RCMI Coordinating Center (RCMI CC) Header Logo

Connection

John Zhang to Blood-Brain Barrier

This is a "connection" page, showing publications John Zhang has written about Blood-Brain Barrier.
Connection Strength

6.109
  1. Okada T, Suzuki H, Travis ZD, Altay O, Tang J, Zhang JH. SPARC Aggravates Blood-Brain Barrier Disruption via Integrin aV?3/MAPKs/MMP-9 Signaling Pathway after Subarachnoid Hemorrhage. Oxid Med Cell Longev. 2021; 2021:9739977.
    View in: PubMed
    Score: 0.645
  2. Liang H, Matei N, McBride DW, Xu Y, Tang J, Luo B, Zhang JH. Activation of TGR5 protects blood brain barrier via the BRCA1/Sirt1 pathway after middle cerebral artery occlusion in rats. J Biomed Sci. 2020 May 08; 27(1):61.
    View in: PubMed
    Score: 0.581
  3. Zhu Q, Enkhjargal B, Huang L, Zhang T, Sun C, Xie Z, Wu P, Mo J, Tang J, Xie Z, Zhang JH. Aggf1 attenuates neuroinflammation and BBB disruption via PI3K/Akt/NF-?B pathway after subarachnoid hemorrhage in rats. J Neuroinflammation. 2018 Jun 09; 15(1):178.
    View in: PubMed
    Score: 0.509
  4. Shi X, Doycheva DM, Xu L, Tang J, Yan M, Zhang JH. Sestrin2 induced by hypoxia inducible factor1 alpha protects the blood-brain barrier via inhibiting VEGF after severe hypoxic-ischemic injury in neonatal rats. Neurobiol Dis. 2016 Nov; 95:111-21.
    View in: PubMed
    Score: 0.446
  5. Chen Y, Zhang Y, Tang J, Liu F, Hu Q, Luo C, Tang J, Feng H, Zhang JH. Norrin protected blood-brain barrier via frizzled-4/?-catenin pathway after subarachnoid hemorrhage in rats. Stroke. 2015 Feb; 46(2):529-36.
    View in: PubMed
    Score: 0.401
  6. Hasegawa Y, Suzuki H, Altay O, Chen H, Zhang JH. Treatment with sodium orthovanadate reduces blood-brain barrier disruption via phosphatase and tensin homolog deleted on chromosome 10 (PTEN) phosphorylation in experimental subarachnoid hemorrhage. J Neurosci Res. 2012 Mar; 90(3):691-7.
    View in: PubMed
    Score: 0.325
  7. Suzuki H, Hasegawa Y, Ayer R, Sugawara T, Chen W, Sozen T, Kanamaru K, Taki W, Zhang JH. Effects of recombinant osteopontin on blood-brain barrier disruption after subarachnoid hemorrhage in rats. Acta Neurochir Suppl. 2011; 111:231-6.
    View in: PubMed
    Score: 0.304
  8. Suzuki H, Hasegawa Y, Kanamaru K, Zhang JH. Mechanisms of osteopontin-induced stabilization of blood-brain barrier disruption after subarachnoid hemorrhage in rats. Stroke. 2010 Aug; 41(8):1783-90.
    View in: PubMed
    Score: 0.294
  9. Yatsushige H, Ostrowski RP, Tsubokawa T, Colohan A, Zhang JH. Role of c-Jun N-terminal kinase in early brain injury after subarachnoid hemorrhage. J Neurosci Res. 2007 May 15; 85(7):1436-48.
    View in: PubMed
    Score: 0.236
  10. Yuan Y, He Q, Yang X, Flores JJ, Huang L, Luo X, Zhang X, Zhang Z, Li R, Gu L, Dong S, Zhu S, Yi K, Han M, Wu L, Zhou Y, Zhang JH, Xie Z, Tang J. Mitochondrial ferritin upregulation reduced oxidative stress and blood-brain-barrier disruption by maintaining cellular iron homeostasis in a neonatal rat model of germinal matrix hemorrhage. Exp Neurol. 2024 Apr; 374:114703.
    View in: PubMed
    Score: 0.188
  11. He W, Lu Q, Sherchan P, Huang L, Hu X, Zhang JH, Dai H, Tang J. Activation of Frizzled-7 attenuates blood-brain barrier disruption through Dvl/?-catenin/WISP1 signaling pathway after intracerebral hemorrhage in mice. Fluids Barriers CNS. 2021 Sep 26; 18(1):44.
    View in: PubMed
    Score: 0.160
  12. Wang Y, Zhang JH, Sheng J, Shao A. Immunoreactive Cells After Cerebral Ischemia. Front Immunol. 2019; 10:2781.
    View in: PubMed
    Score: 0.141
  13. Akyol O, Sherchan P, Yilmaz G, Reis C, Ho WM, Wang Y, Huang L, Solaroglu I, Zhang JH. Neurotrophin-3 provides neuroprotection via TrkC receptor dependent pErk5 activation in a rat surgical brain injury model. Exp Neurol. 2018 09; 307:82-89.
    View in: PubMed
    Score: 0.127
  14. Fan R, Enkhjargal B, Camara R, Yan F, Gong L, Tang J, Chen Y, Zhang JH. Critical role of EphA4 in early brain injury after subarachnoid hemorrhage in rat. Exp Neurol. 2017 10; 296:41-48.
    View in: PubMed
    Score: 0.119
  15. Jiang B, Li L, Chen Q, Tao Y, Yang L, Zhang B, Zhang JH, Feng H, Chen Z, Tang J, Zhu G. Role of Glibenclamide in Brain Injury After Intracerebral Hemorrhage. Transl Stroke Res. 2017 04; 8(2):183-193.
    View in: PubMed
    Score: 0.114
  16. Zhao H, Zhang X, Dai Z, Feng Y, Li Q, Zhang JH, Liu X, Chen Y, Feng H. P2X7 Receptor Suppression Preserves Blood-Brain Barrier through Inhibiting RhoA Activation after Experimental Intracerebral Hemorrhage in Rats. Sci Rep. 2016 Mar 16; 6:23286.
    View in: PubMed
    Score: 0.109
  17. Zuo S, Ge H, Li Q, Zhang X, Hu R, Hu S, Liu X, Zhang JH, Chen Y, Feng H. Artesunate Protected Blood-Brain Barrier via Sphingosine 1 Phosphate Receptor 1/Phosphatidylinositol 3 Kinase Pathway After Subarachnoid Hemorrhage in Rats. Mol Neurobiol. 2017 03; 54(2):1213-1228.
    View in: PubMed
    Score: 0.108
  18. Manaenko A, Lekic T, Ma Q, Zhang JH, Tang J. Hydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice. Crit Care Med. 2013 May; 41(5):1266-75.
    View in: PubMed
    Score: 0.089
  19. Lekic T, Rolland W, Manaenko A, Krafft PR, Kamper JE, Suzuki H, Hartman RE, Tang J, Zhang JH. Evaluation of the hematoma consequences, neurobehavioral profiles, and histopathology in a rat model of pontine hemorrhage. J Neurosurg. 2013 Feb; 118(2):465-77.
    View in: PubMed
    Score: 0.087
  20. Zhan Y, Chen C, Suzuki H, Hu Q, Zhi X, Zhang JH. Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats. Crit Care Med. 2012 Apr; 40(4):1291-6.
    View in: PubMed
    Score: 0.083
  21. Fujii M, Duris K, Altay O, Soejima Y, Sherchan P, Zhang JH. Inhibition of Rho kinase by hydroxyfasudil attenuates brain edema after subarachnoid hemorrhage in rats. Neurochem Int. 2012 Feb; 60(3):327-33.
    View in: PubMed
    Score: 0.081
  22. Suzuki H, Ayer R, Sugawara T, Chen W, Sozen T, Hasegawa Y, Kanamaru K, Zhang JH. Role of osteopontin in early brain injury after subarachnoid hemorrhage in rats. Acta Neurochir Suppl. 2011; 110(Pt 1):75-9.
    View in: PubMed
    Score: 0.076
  23. Lekic T, Ostrowski RP, Suzuki H, Manaenko A, Rolland W, Fathali N, Tang J, Zhang JH. The postpartum period of pregnancy worsens brain injury and functional outcome after cerebellar hemorrhage in rats. Acta Neurochir Suppl. 2011; 111:37-41.
    View in: PubMed
    Score: 0.076
  24. Suzuki H, Ayer R, Sugawara T, Chen W, Sozen T, Hasegawa Y, Kanamaru K, Zhang JH. Protective effects of recombinant osteopontin on early brain injury after subarachnoid hemorrhage in rats. Crit Care Med. 2010 Feb; 38(2):612-8.
    View in: PubMed
    Score: 0.071
  25. Chen W, Hartman R, Ayer R, Marcantonio S, Kamper J, Tang J, Zhang JH. Matrix metalloproteinases inhibition provides neuroprotection against hypoxia-ischemia in the developing brain. J Neurochem. 2009 Nov; 111(3):726-36.
    View in: PubMed
    Score: 0.069
  26. Guo Z, Sun X, He Z, Jiang Y, Zhang X, Zhang JH. Matrix metalloproteinase-9 potentiates early brain injury after subarachnoid hemorrhage. Neurol Res. 2010 Sep; 32(7):715-20.
    View in: PubMed
    Score: 0.069
  27. Sugawara T, Jadhav V, Ayer R, Chen W, Suzuki H, Zhang JH. Thrombin inhibition by argatroban ameliorates early brain injury and improves neurological outcomes after experimental subarachnoid hemorrhage in rats. Stroke. 2009 Apr; 40(4):1530-2.
    View in: PubMed
    Score: 0.067
  28. Ayer RE, Sugawara T, Chen W, Tong W, Zhang JH. Melatonin decreases mortality following severe subarachnoid hemorrhage. J Pineal Res. 2008 Mar; 44(2):197-204.
    View in: PubMed
    Score: 0.062
  29. Tsubokawa T, Solaroglu I, Yatsushige H, Cahill J, Yata K, Zhang JH. Cathepsin and calpain inhibitor E64d attenuates matrix metalloproteinase-9 activity after focal cerebral ischemia in rats. Stroke. 2006 Jul; 37(7):1888-94.
    View in: PubMed
    Score: 0.055
  30. Cahill J, Calvert JW, Solaroglu I, Zhang JH. Vasospasm and p53-induced apoptosis in an experimental model of subarachnoid hemorrhage. Stroke. 2006 Jul; 37(7):1868-74.
    View in: PubMed
    Score: 0.055
  31. Ostrowski RP, Colohan AR, Zhang JH. Mechanisms of hyperbaric oxygen-induced neuroprotection in a rat model of subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2005 May; 25(5):554-71.
    View in: PubMed
    Score: 0.051
  32. Tang J, Liu J, Zhou C, Alexander JS, Nanda A, Granger DN, Zhang JH. Mmp-9 deficiency enhances collagenase-induced intracerebral hemorrhage and brain injury in mutant mice. J Cereb Blood Flow Metab. 2004 Oct; 24(10):1133-45.
    View in: PubMed
    Score: 0.049
  33. Kusaka G, Ishikawa M, Nanda A, Granger DN, Zhang JH. Signaling pathways for early brain injury after subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2004 Aug; 24(8):916-25.
    View in: PubMed
    Score: 0.049
  34. Zhou J, Guo P, Duan M, Li J, Ru X, Li L, Guo Z, Zhang JH, Feng H, Chen Y, Sun X. EphA4/EphrinB2 signaling mediates pericyte-induced transient glia limitans formation as a secondary protective barrier after subarachnoid hemorrhage in mice. Exp Neurol. 2023 02; 360:114293.
    View in: PubMed
    Score: 0.043
  35. Zhou Y, Yao Y, Sheng L, Zhang J, Zhang JH, Shao A. Osteopontin as a candidate of therapeutic application for the acute brain injury. J Cell Mol Med. 2020 08; 24(16):8918-8929.
    View in: PubMed
    Score: 0.037
  36. Xu S, Lu J, Shao A, Zhang JH, Zhang J. Glial Cells: Role of the Immune Response in Ischemic Stroke. Front Immunol. 2020; 11:294.
    View in: PubMed
    Score: 0.036
  37. Wang G, Guo Z, Tong L, Xue F, Krafft PR, Budbazar E, Zhang JH, Tang J. TLR7 (Toll-Like Receptor 7) Facilitates Heme Scavenging Through the BTK (Bruton Tyrosine Kinase)-CRT (Calreticulin)-LRP1 (Low-Density Lipoprotein Receptor-Related Protein-1)-Hx (Hemopexin) Pathway in Murine Intracerebral Hemorrhage. Stroke. 2018 12; 49(12):3020-3029.
    View in: PubMed
    Score: 0.033
  38. Iniaghe LO, Krafft PR, Klebe DW, Omogbai EKI, Zhang JH, Tang J. Dimethyl fumarate confers neuroprotection by casein kinase 2 phosphorylation of Nrf2 in murine intracerebral hemorrhage. Neurobiol Dis. 2015 Oct; 82:349-358.
    View in: PubMed
    Score: 0.026
  39. Hu Q, Chen C, Khatibi NH, Li L, Yang L, Wang K, Han J, Duan W, Zhang JH, Zhou C. Lentivirus-mediated transfer of MMP-9 shRNA provides neuroprotection following focal ischemic brain injury in rats. Brain Res. 2011 Jan 07; 1367:347-59.
    View in: PubMed
    Score: 0.019
  40. Hyong A, Jadhav V, Lee S, Tong W, Rowe J, Zhang JH, Tang J. Rosiglitazone, a PPAR gamma agonist, attenuates inflammation after surgical brain injury in rodents. Brain Res. 2008 Jun 18; 1215:218-24.
    View in: PubMed
    Score: 0.016
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

For technical support please contact support