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Annabell C. Segarra

Faculty RankProfessor
InstitutionUniversity of Puerto Rico
DepartmentSchool of Medicine
AddressUniversity of Puerto Rico, Medical Sciences Campus
San Juan PR 936
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    Area of Expertise: Brain development / Epilepsy / Neuroendocrinology / Imaging.

    For more information, please visit: http://md.rcm.upr.edu/physiology/dt_team/dr-annabell-c-segarra/ .

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Men?ndez-Delmestre R, Agosto-Rivera JL, Gonz?lez-Segarra AJ, Segarra AC. Cocaine sensitization in male rats requires activation of estrogen receptors. bioRxiv. 2024 Feb 09. PMID: 38370714.
    2. Novoa J, Rivero CJ, P?rez-Cardona EU, Freire-Arvelo JA, Zegers J, Yarur HE, Santiago-Marerro IG, Agosto-Rivera JL, Gonz?lez-P?rez JL, Gysling K, Segarra AC. Social isolation of adolescent male rats increases anxiety and K+ -induced dopamine release in the nucleus accumbens: Role of CRF-R1. Eur J Neurosci. 2021 08; 54(3):4888-4905. PMID: 34097788.
      Citations: 5     Fields:    Translation:Animals
    3. L?pez OV, Gorantla S, Segarra AC, Andino Norat MC, ?lvarez M, Skolasky RL, Mel?ndez LM. Sigma-1 Receptor Antagonist (BD1047) Decreases Cathepsin B Secretion in HIV-Infected Macrophages Exposed to Cocaine. J Neuroimmune Pharmacol. 2019 06; 14(2):226-240. PMID: 30306495.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    4. Mosquera L, Shepherd L, Torrado AI, Torres-Diaz YM, Miranda JD, Segarra AC. Comparison of Two Methods of Estradiol Replacement: their Physiological and Behavioral Outcomes. J Vet Sci Technol. 2015 Nov 30; 6(6):276. PMID: 26962471.
    5. Zen?n F, Jorge I, Cruz A, Su?rez E, Segarra AC, V?zquez J, Mel?ndez LM, Serrano H. 18O proteomics reveal increased human apolipoprotein CIII in Hispanic HIV-1+ women with HAART that use cocaine. Proteomics Clin Appl. 2016 Feb; 10(2):144-55. PMID: 26255783.
      Citations: 3     Fields:    Translation:Humans
    6. Zen?n F, Segarra AC, Gonzalez M, Mel?ndez LM. Cocaine potentiates cathepsin B secretion and neuronal apoptosis from HIV-infected macrophages. J Neuroimmune Pharmacol. 2014 Dec; 9(5):703-15. PMID: 25209871.
      Citations: 13     Fields:    Translation:HumansCells
    7. Ferchmin PA, Andino M, Reyes Salaman R, Alves J, Velez-Roman J, Cuadrado B, Carrasco M, Torres-Rivera W, Segarra A, Martins AH, Lee JE, Eterovic VA. 4R-cembranoid protects against diisopropylfluorophosphate-mediated neurodegeneration. Neurotoxicology. 2014 Sep; 44:80-90. PMID: 24928201.
      Citations: 27     Fields:    Translation:Animals
    8. Mosquera L, Col?n JM, Santiago JM, Torrado AI, Mel?ndez M, Segarra AC, Rodr?guez-Orengo JF, Miranda JD. Tamoxifen and estradiol improved locomotor function and increased spared tissue in rats after spinal cord injury: their antioxidant effect and role of estrogen receptor alpha. Brain Res. 2014 May 02; 1561:11-22. PMID: 24637260.
      Citations: 32     Fields:    Translation:AnimalsCells
    9. Segarra AC, Torres-D?az YM, Silva RD, Puig-Ramos A, Men?ndez-Delmestre R, Rivera-Berm?dez JG, Amadeo W, Agosto-Rivera JL. Estrogen receptors mediate estradiol's effect on sensitization and CPP to cocaine in female rats: role of contextual cues. Horm Behav. 2014 Feb; 65(2):77-87. PMID: 24355096.
      Citations: 12     Fields:    Translation:Animals
    10. Febo M, Segarra AC, Stolberg TL, Ferris CF. BOLD signal response to cocaine varies with sexual receptivity in female rats. Neuroreport. 2011 Jan 05; 22(1):19-22. PMID: 21048520.
      Citations: 4     Fields:    Translation:Animals
    11. Men?ndez-Delmestre R, Segarra AC. Testosterone is essential for cocaine sensitization in male rats. Physiol Behav. 2011 Jan 10; 102(1):96-104. PMID: 20932851.
      Citations: 7     Fields:    Translation:Animals
    12. Segarra AC, Agosto-Rivera JL, Febo M, Lugo-Escobar N, Men?ndez-Delmestre R, Puig-Ramos A, Torres-Diaz YM. Estradiol: a key biological substrate mediating the response to cocaine in female rats. Horm Behav. 2010 Jun; 58(1):33-43. PMID: 20026119.
      Citations: 41     Fields:    Translation:Animals
    13. Puig-Ramos A, Santiago GS, Segarra AC. U-69593, a kappa opioid receptor agonist, decreases cocaine-induced behavioral sensitization in female rats. Behav Neurosci. 2008 Feb; 122(1):151-60. PMID: 18298258.
      Citations: 12     Fields:    Translation:Animals
    14. Cruz-Orengo L, Figueroa JD, Vel?zquez I, Torrado A, Ort?z C, Hern?ndez C, Puig A, Segarra AC, Whittemore SR, Miranda JD. Blocking EphA4 upregulation after spinal cord injury results in enhanced chronic pain. Exp Neurol. 2006 Dec; 202(2):421-33. PMID: 16959251.
      Citations: 25     Fields:    Translation:AnimalsCells
    15. Febo M, Segarra AC, Nair G, Schmidt K, Duong TQ, Ferris CF. The neural consequences of repeated cocaine exposure revealed by functional MRI in awake rats. Neuropsychopharmacology. 2005 May; 30(5):936-43. PMID: 15637636.
      Citations: 49     Fields:    Translation:Animals
    16. Febo M, Ferris CF, Segarra AC. Estrogen influences cocaine-induced blood oxygen level-dependent signal changes in female rats. J Neurosci. 2005 Feb 02; 25(5):1132-6. PMID: 15689549.
      Citations: 16     Fields:    Translation:Animals
    17. Febo M, Segarra AC, Tenney JR, Brevard ME, Duong TQ, Ferris CF. Imaging cocaine-induced changes in the mesocorticolimbic dopaminergic system of conscious rats. J Neurosci Methods. 2004 Oct 30; 139(2):167-76. PMID: 15488229.
      Citations: 39     Fields:    Translation:Animals
    18. Febo M, Segarra AC. Cocaine alters GABA(B)-mediated G-protein activation in the ventral tegmental area of female rats: modulation by estrogen. Synapse. 2004 Oct; 54(1):30-6. PMID: 15300882.
      Citations: 10     Fields:    Translation:AnimalsCells
    19. Febo M, Gonz?lez-Rodr?guez LA, Cap?-Ramos DE, Gonz?lez-Segarra NY, Segarra AC. Estrogen-dependent alterations in D2/D3-induced G protein activation in cocaine-sensitized female rats. J Neurochem. 2003 Jul; 86(2):405-12. PMID: 12871581.
      Citations: 27     Fields:    Translation:AnimalsCells
    20. Mej?as-Aponte CA, Jim?nez-Rivera CA, Segarra AC. Sex differences in models of temporal lobe epilepsy: role of testosterone. Brain Res. 2002 Jul 19; 944(1-2):210-8. PMID: 12106683.
      Citations: 37     Fields:    Translation:AnimalsCells
    21. Febo M, Jim?nez-Rivera CA, Segarra AC. Estrogen and opioids interact to modulate the locomotor response to cocaine in the female rat. Brain Res. 2002 Jul 05; 943(1):151-61. PMID: 12088849.
      Citations: 15     Fields:    Translation:Animals
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