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John R. McCarrey

TitleProfessor and Kleberg Distinguished Chair in Cellular and Molecular Biolog
Faculty RankProfessor
InstitutionUniversity of Texas at San Antonio
DepartmentDepartment of biology
AddressOne UTSA Circle
San Antonio TX 78249
Phone(210) 458-4507
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    Collapse Overview 
    Collapse overview
    Research in Dr. McCarrey’s lab is centered on mammalian germ cells and stem cells. Experimental models include the mouse, the baboon, and the opossum. The lab is interested in the epigenetic regulation of cell functions, including determination of cell fates, maintenance of genetic integrity, regulation of gene expression, genomic imprinting, X-chromosome inactivation and meiotic sex chromosome inactivation, methods of assisted reproduction, the evolution of tissue-specific gene expression in mammalian species, and developing the baboon as a model system for testing stem cell-based therapeutic applications.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mori Y, Ogonuki N, Hasegawa A, Kanatsu-Shinohara M, Ogura A, Wang Y, McCarrey JR, Shinohara T. OGG1 protects mouse spermatogonial stem cells from reactive oxygen species in culture†. Biol Reprod. 2020 Nov 30. PMID: 33252132.
      Citations:    Fields:    
    2. Cheng K, Chen IC, Cheng CE, Mutoji K, Hale BJ, Hermann BP, Geyer CB, Oatley JM, McCarrey JR. Unique Epigenetic Programming Distinguishes Regenerative Spermatogonial Stem Cells in the Developing Mouse Testis. iScience. 2020 Oct 23; 23(10):101596. PMID: 33083754.
      Citations:    
    3. Ben Maamar M, Beck D, Nilsson E, McCarrey JR, Skinner MK. Developmental origins of transgenerational sperm histone retention following ancestral exposures. Dev Biol. 2020 Sep 01; 465(1):31-45. PMID: 32628935.
      Citations:    Fields:    
    4. Robaire B, Eddy M, Goldberg E, Griswold M, Heckert L, McCarrey J, Orgebin-Crist MC, Papadopoulos V, Trasler J, Wright W, Yan W, Zirkin B. Celebrating the Silver Anniversary of the North American Testis Workshop. Andrology. 2020 07; 8(4):820-824. PMID: 31968155.
      Citations:    Fields:    
    5. Skinner MK, Nilsson E, Sadler-Riggleman I, Beck D, Ben Maamar M, McCarrey JR. Transgenerational sperm DNA methylation epimutation developmental origins following ancestral vinclozolin exposure. Epigenetics. 2019 07; 14(7):721-739. PMID: 31079544.
      Citations: 5     Fields:    Translation:AnimalsCells
    6. Ben Maamar M, Nilsson E, Sadler-Riggleman I, Beck D, McCarrey JR, Skinner MK. Developmental origins of transgenerational sperm DNA methylation epimutations following ancestral DDT exposure. Dev Biol. 2019 01 15; 445(2):280-293. PMID: 30500333.
      Citations: 8     Fields:    Translation:AnimalsCells
    7. Hermann BP, Cheng K, Singh A, Roa-De La Cruz L, Mutoji KN, Chen IC, Gildersleeve H, Lehle JD, Mayo M, Westernströer B, Law NC, Oatley MJ, Velte EK, Niedenberger BA, Fritze D, Silber S, Geyer CB, Oatley JM, McCarrey JR. The Mammalian Spermatogenesis Single-Cell Transcriptome, from Spermatogonial Stem Cells to Spermatids. Cell Rep. 2018 11 06; 25(6):1650-1667.e8. PMID: 30404016.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    8. Navara CS, Chaudhari S, McCarrey JR. Optimization of culture conditions for the derivation and propagation of baboon (Papio anubis) induced pluripotent stem cells. PLoS One. 2018; 13(3):e0193195. PMID: 29494646.
      Citations: 4     Fields:    Translation:AnimalsCells
    9. Wichman L, Somasundaram S, Breindel C, Valerio DM, McCarrey JR, Hodges CA, Khalil AM. Dynamic expression of long noncoding RNAs reveals their potential roles in spermatogenesis and fertility. Biol Reprod. 2017 Aug 01; 97(2):313-323. PMID: 29044429.
      Citations: 16     Fields:    Translation:AnimalsCells
    10. Cooper DJ, Chen IC, Hernandez C, Wang Y, Walter CA, McCarrey JR. Pluripotent cells display enhanced resistance to mutagenesis. Stem Cell Res. 2017 03; 19:113-117. PMID: 28129601.
      Citations: 3     Fields:    Translation:AnimalsCells
    11. McCarrey JR, Lehle JD, Raju SS, Wang Y, Nilsson EE, Skinner MK. Tertiary Epimutations - A Novel Aspect of Epigenetic Transgenerational Inheritance Promoting Genome Instability. PLoS One. 2016; 11(12):e0168038. PMID: 27992467.
      Citations: 8     Fields:    Translation:AnimalsCells
    12. Chen IC, Hernandez C, Xu X, Cooney A, Wang Y, McCarrey JR. Dynamic Variations in Genetic Integrity Accompany Changes in Cell Fate. Stem Cells Dev. 2016 11 15; 25(22):1698-1708. PMID: 27627671.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    13. Mutoji K, Singh A, Nguyen T, Gildersleeve H, Kaucher AV, Oatley MJ, Oatley JM, Velte EK, Geyer CB, Cheng K, McCarrey JR, Hermann BP. TSPAN8 Expression Distinguishes Spermatogonial Stem Cells in the Prepubertal Mouse Testis. Biol Reprod. 2016 12; 95(6):117. PMID: 27733379.
      Citations: 12     Fields:    Translation:AnimalsCells
    14. Lesch BJ, Silber SJ, McCarrey JR, Page DC. Corrigendum: Parallel evolution of male germline epigenetic poising and somatic development in animals. Nat Genet. 2016 09 28; 48(10):1296. PMID: 27681290.
      Citations: 2     Fields:    
    15. Grow DA, McCarrey JR, Navara CS. Advantages of nonhuman primates as preclinical models for evaluating stem cell-based therapies for Parkinson's disease. Stem Cell Res. 2016 09; 17(2):352-366. PMID: 27622596.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    16. Grow DA, Simmons DV, Gomez JA, Wanat MJ, McCarrey JR, Paladini CA, Navara CS. Differentiation and Characterization of Dopaminergic Neurons From Baboon Induced Pluripotent Stem Cells. Stem Cells Transl Med. 2016 09; 5(9):1133-44. PMID: 27343168.
      Citations: 5     Fields:    Translation:AnimalsCells
    17. Lesch BJ, Silber SJ, McCarrey JR, Page DC. Parallel evolution of male germline epigenetic poising and somatic development in animals. Nat Genet. 2016 08; 48(8):888-94. PMID: 27294618.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    18. Shum EY, Jones SH, Shao A, Dumdie J, Krause MD, Chan WK, Lou CH, Espinoza JL, Song HW, Phan MH, Ramaiah M, Huang L, McCarrey JR, Peterson KJ, De Rooij DG, Cook-Andersen H, Wilkinson MF. The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay. Cell. 2016 Apr 07; 165(2):382-95. PMID: 27040500.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    19. McCarrey JR. EPIGENETICS. The epigenome--a family affair. Science. 2015 Nov 06; 350(6261):634-5. PMID: 26542557.
      Citations: 4     Fields:    Translation:AnimalsCells
    20. Sosa E, Flores L, Yan W, McCarrey JR. Escape of X-linked miRNA genes from meiotic sex chromosome inactivation. Development. 2015 Nov 01; 142(21):3791-800. PMID: 26395485.
      Citations: 6     Fields:    Translation:AnimalsCells
    21. Hermann BP, Mutoji KN, Velte EK, Ko D, Oatley JM, Geyer CB, McCarrey JR. Transcriptional and translational heterogeneity among neonatal mouse spermatogonia. Biol Reprod. 2015 Feb; 92(2):54. PMID: 25568304.
      Citations: 26     Fields:    Translation:AnimalsCells
    22. Ortogero N, Schuster AS, Oliver DK, Riordan CR, Hong AS, Hennig GW, Luong D, Bao J, Bhetwal BP, Ro S, McCarrey JR, Yan W. A novel class of somatic small RNAs similar to germ cell pachytene PIWI-interacting small RNAs. J Biol Chem. 2014 Nov 21; 289(47):32824-34. PMID: 25320077.
      Citations: 9     Fields:    Translation:AnimalsCells
    23. Cooper DJ, Walter CA, McCarrey JR. Co-regulation of pluripotency and genetic integrity at the genomic level. Stem Cell Res. 2014 Nov; 13(3 Pt A):508-19. PMID: 25451711.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    24. McCarrey JR. Distinctions between transgenerational and non-transgenerational epimutations. Mol Cell Endocrinol. 2014 Dec; 398(1-2):13-23. PMID: 25079508.
      Citations: 10     Fields:    Translation:HumansCellsPHPublic Health
    25. Navara CS, Hornecker J, Grow D, Chaudhari S, Hornsby PJ, Ichida JK, Eggan K, McCarrey JR. Derivation of induced pluripotent stem cells from the baboon: a nonhuman primate model for preclinical testing of stem cell therapies. Cell Reprogram. 2013 Dec; 15(6):495-502. PMID: 24182315.
      Citations: 8     Fields:    Translation:AnimalsCells
    26. Yang Z, Yoshioka H, McCarrey JR. Sequence-specific promoter elements regulate temporal-specific changes in chromatin required for testis-specific activation of the Pgk2 gene. Reproduction. 2013; 146(5):501-16. PMID: 24000349.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    27. Lesch BJ, Dokshin GA, Young RA, McCarrey JR, Page DC. A set of genes critical to development is epigenetically poised in mouse germ cells from fetal stages through completion of meiosis. Proc Natl Acad Sci U S A. 2013 Oct 01; 110(40):16061-6. PMID: 24043772.
      Citations: 47     Fields:    Translation:AnimalsCells
    28. McCarrey JR. Toward a more precise and informative nomenclature describing fetal and neonatal male germ cells in rodents. Biol Reprod. 2013 Aug; 89(2):47. PMID: 23843236.
      Citations: 16     Fields:    Translation:AnimalsCells
    29. Skinner MK, Guerrero-Bosagna C, Haque M, Nilsson E, Bhandari R, McCarrey JR. Environmentally induced transgenerational epigenetic reprogramming of primordial germ cells and the subsequent germ line. PLoS One. 2013; 8(7):e66318. PMID: 23869203.
      Citations: 70     Fields:    Translation:AnimalsCells
    30. Zhou J, McCarrey JR, Wang PJ. A 1.1-Mb segmental deletion on the X chromosome causes meiotic failure in male mice. Biol Reprod. 2013 Jun; 88(6):159. PMID: 23677977.
      Citations: 5     Fields:    Translation:AnimalsCells
    31. Arango NA, Li L, Dabir D, Nicolau F, Pieretti-Vanmarcke R, Koehler C, McCarrey JR, Lu N, Donahoe PK. Meiosis I arrest abnormalities lead to severe oligozoospermia in meiosis 1 arresting protein (M1ap)-deficient mice. Biol Reprod. 2013 Mar; 88(3):76. PMID: 23269666.
      Citations: 2     Fields:    Translation:AnimalsCells
    32. Murphey P, McLean DJ, McMahan CA, Walter CA, McCarrey JR. Enhanced genetic integrity in mouse germ cells. Biol Reprod. 2013 Jan; 88(1):6. PMID: 23153565.
      Citations: 10     Fields:    Translation:AnimalsCells
    33. Ortogero N, Hennig GW, Langille C, Ro S, McCarrey JR, Yan W. Computer-assisted annotation of murine Sertoli cell small RNA transcriptome. Biol Reprod. 2013 Jan; 88(1):3. PMID: 23136297.
      Citations: 10     Fields:    Translation:AnimalsCells
    34. de Waal E, Yamazaki Y, Ingale P, Bartolomei MS, Yanagimachi R, McCarrey JR. Gonadotropin stimulation contributes to an increased incidence of epimutations in ICSI-derived mice. Hum Mol Genet. 2012 Oct 15; 21(20):4460-72. PMID: 22802074.
      Citations: 16     Fields:    Translation:Animals
    35. Grant J, Mahadevaiah SK, Khil P, Sangrithi MN, Royo H, Duckworth J, McCarrey JR, VandeBerg JL, Renfree MB, Taylor W, Elgar G, Camerini-Otero RD, Gilchrist MJ, Turner JM. Rsx is a metatherian RNA with Xist-like properties in X-chromosome inactivation. Nature. 2012 Jul 12; 487(7406):254-8. PMID: 22722828.
      Citations: 46     Fields:    Translation:AnimalsCells
    36. Song HW, Dann CT, McCarrey JR, Meistrich ML, Cornwall GA, Wilkinson MF. Dynamic expression pattern and subcellular localization of the Rhox10 homeobox transcription factor during early germ cell development. Reproduction. 2012 May; 143(5):611-24. PMID: 22393026.
      Citations: 11     Fields:    Translation:AnimalsCells
    37. de Waal E, Yamazaki Y, Ingale P, Bartolomei M, Yanagimachi R, McCarrey JR. Primary epimutations introduced during intracytoplasmic sperm injection (ICSI) are corrected by germline-specific epigenetic reprogramming. Proc Natl Acad Sci U S A. 2012 Mar 13; 109(11):4163-8. PMID: 22371603.
      Citations: 25     Fields:    Translation:AnimalsCells
    38. McCarrey JR. The epigenome as a target for heritable environmental disruptions of cellular function. Mol Cell Endocrinol. 2012 May 06; 354(1-2):9-15. PMID: 21970811.
      Citations: 15     Fields:    Translation:HumansAnimalsPHPublic Health
    39. Thomas K, Sung DY, Chen X, Thompson W, Chen YE, McCarrey J, Walker W, Griswold M. Developmental patterns of PPAR and RXR gene expression during spermatogenesis. Front Biosci (Elite Ed). 2011 Jun 01; 3:1209-20. PMID: 21622127.
      Citations: 7     Fields:    Translation:AnimalsCells
    40. Roy Choudhury D, Small C, Wang Y, Mueller PR, Rebel VI, Griswold MD, McCarrey JR. Microarray-based analysis of cell-cycle gene expression during spermatogenesis in the mouse. Biol Reprod. 2010 Oct; 83(4):663-75. PMID: 20631398.
      Citations: 6     Fields:    Translation:AnimalsCells
    41. McCarrey JR, Eddy EM. Introductory overview to the proceedings of the XXth North American Testis Workshop. J Androl. 2010 Jan-Feb; 31(1):1-4. PMID: 19875486.
      Citations:    Fields:    Translation:HumansAnimalsCells
    42. Yan W, McCarrey JR. Sex chromosome inactivation in the male. Epigenetics. 2009 Oct 01; 4(7):452-6. PMID: 19838052.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    43. Danshina PV, Geyer CB, Dai Q, Goulding EH, Willis WD, Kitto GB, McCarrey JR, Eddy EM, O'Brien DA. Phosphoglycerate kinase 2 (PGK2) is essential for sperm function and male fertility in mice. Biol Reprod. 2010 Jan; 82(1):136-45. PMID: 19759366.
      Citations: 69     Fields:    Translation:AnimalsCells
    44. Mahadevaiah SK, Royo H, VandeBerg JL, McCarrey JR, Mackay S, Turner JM. Key features of the X inactivation process are conserved between marsupials and eutherians. Curr Biol. 2009 Sep 15; 19(17):1478-84. PMID: 19716301.
      Citations: 35     Fields:    Translation:AnimalsCells
    45. Song R, Ro S, Michaels JD, Park C, McCarrey JR, Yan W. Many X-linked microRNAs escape meiotic sex chromosome inactivation. Nat Genet. 2009 Apr; 41(4):488-93. PMID: 19305411.
      Citations: 89     Fields:    Translation:HumansAnimalsCells
    46. Murphey P, Yamazaki Y, McMahan CA, Walter CA, Yanagimachi R, McCarrey JR. Epigenetic regulation of genetic integrity is reprogrammed during cloning. Proc Natl Acad Sci U S A. 2009 Mar 24; 106(12):4731-5. PMID: 19255429.
      Citations: 3     Fields:    Translation:AnimalsCells
    47. Yoshioka H, McCarrey JR, Yamazaki Y. Dynamic nuclear organization of constitutive heterochromatin during fetal male germ cell development in mice. Biol Reprod. 2009 Apr; 80(4):804-12. PMID: 19129513.
      Citations: 14     Fields:    Translation:AnimalsCells
    48. McCarrey JR. Maintenance of genetic integrity during natural and assisted reproduction. Reprod Biomed Online. 2009; 18 Suppl 2:51-5. PMID: 19406032.
      Citations:    Fields:    Translation:AnimalsCells
    49. Xu M, McCarrey JR, Hecht NB. A cytoplasmic variant of the KH-type splicing regulatory protein serves as a decay-promoting factor for phosphoglycerate kinase 2 mRNA in murine male germ cells. Nucleic Acids Res. 2008 Dec; 36(22):7157-67. PMID: 19015122.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    50. Kehoe SM, Oka M, Hankowski KE, Reichert N, Garcia S, McCarrey JR, Gaubatz S, Terada N. A conserved E2F6-binding element in murine meiosis-specific gene promoters. Biol Reprod. 2008 Nov; 79(5):921-30. PMID: 18667754.
      Citations: 17     Fields:    Translation:AnimalsCells
    51. Smits G, Mungall AJ, Griffiths-Jones S, Smith P, Beury D, Matthews L, Rogers J, Pask AJ, Shaw G, VandeBerg JL, McCarrey JR, Renfree MB, Reik W, Dunham I. Conservation of the H19 noncoding RNA and H19-IGF2 imprinting mechanism in therians. Nat Genet. 2008 Aug; 40(8):971-6. PMID: 18587395.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    52. Xu G, Intano GW, McCarrey JR, Walter RB, McMahan CA, Walter CA. Recovery of a low mutant frequency after ionizing radiation-induced mutagenesis during spermatogenesis. Mutat Res. 2008 Jul 31; 654(2):150-7. PMID: 18582597.
      Citations: 9     Fields:    Translation:Animals
    53. Zhou Q, Li Y, Nie R, Friel P, Mitchell D, Evanoff RM, Pouchnik D, Banasik B, McCarrey JR, Small C, Griswold MD. Expression of stimulated by retinoic acid gene 8 (Stra8) and maturation of murine gonocytes and spermatogonia induced by retinoic acid in vitro. Biol Reprod. 2008 Mar; 78(3):537-45. PMID: 18032419.
      Citations: 86     Fields:    Translation:AnimalsCells
    54. Hornecker JL, Samollow PB, Robinson ES, Vandeberg JL, McCarrey JR. Meiotic sex chromosome inactivation in the marsupial Monodelphis domestica. Genesis. 2007 Nov; 45(11):696-708. PMID: 17987663.
      Citations: 23     Fields:    Translation:AnimalsCells
    55. Ro S, Park C, Sanders KM, McCarrey JR, Yan W. Cloning and expression profiling of testis-expressed microRNAs. Dev Biol. 2007 Nov 15; 311(2):592-602. PMID: 17936267.
      Citations: 86     Fields:    Translation:HumansAnimals
    56. Yoshioka H, Geyer CB, Hornecker JL, Patel KT, McCarrey JR. In vivo analysis of developmentally and evolutionarily dynamic protein-DNA interactions regulating transcription of the Pgk2 gene during mammalian spermatogenesis. Mol Cell Biol. 2007 Nov; 27(22):7871-85. PMID: 17875925.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    57. Ro S, Park C, Song R, Nguyen D, Jin J, Sanders KM, McCarrey JR, Yan W. Cloning and expression profiling of testis-expressed piRNA-like RNAs. RNA. 2007 Oct; 13(10):1693-702. PMID: 17698640.
      Citations: 39     Fields:    Translation:Animals
    58. Brower JV, Rodic N, Seki T, Jorgensen M, Fliess N, Yachnis AT, McCarrey JR, Oh SP, Terada N. Evolutionarily conserved mammalian adenine nucleotide translocase 4 is essential for spermatogenesis. J Biol Chem. 2007 Oct 05; 282(40):29658-66. PMID: 17681941.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    59. Iwahashi K, Yoshioka H, Low EW, McCarrey JR, Yanagimachi R, Yamazaki Y. Autonomous regulation of sex-specific developmental programming in mouse fetal germ cells. Biol Reprod. 2007 Oct; 77(4):697-706. PMID: 17615405.
      Citations: 7     Fields:    Translation:AnimalsCells
    60. Namekawa SH, VandeBerg JL, McCarrey JR, Lee JT. Sex chromosome silencing in the marsupial male germ line. Proc Natl Acad Sci U S A. 2007 Jun 05; 104(23):9730-5. PMID: 17535928.
      Citations: 45     Fields:    Translation:AnimalsCells
    61. Thomas K, Wu J, Sung DY, Thompson W, Powell M, McCarrey J, Gibbs R, Walker W. SP1 transcription factors in male germ cell development and differentiation. Mol Cell Endocrinol. 2007 May 30; 270(1-2):1-7. PMID: 17462816.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    62. Davidow LS, Breen M, Duke SE, Samollow PB, McCarrey JR, Lee JT. The search for a marsupial XIC reveals a break with vertebrate synteny. Chromosome Res. 2007; 15(2):137-46. PMID: 17333538.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    63. Caperton L, Murphey P, Yamazaki Y, McMahan CA, Walter CA, Yanagimachi R, McCarrey JR. Assisted reproductive technologies do not alter mutation frequency or spectrum. Proc Natl Acad Sci U S A. 2007 Mar 20; 104(12):5085-90. PMID: 17360354.
      Citations: 8     Fields:    Translation:AnimalsCells
    64. Liu D, Brockman JM, Dass B, Hutchins LN, Singh P, McCarrey JR, MacDonald CC, Graber JH. Systematic variation in mRNA 3'-processing signals during mouse spermatogenesis. Nucleic Acids Res. 2007; 35(1):234-46. PMID: 17158511.
      Citations: 57     Fields:    Translation:AnimalsCells
    65. Caperton L, Eddy C, Leland MM, Carey KD, McCarrey JR. Alteration of the menstrual cycle in baboons placed on tethering devices and moved to individual housing--a stress model for a follicular phase defect. J Med Primatol. 2006 Dec; 35(6):341-5. PMID: 17214661.
      Citations: 3     Fields:    Translation:Animals
    66. Namekawa SH, Park PJ, Zhang LF, Shima JE, McCarrey JR, Griswold MD, Lee JT. Postmeiotic sex chromatin in the male germline of mice. Curr Biol. 2006 Apr 04; 16(7):660-7. PMID: 16581510.
      Citations: 179     Fields:    Translation:AnimalsCells
    67. Dudley CJ, Hubbard GB, Moore CM, Dunn BG, Raveendran M, Rogers J, Nathanielsz PW, McCarrey JR, Schlabritz-Loutsevitch NE. A male baboon (Papio hamadryas) with a mosaic 43,XXY/42,XY karyotype. . 2006 Jan 01; 140(1):94-7. PMID: 16315270.
      Citations:    
    68. McCarrey JR, Geyer CB, Yoshioka H. Epigenetic regulation of testis-specific gene expression. Ann N Y Acad Sci. 2005 Dec; 1061:226-42. PMID: 16467272.
      Citations: 11     Fields:    Translation:AnimalsCells
    69. Wang PJ, Page DC, McCarrey JR. Differential expression of sex-linked and autosomal germ-cell-specific genes during spermatogenesis in the mouse. Hum Mol Genet. 2005 Oct 01; 14(19):2911-8. PMID: 16118233.
      Citations: 61     Fields:    Translation:AnimalsCells
    70. Yamazaki Y, Low EW, Marikawa Y, Iwahashi K, Bartolomei MS, McCarrey JR, Yanagimachi R. Adult mice cloned from migrating primordial germ cells. Proc Natl Acad Sci U S A. 2005 Aug 09; 102(32):11361-6. PMID: 16055553.
      Citations: 15     Fields:    Translation:AnimalsCells
    71. Xu G, Spivak G, Mitchell DL, Mori T, McCarrey JR, McMahan CA, Walter RB, Hanawalt PC, Walter CA. Nucleotide excision repair activity varies among murine spermatogenic cell types. Biol Reprod. 2005 Jul; 73(1):123-30. PMID: 15758148.
      Citations: 18     Fields:    Translation:AnimalsCells
    72. Street KA, Xu G, Hall KL, Intano GW, McCarrey JR, Herbert DC, Kilimann MW, Walter CA. Rat synapsin 1 promoter mediated transgene expression in testicular cell types. DNA Cell Biol. 2005 Feb; 24(2):133-40. PMID: 15699633.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    73. Thomas K, Sung DY, Yang J, Johnson K, Thompson W, Millette C, McCarrey J, Breitberg A, Gibbs R, Walker W. Identification, characterization, and functional analysis of sp1 transcript variants expressed in germ cells during mouse spermatogenesis. Biol Reprod. 2005 Apr; 72(4):898-907. PMID: 15601926.
      Citations: 7     Fields:    Translation:AnimalsCells
    74. Huamani J, McMahan CA, Herbert DC, Reddick R, McCarrey JR, MacInnes MI, Chen DJ, Walter CA. Spontaneous mutagenesis is enhanced in Apex heterozygous mice. Mol Cell Biol. 2004 Sep; 24(18):8145-53. PMID: 15340075.
      Citations: 31     Fields:    Translation:AnimalsCells
    75. Geyer CB, Kiefer CM, Yang TP, McCarrey JR. Ontogeny of a demethylation domain and its relationship to activation of tissue-specific transcription. Biol Reprod. 2004 Sep; 71(3):837-44. PMID: 15140797.
      Citations: 7     Fields:    Translation:AnimalsCells
    76. Walter CA, Intano GW, McMahan CA, Kelner K, McCarrey JR, Walter RB. Mutation spectral changes in spermatogenic cells obtained from old mice. DNA Repair (Amst). 2004 May 04; 3(5):495-504. PMID: 15084311.
      Citations: 10     Fields:    Translation:AnimalsCells
    77. Shima JE, McLean DJ, McCarrey JR, Griswold MD. The murine testicular transcriptome: characterizing gene expression in the testis during the progression of spermatogenesis. Biol Reprod. 2004 Jul; 71(1):319-30. PMID: 15028632.
      Citations: 193     Fields:    Translation:AnimalsCells
    78. Yamazaki Y, Mann MR, Lee SS, Marh J, McCarrey JR, Yanagimachi R, Bartolomei MS. Reprogramming of primordial germ cells begins before migration into the genital ridge, making these cells inadequate donors for reproductive cloning. Proc Natl Acad Sci U S A. 2003 Oct 14; 100(21):12207-12. PMID: 14506296.
      Citations: 49     Fields:    Translation:AnimalsCells
    79. Ding F, Patel C, Ratnam S, McCarrey JR, Chaillet JR. Conservation of Dnmt1o cytosine methyltransferase in the marsupial Monodelphis domestica. Genesis. 2003 Aug; 36(4):209-13. PMID: 12929092.
      Citations: 5     Fields:    Translation:AnimalsCells
    80. Weissig H, Narisawa S, Sikström C, Olsson PG, McCarrey JR, Tsonis PA, Del Rio-Tsonis K, Millán JL. Three novel spermatogenesis-specific zinc finger genes. FEBS Lett. 2003 Jul 17; 547(1-3):61-8. PMID: 12860387.
      Citations: 2     Fields:    Translation:AnimalsCells
    81. Walter CA, Walter RB, McCarrey JR. Germline genomes--a biological fountain of youth? Sci Aging Knowledge Environ. 2003 Feb 26; 2003(8):PE4. PMID: 12844546.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    82. McCarrey JR, Watson C, Atencio J, Ostermeier GC, Marahrens Y, Jaenisch R, Krawetz SA. X-chromosome inactivation during spermatogenesis is regulated by an Xist/Tsix-independent mechanism in the mouse. Genesis. 2002 Dec; 34(4):257-66. PMID: 12434336.
      Citations: 31     Fields:    Translation:AnimalsCells
    83. Chan J, Robinson ES, Yeh IT, McCarrey JR. Absence of ras gene mutations in UV-induced malignant melanomas correlates with a dermal origin of melanocytes in Monodelphis domestica. Cancer Lett. 2002 Oct 08; 184(1):73-80. PMID: 12104050.
      Citations: 2     Fields:    Translation:AnimalsCells
    84. Intano GW, McMahan CA, McCarrey JR, Walter RB, McKenna AE, Matsumoto Y, MacInnes MA, Chen DJ, Walter CA. Base excision repair is limited by different proteins in male germ cell nuclear extracts prepared from young and old mice. Mol Cell Biol. 2002 Apr; 22(7):2410-8. PMID: 11884623.
      Citations: 24     Fields:    Translation:AnimalsCells
    85. Wang Z, Atencio J, Robinson ES, McCarrey JR. Ultraviolet B-induced melanoma in Monodelphis domestica occurs in the absence of alterations in the structure or expression of the p53 gene. Melanoma Res. 2001 Jun; 11(3):239-45. PMID: 11468512.
      Citations: 1     Fields:    Translation:Animals
    86. Klaus AV, McCarrey JR, Farkas A, Ward WS. Changes in DNA loop domain structure during spermatogenesis and embryogenesis in the Syrian golden hamster. Biol Reprod. 2001 May; 64(5):1297-306. PMID: 11319132.
      Citations: 4     Fields:    Translation:AnimalsCells
    87. Chan J, Robinson ES, Atencio J, Wang Z, Kazianis S, Coletta LD, Nairn RS, McCarrey JR. Characterization of the CDKN2A and ARF genes in UV-induced melanocytic hyperplasias and melanomas of an opossum (Monodelphis domestica). Mol Carcinog. 2001 May; 31(1):16-26. PMID: 11398194.
      Citations: 3     Fields:    Translation:AnimalsCells
    88. Nagano M, McCarrey JR, Brinster RL. Primate spermatogonial stem cells colonize mouse testes. Biol Reprod. 2001 May; 64(5):1409-16. PMID: 11319145.
      Citations: 45     Fields:    Translation:AnimalsCells
    89. Wang PJ, McCarrey JR, Yang F, Page DC. An abundance of X-linked genes expressed in spermatogonia. Nat Genet. 2001 Apr; 27(4):422-6. PMID: 11279525.
      Citations: 249     Fields:    Translation:AnimalsCells
    90. Intano GW, McMahan CA, Walter RB, McCarrey JR, Walter CA. Mixed spermatogenic germ cell nuclear extracts exhibit high base excision repair activity. Nucleic Acids Res. 2001 Mar 15; 29(6):1366-72. PMID: 11239003.
      Citations: 13     Fields:    Translation:AnimalsCells
    91. Davis TL, Yang GJ, McCarrey JR, Bartolomei MS. The H19 methylation imprint is erased and re-established differentially on the parental alleles during male germ cell development. Hum Mol Genet. 2000 Nov 22; 9(19):2885-94. PMID: 11092765.
      Citations: 103     Fields:    Translation:AnimalsCells
    92. Kramer JA, McCarrey JR, Djakiew D, Krawetz SA. Human spermatogenesis as a model to examine gene potentiation. Mol Reprod Dev. 2000 Jun; 56(2 Suppl):254-8. PMID: 10824979.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    93. Gray TA, Smithwick MJ, Schaldach MA, Martone DL, Graves JA, McCarrey JR, Nicholls RD. Concerted regulation and molecular evolution of the duplicated SNRPB'/B and SNRPN loci. Nucleic Acids Res. 1999 Dec 01; 27(23):4577-84. PMID: 10556313.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    94. Simon I, Tenzen T, Reubinoff BE, Hillman D, McCarrey JR, Cedar H. Asynchronous replication of imprinted genes is established in the gametes and maintained during development. Nature. 1999 Oct 28; 401(6756):929-32. PMID: 10553911.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    95. McCarrey JR, O'Brien DA, Skinner MK. Construction and preliminary characterization of a series of mouse and rat testis cDNA libraries. J Androl. 1999 Sep-Oct; 20(5):635-9. PMID: 10520576.
      Citations: 8     Fields:    Translation:AnimalsCells
    96. Krawetz SA, Kramer JA, McCarrey JR. Reprogramming the male gamete genome: a window to successful gene therapy. Gene. 1999 Jun 24; 234(1):1-9. PMID: 10393233.
      Citations: 6     Fields:    Translation:AnimalsCells
    97. Zhang LP, Stroud J, Eddy CA, Walter CA, McCarrey JR. Multiple elements influence transcriptional regulation from the human testis-specific PGK2 promoter in transgenic mice. Biol Reprod. 1999 Jun; 60(6):1329-37. PMID: 10330089.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    98. Kramer JA, McCarrey JR, Djakiew D, Krawetz SA. Differentiation: the selective potentiation of chromatin domains. Development. 1998 Dec; 125(23):4749-55. PMID: 9806923.
      Citations: 19     Fields:    Translation:AnimalsCells
    99. McCarrey JR, Vandeberg JL. 9th International Congress on Isozymes, Genes, and Gene Families: an overview. J Exp Zool. 1998 Sep-Oct 1; 282(1-2):8-11. PMID: 9723160.
      Citations:    Fields:    Translation:Humans
    100. Walter CA, Intano GW, McCarrey JR, McMahan CA, Walter RB. Mutation frequency declines during spermatogenesis in young mice but increases in old mice. Proc Natl Acad Sci U S A. 1998 Aug 18; 95(17):10015-9. PMID: 9707592.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    101. McCarrey JR. Spermatogenesis as a model system for developmental analysis of regulatory mechanisms associated with tissue-specific gene expression. Semin Cell Dev Biol. 1998 Aug; 9(4):459-66. PMID: 9813193.
      Citations: 5     Fields:    Translation:HumansAnimals
    102. Zhang LP, Stroud JC, Walter CA, Adrian GS, McCarrey JR. A gene-specific promoter in transgenic mice directs testis-specific demethylation prior to transcriptional activation In vivo. Biol Reprod. 1998 Aug; 59(2):284-92. PMID: 9687297.
      Citations: 6     Fields:    Translation:AnimalsCells
    103. Mahadevaiah SK, Odorisio T, Elliott DJ, Rattigan A, Szot M, Laval SH, Washburn LL, McCarrey JR, Cattanach BM, Lovell-Badge R, Burgoyne PS. Mouse homologues of the human AZF candidate gene RBM are expressed in spermatogonia and spermatids, and map to a Y chromosome deletion interval associated with a high incidence of sperm abnormalities. Hum Mol Genet. 1998 Apr; 7(4):715-27. PMID: 9499427.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    104. Kamel D, Mackey ZB, Sjöblom T, Walter CA, McCarrey JR, Uitto L, Palosaari H, Lähdetie J, Tomkinson AE, Syväoja JE. Role of deoxyribonucleic acid polymerase epsilon in spermatogenesis in mice. Biol Reprod. 1997 Dec; 57(6):1367-74. PMID: 9408242.
      Citations: 7     Fields:    Translation:AnimalsCells
    105. Mackey ZB, Ramos W, Levin DS, Walter CA, McCarrey JR, Tomkinson AE. An alternative splicing event which occurs in mouse pachytene spermatocytes generates a form of DNA ligase III with distinct biochemical properties that may function in meiotic recombination. Mol Cell Biol. 1997 Feb; 17(2):989-98. PMID: 9001252.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    106. Odorisio T, Mahadevaiah SK, McCarrey JR, Burgoyne PS. Transcriptional analysis of the candidate spermatogenesis gene Ube1y and of the closely related Ube1x shows that they are coexpressed in spermatogonia and spermatids but are repressed in pachytene spermatocytes. Dev Biol. 1996 Nov 25; 180(1):336-43. PMID: 8948595.
      Citations: 8     Fields:    Translation:AnimalsCells
    107. Walter CA, Trolian DA, McFarland MB, Street KA, Gurram GR, McCarrey JR. Xrcc-1 expression during male meiosis in the mouse. Biol Reprod. 1996 Sep; 55(3):630-5. PMID: 8862781.
      Citations: 8     Fields:    Translation:AnimalsCells
    108. Kumari M, Stroud JC, Anji A, McCarrey JR. Differential appearance of DNase I-hypersensitive sites correlates with differential transcription of Pgk genes during spermatogenesis in the mouse. J Biol Chem. 1996 Jun 14; 271(24):14390-7. PMID: 8662942.
      Citations: 6     Fields:    Translation:AnimalsCells
    109. McCarrey JR, Kumari M, Aivaliotis MJ, Wang Z, Zhang P, Marshall F, Vandeberg JL. Analysis of the cDNA and encoded protein of the human testis-specific PGK-2 gene. Dev Genet. 1996; 19(4):321-32. PMID: 9023984.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    110. Ariel M, Robinson E, McCarrey JR, Cedar H. Gamete-specific methylation correlates with imprinting of the murine Xist gene. Nat Genet. 1995 Mar; 9(3):312-5. PMID: 7773295.
      Citations: 21     Fields:    Translation:AnimalsCells
    111. Walter CA, Lu J, Bhakta M, Zhou ZQ, Thompson LH, McCarrey JR. Testis and somatic Xrcc-1 DNA repair gene expression. Somat Cell Mol Genet. 1994 Nov; 20(6):451-61. PMID: 7892645.
      Citations: 13     Fields:    Translation:AnimalsCells
    112. Ariel M, Cedar H, McCarrey J. Developmental changes in methylation of spermatogenesis-specific genes include reprogramming in the epididymis. Nat Genet. 1994 May; 7(1):59-63. PMID: 8075642.
      Citations: 22     Fields:    Translation:AnimalsCells
    113. McCarrey JR, Williams SA. Construction of cDNA libraries from limiting amounts of material. Curr Opin Biotechnol. 1994 Feb; 5(1):34-9. PMID: 7512847.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    114. Brandeis M, Kafri T, Ariel M, Chaillet JR, McCarrey J, Razin A, Cedar H. The ontogeny of allele-specific methylation associated with imprinted genes in the mouse. EMBO J. 1993 Sep; 12(9):3669-77. PMID: 7504628.
      Citations: 65     Fields:    Translation:AnimalsCells
    115. Urven LE, Weng DE, Schumaker AL, Gearhart JD, McCarrey JR. Differential gene expression in fetal mouse germ cells. Biol Reprod. 1993 Mar; 48(3):564-74. PMID: 8452933.
      Citations: 3     Fields:    Translation:AnimalsCells
    116. McCarrey JR, Dilworth DD. Expression of Xist in mouse germ cells correlates with X-chromosome inactivation. Nat Genet. 1992 Nov; 2(3):200-3. PMID: 1345169.
      Citations: 29     Fields:    Translation:AnimalsCells
    117. McCarrey JR, Berg WM, Paragioudakis SJ, Zhang PL, Dilworth DD, Arnold BL, Rossi JJ. Differential transcription of Pgk genes during spermatogenesis in the mouse. Dev Biol. 1992 Nov; 154(1):160-8. PMID: 1426623.
      Citations: 43     Fields:    Translation:AnimalsCells
    118. McCarrey JR, Dilworth DD, Sharp RM. Semiquantitative analysis of X-linked gene expression during spermatogenesis in the mouse: ethidium-bromide staining of RT-PCR products. Genet Anal Tech Appl. 1992 Aug; 9(4):117-23. PMID: 1282026.
      Citations: 5     Fields:    Translation:AnimalsCells
    119. Dilworth DD, McCarrey JR. Single-step elimination of contaminating DNA prior to reverse transcriptase PCR. PCR Methods Appl. 1992 May; 1(4):279-82. PMID: 1282432.
      Citations: 21     Fields:    Translation:AnimalsCells
    120. Kafri T, Ariel M, Brandeis M, Shemer R, Urven L, McCarrey J, Cedar H, Razin A. Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line. Genes Dev. 1992 May; 6(5):705-14. PMID: 1577268.
      Citations: 160     Fields:    Translation:AnimalsCells
    121. Gebara MM, McCarrey JR. Protein-DNA interactions associated with the onset of testis-specific expression of the mammalian Pgk-2 gene. Mol Cell Biol. 1992 Apr; 12(4):1422-31. PMID: 1549104.
      Citations: 11     Fields:    Translation:AnimalsCells
    122. Ariel M, McCarrey J, Cedar H. Methylation patterns of testis-specific genes. Proc Natl Acad Sci U S A. 1991 Mar 15; 88(6):2317-21. PMID: 2006171.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    123. McCarrey JR. Molecular evolution of the human Pgk-2 retroposon. Nucleic Acids Res. 1990 Feb 25; 18(4):949-55. PMID: 2156237.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    124. Robinson MO, McCarrey JR, Simon MI. Transcriptional regulatory regions of testis-specific PGK2 defined in transgenic mice. Proc Natl Acad Sci U S A. 1989 Nov; 86(21):8437-41. PMID: 2813402.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    125. McCarrey JR, Kaufman JC, Churchill MA, Zaia JA. Differential detection of viral DNA and RNA in situ in cells infected with human cytomegalovirus. J Virol Methods. 1989 Sep; 25(3):301-14. PMID: 2555378.
      Citations: 1     Fields:    Translation:HumansCells
    126. Urven LE, Erickson CA, Abbott UK, McCarrey JR. Analysis of germ line development in the chick embryo using an anti-mouse EC cell antibody. Development. 1988 Jun; 103(2):299-304. PMID: 2465117.
      Citations: 8     Fields:    Translation:AnimalsCells
    127. McCarrey JR, Thomas K. Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene. Nature. 1987 Apr 2-8; 326(6112):501-5. PMID: 3453121.
      Citations: 120     Fields:    Translation:HumansCells
    128. McCarrey JR, Hsu KC, Eddy EM, Klevecz RR, Bolen JL. Isolation of viable mouse primordial germ cells by antibody-directed flow sorting. J Exp Zool. 1987 Apr; 242(1):107-11. PMID: 3598509.
      Citations: 5     Fields:    Translation:AnimalsCells
    129. McCarrey JR. Nucleotide sequence of the promoter region of a tissue-specific human retroposon: comparison with its housekeeping progenitor. Gene. 1987; 61(3):291-8. PMID: 3446575.
      Citations: 14     Fields:    Translation:AnimalsCells
    130. McCarrey JR, Riggs AD. Determinator-inhibitor pairs as a mechanism for threshold setting in development: a possible function for pseudogenes. Proc Natl Acad Sci U S A. 1986 Feb; 83(3):679-83. PMID: 2418440.
      Citations: 20     Fields:    Translation:Animals
    131. Riggins RS, Lewis DA, Benson DR, McCarrey JR, Franti CE. Mechanical properties of the tibia from chickens with idiopathic scoliosis. J Biomech. 1983; 16(1):59-67. PMID: 6833310.
      Citations:    Fields:    Translation:Animals
    132. Epplen JT, McCarrey JR, Sutou S, Ohno S. Base sequence of a cloned snake W-chromosome DNA fragment and identification of a male-specific putative mRNA in the mouse. Proc Natl Acad Sci U S A. 1982 Jun; 79(12):3798-802. PMID: 6954524.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    133. McCarrey JR, Abbott UK. Functional differentiation of chick gonads following depletion of primordial germ cells. J Embryol Exp Morphol. 1982 Apr; 68:161-74. PMID: 7108420.
      Citations: 1     Fields:    Translation:AnimalsCells
    134. Epplen JT, Sutou S, McCarrey JR, Ohno S. Is sex-specifically arranged repetitive DNA involved in primary sex determination of vertebrates? Prog Clin Biol Res. 1982; 103 Pt A:317-26. PMID: 7163202.
      Citations: 1     Fields:    Translation:AnimalsCells
    135. McCarrey JR, Abplanalp H, Abbott UK. Studies on the H-W (H-Y) antigen in chickens. Evidence for H-W monomorphism and line specific restriction of graft rejection. J Hered. 1981 May-Jun; 72(3):169-71. PMID: 7024399.
      Citations: 2     Fields:    Translation:AnimalsCells
    136. McCarrey JR, Abbott UK, Benson DR, Riggins RS. Genetics of scoliosis in chickens. J Hered. 1981 Jan-Feb; 72(1):6-10. PMID: 7204941.
      Citations: 7     Fields:    Translation:Animals
    137. McCarrey JR, Abbott UK. Mechanisms of genetic sex determination, gonadal sex differentiation, and germ-cell development in animals. Adv Genet. 1979; 20:217-90. PMID: 390998.
      Citations: 6     Fields:    Translation:AnimalsCells
    138. McCarrey JR, Abbott UK. Chick gonad differentiation following excision of primordial germ cells. Dev Biol. 1978 Sep; 66(1):256-65. PMID: 751839.
      Citations: 2     Fields:    Translation:AnimalsCells
    139. Riggins RS, Abbott UK, Ashmore CR, Rucker RB, McCarrey JR. Scoliosis in chickens. J Bone Joint Surg Am. 1977 Dec; 59(8):1020-6. PMID: 591531.
      Citations: 2     Fields:    Translation:Animals
    140. MacCabe JA, MacCabe AB, Abbott UK, McCarrey JR. Limb development in diplopodia4: a polydactylous mutation in the chicken. J Exp Zool. 1975 Mar; 191(3):383-94. PMID: 1127402.
      Citations:    Fields:    Translation:Animals
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