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Lynn Francesconi

TitleProfessor of Chemistry
InstitutionHunter College, CUNY
AddressRoom 1307 HN, Hunter College, CUNY
695 Park Avenue
New York NY 10065
Phone(212) 772-5353
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    SC1CA138177     (FRANCESCONI, LYNN CAROL)Jul 14, 2008 - Aug 31, 2010
    Radiometal Chelates for Targeted Therapy of Melanoma
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hatcher-Lamarre JL, Sanders VA, Rahman M, Cutler CS, Francesconi LC. Alpha emitting nuclides for targeted therapy. Nucl Med Biol. 2021 01; 92:228-240. PMID: 33558017.
      Citations:    Fields:    
    2. Younes A, Ali JS, Nur MT, Duda A, Wang J, Samson J, Kawamura A, Francesconi L, Alexandratos S, Drain CM. Pistachio shells as remediating agents for uranium in contaminated industrial seawater. J Environ Radioact. 2020 Jun; 217:106209. PMID: 32217241.
      Citations:    Fields:    Translation:AnimalsCellsPHPublic Health
    3. MacPherson DS, Fung K, Cook BE, Francesconi LC, Zeglis BM. A brief overview of metal complexes as nuclear imaging agents. Dalton Trans. 2019 Oct 07; 48(39):14547-14565. PMID: 31556418.
      Citations: 1     Fields:    Translation:HumansAnimals
    4. Bhupathiraju NVSDK, Younes A, Cao M, Ali J, Cicek HT, Tully KM, Ponnala S, Babich JW, Deri MA, Lewis JS, Francesconi LC, Drain CM. Improved synthesis of the bifunctional chelator p-SCN-Bn-HOPO. Org Biomol Chem. 2019 07 17; 17(28):6866-6871. PMID: 31268109.
      Citations:    Fields:    Translation:Cells
    5. Sanders VA, Iskhakov D, Abdel-Atti D, Devany M, Neary MC, Czerwinski KR, Francesconi LC. Synthesis, characterization and biological studies of rhenium, technetium-99m and rhenium-188 pentapeptides. Nucl Med Biol. 2019 Jan - Feb; 68-69:1-13. PMID: 30578134.
      Citations:    Fields:    Translation:AnimalsCells
    6. Poty S, Francesconi LC, McDevitt MR, Morris MJ, Lewis JS. a-Emitters for Radiotherapy: From Basic Radiochemistry to Clinical Studies-Part 1. J Nucl Med. 2018 06; 59(6):878-884. PMID: 29545378.
      Citations: 14     Fields:    Translation:Humans
    7. Poty S, Francesconi LC, McDevitt MR, Morris MJ, Lewis JS. a-Emitters for Radiotherapy: From Basic Radiochemistry to Clinical Studies-Part 2. J Nucl Med. 2018 07; 59(7):1020-1027. PMID: 29496984.
      Citations: 9     Fields:    Translation:HumansAnimals
    8. Gupta R, Huang W, Francesconi LC, Polenova T. Effect of positional isomerism and vanadium substitution on 51V magic angle spinning NMR Spectra Of Wells-Dawson polyoxotungstates. Solid State Nucl Magn Reson. 2017 Jul - Aug; 84:28-33. PMID: 27998683.
      Citations:    Fields:    Translation:Cells
    9. Yazdani A, Bilton H, Vito A, Genady AR, Rathmann SM, Ahmad Z, Janzen N, Czorny S, Zeglis BM, Francesconi LC, Valliant JF. A Bone-Seeking trans-Cyclooctene for Pretargeting and Bioorthogonal Chemistry: A Proof of Concept Study Using 99mTc- and 177Lu-Labeled Tetrazines. J Med Chem. 2016 Oct 27; 59(20):9381-9389. PMID: 27676258.
      Citations: 11     Fields:    Translation:AnimalsCells
    10. Deri MA, Ponnala S, Kozlowski P, Burton-Pye BP, Cicek HT, Hu C, Lewis JS, Francesconi LC. p-SCN-Bn-HOPO: A Superior Bifunctional Chelator for (89)Zr ImmunoPET. Bioconjug Chem. 2015 Dec 16; 26(12):2579-91. PMID: 26550847.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    11. Cristaudo A, Francesconi L, Ambrifi M, Frasca M, Cavallotti C, Sperduti E. Efficacy of an emollient dermoprotective cream in the treatment of elderly skin affected by xerosis. G Ital Dermatol Venereol. 2015 Jun; 150(3):297-302. PMID: 25946673.
      Citations: 2     Fields:    Translation:Humans
    12. Wagner T, Zeglis BM, Groveman S, Hille C, Pöthig A, Francesconi LC, Herrmann WA, Kühn FE, Reiner T. Synthesis of the first radiolabeled 188Re N-heterocyclic carbene complex and initial studies on its potential use in radiopharmaceutical applications. J Labelled Comp Radiopharm. 2014 Jun 15; 57(7):441-7. PMID: 24889257.
      Citations:    Fields:    
    13. Deri MA, Ponnala S, Zeglis BM, Pohl G, Dannenberg JJ, Lewis JS, Francesconi LC. Alternative chelator for 8?Zr radiopharmaceuticals: radiolabeling and evaluation of 3,4,3-(LI-1,2-HOPO). J Med Chem. 2014 Jun 12; 57(11):4849-60. PMID: 24814511.
      Citations: 40     Fields:    Translation:Animals
    14. Thompson S, Ballard B, Jiang Z, Revskaya E, Sisay N, Miller WH, Cutler CS, Dadachova E, Francesconi LC. 166Ho and 90Y labeled 6D2 monoclonal antibody for targeted radiotherapy of melanoma: comparison with 188Re radiolabel. Nucl Med Biol. 2014 Mar; 41(3):276-81. PMID: 24533987.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    15. Poineau F, Weck PF, Burton-Pye BP, Denden I, Kim E, Kerlin W, German KE, Fattahi M, Francesconi LC, Sattelberger AP, Czerwinski KR. Reactivity of HTcO(4) with methanol in sulfuric acid: Tc-sulfate complexes revealed by XAFS spectroscopy and first principles calculations. Dalton Trans. 2013 Apr 07; 42(13):4348-52. PMID: 23403900.
      Citations: 3     Fields:    Translation:Cells
    16. Gordon JC, Czerwinski K, Francesconi L. Preface: forum on aspects of inorganic chemistry related to nuclear energy. Inorg Chem. 2013 Apr 01; 52(7):3405-6. PMID: 23541298.
      Citations: 1     Fields:    
    17. Deri MA, Zeglis BM, Francesconi LC, Lewis JS. PET imaging with 8?Zr: from radiochemistry to the clinic. Nucl Med Biol. 2013 Jan; 40(1):3-14. PMID: 22998840.
      Citations: 105     Fields:    Translation:HumansAnimals
    18. McGregor D, Burton-Pye BP, Mbomekalle IM, Aparicio PA, Romo S, López X, Poblet JM, Francesconi LC. 99Tc and Re incorporated into metal oxide polyoxometalates: oxidation state stability elucidated by electrochemistry and theory. Inorg Chem. 2012 Aug 20; 51(16):9017-28. PMID: 22839965.
      Citations:    Fields:    Translation:CellsPHPublic Health
    19. Radivojevic I, Bazzan G, Burton-Pye BP, Ithisuphalap K, Saleh R, Durstock MF, Francesconi LC, Drain CM. Zirconium((IV)) and Hafnium((IV)) Porphyrin and Phthalocyanine Complexes as New Dyes for Solar Cell Devices. J Phys Chem C Nanomater Interfaces. 2012 Aug 02; 116(30):15867-15877. PMID: 22962625.
    20. Burton-Pye BP, Radivojevic I, McGregor D, Mbomekalle IM, Lukens WW, Francesconi LC. Photoreduction of 99Tc pertechnetate by nanometer-sized metal oxides: new strategies for formation and sequestration of low-valent technetium. J Am Chem Soc. 2011 Nov 23; 133(46):18802-15. PMID: 21985281.
      Citations:    Fields:    Translation:Cells
    21. Ballard B, Jiang Z, Soll CE, Revskaya E, Cutler CS, Dadachova E, Francesconi LC. In vitro and in vivo evaluation of melanin-binding decapeptide 4B4 radiolabeled with 177Lu, 166Ho, and 153Sm radiolanthanides for the purpose of targeted radionuclide therapy of melanoma. Cancer Biother Radiopharm. 2011 Oct; 26(5):547-56. PMID: 21970319.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    22. Burton-Pye BP, Francesconi LC. Speciation of organic-soluble europium(III) a1-Wells-Dawson complexes. Dalton Trans. 2011 May 07; 40(17):4421-33. PMID: 21409197.
      Citations:    Fields:    Translation:Cells
    23. McGregor D, Burton-Pye BP, Howell RC, Mbomekalle IM, Lukens WW, Bian F, Mausolf E, Poineau F, Czerwinski KR, Francesconi LC. Synthesis, structure elucidation, and redox properties of 99Tc complexes of lacunary Wells-Dawson polyoxometalates: insights into molecular 99Tc-metal oxide interactions. Inorg Chem. 2011 Mar 07; 50(5):1670-81. PMID: 21268605.
      Citations:    Fields:    
    24. Antonio MR, Jing J, Burton-Pye BP, Francesconi LC. Series behavior of lanthanoid(III) complexes with the alpha-1-Wells-Dawson heteropolyoxoanion in acetonitrile: electrochemistry and Ln coordination. Dalton Trans. 2010 Sep 14; 39(34):7980-92. PMID: 20672167.
      Citations: 1     Fields:    Translation:Cells
    25. Jyothish K, Vemula PK, Jadhav SR, Francesconi LC, John G. Self-standing, metal nanoparticle embedded transparent films from multi-armed cardanol conjugates through in situ synthesis. Chem Commun (Camb). 2009 Sep 28; (36):5368-70. PMID: 19724787.
      Citations:    Fields:    
    26. Falber A, Burton-Pye BP, Radivojevic I, Todaro L, Saleh R, Francesconi L, Drain CM. Ternary Porphyrinato Hf(IV) and Zr(IV) - Polyoxometalate Complexes. Eur J Inorg Chem. 2009 Jun 01; 2009(17):2459-2466. PMID: 20543903.
    27. Mishra PP, Jing J, Francesconi LC, Liu T. Self-assembly of Yttrium-containing lacunary polyoxotungstate macroanions in solution with controllable supramolecular structure size by pH or solvent content. Langmuir. 2008 Sep 02; 24(17):9308-13. PMID: 18680322.
      Citations: 1     Fields:    Translation:Cells
    28. Jing J, Burton-Pye BP, Francesconi LC, Antonio MR. Europium(III) reduction and speciation within a Wells-Dawson heteropolytungstate. Inorg Chem. 2008 Aug 04; 47(15):6889-99. PMID: 18616240.
      Citations: 1     Fields:    Translation:Cells
    29. Bazzan G, Smith W, Francesconi LC, Drain CM. Electrostatic self-organization of robust porphyrin-polyoxometalate films. Langmuir. 2008 Apr 01; 24(7):3244-9. PMID: 18321141.
      Citations: 5     Fields:    Translation:Cells
    30. Huang W, Schopfer M, Zhang C, Howell RC, Todaro L, Gee BA, Francesconi LC, Polenova T. 31P magic angle spinning NMR spectroscopy of paramagnetic rare-earth-substituted Keggin and Wells-Dawson solids. J Am Chem Soc. 2008 Jan 16; 130(2):481-90. PMID: 18095677.
      Citations: 1     Fields:    
    31. Huang W, Francesconi LC, Polenova T. (31)P magic angle spinning NMR spectroscopy for probing local environments in paramagnetic europium-substituted wells-dawson polyoxotungstates. Inorg Chem. 2007 Sep 17; 46(19):7861-9. PMID: 17715914.
      Citations: 1     Fields:    
    32. Cantorias MV, Howell RC, Todaro L, Cyr JE, Berndorff D, Rogers RD, Francesconi LC. MO tripeptide diastereomers (M=99/99mTc, Re): models to identify the structure of 99mTc peptide targeted radiopharmaceuticals. Inorg Chem. 2007 Sep 03; 46(18):7326-40. PMID: 17691766.
      Citations: 4     Fields:    Translation:AnimalsCells
    33. Cyr JE, Pearson DA, Nelson CA, Lyons BA, Zheng Y, Bartis J, He J, Cantorias MV, Howell RC, Francesconi LC. Isolation, characterization, and biological evaluation of syn and anti diastereomers of [(99m)Tc]technetium depreotide: a somatostatin receptor binding tumor imaging agent. J Med Chem. 2007 Sep 06; 50(18):4295-303. PMID: 17691760.
      Citations: 2     Fields:    Translation:AnimalsCells
    34. Huang W, Schopfer M, Zhang C, Howell RC, Gee BA, Francesconi LC, Polenova T. Probing local environments in paramagnetic europium-substituted Keggin solids by 31P magic angle spinning NMR spectroscopy. J Phys Chem B. 2006 Jun 29; 110(25):12340-50. PMID: 16800557.
      Citations: 2     Fields:    
    35. Boglio C, Lenoble G, Duhayon C, Hasenknopf B, Thouvenot R, Zhang C, Howell RC, Burton-Pye BP, Francesconi LC, Lacôte E, Thorimbert S, Malacria M, Afonso C, Tabet JC. Production and reactions of organic-soluble lanthanide complexes of the monolacunary Dawson [alpha1-P2W17O61]10- polyoxotungstate. Inorg Chem. 2006 Feb 06; 45(3):1389-98. PMID: 16441151.
      Citations: 1     Fields:    
    36. Zhang X, Zhang C, Guo H, Huang W, Polenova T, Francesconi LC, Akins DL. Optical spectra of a novel polyoxometalate occluded within modified MCM-41. J Phys Chem B. 2005 Oct 20; 109(41):19156-60. PMID: 16853470.
      Citations: 2     Fields:    Translation:Cells
    37. Zhang C, Howell RC, Luo QH, Fieselmann HL, Todaro LJ, Francesconi LC. Influence of steric and electronic properties of the defect site, lanthanide ionic radii, and solution conditions on the composition of lanthanide(III) alpha1-P2W17O6110- polyoxometalates. Inorg Chem. 2005 May 16; 44(10):3569-78. PMID: 15877440.
      Citations: 1     Fields:    Translation:Cells
    38. Banerjee SR, Maresca KP, Francesconi L, Valliant J, Babich JW, Zubieta J. New directions in the coordination chemistry of 99mTc: a reflection on technetium core structures and a strategy for new chelate design. Nucl Med Biol. 2005 Jan; 32(1):1-20. PMID: 15691657.
      Citations: 28     Fields:    
    39. Zhang C, Howell RC, Scotland KB, Perez FG, Todaro L, Francesconi LC. Aqueous speciation studies of europium(III) phosphotungstate. Inorg Chem. 2004 Nov 29; 43(24):7691-701. PMID: 15554634.
      Citations: 5     Fields:    Translation:Cells
    40. Huang W, Todaro L, Yap GP, Beer R, Francesconi LC, Polenova T. 51V magic angle spinning NMR spectroscopy of Keggin anions [PVnW12-nO40](3+n)-: effect of countercation and vanadium substitution on fine structure constants. J Am Chem Soc. 2004 Sep 22; 126(37):11564-73. PMID: 15366903.
      Citations: 8     Fields:    Translation:Cells
    41. Francesconi LC, Zheng Y, Bartis J, Blumenstein M, Costello C, De Rosch MA. Preparation and characterization of [99TcO] apcitide: a technetium labeled peptide. Inorg Chem. 2004 May 03; 43(9):2867-75. PMID: 15106974.
      Citations: 4     Fields:    Translation:Cells
    42. Huang W, Todaro L, Francesconi LC, Polenova T. 51V magic angle spinning NMR spectroscopy of six-coordinate Lindqvist oxoanions: a sensitive probe for the electronic environment in vanadium-containing polyoxometalates. Counterions dictate the 51V fine structure constants in polyoxometalate solids. J Am Chem Soc. 2003 May 14; 125(19):5928-38. PMID: 12733933.
      Citations: 7     Fields:    
    43. Luo Q, Howell RC, Bartis J, Dankova M, Horrocks WD, Rheingold AL, Francesconi LC. Lanthanide complexes of [alpha-2-P2W17O61]10-: solid state and solution studies. Inorg Chem. 2002 Nov 18; 41(23):6112-7. PMID: 12425640.
      Citations: 2     Fields:    Translation:Cells
    44. Efange SM, Tu Z, von Hohenberg K, Francesconi L, Howell RC, Rampersad MV, Todaro LJ, Papke RL, Kung MP. 2-(2-Piperidyl)- and 2-(2-pyrrolidyl)chromans as nicotine agonists: synthesis and preliminary pharmacological characterization. J Med Chem. 2001 Dec 20; 44(26):4704-15. PMID: 11741488.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    45. Howell RC, Perez FG, Jain S, DeW Horrocks W, Rheingold AL, Francesconi LC. A New Type of Heteropolyoxometalates formed from Lacunary Polyoxotungstate Ions and Europium or Yttrium Cations. Angew Chem Int Ed Engl. 2001 Nov 05; 40(21):4031-4034. PMID: 29712261.
      Citations:    Fields:    
    46. Howell RC, Perez FG, Jain S, DeW Horrocks W, Rheingold AL, Francesconi LC. A New Type of Heteropolyoxometalates formed from Lacunary Polyoxotungstate Ions and Europium or Yttrium Cations We gratefully acknowledge Dr. Gerard Parkin and Dr. Brian Bridgewater for the use of the diffractometer at Columbia University and helpful discussions. Supported by NSF-CHE9502213, NIH-GM60654-01 (LCF), NIH-MARC (FGP), NSF-CHE-9705788 (W.D.H), and NSF Grant PCM8111745 for the purchase of the 400 MHz Spectrometer. Infrastructure at Hunter College is supported in part by NIH-Research Centers in Minority Institutions Grant RR03037-08S2. Angew Chem Int Ed Engl. 2001 11 05; 40(21):4031-4034. PMID: 12404483.
      Citations: 2     Fields:    
    47. Luo QH, Howell RC, Dankova M, Bartis J, Williams CW, Horrocks WD, Young VG, Rheingold AL, Francesconi LC, Antonio MR. Coordination of rare-earth elements in complexes with monovacant Wells-Dawson polyoxoanions. Inorg Chem. 2001 Apr 09; 40(8):1894-901. PMID: 11312747.
      Citations: 1     Fields:    Translation:Cells
    48. Bartis J, Dankova M, Lessmann JJ, Luo QH, Horrocks WD, Francesconi LC. Lanthanide Complexes of the alpha-1 Isomer of the [P(2)W(17)O(61)](10-) Heteropolytungstate: Preparation, Stoichiometry, and Structural Characterization by (183)W and (31)P NMR Spectroscopy and Europium(III) Luminescence Spectroscopy. Inorg Chem. 1999 Mar 22; 38(6):1042-1053. PMID: 11670884.
      Citations: 2     Fields:    
    49. Zheng YY, Saluja S, Yap GP, Blumenstein M, Rheingold AL, Francesconi LC. Gallium and Indium Complexes of Bis(amino thiol) (N(2)S(2)) Ligands. Inorg Chem. 1996 Nov 06; 35(23):6656-6666. PMID: 11666826.
      Citations: 2     Fields:    
    50. Bartis J, Kunina Y, Blumenstein M, Francesconi LC. Preparation and Tungsten-183 NMR Characterization of [alpha-1-P(2)W(17)O(61)](10)(-), [alpha-1-Zn(H(2)O)P(2)W(17)O(61)](8)(-), and [alpha-2-Zn(H(2)O)P(2)W(17)O(61)](8)(-). Inorg Chem. 1996 Mar 13; 35(6):1497-1501. PMID: 11666364.
      Citations:    Fields:    
    51. Francesconi LC, Yang YY, Kung MP, Zhang XX, Billings JJ, Guo YZ, Kung HF. Technetium-99m N,N'-bis(2-mercapto-2-methylpropyl)-2-aminobenzylamine: technetium-99m complexes of a novel bis(aminoethanethiol) ligand. J Med Chem. 1994 Sep 30; 37(20):3282-8. PMID: 7932555.
      Citations: 1     Fields:    Translation:AnimalsCells
    52. Canney DJ, Billings J, Francesconi LC, Guo YZ, Haggerty BS, Rheingold AL, Kung HF. Dicarboxylate diamide dimercaptide (N2S2) technetium-99m complexes: synthesis and biological evaluation as potential renal radiopharmaceuticals. J Med Chem. 1993 Apr 16; 36(8):1032-40. PMID: 8478903.
      Citations: 2     Fields:    Translation:Animals
    53. Ohmomo Y, Francesconi L, Kung MP, Kung HF. New conformationally restricted 99mTc N2S2 complexes as myocardial perfusion imaging agents. J Med Chem. 1992 Jan; 35(1):157-62. PMID: 1732524.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    54. Kung HF, Liu BL, Mankoff D, Kung MP, Billings JJ, Francesconi L, Alavi A. A new myocardial imaging agent: synthesis, characterization, and biodistribution of gallium-68-BAT-TECH. J Nucl Med. 1990 Oct; 31(10):1635-40. PMID: 2213185.
      Citations: 7     Fields:    Translation:Animals
    55. Abate L, Croci F, Francesconi L, Bayeli PF. [A retrospective clinico-endoscopic study of colorectal cancer. Personal case histories]. Minerva Med. 1989 Mar; 80(3):249-53. PMID: 2717044.
      Citations:    Fields:    Translation:HumansPHPublic Health
    56. Bayeli P, Abate L, Francesconi L, Lio R, Cetta F, Tanzini G. [Mesenteric fibrosis. Apropos of 1 of our cases]. Minerva Dietol Gastroenterol. 1988 Oct-Dec; 34(4):273-6. PMID: 3247062.
      Citations:    Fields:    Translation:Humans
    57. Acetoso M, Francesconi L. [Evaluation of immune status in rubella infection in the pregnant population of the U.S.L. 3 of Pesaro 1981-1985]. Quad Sclavo Diagn. 1986 Sep; 22(3):283-90. PMID: 3615801.
      Citations:    Fields:    Translation:HumansPHPublic Health
    58. Pasternack RF, Huber PR, Boyd P, Engasser G, Francesconi L, Gibbs E, Fasella P, Venturo GC, Hinds Lde C. On the aggregation of meso-substituted water-soluble porphyrins. J Am Chem Soc. 1972 Jun 28; 94(13):4511-7. PMID: 5036163.
      Citations: 30     Fields:    
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