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Michele Carbone, MD, PhD.

Title
Faculty RankProfessor
InstitutionUniversity of Hawaii
DepartmentCancer Biology
AddressUniversity of Hawaii Cancer Center
701 Ilalo Street
Honolulu HI 96816
Phone8084404596
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    Collapse Research 
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    P30CA071789     (HOLCOMBE, RANDALL F)Jul 1, 1997 - Sep 28, 2012
    NIH/NCI
    University of Hawaii Cancer Center CCSG
    Role: Co-Principal Investigator

    R29CA077220     (CARBONE, MICHELE)Aug 1, 1997 - Jul 31, 2003
    NIH/NCI
    SV40-LIKE SEQUENCES IN HUMAN TUMORS ANALYSES
    Role: Principal Investigator

    R01CA092657     (CARBONE, MICHELE)Apr 1, 2002 - May 31, 2006
    NIH/NCI
    SV40 sequences in human tumors: analysis &biologic*
    Role: Principal Investigator

    R01CA106567     (CARBONE, MICHELE)Mar 8, 2005 - May 31, 2006
    NIH/NCI
    Role of Cell Mediators in Asbestos-SV40 Carcinogenesis
    Role: Principal Investigator

    P01CA114047     (CARBONE, MICHELE)Sep 15, 2006 - Aug 31, 2013
    NIH/NCI
    Pathogenesis of mesothelioma
    Role: Principal Investigator

    R01CA198138     (CARBONE, MICHELE)Jul 6, 2015 - Jun 30, 2020
    NIH/NCI
    Germline BAP1 Mutations and Malignant Mesothelioma: Mechanisms and Early Detection
    Role: Principal Investigator

    R01ES030948     (CARBONE, MICHELE)Aug 15, 2019 - Jun 30, 2022
    NIH/NIEHS
    Influence of germline mutations on susceptibility to environmental carcinogens
    Role: Principal Investigator

    R01CA237235     (CARBONE, MICHELE)Dec 13, 2019 - Nov 30, 2024
    NIH/NCI
    Mechanisms of BAP1 activity in human cancer development
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Xue J, Suarez JS, Minaai M, Li S, Gaudino G, Pass HI, Carbone M, Yang H. HMGB1 as a therapeutic target in disease. J Cell Physiol. 2020 Oct 26. PMID: 33107103.
      Citations:    Fields:    
    2. Xue J, Patergnani S, Giorgi C, Suarez J, Goto K, Bononi A, Tanji M, Novelli F, Pastorino S, Xu R, Caroccia N, Dogan AU, Pass HI, Tognon M, Pinton P, Gaudino G, Mak TW, Carbone M, Yang H. Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy. Proc Natl Acad Sci U S A. 2020 10 13; 117(41):25543-25552. PMID: 32999071.
      Citations: 1     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    3. Pass HI, Alimi M, Carbone M, Yang H, Goparaju CM. Mesothelioma Biomarkers: Discovery in Search of Validation. Thorac Surg Clin. 2020 Nov; 30(4):395-423. PMID: 33012429.
      Citations:    Fields:    
    4. Pass HI, Alimi M, Carbone M, Yang H, Goparaju CM. Mesothelioma Biomarkers: A Review Highlighting Contributions from the Early Detection Research Network. Cancer Epidemiol Biomarkers Prev. 2020 Dec; 29(12):2524-2540. PMID: 32699075.
      Citations:    Fields:    
    5. Carbone M, Harbour JW, Brugarolas J, Bononi A, Pagano I, Dey A, Krausz T, Pass HI, Yang H, Gaudino G. Biological Mechanisms and Clinical Significance of BAP1 Mutations in Human Cancer. Cancer Discov. 2020 Aug; 10(8):1103-1120. PMID: 32690542.
      Citations: 2     Fields:    
    6. Carbone M. Transitional Mesothelioma and Artificial Intelligence: Do We Need One More Subtype? and Do We Need Computers to Identify Them? J Thorac Oncol. 2020 06; 15(6):884-887. PMID: 32471562.
      Citations: 1     Fields:    Translation:Humans
    7. Carbone M, Arron ST, Beutler B, Bononi A, Cavenee W, Cleaver JE, Croce CM, D'Andrea A, Foulkes WD, Gaudino G, Groden JL, Henske EP, Hickson ID, Hwang PM, Kolodner RD, Mak TW, Malkin D, Monnat RJ, Novelli F, Pass HI, Petrini JH, Schmidt LS, Yang H. Tumour predisposition and cancer syndromes as models to study gene-environment interactions. Nat Rev Cancer. 2020 09; 20(9):533-549. PMID: 32472073.
      Citations: 2     Fields:    Translation:HumansAnimals
    8. Napolitano A, Antoine DJ, Pellegrini L, Baumann F, Pagano I, Pastorino S, Goparaju CM, Prokrym K, Canino C, Pass HI, Carbone M, Yang H. Expression of Concern: HMGB1 and Its Hyperacetylated Isoform are Sensitive and Specific Serum Biomarkers to Detect Asbestos Exposure and to Identify Mesothelioma Patients. Clin Cancer Res. 2020 03 15; 26(6):1529. PMID: 32169964.
      Citations:    Fields:    
    9. Carbone M, Green JB, Bucci EM, Lednicky JA. Coronaviruses: Facts, Myths, and Hypotheses. J Thorac Oncol. 2020 05; 15(5):675-678. PMID: 32151778.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    10. Carbone M. This special volume of mesothelioma is dedicated to my friend Adi Gazdar. Transl Lung Cancer Res. 2020 Feb; 9(Suppl 1):S1-S2. PMID: 32206566.
      Citations:    
    11. Lee HJ, Pham T, Chang MT, Barnes D, Cai AG, Noubade R, Totpal K, Chen X, Tran C, Hagenbeek T, Wu X, Eastham-Anderson J, Tao J, Lee W, Bastian BC, Carbone M, Webster JD, Dey A. The Tumor Suppressor BAP1 Regulates the Hippo Pathway in Pancreatic Ductal Adenocarcinoma. Cancer Res. 2020 04 15; 80(8):1656-1668. PMID: 31988076.
      Citations:    Fields:    Translation:Humans
    12. Carbone M, Melino G. Stearoyl CoA Desaturase Regulates Ferroptosis in Ovarian Cancer Offering New Therapeutic Perspectives. Cancer Res. 2019 Oct 15; 79(20):5149-5150. PMID: 31615810.
      Citations: 3     Fields:    Translation:HumansAnimals
    13. Carbone M, Melino G. Lipid metabolism offers anticancer treatment by regulating ferroptosis. Cell Death Differ. 2019 12; 26(12):2516-2519. PMID: 31543514.
      Citations:    Fields:    Translation:Humans
    14. Carbone M, Adusumilli PS, Alexander HR, Baas P, Bardelli F, Bononi A, Bueno R, Felley-Bosco E, Galateau-Salle F, Jablons D, Mansfield AS, Minaai M, de Perrot M, Pesavento P, Rusch V, Severson DT, Taioli E, Tsao A, Woodard G, Yang H, Zauderer MG, Pass HI. Mesothelioma: Scientific clues for prevention, diagnosis, and therapy. CA Cancer J Clin. 2019 09; 69(5):402-429. PMID: 31283845.
      Citations: 27     Fields:    Translation:HumansPHPublic Health
    15. Tsao MS, Carbone M, Galateau-Salle F, Moreira AL, Nicholson AG, Roden AC, Adjei AA, Aubry MC, Fennell DA, Gomez D, Harpole D, Hesdorffer M, Hirsch FR, Liu G, Malik S, Nowak A, Peikert T, Salgia R, Szlosarek P, Taioli E, Yang H, Tsao A, Mansfield AS. Pathologic Considerations and Standardization in Mesothelioma Clinical Trials. J Thorac Oncol. 2019 10; 14(10):1704-1717. PMID: 31260832.
      Citations:    Fields:    Translation:Humans
    16. Bertino P, Premeaux TA, Fujita T, Haun BK, Marciel MP, Hoffmann FW, Garcia A, Yiang H, Pastorino S, Carbone M, Niki T, Berestecky J, Hoffmann PR, Ndhlovu LC. Targeting the C-terminus of galectin-9 induces mesothelioma apoptosis and M2 macrophage depletion. Oncoimmunology. 2019; 8(8):1601482. PMID: 31413910.
      Citations:    
    17. Carbone M, Yang H, Gaudino G. Does Chromothripsis Make Mesothelioma an Immunogenic Cancer? J Thorac Oncol. 2019 02; 14(2):157-159. PMID: 30598368.
      Citations:    Fields:    Translation:Humans
    18. Affar EB, Carbone M. BAP1 regulates different mechanisms of cell death. Cell Death Dis. 2018 11 19; 9(12):1151. PMID: 30455474.
      Citations: 5     Fields:    Translation:Humans
    19. Pastorino S, Yoshikawa Y, Pass HI, Emi M, Nasu M, Pagano I, Takinishi Y, Yamamoto R, Minaai M, Hashimoto-Tamaoki T, Ohmuraya M, Goto K, Goparaju C, Sarin KY, Tanji M, Bononi A, Napolitano A, Gaudino G, Hesdorffer M, Yang H, Carbone M. A Subset of Mesotheliomas With Improved Survival Occurring in Carriers of BAP1 and Other Germline Mutations. J Clin Oncol. 2018 Oct 30; JCO2018790352. PMID: 30376426.
      Citations: 17     Fields:    
    20. Daou S, Barbour H, Ahmed O, Masclef L, Baril C, Sen Nkwe N, Tchelougou D, Uriarte M, Bonneil E, Ceccarelli D, Mashtalir N, Tanji M, Masson JY, Thibault P, Sicheri F, Yang H, Carbone M, Therrien M, Affar EB. Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1. Nat Commun. 2018 10 22; 9(1):4385. PMID: 30349006.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    21. Carbone M, Amelio I, Affar EB, Brugarolas J, Cannon-Albright LA, Cantley LC, Cavenee WK, Chen Z, Croce CM, Andrea A, Gandara D, Giorgi C, Jia W, Lan Q, Mak TW, Manley JL, Mikoshiba K, Onuchic JN, Pass HI, Pinton P, Prives C, Rothman N, Sebti SM, Turkson J, Wu X, Yang H, Yu H, Melino G. Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine. Cell Death Differ. 2018 11; 25(11):1885-1904. PMID: 30323273.
      Citations: 4     Fields:    Translation:Humans
    22. Tsao AS, Lindwasser OW, Adjei AA, Adusumilli PS, Beyers ML, Blumenthal GM, Bueno R, Burt BM, Carbone M, Dahlberg SE, de Perrot M, Fennell DA, Friedberg J, Gill RR, Gomez DR, Harpole DH, Hassan R, Hesdorffer M, Hirsch FR, Hmeljak J, Kindler HL, Korn EL, Liu G, Mansfield AS, Nowak AK, Pass HI, Peikert T, Rimner A, Robinson BWS, Rosenzweig KE, Rusch VW, Salgia R, Sepesi B, Simone CB, Sridhara R, Szlosarek P, Taioli E, Tsao MS, Yang H, Zauderer MG, Malik SM. Current and Future Management of Malignant Mesothelioma: A Consensus Report from the National Cancer Institute Thoracic Malignancy Steering Committee, International Association for the Study of Lung Cancer, and Mesothelioma Applied Research Foundation. J Thorac Oncol. 2018 11; 13(11):1655-1667. PMID: 30266660.
      Citations: 6     Fields:    Translation:Humans
    23. Mutti L, Peikert T, Robinson BWS, Scherpereel A, Tsao AS, de Perrot M, Woodard GA, Jablons DM, Wiens J, Hirsch FR, Yang H, Carbone M, Thomas A, Hassan R. Scientific Advances and New Frontiers in Mesothelioma Therapeutics. J Thorac Oncol. 2018 09; 13(9):1269-1283. PMID: 29966799.
      Citations: 16     Fields:    Translation:Humans
    24. Carbone M. Just a handful of publications can collect the prize. Nature. 2018 09; 561(7724):464. PMID: 30258141.
      Citations:    Fields:    Translation:Humans
    25. McCambridge AJ, Napolitano A, Mansfield AS, Fennell DA, Sekido Y, Nowak AK, Reungwetwattana T, Mao W, Pass HI, Carbone M, Yang H, Peikert T. Progress in the Management of Malignant Pleural Mesothelioma in 2017. J Thorac Oncol. 2018 05; 13(5):606-623. PMID: 29524617.
      Citations: 14     Fields:    Translation:Humans
    26. Carbone M, Guo Z, Mao W. Improving the Accuracy of Mesothelioma Diagnosis in China. J Thorac Oncol. 2017 08; 12(8):e132. PMID: 28748828.
      Citations: 1     Fields:    Translation:Humans
    27. Bononi A, Yang H, Giorgi C, Patergnani S, Pellegrini L, Su M, Xie G, Signorato V, Pastorino S, Morris P, Sakamoto G, Kuchay S, Gaudino G, Pass HI, Napolitano A, Pinton P, Jia W, Carbone M. Germline BAP1 mutations induce a Warburg effect. Cell Death Differ. 2017 10; 24(10):1694-1704. PMID: 28665402.
      Citations: 20     Fields:    Translation:HumansCells
    28. Bononi A, Giorgi C, Patergnani S, Larson D, Verbruggen K, Tanji M, Pellegrini L, Signorato V, Olivetto F, Pastorino S, Nasu M, Napolitano A, Gaudino G, Morris P, Sakamoto G, Ferris LK, Danese A, Raimondi A, Tacchetti C, Kuchay S, Pass HI, Affar EB, Yang H, Pinton P, Carbone M. BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation. Nature. 2017 06 22; 546(7659):549-553. PMID: 28614305.
      Citations: 55     Fields:    Translation:HumansCells
    29. Carbone M, Yang H. Mesothelioma: recent highlights. Ann Transl Med. 2017 Jun; 5(11):238. PMID: 28706906.
      Citations:    
    30. Chen Z, Gaudino G, Pass HI, Carbone M, Yang H. Diagnostic and prognostic biomarkers for malignant mesothelioma: an update. Transl Lung Cancer Res. 2017 Jun; 6(3):259-269. PMID: 28713671.
      Citations:    
    31. Pellegrini L, Xue J, Larson D, Pastorino S, Jube S, Forest KH, Saad-Jube ZS, Napolitano A, Pagano I, Negi VS, Bianchi ME, Morris P, Pass HI, Gaudino G, Carbone M, Yang H. HMGB1 targeting by ethyl pyruvate suppresses malignant phenotype of human mesothelioma. Oncotarget. 2017 Apr 04; 8(14):22649-22661. PMID: 28186988.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    32. Mao W, Zhang X, Guo Z, Gao Z, Pass HI, Yang H, Carbone M. Association of Asbestos Exposure With Malignant Mesothelioma Incidence in Eastern China. JAMA Oncol. 2017 04 01; 3(4):562-564. PMID: 27918607.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    33. Szymiczek A, Pastorino S, Larson D, Tanji M, Pellegrini L, Xue J, Li S, Giorgi C, Pinton P, Takinishi Y, Pass HI, Furuya H, Gaudino G, Napolitano A, Carbone M, Yang H. FTY720 inhibits mesothelioma growth in vitro and in a syngeneic mouse model. J Transl Med. 2017 03 15; 15(1):58. PMID: 28298211.
      Citations: 6     Fields:    Translation:AnimalsCells
    34. Guo Z, Carbone M, Zhang X, Su D, Sun W, Lou J, Gao Z, Shao D, Chen J, Zhang G, Hu J, Chen K, Wang F, Pass HI, Yu H, Napolitano A, Yang H, Mao W. Improving the Accuracy of Mesothelioma Diagnosis in China. J Thorac Oncol. 2017 04; 12(4):714-723. PMID: 28007630.
      Citations: 10     Fields:    Translation:Humans
    35. Yoshikawa Y, Emi M, Hashimoto-Tamaoki T, Ohmuraya M, Sato A, Tsujimura T, Hasegawa S, Nakano T, Nasu M, Pastorino S, Szymiczek A, Bononi A, Tanji M, Pagano I, Gaudino G, Napolitano A, Goparaju C, Pass HI, Yang H, Carbone M. High-density array-CGH with targeted NGS unmask multiple noncontiguous minute deletions on chromosome 3p21 in mesothelioma. Proc Natl Acad Sci U S A. 2016 11 22; 113(47):13432-13437. PMID: 27834213.
      Citations: 34     Fields:    Translation:HumansCells
    36. Carbone M, Shimizu D, Napolitano A, Tanji M, Pass HI, Yang H, Pastorino S. Positive nuclear BAP1 immunostaining helps differentiate non-small cell lung carcinomas from malignant mesothelioma. Oncotarget. 2016 Sep 13; 7(37):59314-59321. PMID: 27447750.
      Citations: 12     Fields:    Translation:HumansCells
    37. Napolitano A, Carbone M. Malignant Mesothelioma: Time to Translate? Trends Cancer. 2016 09; 2(9):467-474. PMID: 28603777.
      Citations: 4     Fields:    Translation:HumansAnimals
    38. Carbone M, Kanodia S, Chao A, Miller A, Wali A, Weissman D, Adjei A, Baumann F, Boffetta P, Buck B, de Perrot M, Dogan AU, Gavett S, Gualtieri A, Hassan R, Hesdorffer M, Hirsch FR, Larson D, Mao W, Masten S, Pass HI, Peto J, Pira E, Steele I, Tsao A, Woodard GA, Yang H, Malik S. Consensus Report of the 2015 Weinman International Conference on Mesothelioma. J Thorac Oncol. 2016 08; 11(8):1246-1262. PMID: 27453164.
      Citations: 37     Fields:    Translation:HumansPHPublic Health
    39. Zhang L, Shimizu D, Killeen JL, Honda SA, Lu D, Stanoyevitch A, Lin F, Wang B, Monuki ES, Carbone M. Serous carcinomatous component championed by heparin-binding EGF-like growth factor (HB-EGF) predisposing to metastasis and recurrence in stage I uterine malignant mixed mullerian tumor. Hum Pathol. 2016 07; 53:159-67. PMID: 26980026.
      Citations:    Fields:    Translation:Humans
    40. Ransohoff KJ, Jaju PD, Jaju PD, Tang JY, Carbone M, Leachman S, Sarin KY. Familial skin cancer syndromes: Increased melanoma risk. J Am Acad Dermatol. 2016 Mar; 74(3):423-34; quiz 435-6. PMID: 26892652.
      Citations: 6     Fields:    Translation:Humans
    41. Pass HI, Goparaju C, Espin-Garcia O, Donington J, Carbone M, Patel D, Chen Z, Feld R, Cho J, Gadgeel S, Wozniak A, Chachoua A, Leighl N, Tsao MS, de Perrot M, Xu W, Liu G. Plasma Biomarker Enrichment of Clinical Prognostic Indices in Malignant Pleural Mesothelioma. J Thorac Oncol. 2016 06; 11(6):900-9. PMID: 26903362.
      Citations: 5     Fields:    Translation:Humans
    42. Napolitano A, Antoine DJ, Pellegrini L, Baumann F, Pagano I, Pastorino S, Goparaju CM, Prokrym K, Canino C, Pass HI, Carbone M, Yang H. HMGB1 and Its Hyperacetylated Isoform are Sensitive and Specific Serum Biomarkers to Detect Asbestos Exposure and to Identify Mesothelioma Patients. Clin Cancer Res. 2016 06 15; 22(12):3087-96. PMID: 26733616.
      Citations: 40     Fields:    Translation:HumansCellsPHPublic Health
    43. Larson D, Powers A, Ambrosi JP, Tanji M, Napolitano A, Flores EG, Baumann F, Pellegrini L, Jennings CJ, Buck BJ, McLaurin BT, Merkler D, Robinson C, Morris P, Dogan M, Dogan AU, Pass HI, Pastorino S, Carbone M, Yang H. Investigating palygorskite's role in the development of mesothelioma in southern Nevada: Insights into fiber-induced carcinogenicity. J Toxicol Environ Health B Crit Rev. 2016; 19(5-6):213-230. PMID: 27705545.
      Citations: 6     Fields:    Translation:AnimalsCells
    44. Baumann F, Carbone M. Environmental risk of mesothelioma in the United States: An emerging concern-epidemiological issues. J Toxicol Environ Health B Crit Rev. 2016; 19(5-6):231-249. PMID: 27705543.
      Citations: 10     Fields:    Translation:HumansPHPublic Health
    45. Carbone M, Flores EG, Emi M, Johnson TA, Tsunoda T, Behner D, Hoffman H, Hesdorffer M, Nasu M, Napolitano A, Powers A, Minaai M, Baumann F, Bryant-Greenwood P, Lauk O, Kirschner MB, Weder W, Opitz I, Pass HI, Gaudino G, Pastorino S, Yang H. Combined Genetic and Genealogic Studies Uncover a Large BAP1 Cancer Syndrome Kindred Tracing Back Nine Generations to a Common Ancestor from the 1700s. PLoS Genet. 2015 Dec; 11(12):e1005633. PMID: 26683624.
      Citations: 32     Fields:    Translation:Humans
    46. Napolitano A, Carbone M. Concerns About Presence of a Wild-Type BAP1 Allele in Absence of Nuclear Protein Expression. JAMA Dermatol. 2015 Nov; 151(11):1265-6. PMID: 26559347.
      Citations:    Fields:    Translation:Humans
    47. Daou S, Hammond-Martel I, Mashtalir N, Barbour H, Gagnon J, Iannantuono NV, Nkwe NS, Motorina A, Pak H, Yu H, Wurtele H, Milot E, Mallette FA, Carbone M, Affar el B. The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer. J Biol Chem. 2015 Nov 27; 290(48):28643-63. PMID: 26416890.
      Citations: 23     Fields:    Translation:HumansCells
    48. Bononi A, Napolitano A, Pass HI, Yang H, Carbone M. Latest developments in our understanding of the pathogenesis of mesothelioma and the design of targeted therapies. Expert Rev Respir Med. 2015 Oct; 9(5):633-54. PMID: 26308799.
      Citations: 16     Fields:    Translation:Humans
    49. Croce A, Allegrina M, Rinaudo C, Gaudino G, Yang H, Carbone M. Numerous Iron-Rich Particles Lie on the Surface of Erionite Fibers from Rome (Oregon, USA) and Karlik (Cappadocia, Turkey). Microsc Microanal. 2015 Oct; 21(5):1341-7. PMID: 26286705.
      Citations: 4     Fields:    
    50. Klebe S, Driml J, Nasu M, Pastorino S, Zangiabadi A, Henderson D, Carbone M. BAP1 hereditary cancer predisposition syndrome: a case report and review of literature. Biomark Res. 2015; 3:14. PMID: 26140217.
      Citations:    
    51. Baumann F, Buck BJ, Metcalf RV, McLaurin BT, Merkler DJ, Carbone M. The Presence of Asbestos in the Natural Environment is Likely Related to Mesothelioma in Young Individuals and Women from Southern Nevada. J Thorac Oncol. 2015 May; 10(5):731-737. PMID: 25668121.
      Citations: 31     Fields:    Translation:HumansPHPublic Health
    52. Nasu M, Emi M, Pastorino S, Tanji M, Powers A, Luk H, Baumann F, Zhang YA, Gazdar A, Kanodia S, Tiirikainen M, Flores E, Gaudino G, Becich MJ, Pass HI, Yang H, Carbone M. High Incidence of Somatic BAP1 alterations in sporadic malignant mesothelioma. J Thorac Oncol. 2015 Apr; 10(4):565-76. PMID: 25658628.
      Citations: 66     Fields:    Translation:HumansCells
    53. Carbone M, Gaudino G, Yang H. Recent insights emerging from malignant mesothelioma genome sequencing. J Thorac Oncol. 2015 Mar; 10(3):409-11. PMID: 25695218.
      Citations: 4     Fields:    Translation:Humans
    54. Hoffmann PR, Panigada M, Soprana E, Terry F, Bandar IS, Napolitano A, Rose AH, Hoffmann FW, Ndhlovu LC, Belcaid M, Moise L, De Groot AS, Carbone M, Gaudino G, Matsui T, Siccardi A, Bertino P. Preclinical development of HIvax: Human survivin highly immunogenic vaccines. Hum Vaccin Immunother. 2015; 11(7):1585-95. PMID: 26042612.
      Citations: 9     Fields:    Translation:HumansCellsPHPublic Health
    55. Guo G, Chmielecki J, Goparaju C, Heguy A, Dolgalev I, Carbone M, Seepo S, Meyerson M, Pass HI. Whole-exome sequencing reveals frequent genetic alterations in BAP1, NF2, CDKN2A, and CUL1 in malignant pleural mesothelioma. Cancer Res. 2015 Jan 15; 75(2):264-9. PMID: 25488749.
      Citations: 68     Fields:    Translation:Humans
    56. Comertpay S, Pastorino S, Tanji M, Mezzapelle R, Strianese O, Napolitano A, Baumann F, Weigel T, Friedberg J, Sugarbaker P, Krausz T, Wang E, Powers A, Gaudino G, Kanodia S, Pass HI, Parsons BL, Yang H, Carbone M. Evaluation of clonal origin of malignant mesothelioma. J Transl Med. 2014 Dec 04; 12:301. PMID: 25471750.
      Citations: 23     Fields:    Translation:Humans
    57. Gaudino G, Yang H, Carbone M. HGF/Met Signaling Is a Key Player in Malignant Mesothelioma Carcinogenesis. Biomedicines. 2014 Nov 14; 2(4):327-344. PMID: 28548074.
      Citations:    
    58. Baumann F, Flores E, Napolitano A, Kanodia S, Taioli E, Pass H, Yang H, Carbone M. Mesothelioma patients with germline BAP1 mutations have 7-fold improved long-term survival. Carcinogenesis. 2015 Jan; 36(1):76-81. PMID: 25380601.
      Citations: 48     Fields:    Translation:Humans
    59. Zhang L, Comertpay S, Shimizu D, DeMay RM, Carbone M, Honda SA, Eaves JM. Axillary metaplastic breast carcinoma with ipsilateral pectoral invasive ductal carcinoma: an unusual presentation. Case Rep Oncol Med. 2014; 2014:938509. PMID: 25364575.
      Citations:    
    60. Yahirun JJ, Hamplová D. CHILDREN'S UNION STATUS AND CONTACT WITH MOTHERS: A CROSS-NATIONAL STUDY. Demogr Res. 2014 Jan-Jun; 30:1413-1444. PMID: 32206570.
      Citations:    
    61. Yahirun JJ, Hamplová D. CHILDREN'S UNION STATUS AND CONTACT WITH MOTHERS: A CROSS-NATIONAL STUDY. Demogr Res. 2014 Jan-Jun; 30:1413-1444. PMID: 12459734.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    62. Yahirun JJ, Hamplová D. CHILDREN'S UNION STATUS AND CONTACT WITH MOTHERS: A CROSS-NATIONAL STUDY. Demogr Res. 2014 Jan-Jun; 30:1413-1444. PMID: 26134238.
      Citations:    Fields:    Translation:HumansPHPublic Health
    63. Yahirun JJ, Hamplová D. CHILDREN'S UNION STATUS AND CONTACT WITH MOTHERS: A CROSS-NATIONAL STUDY. Demogr Res. 2014 Jan-Jun; 30:1413-1444. PMID: 17251920.
      Citations: 51     Fields:    Translation:HumansPHPublic Health
    64. Rose AH, Bertino P, Hoffmann FW, Gaudino G, Carbone M, Hoffmann PR. Increasing dietary selenium elevates reducing capacity and ERK activation associated with accelerated progression of select mesothelioma tumors. Am J Pathol. 2014 Apr; 184(4):1041-1049. PMID: 24492200.
      Citations: 6     Fields:    Translation:AnimalsCells
    65. Qi F, Okimoto G, Jube S, Napolitano A, Pass HI, Laczko R, Demay RM, Khan G, Tiirikainen M, Rinaudo C, Croce A, Yang H, Gaudino G, Carbone M. Continuous exposure to chrysotile asbestos can cause transformation of human mesothelial cells via HMGB1 and TNF-a signaling. Am J Pathol. 2013 Nov; 183(5):1654-66. PMID: 24160326.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    66. Baumann F, Ambrosi JP, Carbone M. Asbestos is not just asbestos: an unrecognised health hazard. Lancet Oncol. 2013 Jun; 14(7):576-8. PMID: 23725699.
      Citations: 45     Fields:    Translation:HumansPHPublic Health
    67. Carbone M, Yang H, Pass HI, Krausz T, Testa JR, Gaudino G. BAP1 and cancer. Nat Rev Cancer. 2013 03; 13(3):153-9. PMID: 23550303.
      Citations: 171     Fields:    Translation:Humans
    68. Bertino P, Panigada M, Soprana E, Bianchi V, Bertilaccio S, Sanvito F, Rose AH, Yang H, Gaudino G, Hoffmann PR, Siccardi A, Carbone M. Fowlpox-based survivin vaccination for malignant mesothelioma therapy. Int J Cancer. 2013 Aug 01; 133(3):612-23. PMID: 23335100.
      Citations: 13     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    69. Pass HI, Levin SM, Harbut MR, Melamed J, Chiriboga L, Donington J, Huflejt M, Carbone M, Chia D, Goodglick L, Goodman GE, Thornquist MD, Liu G, de Perrot M, Tsao MS, Goparaju C. Fibulin-3 as a blood and effusion biomarker for pleural mesothelioma. N Engl J Med. 2012 Oct 11; 367(15):1417-27. PMID: 23050525.
      Citations: 101     Fields:    Translation:HumansPHPublic Health
    70. Ostroff RM, Mehan MR, Stewart A, Ayers D, Brody EN, Williams SA, Levin S, Black B, Harbut M, Carbone M, Goparaju C, Pass HI. Early detection of malignant pleural mesothelioma in asbestos-exposed individuals with a noninvasive proteomics-based surveillance tool. PLoS One. 2012; 7(10):e46091. PMID: 23056237.
      Citations: 44     Fields:    Translation:HumansPHPublic Health
    71. Carbone M, Ferris LK, Baumann F, Napolitano A, Lum CA, Flores EG, Gaudino G, Powers A, Bryant-Greenwood P, Krausz T, Hyjek E, Tate R, Friedberg J, Weigel T, Pass HI, Yang H. BAP1 cancer syndrome: malignant mesothelioma, uveal and cutaneous melanoma, and MBAITs. J Transl Med. 2012 Aug 30; 10:179. PMID: 22935333.
      Citations: 85     Fields:    Translation:Humans
    72. Rivera Z, Ferrone S, Wang X, Jube S, Yang H, Pass HI, Kanodia S, Gaudino G, Carbone M. CSPG4 as a target of antibody-based immunotherapy for malignant mesothelioma. Clin Cancer Res. 2012 Oct 01; 18(19):5352-63. PMID: 22893632.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    73. Jube S, Rivera ZS, Bianchi ME, Powers A, Wang E, Pagano I, Pass HI, Gaudino G, Carbone M, Yang H. Cancer cell secretion of the DAMP protein HMGB1 supports progression in malignant mesothelioma. Cancer Res. 2012 Jul 01; 72(13):3290-301. PMID: 22552293.
      Citations: 91     Fields:    Translation:HumansAnimalsCells
    74. Carbone M, Ly BH, Dodson RF, Pagano I, Morris PT, Dogan UA, Gazdar AF, Pass HI, Yang H. Malignant mesothelioma: facts, myths, and hypotheses. J Cell Physiol. 2012 Jan; 227(1):44-58. PMID: 21412769.
      Citations: 121     Fields:    Translation:Humans
    75. Carbone M, Yang H. Molecular pathways: targeting mechanisms of asbestos and erionite carcinogenesis in mesothelioma. Clin Cancer Res. 2012 Feb 01; 18(3):598-604. PMID: 22065079.
      Citations: 65     Fields:    Translation:Humans
    76. Qi F, Carbone M, Yang H, Gaudino G. Simian virus 40 transformation, malignant mesothelioma and brain tumors. Expert Rev Respir Med. 2011 Oct; 5(5):683-97. PMID: 21955238.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    77. Testa JR, Cheung M, Pei J, Below JE, Tan Y, Sementino E, Cox NJ, Dogan AU, Pass HI, Trusa S, Hesdorffer M, Nasu M, Powers A, Rivera Z, Comertpay S, Tanji M, Gaudino G, Yang H, Carbone M. Germline BAP1 mutations predispose to malignant mesothelioma. Nat Genet. 2011 Aug 28; 43(10):1022-5. PMID: 21874000.
      Citations: 283     Fields:    Translation:HumansPHPublic Health
    78. Carbone M, Baris YI, Bertino P, Brass B, Comertpay S, Dogan AU, Gaudino G, Jube S, Kanodia S, Partridge CR, Pass HI, Rivera ZS, Steele I, Tuncer M, Way S, Yang H, Miller A. Erionite exposure in North Dakota and Turkish villages with mesothelioma. Proc Natl Acad Sci U S A. 2011 Aug 16; 108(33):13618-23. PMID: 21788493.
      Citations: 46     Fields:    Translation:HumansPHPublic Health
    79. Nasu M, Carbone M, Gaudino G, Ly BH, Bertino P, Shimizu D, Morris P, Pass HI, Yang H. Ranpirnase Interferes with NF-?B Pathway and MMP9 Activity, Inhibiting Malignant Mesothelioma Cell Invasiveness and Xenograft Growth. Genes Cancer. 2011 May; 2(5):576-84. PMID: 21901170.
      Citations:    
    80. Altomare DA, Menges CW, Xu J, Pei J, Zhang L, Tadevosyan A, Neumann-Domer E, Liu Z, Carbone M, Chudoba I, Klein-Szanto AJ, Testa JR. Losses of both products of the Cdkn2a/Arf locus contribute to asbestos-induced mesothelioma development and cooperate to accelerate tumorigenesis. PLoS One. 2011 Apr 19; 6(4):e18828. PMID: 21526190.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    81. Shukla A, Hillegass JM, MacPherson MB, Beuschel SL, Vacek PM, Butnor KJ, Pass HI, Carbone M, Testa JR, Heintz NH, Mossman BT. ERK2 is essential for the growth of human epithelioid malignant mesotheliomas. Int J Cancer. 2011 Sep 01; 129(5):1075-86. PMID: 21710492.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    82. Shukla A, Hillegass JM, MacPherson MB, Beuschel SL, Vacek PM, Pass HI, Carbone M, Testa JR, Mossman BT. Blocking of ERK1 and ERK2 sensitizes human mesothelioma cells to doxorubicin. Mol Cancer. 2010 Dec 15; 9:314. PMID: 21159167.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    83. Hillegass JM, Blumen SR, Cheng K, MacPherson MB, Alexeeva V, Lathrop SA, Beuschel SL, Steinbacher JL, Butnor KJ, Ramos-Niño ME, Shukla A, James TA, Weiss DJ, Taatjes DJ, Pass HI, Carbone M, Landry CC, Mossman BT. Increased efficacy of doxorubicin delivered in multifunctional microparticles for mesothelioma therapy. Int J Cancer. 2011 Jul 01; 129(1):233-44. PMID: 20830711.
      Citations: 16     Fields:    Translation:HumansAnimals
    84. Flores RM, Riedel E, Donington JS, Alago W, Ihekweazu U, Krug L, Rosenzweig K, Adusumilli PS, Carbone M, Pass HI. Frequency of use and predictors of cancer-directed surgery in the management of malignant pleural mesothelioma in a community-based (Surveillance, Epidemiology, and End Results [SEER]) population. J Thorac Oncol. 2010 Oct; 5(10):1649-54. PMID: 20871264.
      Citations: 24     Fields:    Translation:Humans
    85. Zhang L, Qi F, Gaudino G, Strianese O, Yang H, Morris P, Pass HI, Nerurkar VR, Bocchetta M, Carbone M. Tissue Tropism of SV40 Transformation of Human Cells: Role of the Viral Regulatory Region and of Cellular Oncogenes. Genes Cancer. 2010 Oct; 1(10):1008-20. PMID: 21779427.
      Citations:    
    86. Hillegass JM, Shukla A, Lathrop SA, MacPherson MB, Beuschel SL, Butnor KJ, Testa JR, Pass HI, Carbone M, Steele C, Mossman BT. Inflammation precedes the development of human malignant mesotheliomas in a SCID mouse xenograft model. Ann N Y Acad Sci. 2010 Aug; 1203:7-14. PMID: 20716277.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    87. Yang H, Rivera Z, Jube S, Nasu M, Bertino P, Goparaju C, Franzoso G, Lotze MT, Krausz T, Pass HI, Bianchi ME, Carbone M. Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation. Proc Natl Acad Sci U S A. 2010 Jul 13; 107(28):12611-6. PMID: 20616036.
      Citations: 103     Fields:    Translation:HumansAnimalsCells
    88. Demaria S, Pikarsky E, Karin M, Coussens LM, Chen YC, El-Omar EM, Trinchieri G, Dubinett SM, Mao JT, Szabo E, Krieg A, Weiner GJ, Fox BA, Coukos G, Wang E, Abraham RT, Carbone M, Lotze MT. Cancer and inflammation: promise for biologic therapy. J Immunother. 2010 May; 33(4):335-51. PMID: 20386472.
      Citations: 108     Fields:    Translation:HumansAnimals
    89. Pass HI, Goparaju C, Ivanov S, Donington J, Carbone M, Hoshen M, Cohen D, Chajut A, Rosenwald S, Dan H, Benjamin S, Aharonov R. hsa-miR-29c* is linked to the prognosis of malignant pleural mesothelioma. Cancer Res. 2010 Mar 01; 70(5):1916-24. PMID: 20160038.
      Citations: 44     Fields:    Translation:HumansCells
    90. Carbone M. Feasibility of immunotherapy for lymphangioleiomyomatosis. Am J Pathol. 2009 Dec; 175(6):2252-4. PMID: 19893040.
      Citations: 2     Fields:    Translation:Humans
    91. Shukla A, Bosenberg MW, MacPherson MB, Butnor KJ, Heintz NH, Pass HI, Carbone M, Testa JR, Mossman BT. Activated cAMP response element binding protein is overexpressed in human mesotheliomas and inhibits apoptosis. Am J Pathol. 2009 Nov; 175(5):2197-206. PMID: 19815709.
      Citations: 27     Fields:    Translation:HumansCells
    92. Altomare DA, Menges CW, Pei J, Zhang L, Skele-Stump KL, Carbone M, Kane AB, Testa JR. Activated TNF-alpha/NF-kappaB signaling via down-regulation of Fas-associated factor 1 in asbestos-induced mesotheliomas from Arf knockout mice. Proc Natl Acad Sci U S A. 2009 Mar 03; 106(9):3420-5. PMID: 19223589.
      Citations: 38     Fields:    Translation:AnimalsCells
    93. Ivanov SV, Miller J, Lucito R, Tang C, Ivanova AV, Pei J, Carbone M, Cruz C, Beck A, Webb C, Nonaka D, Testa JR, Pass HI. Genomic events associated with progression of pleural malignant mesothelioma. Int J Cancer. 2009 Feb 01; 124(3):589-99. PMID: 18973227.
      Citations: 20     Fields:    Translation:Humans
    94. Yang H, Nasu M, Strianese O, Rivera Z, Luecke L, Carbone M. The legacy of "miracle mineral": asbestos and cancer. Hawaii Med J. 2009 Jan-Feb; 68(1):18-20. PMID: 19365925.
      Citations:    Fields:    Translation:Humans
    95. Pass HI, Carbone M. Current status of screening for malignant pleural mesothelioma. Semin Thorac Cardiovasc Surg. 2009; 21(2):97-104. PMID: 19822280.
      Citations: 18     Fields:    Translation:HumansPHPublic Health
    96. Bertino P, Carbone M, Pass H. Chemotherapy of malignant pleural mesothelioma. Expert Opin Pharmacother. 2009 Jan; 10(1):99-107. PMID: 19236184.
      Citations: 3     Fields:    Translation:Humans
    97. Carbone M, Pannuti A, Zhang L, Testa JR, Bocchetta M. A novel mechanism of late gene silencing drives SV40 transformation of human mesothelial cells. Cancer Res. 2008 Nov 15; 68(22):9488-96. PMID: 19010924.
      Citations: 16     Fields:    Translation:HumansCells
    98. Yang H, Testa JR, Carbone M. Mesothelioma epidemiology, carcinogenesis, and pathogenesis. Curr Treat Options Oncol. 2008 Jun; 9(2-3):147-57. PMID: 18709470.
      Citations: 79     Fields:    Translation:HumansCells
    99. Pass HI, Brewer GJ, Dick R, Carbone M, Merajver S. A phase II trial of tetrathiomolybdate after surgery for malignant mesothelioma: final results. Ann Thorac Surg. 2008 Aug; 86(2):383-9; discussion 390. PMID: 18640301.
      Citations: 19     Fields:    Translation:HumansCTClinical Trials
    100. Rivera Z, Strianese O, Bertino P, Yang H, Pass H, Carbone M. The relationship between simian virus 40 and mesothelioma. Curr Opin Pulm Med. 2008 Jul; 14(4):316-21. PMID: 18520265.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    101. Beck AK, Pass HI, Carbone M, Yang H. Ranpirnase as a potential antitumor ribonuclease treatment for mesothelioma and other malignancies. Future Oncol. 2008 Jun; 4(3):341-9. PMID: 18518759.
      Citations: 11     Fields:    Translation:HumansAnimals
    102. Bocchetta M, Eliasz S, De Marco MA, Rudzinski J, Zhang L, Carbone M. The SV40 large T antigen-p53 complexes bind and activate the insulin-like growth factor-I promoter stimulating cell growth. Cancer Res. 2008 Feb 15; 68(4):1022-9. PMID: 18281476.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    103. Flores RM, Pass HI, Seshan VE, Dycoco J, Zakowski M, Carbone M, Bains MS, Rusch VW. Extrapleural pneumonectomy versus pleurectomy/decortication in the surgical management of malignant pleural mesothelioma: results in 663 patients. J Thorac Cardiovasc Surg. 2008 Mar; 135(3):620-6, 626.e1-3. PMID: 18329481.
      Citations: 130     Fields:    Translation:Humans
    104. Bocchetta M, Carbone M. SV40 Tag/p53 complexes actively promote malignant cell growth of human mesothelial cells. Cell Oncol. 2008; 30(5):455. PMID: 18853526.
      Citations: 1     Fields:    Translation:HumansCells
    105. Pass HI, Wali A, Tang N, Ivanova A, Ivanov S, Harbut M, Carbone M, Allard J. Soluble mesothelin-related peptide level elevation in mesothelioma serum and pleural effusions. Ann Thorac Surg. 2008 Jan; 85(1):265-72; discussion 272. PMID: 18154821.
      Citations: 41     Fields:    Translation:Humans
    106. Ramos-Nino ME, Blumen SR, Sabo-Attwood T, Pass H, Carbone M, Testa JR, Altomare DA, Mossman BT. HGF mediates cell proliferation of human mesothelioma cells through a PI3K/MEK5/Fra-1 pathway. Am J Respir Cell Mol Biol. 2008 Feb; 38(2):209-17. PMID: 17872495.
      Citations: 30     Fields:    Translation:HumansCells
    107. Carbone M, Strianese O, Theos K, Yang H. Mesothelioma. Hawaii Med J. 2007 Feb; 66(2):48-50. PMID: 17393919.
      Citations:    Fields:    Translation:Humans
    108. Kroczynska B, Cutrone R, Bocchetta M, Yang H, Elmishad AG, Vacek P, Ramos-Nino M, Mossman BT, Pass HI, Carbone M. Crocidolite asbestos and SV40 are cocarcinogens in human mesothelial cells and in causing mesothelioma in hamsters. Proc Natl Acad Sci U S A. 2006 Sep 19; 103(38):14128-33. PMID: 16966607.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    109. Kroczynska B, Carbone M. Cross reactivity between many anti-human antibodies for their hamster homologs provide the tools to study the signal transduction pathway activated by asbestos and SV40 in the malignant mesothelioma model. Mol Carcinog. 2006 Jul; 45(7):537-42. PMID: 16649249.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    110. Ramos-Nino ME, Testa JR, Altomare DA, Pass HI, Carbone M, Bocchetta M, Mossman BT. Cellular and molecular parameters of mesothelioma. J Cell Biochem. 2006 Jul 01; 98(4):723-34. PMID: 16795078.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    111. Yang H, Bocchetta M, Kroczynska B, Elmishad AG, Chen Y, Liu Z, Bubici C, Mossman BT, Pass HI, Testa JR, Franzoso G, Carbone M. TNF-alpha inhibits asbestos-induced cytotoxicity via a NF-kappaB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis. Proc Natl Acad Sci U S A. 2006 Jul 05; 103(27):10397-10402. PMID: 16798876.
      Citations: 93     Fields:    Translation:HumansCells
    112. Dogan AU, Baris YI, Dogan M, Emri S, Steele I, Elmishad AG, Carbone M. Genetic predisposition to fiber carcinogenesis causes a mesothelioma epidemic in Turkey. Cancer Res. 2006 May 15; 66(10):5063-8. PMID: 16707428.
      Citations: 37     Fields:    Translation:HumansPHPublic Health
    113. Rdzanek M, Fresco R, Pass HI, Carbone M. Spindle cell tumors of the pleura: differential diagnosis. Semin Diagn Pathol. 2006 Feb; 23(1):44-55. PMID: 17044195.
      Citations: 5     Fields:    Translation:Humans
    114. Carbone M, Bedrossian CW. The pathogenesis of mesothelioma. Semin Diagn Pathol. 2006 Feb; 23(1):56-60. PMID: 17044196.
      Citations: 20     Fields:    Translation:HumansAnimals
    115. Carbone M, Pass HI. Evolving aspects of mesothelioma carcinogenesis: SV40 and genetic predisposition. J Thorac Oncol. 2006 Feb; 1(2):169-71. PMID: 17409848.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    116. Cutrone R, Lednicky J, Dunn G, Rizzo P, Bocchetta M, Chumakov K, Minor P, Carbone M. Some oral poliovirus vaccines were contaminated with infectious SV40 after 1961. Cancer Res. 2005 Nov 15; 65(22):10273-9. PMID: 16288015.
      Citations: 32     Fields:    Translation:AnimalsCellsPHPublic Health
    117. Carbone M, Rdzanek MA, Rudzinski JJ, De Marco MA, Bocchetta M, Ramos Niño M, Mossman B, Pass HI. SV40 detection in human tumor specimens. Cancer Res. 2005 Nov 01; 65(21):10120-1. PMID: 16267039.
      Citations: 8     Fields:    Translation:HumansCells
    118. Pass HI, Lott D, Lonardo F, Harbut M, Liu Z, Tang N, Carbone M, Webb C, Wali A. Asbestos exposure, pleural mesothelioma, and serum osteopontin levels. N Engl J Med. 2005 Oct 13; 353(15):1564-73. PMID: 16221779.
      Citations: 99     Fields:    Translation:HumansPHPublic Health
    119. Suzuki M, Toyooka S, Shivapurkar N, Shigematsu H, Miyajima K, Takahashi T, Stastny V, Zern AL, Fujisawa T, Pass HI, Carbone M, Gazdar AF. Aberrant methylation profile of human malignant mesotheliomas and its relationship to SV40 infection. Oncogene. 2005 Feb 10; 24(7):1302-8. PMID: 15592515.
      Citations: 15     Fields:    Translation:HumansCells
    120. Tanvetyanon T, Elmishad AG, Carbone M. Development of malignant mesothelioma during treatment for prolymphocytic leukemia: is asbestos or simian virus 40 a link? Anticancer Res. 2005 Jan-Feb; 25(1B):429-33. PMID: 15816607.
      Citations:    Fields:    Translation:HumansCells
    121. Wali A, Morin PJ, Hough CD, Lonardo F, Seya T, Carbone M, Pass HI. Identification of intelectin overexpression in malignant pleural mesothelioma by serial analysis of gene expression (SAGE). Lung Cancer. 2005 Apr; 48(1):19-29. PMID: 15777968.
      Citations: 16     Fields:    Translation:HumansCells
    122. Carbone M, Pass HI. Multistep and multifactorial carcinogenesis: when does a contributing factor become a carcinogen? Semin Cancer Biol. 2004 Dec; 14(6):399-405. PMID: 15489132.
      Citations: 1     Fields:    Translation:HumansAnimals
    123. Pass HI, Bocchetta M, Carbone M. Evidence of an important role for SV40 in mesothelioma. Thorac Surg Clin. 2004 Nov; 14(4):489-95. PMID: 15559055.
      Citations: 4     Fields:    Translation:HumansCells
    124. Hurtuk MG, Carbone M. A cytokeratin- and calretinin-negative staining sarcomatoid malignant mesothelioma. Anticancer Res. 2004 Sep-Oct; 24(5B):3097-102. PMID: 15510595.
      Citations:    Fields:    Translation:Humans
    125. Bocchetta M, Carbone M. Epidemiology and molecular pathology at crossroads to establish causation: molecular mechanisms of malignant transformation. Oncogene. 2004 Aug 23; 23(38):6484-91. PMID: 15322519.
      Citations: 4     Fields:    Translation:Humans
    126. Carbone M, Klein G, Gruber J, Wong M. Modern criteria to establish human cancer etiology. Cancer Res. 2004 Aug 01; 64(15):5518-24. PMID: 15289363.
      Citations: 21     Fields:    Translation:HumansCells
    127. Pass HI, Vogelzang N, Hahn S, Carbone M. Malignant pleural mesothelioma. Curr Probl Cancer. 2004 May-Jun; 28(3):93-174. PMID: 15197388.
      Citations: 21     Fields:    Translation:Humans
    128. Carbone M, Rdzanek MA. Pathogenesis of malignant mesothelioma. Clin Lung Cancer. 2004 Apr; 5 Suppl 2:S46-50. PMID: 15117424.
      Citations: 6     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    129. Pass HI, Liu Z, Wali A, Bueno R, Land S, Lott D, Siddiq F, Lonardo F, Carbone M, Draghici S. Gene expression profiles predict survival and progression of pleural mesothelioma. Clin Cancer Res. 2004 Feb 01; 10(3):849-59. PMID: 14871960.
      Citations: 41     Fields:    Translation:Humans
    130. Gazdar AF, Carbone M. Molecular pathogenesis of malignant mesothelioma and its relationship to simian virus 40. Clin Lung Cancer. 2003 Nov; 5(3):177-81. PMID: 14667274.
      Citations: 20     Fields:    Translation:HumansCells
    131. Carbone M, Rudzinski J, Bocchetta M. High throughput testing of the SV40 Large T antigen binding to cellular p53 identifies putative drugs for the treatment of SV40-related cancers. Virology. 2003 Oct 25; 315(2):409-14. PMID: 14585344.
      Citations: 4     Fields:    Translation:HumansCells
    132. Carbone M, Burck C, Rdzanek M, Rudzinski J, Cutrone R, Bocchetta M. Different susceptibility of human mesothelial cells to polyomavirus infection and malignant transformation. Cancer Res. 2003 Oct 01; 63(19):6125-9. PMID: 14559789.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    133. Carbone M, Bocchetta M, Cristaudo A, Emri S, Gazdar A, Jasani B, Lednicky J, Miele L, Mutti L, Pass HI, Ramael M, Rizzo P, Testa JR, Weggen S, Yeung A. SV40 and human brain tumors. Int J Cancer. 2003 Aug 10; 106(1):140-2; author reply 143-5. PMID: 12794770.
      Citations: 6     Fields:    Translation:HumansCells
    134. Bocchetta M, Miele L, Pass HI, Carbone M. Notch-1 induction, a novel activity of SV40 required for growth of SV40-transformed human mesothelial cells. Oncogene. 2003 Jan 09; 22(1):81-9. PMID: 12527910.
      Citations: 34     Fields:    Translation:HumansCells
    135. Carbone M, Rizzo P, Powers A, Bocchetta M, Fresco R, Krausz T. Molecular analyses, morphology and immunohistochemistry together differentiate pleural synovial sarcomas from mesotheliomas: clinical implications. Anticancer Res. 2002 Nov-Dec; 22(6B):3443-8. PMID: 12552937.
      Citations: 3     Fields:    Translation:HumansCells
    136. Powers A, Carbone M. The role of environmental carcinogens, viruses and genetic predisposition in the pathogenesis of mesothelioma. . 2002 Jul-Aug; 1(4):348-53. PMID: 12432244.
      Citations:    
    137. Toyooka S, Carbone M, Toyooka KO, Bocchetta M, Shivapurkar N, Minna JD, Gazdar AF. Progressive aberrant methylation of the RASSF1A gene in simian virus 40 infected human mesothelial cells. Oncogene. 2002 Jun 20; 21(27):4340-4. PMID: 12082623.
      Citations: 15     Fields:    Translation:HumansCells
    138. Emri S, Demir A, Dogan M, Akay H, Bozkurt B, Carbone M, Baris I. Lung diseases due to environmental exposures to erionite and asbestos in Turkey. Toxicol Lett. 2002 Feb 28; 127(1-3):251-7. PMID: 12052665.
      Citations: 15     Fields:    Translation:HumansPHPublic Health
    139. Foddis R, De Rienzo A, Broccoli D, Bocchetta M, Stekala E, Rizzo P, Tosolini A, Grobelny JV, Jhanwar SC, Pass HI, Testa JR, Carbone M. SV40 infection induces telomerase activity in human mesothelial cells. Oncogene. 2002 Feb 21; 21(9):1434-42. PMID: 11857086.
      Citations: 24     Fields:    Translation:HumansCells
    140. Carbone M, Pass HI. Re: Debate on the link between SV40 and human cancer continues. J Natl Cancer Inst. 2002 Feb 06; 94(3):229-30. PMID: 11830615.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    141. Carbone M, Kratzke RA, Testa JR. The pathogenesis of mesothelioma. Semin Oncol. 2002 Feb; 29(1):2-17. PMID: 11836664.
      Citations: 72     Fields:    Translation:HumansAnimalsCellsPHPublic Health
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    RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

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