Mahavir B. Chougule, Assistant Professor of the Department of Pharmaceutical Sciences, College of Pharmacy, University of Hawaii at Hilo, HI, USA, investigates the use of therapeutic agent, siRNA, proteins and targeted nanotechnology based formulations for treatment of cancer and pulmonary disorders. His research work is focused on targeted delivery using nanocarriers to improve the efficacy and minimize the adverse side effects. Chougule has shown that the inhalation delivery of anticancer drug loaded nanoparticle significantly inhibits tumor growth compared to aerosolized solution. Chougule has also investigated the anticancer activity and molecular mechanism of natural compounds against lung and breast cancer. He also developed the spray dried nano-liposomal dry powder inhalers and topical nanocarrier cream formulation for treatment of skin disorders.
Dr. Chougule has more than 7 years of professional experience in developmental therapeutics and biopharmaceuticals. he has has published 21 research articles, 2 review article, 4 book chapters, and presented work in more than 50 scientific conferences. In addition, he is also an inventor in the 8 patents. He is also serving as member of editorial board on 5 international journals and recipient of several awards including AACR Minority-Serving Institution Faculty Scholar in Cancer Research Awards.
Research Interests: Cancer, asthma, nanotechnology, small compound and gene/protein based drug delivery, Inhalation delivery, topical/transdermal delivery, Molecular biology, cell culture, and animal models.