R Health Sci J. 2013 Mar; 32(1):36-43. PMID: 23556264.
      Citations: 18     Fields:    Translation:Humans
    43. Cruz SY, Fabi?n C, Pag?n I, R?os JL, Gonz?lez AM, Betancourt J, Gonz?lez MJ, Rivera-Soto WT, Palacios C. Physical activity and its associations with sociodemographic characteristics, dietary patterns, and perceived academic stress in students attending college in Puerto Rico. P R Health Sci J. 2013 Mar; 32(1):44-50. PMID: 23556265.
      Citations: 11     Fields:    Translation:Humans
    44. Martin E, Sch?le R, Smets K, Rastetter A, Boukhris A, Loureiro JL, Gonzalez MA, Mundwiller E, Deconinck T, Wessner M, Jornea L, Oteyza AC, Durr A, Martin JJ, Sch?ls L, Mhiri C, Lamari F, Z?chner S, De Jonghe P, Kabashi E, Brice A, Stevanin G. Loss of function of glucocerebrosidase GBA2 is responsible for motor neuron defects in hereditary spastic paraplegia. Am J Hum Genet. 2013 Feb 07; 92(2):238-44. PMID: 23332916.
      Citations: 86     Fields:    Translation:HumansAnimalsCells
    45. Gonzalez MA, Van Booven D, Hulme W, Ulloa RH, Lebrigio RF, Osterloh J, Logan M, Freeman M, Zuchner S. Whole Genome Sequencing and a New Bioinformatics Platform Allow for Rapid Gene Identification in D. melanogaster EMS Screens. Biology (Basel). 2012 Dec 05; 1(3):766-77. PMID: 24832518.
    46. Gonzalez MJ, Miranda Massari JR, Duconge J, Riordan NH, Ichim T, Quintero-Del-Rio AI, Ortiz N. The bio-energetic theory of carcinogenesis. Med Hypotheses. 2012 Oct; 79(4):433-9. PMID: 22809841.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    47. Gonzalez MJ, Miranda Massari JR, Duconge J, Riordan NH, Ichim T. Schedule Dependence in Cancer Therapy: Intravenous Vitamin C and the Systemic Saturation Hypothesis. J Orthomol Med. 2012 Jan 01; 27(1):9-12. PMID: 24860238.
    48. Miranda-Massari JR, Gonzalez MJ, Jimenez FJ, Allende-Vigo MZ, Duconge J. Metabolic correction in the management of diabetic peripheral neuropathy: improving clinical results beyond symptom control. Curr Clin Pharmacol. 2011 Nov; 6(4):260-73. PMID: 22082324.
      Citations: 21     Fields:    Translation:Humans
    49. Ichim TE, Minev B, Braciak T, Luna B, Hunninghake R, Mikirova NA, Jackson JA, Gonzalez MJ, Miranda-Massari JR, Alexandrescu DT, Dasanu CA, Bogin V, Ancans J, Stevens RB, Markosian B, Koropatnick J, Chen CS, Riordan NH. Intravenous ascorbic acid to prevent and treat cancer-associated sepsis? J Transl Med. 2011 Mar 04; 9:25. PMID: 21375761.
      Citations: 9     Fields:    Translation:Humans
    50. Gonz?lez MJ, Miranda-Massari JR, Duconge J. Vitamin C and cancer: what can we conclude--1,609 patients and 33 years later: comment on the article by Cabanillas. P R Health Sci J. 2010 Dec; 29(4):410-1; author reply 411-2. PMID: 21261184.
      Citations:    Fields:    Translation:Humans
    51. Gonz?lez MJ, Rosario-P?rez G, Guzm?n AM, Miranda-Massari JR, Duconge J, Lavergne J, Fernandez N, Ortiz N, Quintero A, Mikirova N, Riordan NH, Ricart CM. Mitochondria, Energy and Cancer: The Relationship with Ascorbic Acid. J Orthomol Med. 2010; 25(1):29-38. PMID: 23565030.
    52. Meyer DE, Curran MA, Gonzalez MA. An examination of existing data for the industrial manufacture and use of nanocomponents and their role in the life cycle impact of nanoproducts. Environ Sci Technol. 2009 Mar 01; 43(5):1256-63. PMID: 19350888.
      Citations: 9     Fields:    
    53. Duconge J, Miranda-Massari JR, Gonzalez MJ, Jackson JA, Warnock W, Riordan NH. Pharmacokinetics of vitamin C: insights into the oral and intravenous administration of ascorbate. P R Health Sci J. 2008 Mar; 27(1):7-19. PMID: 18450228.
      Citations: 39     Fields:    Translation:Humans
    54. Duconge J, Miranda-Massari JR, Gonz?lez MJ, Taylor PR, Riordan HD, Riordan NH, Casciari JJ, Alliston K. Vitamin C pharmacokinetics after continuous infusion in a patient with prostate cancer. Ann Pharmacother. 2007 Jun; 41(6):1082-3. PMID: 17519294.
      Citations: 6     Fields:    Translation:Humans
    55. Gonz?lez MJ, Herrera FL, Miranda-Massari JM, Guzm?n AM, Riordan NH, Ricart CM. Tumor growth parameters of in-vivo human breast carcinoma: a proposed mathematical model for tumor growth kinetics. P R Health Sci J. 2006 Mar; 25(1):71-3. PMID: 16883681.
      Citations: 1     Fields:    Translation:Humans
    56. Gonzalez MJ, Miranda-Massari JR. Advances in vitamin C research. Integr Cancer Ther. 2006 Mar; 5(1):7-8. PMID: 16484710.
      Citations:    Fields:    Translation:HumansCells
    57. Riordan HD, Casciari JJ, Gonz?lez MJ, Riordan NH, Miranda-Massari JR, Taylor P, Jackson JA. A pilot clinical study of continuous intravenous ascorbate in terminal cancer patients. P R Health Sci J. 2005 Dec; 24(4):269-76. PMID: 16570523.
      Citations: 52     Fields:    Translation:HumansCTClinical Trials
    58. Casciari JJ, Riordan HD, Miranda-Massari JR, Gonzalez MJ. Effects of high dose ascorbate administration on L-10 tumor growth in guinea pigs. P R Health Sci J. 2005 Jun; 24(2):145-50. PMID: 16116933.
      Citations: 10     Fields:    Translation:AnimalsCells
    59. Gonz?lez MJ, Miranda-Massari JR, Mora EM, Guzm?n A, Riordan NH, Riordan HD, Casciari JJ, Jackson JA, Rom?n-Franco A. Orthomolecular oncology review: ascorbic acid and cancer 25 years later. Integr Cancer Ther. 2005 Mar; 4(1):32-44. PMID: 15695476.
      Citations: 33     Fields:    Translation:Humans
    60. Gonzalez MA, Tachibana KE, Laskey RA, Coleman N. Control of DNA replication and its potential clinical exploitation. Nat Rev Cancer. 2005 02; 5(2):135-41. PMID: 15660109.
      Citations: 58     Fields:    Translation:HumansCells
    61. Gonzalez MA, Tachibana KE, Chin SF, Callagy G, Madine MA, Vowler SL, Pinder SE, Laskey RA, Coleman N. Geminin predicts adverse clinical outcome in breast cancer by reflecting cell-cycle progression. J Pathol. 2004 Oct; 204(2):121-30. PMID: 15376260.
      Citations: 35     Fields:    Translation:HumansCells
    62. Gonz?lez MJ, Miranda-Massari JR, Ricart CM. Effect of a dietary supplement combination on weight management, adipose tissue, cholesterol and triglycerides in obese subjects. P R Health Sci J. 2004 Jun; 23(2):121-4. PMID: 15377061.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    63. Mikirova N, Riordan HD, Jackson JA, Wong K, Miranda-Massari JR, Gonzalez MJ. Erythrocyte membrane fatty acid composition in cancer patients. P R Health Sci J. 2004 Jun; 23(2):107-13. PMID: 15377058.
      Citations: 10     Fields:    Translation:HumansCells
    64. Meng X, Riordan NH, Riordan HD, Mikirova N, Jackson J, Gonz?lez MJ, Miranda-Massari JR, Mora E, Trinidad Castillo W. Cell membrane fatty acid composition differs between normal and malignant cell lines. P R Health Sci J. 2004 Jun; 23(2):103-6. PMID: 15377057.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    65. Riordan HD, Riordan NH, Jackson JA, Casciari JJ, Hunninghake R, Gonz?lez MJ, Mora EM, Miranda-Massari JR, Rosario N, Rivera A. Intravenous vitamin C as a chemotherapy agent: a report on clinical cases. P R Health Sci J. 2004 Jun; 23(2):115-8. PMID: 15377059.
      Citations: 24     Fields:    Translation:Humans
    66. Gonz?lez MJ, Ricart CM, Miranda-Massari J. A vitamin, mineral, herb dietary supplement effect on blood glucose in uncontrolled type II diabetic subjects. P R Health Sci J. 2004 Jun; 23(2):119-20. PMID: 15377060.
      Citations:    Fields:    Translation:Humans
    67. Gonzalez MA, Pinder SE, Callagy G, Vowler SL, Morris LS, Bird K, Bell JA, Laskey RA, Coleman N. Minichromosome maintenance protein 2 is a strong independent prognostic marker in breast cancer. J Clin Oncol. 2003 Dec 01; 21(23):4306-13. PMID: 14645419.
      Citations: 59     Fields:    Translation:HumansCells
    68. Riordan HD, Hunninghake RB, Riordan NH, Jackson JJ, Meng X, Taylor P, Casciari JJ, Gonz?lez MJ, Miranda-Massari JR, Mora EM, Rosario N, Rivera A. Intravenous ascorbic acid: protocol for its application and use. P R Health Sci J. 2003 Sep; 22(3):287-90. PMID: 14619456.
      Citations: 20     Fields:    Translation:HumansCells
    69. Gonz?lez MJ, Miranda-Massari JR, Mora EM, Jim?nez IZ, Matos MI, Riordan HD, Casciari JJ, Riordan NH, Rodr?guez M, Guzm?n A. Orthomolecular oncology: a mechanistic view of intravenous ascorbate's chemotherapeutic activity. P R Health Sci J. 2002 Mar; 21(1):39-41. PMID: 12013679.
      Citations: 1     Fields:    Translation:Humans
    70. Gonz?lez MJ, Mora EM, Miranda-Massari JR, Matta J, Riordan HD, Riordan NH. Inhibition of human breast carcinoma cell proliferation by ascorbate and copper. P R Health Sci J. 2002 Mar; 21(1):21-3. PMID: 12013676.
      Citations: 1     Fields:    Translation:HumansCells
    71. Gonz?lez MJ, Miranda-Massari JR, Mora EM, Cruzado NA, Jim?nez I, Rosa M, Matos Vera MI, Santiago C, Rom?n-Eyxarch MI, Rodr?guez JR, P?rez Cort?s C, Riordan NH, Riordan HD, Ricart CM. Integrative medicine: a paradigm shift in medical education and practice. P R Health Sci J. 2000 Dec; 19(4):389-92. PMID: 11293891.
      Citations:    Fields:    Translation:Humans
    72. Gonz?lez L, Nazario CM, Gonz?lez MJ. Nutrition-related problems of pediatric patients with neuromuscular disorders. P R Health Sci J. 2000 Mar; 19(1):35-8. PMID: 10761203.
      Citations: 1     Fields:    Translation:Humans
    73. Santiago E, Gonz?lez MJ, Matos MI, P?rez CM. Dietary fat and breast cancer: a brief update on current knowledge. P R Health Sci J. 1998 Sep; 17(3):273-9. PMID: 9883473.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    74. Santiago E, Gonz?lez MJ, Matos MI, P?rez CM. Association between dietary fat and breast cancer in Puerto Rican postmenopausal women attending a breast cancer clinic. P R Health Sci J. 1998 Sep; 17(3):235-41. PMID: 9883469.
      Citations: 4     Fields:    Translation:Humans
    75. Gonz?lez MJ, Schmitz KJ, Matos MI, L?pez D, Rodr?guez JR, Gorr?n JJ. Folate supplementation and neural tube defects: a review of a public health issue. P R Health Sci J. 1997 Dec; 16(4):387-93. PMID: 9547830.
      Citations: 1     Fields:    Translation:HumansAnimals
    76. Gonz?lez MJ, Nazario CM. The effect of ascorbic acid on human T cells. P R Health Sci J. 1996 Dec; 15(4):309-10. PMID: 9097346.
      Citations:    Fields:    Translation:HumansCells
    77. Gonz?lez MJ, Riordan NH. The paradoxical role of lipid peroxidation on carcinogenesis and tumor growth: a commentary. Med Hypotheses. 1996 Jun; 46(6):503-4. PMID: 8803930.
      Citations: 2     Fields:    Translation:HumansCells
    78. Gonzalez MJ. Fish oil, lipid peroxidation and mammary tumor growth. J Am Coll Nutr. 1995 Aug; 14(4):325-35. PMID: 8568108.
      Citations: 4     Fields:    Translation:AnimalsCells
    79. Petersmark K, Rodr?guez JR, Matos MI, Gonz?lez MJ. Regional differences in fat cell lipolytic mechanisms: a critical review. P R Health Sci J. 1995 Mar; 14(1):11-6. PMID: 7777662.
      Citations:    Fields:    Translation:HumansCells
    80. Gonz?lez MJ, Herrera FL. Cell loss and tumor growth revisited. Med Hypotheses. 1994 Jan; 42(1):39-42. PMID: 8196558.
      Citations:    Fields:    Translation:Humans
    81. Gonzalez MJ, Schemmel RA, Dugan L, Gray JI, Welsch CW. Dietary fish oil inhibits human breast carcinoma growth: a function of increased lipid peroxidation. Lipids. 1993 Sep; 28(9):827-32. PMID: 8231658.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    82. Gonzalez MJ, Gray JI, Schemmel RA, Dugan L, Welsch CW. Lipid peroxidation products are elevated in fish oil diets even in the presence of added antioxidants. J Nutr. 1992 Nov; 122(11):2190-5. PMID: 1432259.
      Citations: 20     Fields:    Translation:AnimalsCells
    83. Gonzalez MJ. Lipid peroxidation and tumor growth: an inverse relationship. Med Hypotheses. 1992 Jun; 38(2):106-10. PMID: 1528153.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    84. Gonzalez MJ, Schemmel RA, Gray JI, Dugan L, Sheffield LG, Welsch CW. Effect of dietary fat on growth of MCF-7 and MDA-MB231 human breast carcinomas in athymic nude mice: relationship between carcinoma growth and lipid peroxidation product levels. Carcinogenesis. 1991 Jul; 12(7):1231-5. PMID: 2070488.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    85. Gonz?lez MJ, Rodr?guez JR. Fat and breast cancer: a mini-review of experimental data on rodents. Bol Asoc Med P R. 1991 Jun; 83(6):264-6. PMID: 1930481.
      Citations:    Fields:    Translation:HumansAnimals
    86. Gonzalez MJ. Serum concentrations and cellular uptake of vitamin E. Med Hypotheses. 1990 Jun; 32(2):107-10. PMID: 2165554.
      Citations: 2     Fields:    Translation:Humans
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