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Judy Teale

TitleProfessor
InstitutionUniversity of Texas at San Antonio
DepartmentBiology
Address1 UTSA Cir
San Antonio TX 78249
Phone210) 458-7024
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    Collapse Overview 
    Collapse overview
    Dr. Teale’s research focus is Neurocysticercosis (NCC), a parasitic disease of the central nervous system caused by the helminth Taenia solium. The long term goal of this project has been to characterize the host immune response and the pathology associated with NCC. Apart from analyses of brain specimens from NCC patients, the lab has developed a mouse model of NCC by intra-cranial infection with the related cestode, Mesocestoides corti. Our studies have shown that the parasite releases glycans with distinct sugar specificities that are taken up by host cells in the CNS environment in both human and murine NCC. Immunological events following recognition of these glycan antigens likely play a critical role in the immunopathogenesis of NCC. Parasite glycan induced regulatory responses involving myeloid derived suppressor cells (MDSCs) are thought to be key in host protection; however, the receptors involved in this process are largely uncharacterized. C-type lectin receptors (CLRs) recognize glycan antigens of both pathogen and host origins and function in a wide variety of inflammatory and regulatory immune responses. Little is known regarding the expression of CLRs and their role in CNS infections which is the objective of this project. The lab hypothesizes that parasite released glycans induce differential expression of CLRs which modulate the expression of effector molecules as well as activation and trafficking of leukocytes. They further hypothesize that CLRs differentially modulate functions of MDSCs that likely influence the immunopathology in murine NCC.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Mishra PK, Li Q, Munoz LE, Mares CA, Morris EG, Teale JM, Cardona AE. Reduced Leukocyte Infiltration in Absence of Eosinophils Correlates with Decreased Tissue Damage and Disease Susceptibility in ?dblGATA Mice during Murine Neurocysticercosis. PLoS Negl Trop Dis. 2016 06; 10(6):e0004787. PMID: 27332553.
      Citations: 3     Fields:    Translation:AnimalsCells
    2. Mishra BB, Li Q, Steichen AL, Binstock BJ, Metzger DW, Teale JM, Sharma J. Galectin-3 functions as an alarmin: pathogenic role for sepsis development in murine respiratory tularemia. PLoS One. 2013; 8(3):e59616. PMID: 23527230.
      Citations: 15     Fields:    Translation:Animals
    3. Mishra PK, Teale JM. Changes in gene expression of pial vessels of the blood brain barrier during murine neurocysticercosis. PLoS Negl Trop Dis. 2013; 7(3):e2099. PMID: 23516647.
      Citations: 5     Fields:    Translation:Animals
    4. Mishra PK, Morris EG, Garcia JA, Cardona AE, Teale JM. Increased accumulation of regulatory granulocytic myeloid cells in mannose receptor C type 1-deficient mice correlates with protection in a mouse model of neurocysticercosis. Infect Immun. 2013 Apr; 81(4):1052-63. PMID: 23319563.
      Citations: 6     Fields:    Translation:AnimalsCells
    5. Mishra PK, Teale JM. Transcriptome analysis of the ependymal barrier during murine neurocysticercosis. J Neuroinflammation. 2012 Jun 25; 9:141. PMID: 22731103.
      Citations: 6     Fields:    Translation:Animals
    6. Khalifa RM, Teale JM, Mohamadain HS. Studies on some metacestodes immunohistochemical response in mice as a model for human cysticercosis: II-THI type immune response in experimental Braintaenia crassiceps infected mice. J Egypt Soc Parasitol. 2012 Apr; 42(1):183-90. PMID: 22662607.
      Citations: 2     Fields:    Translation:HumansAnimals
    7. Gundra UM, Mishra BB, Wong K, Teale JM. Increased disease severity of parasite-infected TLR2-/- mice is correlated with decreased central nervous system inflammation and reduced numbers of cells with alternatively activated macrophage phenotypes in a murine model of neurocysticercosis. Infect Immun. 2011 Jul; 79(7):2586-96. PMID: 21482681.
      Citations: 17     Fields:    Translation:AnimalsCells
    8. Sharma J, Mares CA, Li Q, Morris EG, Teale JM. Features of sepsis caused by pulmonary infection with Francisella tularensis Type A strain. Microb Pathog. 2011 Jul-Aug; 51(1-2):39-47. PMID: 21440052.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    9. Sharma J, Mishra BB, Li Q, Teale JM. TLR4-dependent activation of inflammatory cytokine response in macrophages by Francisella elongation factor Tu. Cell Immunol. 2011; 269(2):69-73. PMID: 21497800.
      Citations: 5     Fields:    Translation:AnimalsCells
    10. Mares CA, Sharma J, Ojeda SS, Li Q, Campos JA, Morris EG, Coalson JJ, Teale JM. Attenuated response of aged mice to respiratory Francisella novicida is characterized by reduced cell death and absence of subsequent hypercytokinemia. PLoS One. 2010 Nov 23; 5(11):e14088. PMID: 21124895.
      Citations: 14     Fields:    Translation:AnimalsCells
    11. Mishra BB, Gundra UM, Teale JM. STAT6?/? mice exhibit decreased cells with alternatively activated macrophage phenotypes and enhanced disease severity in murine neurocysticercosis. J Neuroimmunol. 2011 Mar; 232(1-2):26-34. PMID: 21051093.
      Citations: 19     Fields:    Translation:AnimalsCells
    12. Mares CA, Sharma J, Li Q, Rangel EL, Morris EG, Enriquez MI, Teale JM. Defect in efferocytosis leads to alternative activation of macrophages in Francisella infections. Immunol Cell Biol. 2011 Feb; 89(2):167-72. PMID: 20585334.
      Citations: 17     Fields:    Translation:AnimalsCells
    13. Alvarez JI, Mishra BB, Gundra UM, Mishra PK, Teale JM. Mesocestoides corti intracranial infection as a murine model for neurocysticercosis. Parasitology. 2010 Mar; 137(3):359-72. PMID: 20109250.
      Citations: 14     Fields:    Translation:HumansAnimals
    14. Abplanalp AL, Morris IR, Parida BK, Teale JM, Berton MT. TLR-dependent control of Francisella tularensis infection and host inflammatory responses. PLoS One. 2009 Nov 20; 4(11):e7920. PMID: 19936231.
      Citations: 38     Fields:    Translation:AnimalsCells
    15. Mares CA, Ojeda SS, Li Q, Morris EG, Coalson JJ, Teale JM. Aged mice display an altered pulmonary host response to Francisella tularensis live vaccine strain (LVS) infections. Exp Gerontol. 2010 Feb; 45(2):91-6. PMID: 19825409.
      Citations: 7     Fields:    Translation:AnimalsCells
    16. Mishra BB, Gundra UM, Wong K, Teale JM. MyD88-deficient mice exhibit decreased parasite-induced immune responses but reduced disease severity in a murine model of neurocysticercosis. Infect Immun. 2009 Dec; 77(12):5369-79. PMID: 19786565.
      Citations: 12     Fields:    Translation:AnimalsCells
    17. Sharma J, Li Q, Mishra BB, Georges MJ, Teale JM. Vaccination with an attenuated strain of Francisella novicida prevents T-cell depletion and protects mice infected with the wild-type strain from severe sepsis. Infect Immun. 2009 Oct; 77(10):4314-26. PMID: 19635830.
      Citations: 11     Fields:    Translation:AnimalsCells
    18. Alvarez JI, Krishnamurthy J, Teale JM. Doxycycline treatment decreases morbidity and mortality of murine neurocysticercosis: evidence for reduction of apoptosis and matrix metalloproteinase activity. Am J Pathol. 2009 Aug; 175(2):685-95. PMID: 19574432.
      Citations: 8     Fields:    Translation:Animals
    19. Sharma J, Li Q, Mishra BB, Pena C, Teale JM. Lethal pulmonary infection with Francisella novicida is associated with severe sepsis. J Leukoc Biol. 2009 Sep; 86(3):491-504. PMID: 19401387.
      Citations: 28     Fields:    Translation:AnimalsCells
    20. Sharma J, Li Q, Mishra BB, Teale JM. Lethal pulmonary infection with Francisella novicida causes depletion of alphabeta T cells from lungs. Cell Immunol. 2009; 257(1-2):1-4. PMID: 19356746.
      Citations: 3     Fields:    Translation:AnimalsCells
    21. Mishra BB, Gundra UM, Teale JM. Toll-like receptors in CNS parasitic infections. Curr Top Microbiol Immunol. 2009; 336:83-104. PMID: 19688329.
      Citations: 9     Fields:    Translation:HumansAnimals
    22. Mishra BB, Gundra UM, Teale JM. Expression and distribution of Toll-like receptors 11-13 in the brain during murine neurocysticercosis. J Neuroinflammation. 2008 Dec 12; 5:53. PMID: 19077284.
      Citations: 25     Fields:    Translation:AnimalsCells
    23. Ojeda SS, Wang ZJ, Mares CA, Chang TA, Li Q, Morris EG, Jerabek PA, Teale JM. Rapid dissemination of Francisella tularensis and the effect of route of infection. BMC Microbiol. 2008 Dec 09; 8:215. PMID: 19068128.
      Citations: 13     Fields:    Translation:AnimalsCells
    24. Mares CA, Ojeda SS, Morris EG, Li Q, Teale JM. Initial delay in the immune response to Francisella tularensis is followed by hypercytokinemia characteristic of severe sepsis and correlating with upregulation and release of damage-associated molecular patterns. Infect Immun. 2008 Jul; 76(7):3001-10. PMID: 18411294.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    25. Alvarez JI, Rivera J, Teale JM. Differential release and phagocytosis of tegument glycoconjugates in neurocysticercosis: implications for immune evasion strategies. PLoS Negl Trop Dis. 2008 Apr 09; 2(4):e218. PMID: 18398489.
      Citations: 19     Fields:    Translation:HumansAnimals
    26. Alvarez JI, Teale JM. Multiple expression of matrix metalloproteinases in murine neurocysticercosis: Implications for leukocyte migration through multiple central nervous system barriers. Brain Res. 2008 Jun 12; 1214:145-58. PMID: 18466882.
      Citations: 12     Fields:    Translation:AnimalsCells
    27. Teale JM. The relationship between pre-B cells and primary B cells. Immunol Today. 1982 Mar; 3(3):62-3. PMID: 25291247.
      Citations:    Fields:    
    28. Alvarez JI, Teale JM. Evidence for differential changes of junctional complex proteins in murine neurocysticercosis dependent upon CNS vasculature. Brain Res. 2007 Sep 12; 1169:98-111. PMID: 17686468.
      Citations: 19     Fields:    Translation:AnimalsCells
    29. Alvarez JI, Teale JM. Differential changes in junctional complex proteins suggest the ependymal lining as the main source of leukocyte infiltration into ventricles in murine neurocysticercosis. J Neuroimmunol. 2007 Jul; 187(1-2):102-13. PMID: 17597230.
      Citations: 14     Fields:    Translation:AnimalsCells
    30. Nash TE, Singh G, White AC, Rajshekhar V, Loeb JA, Proaño JV, Takayanagui OM, Gonzalez AE, Butman JA, DeGiorgio C, Del Brutto OH, Delgado-Escueta A, Evans CA, Gilman RH, Martinez SM, Medina MT, Pretell EJ, Teale J, Garcia HH. Treatment of neurocysticercosis: current status and future research needs. Neurology. 2006 Oct 10; 67(7):1120-7. PMID: 17030744.
      Citations: 54     Fields:    Translation:Humans
    31. Mishra BB, Mishra PK, Teale JM. Expression and distribution of Toll-like receptors in the brain during murine neurocysticercosis. J Neuroimmunol. 2006 Dec; 181(1-2):46-56. PMID: 17011049.
      Citations: 54     Fields:    Translation:Animals
    32. Alvarez JI, Teale JM. Breakdown of the blood brain barrier and blood-cerebrospinal fluid barrier is associated with differential leukocyte migration in distinct compartments of the CNS during the course of murine NCC. J Neuroimmunol. 2006 Apr; 173(1-2):45-55. PMID: 16406118.
      Citations: 30     Fields:    Translation:AnimalsCells
    33. Pammit MA, Budhavarapu VN, Raulie EK, Klose KE, Teale JM, Arulanandam BP. Intranasal interleukin-12 treatment promotes antimicrobial clearance and survival in pulmonary Francisella tularensis subsp. novicida infection. Antimicrob Agents Chemother. 2004 Dec; 48(12):4513-9. PMID: 15561819.
      Citations: 26     Fields:    Translation:AnimalsCells
    34. Obregón-Henao A, Londoño DP, Gómez DI, Trujillo J, Teale JM, Restrepo BI. In situ detection of antigenic glycoproteins in Taenia solium metacestodes. J Parasitol. 2003 Aug; 89(4):726-32. PMID: 14533682.
      Citations: 3     Fields:    Translation:Animals
    35. Cardona AE, Gonzalez PA, Teale JM. CC chemokines mediate leukocyte trafficking into the central nervous system during murine neurocysticercosis: role of gamma delta T cells in amplification of the host immune response. Infect Immun. 2003 May; 71(5):2634-42. PMID: 12704138.
      Citations: 26     Fields:    Translation:AnimalsCells
    36. Villota GE, Gomez DI, Volcy M, Franco AF, Cardona EA, Isaza R, Sanzón F, Teale JM, Restrepo BI. Similar diagnostic performance for neurocysticercosis of three glycoprotein preparations from Taenia solium metacestodes. Am J Trop Med Hyg. 2003 Mar; 68(3):276-80. PMID: 12685629.
      Citations: 2     Fields:    Translation:HumansAnimals
    37. Haslam SM, Restrepo BI, Obregón-Henao A, Teale JM, Morris HR, Dell A. Structural characterization of the N-linked glycans from Taenia solium metacestodes. Mol Biochem Parasitol. 2003 Jan; 126(1):103-7. PMID: 12554090.
      Citations: 8     Fields:    Translation:HumansAnimals
    38. Cardona AE, Teale JM. Gamma/delta T cell-deficient mice exhibit reduced disease severity and decreased inflammatory response in the brain in murine neurocysticercosis. J Immunol. 2002 Sep 15; 169(6):3163-71. PMID: 12218134.
      Citations: 20     Fields:    Translation:AnimalsCells
    39. Alvarez JI, Colegial CH, Castaño CA, Trujillo J, Teale JM, Restrepo BI. The human nervous tissue in proximity to granulomatous lesions induced by Taenia solium metacestodes displays an active response. J Neuroimmunol. 2002 Jun; 127(1-2):139-44. PMID: 12044985.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    40. Raaphorst FM, Schelonka RL, Rusnak J, Infante AJ, Teale JM. TCRBV CDR3 diversity of CD4+ and CD8+ T-lymphocytes in HIV-infected individuals. Hum Immunol. 2002 Jan; 63(1):51-60. PMID: 11916170.
      Citations: 4     Fields:    Translation:HumansCells
    41. Restrepo BI, Aguilar MI, Melby PC, Teale JM. Analysis of the peripheral immune response in patients with neurocysticercosis: evidence for T cell reactivity to parasite glycoprotein and vesicular fluid antigens. Am J Trop Med Hyg. 2001 Oct; 65(4):366-70. PMID: 11693886.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    42. Melby PC, Tabares A, Restrepo BI, Cardona AE, McGuff HS, Teale JM. Leishmania donovani: evolution and architecture of the splenic cellular immune response related to control of infection. Exp Parasitol. 2001 Sep; 99(1):17-25. PMID: 11708830.
      Citations: 18     Fields:    Translation:AnimalsCells
    43. Restrepo BI, Alvarez JI, Castaño JA, Arias LF, Restrepo M, Trujillo J, Colegial CH, Teale JM. Brain granulomas in neurocysticercosis patients are associated with a Th1 and Th2 profile. Infect Immun. 2001 Jul; 69(7):4554-60. PMID: 11401999.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    44. Kostense S, Raaphorst FM, Joling J, Notermans DW, Prins JM, Danner SA, Reiss P, Lange JM, Teale JM, Miedema F. T cell expansions in lymph nodes and peripheral blood in HIV-1-infected individuals: effect of antiretroviral therapy. AIDS. 2001 Jun 15; 15(9):1097-107. PMID: 11416711.
      Citations: 4     Fields:    Translation:HumansCells
    45. Obregón-Henao A, Gil DL, Gómez DI, Sanzón F, Teale JM, Restrepo BI. The role of N-linked carbohydrates in the antigenicity of Taenia solium metacestode glycoproteins of 12, 16 and 18 kD. Mol Biochem Parasitol. 2001 May; 114(2):209-15. PMID: 11378200.
      Citations: 9     Fields:    Translation:AnimalsCells
    46. Gokmen E, Bachier C, Raaphorst FM, Muller T, Armstrong D, LeMaistre CF, Teale JM. Ig heavy chain CDR3 size diversities are similar after conventional peripheral blood and ex vivo expanded hematopoietic cell transplants. Bone Marrow Transplant. 2001 Feb; 27(4):413-24. PMID: 11313671.
      Citations:    Fields:    Translation:HumansCells
    47. Gokmen E, Bachier C, Raaphorst FM, Muller T, Armstrong D, Lemaistre CF, Teale JM. Ex vivo-expanded hematopoietic cell graft recipients exhibit T cell repertoire diversity similar to that seen after conventional stem cell transplants. J Hematother Stem Cell Res. 2001 Feb; 10(1):53-66. PMID: 11276359.
      Citations:    Fields:    Translation:HumansCells
    48. Restrepo BI, Obregón-Henao A, Mesa M, Gil DL, Ortiz BL, Mejía JS, Villota GE, Sanzón F, Teale JM. Characterisation of the carbohydrate components of Taenia solium metacestode glycoprotein antigens. Int J Parasitol. 2000 May; 30(6):689-96. PMID: 10856502.
      Citations: 7     Fields:    Translation:AnimalsCells
    49. Bachier CR, Gokmen E, Teale J, Lanzkron S, Childs C, Franklin W, Shpall E, Douville J, Weber S, Muller T, Armstrong D, LeMaistre CF. Ex-vivo expansion of bone marrow progenitor cells for hematopoietic reconstitution following high-dose chemotherapy for breast cancer. Exp Hematol. 1999 Apr; 27(4):615-23. PMID: 10210319.
      Citations: 2     Fields:    Translation:HumansCellsCTClinical Trials
    50. Cardona AE, Restrepo BI, Jaramillo JM, Teale JM. Development of an animal model for neurocysticercosis: immune response in the central nervous system is characterized by a predominance of gamma delta T cells. J Immunol. 1999 Jan 15; 162(2):995-1002. PMID: 9916725.
      Citations: 32     Fields:    Translation:AnimalsCells
    51. Kostense S, Raaphorst FM, Notermans DW, Joling J, Hooibrink B, Pakker NG, Danner SA, Teale JM, Miedema F. Diversity of the T-cell receptor BV repertoire in HIV-1-infected patients reflects the biphasic CD4+ T-cell repopulation kinetics during highly active antiretroviral therapy. AIDS. 1998 Dec 24; 12(18):F235-40. PMID: 9875570.
      Citations: 5     Fields:    Translation:HumansCells
    52. Raaphorst FM, Gokmen E, Teale JM. Analysis of clonal diversity in mouse immunoglobulin heavy chain genes selected for size of the antigen combining site. Immunol Invest. 1998 Dec; 27(6):355-65. PMID: 9845421.
      Citations: 1     Fields:    Translation:AnimalsCells
    53. Gokmen E, Raaphorst FM, Boldt DH, Teale JM. Ig heavy chain third complementarity determining regions (H CDR3s) after stem cell transplantation do not resemble the developing human fetal H CDR3s in size distribution and Ig gene utilization. Blood. 1998 Oct 15; 92(8):2802-14. PMID: 9763565.
      Citations: 11     Fields:    Translation:HumansCells
    54. Restrepo BI, Llaguno P, Sandoval MA, Enciso JA, Teale JM. Analysis of immune lesions in neurocysticercosis patients: central nervous system response to helminth appears Th1-like instead of Th2. J Neuroimmunol. 1998 Aug 14; 89(1-2):64-72. PMID: 9726827.
      Citations: 18     Fields:    Translation:HumansCells
    55. Schelonka RL, Raaphorst FM, Infante D, Kraig E, Teale JM, Infante AJ. T cell receptor repertoire diversity and clonal expansion in human neonates. Pediatr Res. 1998 Mar; 43(3):396-402. PMID: 9505280.
      Citations: 15     Fields:    Translation:HumansCells
    56. Pan PY, Lieber MR, Teale JM. The role of recombination signal sequences in the preferential joining by deletion in DH-JH recombination and in the ordered rearrangement of the IgH locus. Int Immunol. 1997 Apr; 9(4):515-22. PMID: 9138011.
      Citations: 4     Fields:    Translation:AnimalsCells
    57. Raaphorst FM, Raman CS, Nall BT, Teale JM. Molecular mechanisms governing reading frame choice of immunoglobulin diversity genes. Immunol Today. 1997 Jan; 18(1):37-43. PMID: 9018973.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    58. Brey RL, Cote S, Barohn R, Jackson C, Crawley R, Teale JM. Model for the neuromuscular complications of systemic lupus erythematosus. Lupus. 1995 Jun; 4(3):209-12. PMID: 7655491.
      Citations: 2     Fields:    Translation:AnimalsCells
    59. Turaga PS, Berton MT, Teale JM. Frequency of B cells expressing germ-line gamma 1 transcripts upon IL-4 induction. J Immunol. 1993 Aug 01; 151(3):1383-90. PMID: 8335934.
      Citations:    Fields:    Translation:AnimalsCells
    60. Ernani FP, Teale JM. Release of stress proteins from Mesocestoides corti is a brefeldin A-inhibitable process: evidence for active export of stress proteins. Infect Immun. 1993 Jun; 61(6):2596-601. PMID: 8500897.
      Citations: 5     Fields:    Translation:Animals
    61. Medina CA, Teale JM. Restricted kappa chain expression in early ontogeny: biased utilization of V kappa exons and preferential V kappa-J kappa recombinations. J Exp Med. 1993 May 01; 177(5):1317-30. PMID: 8478611.
      Citations: 4     Fields:    Translation:AnimalsCells
    62. Estes DM, Turaga PS, Sievers KM, Teale JM. Characterization of an unusual cell type (CD4+ CD3-) expanded by helminth infection and related to the parasite stress response. J Immunol. 1993 Mar 01; 150(5):1846-56. PMID: 8436820.
      Citations: 3     Fields:    Translation:AnimalsCells
    63. Teale JM, Sievers KM, Crawley RR, Kotzin BL. Ig V kappa family repertoire of plasma cells derived from autoimmune MRL mice. J Immunol. 1992 Jan 01; 148(1):142-8. PMID: 1727864.
      Citations: 3     Fields:    Translation:AnimalsCells
    64. Teale JM, Medina CA. Comparative expression of adult and fetal V gene repertoires. Int Rev Immunol. 1992; 8(2-3):95-111. PMID: 1602218.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    65. Yeh TM, Korsmeyer SJ, Teale JM. Skewed B cell VH family repertoire in Bcl-2-Ig transgenic mice. Int Immunol. 1991 Dec; 3(12):1329-33. PMID: 1777425.
      Citations: 1     Fields:    Translation:AnimalsCells
    66. Estes DM, Teale JM. Biochemical and functional analysis of extracellular stress proteins of Mesocestoides corti. J Immunol. 1991 Dec 01; 147(11):3926-34. PMID: 1940374.
      Citations: 6     Fields:    Translation:AnimalsCells
    67. Bangs LA, Sanz IE, Teale JM. Comparison of D, JH, and junctional diversity in the fetal, adult, and aged B cell repertoires. J Immunol. 1991 Mar 15; 146(6):1996-2004. PMID: 1672338.
      Citations: 35     Fields:    Translation:AnimalsCells
    68. Estes DM, Teale JM. In vivo effects of anticytokine antibodies on isotype restriction in Mesocestoides corti-infected BALB/c mice. Infect Immun. 1991 Mar; 59(3):836-42. PMID: 1997434.
      Citations: 5     Fields:    Translation:AnimalsPHPublic Health
    69. Jeong HD, Teale JM. Contribution of the CD5+ B cell to D-proximal VH family expression early in ontogeny. J Immunol. 1990 Oct 15; 145(8):2725-9. PMID: 1698861.
      Citations: 4     Fields:    Translation:AnimalsCells
    70. Desai BB, Abraham KM, Teale JM. The isotype potential of B cells present in BALB/c mice chronically infected with Mesocestoides corti. Cell Immunol. 1990 Oct 01; 130(1):139-49. PMID: 1975771.
      Citations: 1     Fields:    Translation:AnimalsCells
    71. Jones SL, Teale JM, Riley SC, Klinman NR, Tucker PW. Molecular analysis of neonatal IgA expression: implications for class switching, allelic polymorphism and somatic mutation. Immunol Res. 1990; 9(2):147-56. PMID: 1971834.
      Citations: 1     Fields:    Translation:AnimalsCells
    72. Teale JM, Morris EG. Comparison of V kappa gene family expression in adult and fetal B cells. J Immunol. 1989 Oct 15; 143(8):2768-72. PMID: 2507639.
      Citations: 9     Fields:    Translation:AnimalsCells
    73. Jeong HD, Teale JM. VH gene family repertoire of resting B cells. Preferential use of D-proximal families early in development may be due to distinct B cell subsets. J Immunol. 1989 Oct 15; 143(8):2752-60. PMID: 2507637.
      Citations: 11     Fields:    Translation:AnimalsCells
    74. Komisar JL, Leung KY, Crawley RR, Talal N, Teale JM. Ig VH gene family repertoire of plasma cells derived from lupus-prone MRL/lpr and MRL/++ mice. J Immunol. 1989 Jul 01; 143(1):340-7. PMID: 2499632.
      Citations: 3     Fields:    Translation:AnimalsCells
    75. Desai BB, Sosolik RC, Ciaravino V, Teale JM. Effect of fetal exposure to ultrasound on the development of functional, antigen-specific B lymphocytes in fetal and neonatal BALB/c mice. Ultrasound Med Biol. 1989; 15(6):575-80. PMID: 2477928.
      Citations:    Fields:    Translation:AnimalsCells
    76. Desai BB, Sosolik RC, Ciaravino V, Teale JM. Effect of fetal exposure to ultrasound on B cell development in BALB/c mice. Ultrasound Med Biol. 1989; 15(6):567-73. PMID: 2678661.
      Citations:    Fields:    Translation:AnimalsCells
    77. Sosolik RC, Desai BB, Ciaravino V, Teale JM. Effect of fetal exposure to ultrasound on B lymphocyte function and antibody class production. Ultrasound Med Biol. 1989; 15(6):581-7. PMID: 2477929.
      Citations:    Fields:    Translation:AnimalsCells
    78. Teale JM, Landreth KS. Effect of growth and differentiation stimuli on the development of antigen-responsive B cells in fetal liver. Cell Immunol. 1988 Dec; 117(2):389-98. PMID: 3264215.
      Citations:    Fields:    Translation:AnimalsCells
    79. Jeong HD, Teale JM. Comparison of the fetal and adult functional B cell repertoires by analysis of VH gene family expression. J Exp Med. 1988 Aug 01; 168(2):589-603. PMID: 3261774.
      Citations: 30     Fields:    Translation:AnimalsCells
    80. Jeong HD, Komisar JL, Kraig E, Teale JM. Strain-dependent expression of VH gene families. J Immunol. 1988 Apr 01; 140(7):2436-41. PMID: 3127467.
      Citations: 12     Fields:    Translation:AnimalsCells
    81. Abraham KM, Teale JM. The contribution of parasite-specific T cells to isotype restriction in Mesocestoides corti-infected mice. J Immunol. 1987 Oct 15; 139(8):2530-7. PMID: 2958553.
      Citations: 3     Fields:    Translation:AnimalsCells
    82. Abraham KM, Teale JM. Isotype restriction during infection of mice with the cestode Mesocestoides corti: role of immune suppression. J Immunol. 1987 Mar 15; 138(6):1699-704. PMID: 2950169.
      Citations: 8     Fields:    Translation:AnimalsCells
    83. Teale JM, Abraham KM. The regulation of antibody class expression. Immunol Today. 1987; 8(4):122-6. PMID: 25289816.
      Citations: 1     Fields:    
    84. Teale JM, Janeway CA. Influence of immunoglobulin-dependent T cells on antibody class switching. J Immunol. 1986 Aug 01; 137(3):749-54. PMID: 3487585.
      Citations: 3     Fields:    Translation:AnimalsCells
    85. Lafrenz D, Teale JM, Klinman NR, Strober S. Surface IgG-bearing cells retain the capacity to secrete IgM. J Immunol. 1986 Mar 15; 136(6):2076-9. PMID: 3485140.
      Citations: 5     Fields:    Translation:AnimalsCells
    86. Teale JM, Kearney JF. Clonotypic analysis of the fetal B cell repertoire: evidence for an early and predominant expression of idiotypes associated with the VH 36-60 family. J Mol Cell Immunol. 1986; 2(5):283-92. PMID: 2908178.
      Citations: 2     Fields:    Translation:AnimalsCells
    87. Teale JM. B cell immune repertoire diversifies in a predictable temporal order in vitro. J Immunol. 1985 Aug; 135(2):954-8. PMID: 3874238.
      Citations: 6     Fields:    Translation:AnimalsCells
    88. Klinman NR, Riley RL, Morrow PR, Jemmerson RR, Teale JM. Tolerance and B cell repertoire establishment. Fed Proc. 1985 May; 44(8):2488-92. PMID: 2580742.
      Citations: 1     Fields:    Translation:AnimalsCells
    89. Teale JM, Klinman NR. Membrane and metabolic requirements for tolerance induction of neonatal B cells. J Immunol. 1984 Oct; 133(4):1811-7. PMID: 6332134.
      Citations: 3     Fields:    Translation:AnimalsCells
    90. Searle CE, Teale J. Carcinogenic risks of fishermen's dyes. Lancet. 1984 Mar 10; 1(8376):563. PMID: 6142274.
      Citations:    Fields:    Translation:HumansAnimals
    91. Teale JM. The use of specific helper T cell clones to study the regulation of isotype expression by antigen-stimulated B cell clones. J Immunol. 1983 Nov; 131(5):2170-7. PMID: 6195254.
      Citations: 3     Fields:    Translation:AnimalsCells
    92. Teale JM. Abnormalities in isotype expression in CBA/N mice due to stimulatory environment rather than a B cell defect. J Immunol. 1983 Jan; 130(1):72-7. PMID: 6600199.
      Citations: 7     Fields:    Translation:AnimalsCells
    93. Teale JM. The potential of B lymphocytes for isotype expression. Fed Proc. 1982 Jul; 41(9):2497-501. PMID: 6979483.
      Citations: 5     Fields:    Translation:AnimalsCells
    94. Searle CE, Teale J. Chrysoidine-dyed bait: a possible carcinogenic hazard to anglers? Lancet. 1982 Mar 06; 1(8271):564. PMID: 6120417.
      Citations: 2     Fields:    Translation:HumansAnimals
    95. Lafrenz D, Teale JM, Strober S. Role of IgD in immunological memory. Ann N Y Acad Sci. 1982; 399:375-88. PMID: 6984620.
      Citations: 1     Fields:    Translation:AnimalsCells
    96. Klinman NR, Wylie DE, Teale JM. B-cell development. Immunol Today. 1981 Nov; 2(11):212-6. PMID: 25290455.
      Citations:    Fields:    
    97. Teale JM, Lafrenz D, Klinman NR, Strober S. Immunoglobulin class commitment exhibited by B lymphocytes separated according to surface isotype. J Immunol. 1981 May; 126(5):1952-7. PMID: 6971315.
      Citations: 13     Fields:    Translation:AnimalsCells
    98. Teale JM, Liu FT, Katz DH. A clonal analysis of the IgE response and its implications with regard to isotope commitment. J Exp Med. 1981 Apr 01; 153(4):783-92. PMID: 6972990.
      Citations: 12     Fields:    Translation:AnimalsCells
    99. Teale JM, Klinman NR. Tolerance as an active process. Nature. 1980 Nov 27; 288(5789):385-7. PMID: 6159554.
      Citations: 13     Fields:    Translation:AnimalsCells
    100. Teale JM, Pike BL, Craig J, Nossal GJ, McKenzie IF. Clonal analysis of B-lymphocyte subpopulations separated on the basis of Lyb surface antigens. Cell Immunol. 1980 Oct; 55(2):272-82. PMID: 6159108.
      Citations: 1     Fields:    Translation:AnimalsCells
    101. Teale JM, Mandel TE. Ontogenic development of B-lymphocyte function and tolerance susceptibility in vivo and in an in vitro organ culture system. J Exp Med. 1980 Feb 01; 151(2):429-45. PMID: 6965399.
      Citations: 9     Fields:    Translation:AnimalsCells
    102. Howard M, Baker J, Teale J, Shortman K. Antigen-initiated B-lymphocyte differentiation. XVII. The inhibitory effects of recent antigen prepriming on the subsequent responsiveness of 'pre-progenitor' B cells. Scand J Immunol. 1980; 11(3):327-34. PMID: 9537061.
      Citations:    Fields:    Translation:AnimalsCells
    103. Teale JM, Mackay IR. Autoimmune disease and the theory of clonal abortion. Is it still relevant? Lancet. 1979 Aug 11; 2(8137):284-7. PMID: 88613.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    104. Layton JE, Teale JM, Nossal GJ. Cloning of B cells positive or negative for surface IgD. II. Triggering and tolerance in the T-dependent splenic focus assay. J Immunol. 1979 Aug; 123(2):709-13. PMID: 379216.
      Citations: 9     Fields:    Translation:AnimalsCells
    105. Teale JM, Layton JE, Nossal GJ. In vitro model for natural tolerance to self-antigens. Inhibition of the development of surface-immunoglobulin-negative lymphocytes into T-dependent responsive B cells by antigen. J Exp Med. 1979 Aug 01; 150(2):205-17. PMID: 88498.
      Citations: 7     Fields:    Translation:AnimalsCells
    106. Shortman K, Howard M, Teale J, Baker J. Antigen-initiated B lymphocyte differentiation. XVI. Primary and secondary adoptive responses involve two sequential stages, antigen nonspecific then antigen specific, in the generation of specific AFC. J Immunol. 1979 Jun; 122(6):2465-72. PMID: 87463.
      Citations: 4     Fields:    Translation:AnimalsCells
    107. Nossal GJ, Pike BL, Teale JM, Layton JE, Kay TW, Battye FL. Cell fractionation methods and the target cells for clonal abortion of B lymphocytes. Immunol Rev. 1979; 43:184-216. PMID: 365710.
      Citations: 2     Fields:    Translation:AnimalsCells
    108. Teale JM, Howard MC, Falzon E, Nossal GJ. B lymphocyte subpopulations separated by velocity sedimentation. I. Characterization of immune function in an in vitro splenic focus assay. J Immunol. 1978 Dec; 121(6):2554-60. PMID: 152795.
      Citations: 5     Fields:    Translation:AnimalsCells
    109. Teale JM, Howard MC, Nossal GJ. B lymphocyte subpopulations separated by velocity sedimentation. II. Characterization of tolerance susceptibility. J Immunol. 1978 Dec; 121(6):2561-5. PMID: 363949.
      Citations: 4     Fields:    Translation:AnimalsCells
    110. Benjamin DC, Teale JM. The antigenic structure of bovine serum albumin. Evidence for multiple, different, domain-specific antigenic determinants. J Biol Chem. 1978 Nov 25; 253(22):8087-92. PMID: 81834.
      Citations: 5     Fields:    
    111. Benjamin DC, Teale JM. Tolerance to azobenzenearsonate: preferential loss of the major normal cross-reactive idiotype. J Immunol. 1978 Jan; 120(1):202-8. PMID: 75223.
      Citations: 1     Fields:    Translation:Animals
    112. Teale JM, Benjamin DC. Antibody as immunological probe for studying refolding of bovine serum albumin. Refolding within each domain. J Biol Chem. 1977 Jul 10; 252(13):4521-6. PMID: 873903.
      Citations: 5     Fields:    Translation:Cells
    113. Teale JM, Benjamin DC. Antibody as an immunological probe for studying the refolding of bovine serum albumin. I. The catalysis of reoxidation of reduced bovine serum albumin by glutathione and a disulfide interchange enzyme. J Biol Chem. 1976 Aug 10; 251(15):4603-8. PMID: 947897.
      Citations: 5     Fields:    Translation:Cells
    114. Teale JM, Benjamin DC. Antibody as an immunological probe for studying the refolding of bovine serum albumin. II. Evidence for the independent refolding of the domains of the molecule. J Biol Chem. 1976 Aug 10; 251(15):4609-15. PMID: 947898.
      Citations: 5     Fields:    Translation:Cells
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