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Connection

Jayalakshmi Sridhar to Humans

This is a "connection" page, showing publications Jayalakshmi Sridhar has written about Humans.
Connection Strength

0.305
  1. Sridhar J, Goyal N, Liu J, Foroozesh M. Review of Ligand Specificity Factors for CYP1A Subfamily Enzymes from Molecular Modeling Studies Reported to-Date. Molecules. 2017 Jul 08; 22(7).
    View in: PubMed
    Score: 0.028
  2. Sridhar J, Liu J, Komati R, Schroeder R, Jiang Q, Tram P, Riley K, Foroozesh M. Ortho-Methylarylamines as Time-Dependent Inhibitors of Cytochrome P450 1A1 Enzyme. Drug Metab Lett. 2017; 10(4):270-277.
    View in: PubMed
    Score: 0.027
  3. Schroeder RL, Goyal N, Bratton M, Townley I, Pham NA, Tram P, Stone T, Geathers J, Nguyen K, Sridhar J. Identification of quinones as novel PIM1 kinase inhibitors. Bioorg Med Chem Lett. 2016 07 01; 26(13):3187-3191.
    View in: PubMed
    Score: 0.026
  4. Schroeder RL, Tram P, Liu J, Foroozesh M, Sridhar J. Novel functionalized 5-(phenoxymethyl)-1,3-dioxane analogs exhibiting cytochrome P450 inhibition: a patent evaluation WO2015048311 (A1). Expert Opin Ther Pat. 2016; 26(1):139-47.
    View in: PubMed
    Score: 0.025
  5. Schroeder RL, Stevens CL, Sridhar J. Small molecule tyrosine kinase inhibitors of ErbB2/HER2/Neu in the treatment of aggressive breast cancer. Molecules. 2014 Sep 23; 19(9):15196-212.
    View in: PubMed
    Score: 0.023
  6. Sridhar J, Sfondouris ME, Bratton MR, Nguyen TL, Townley I, Klein Stevens CL, Jones FE. Identification of quinones as HER2 inhibitors for the treatment of trastuzumab resistant breast cancer. Bioorg Med Chem Lett. 2014 Jan 01; 24(1):126-31.
    View in: PubMed
    Score: 0.022
  7. Sridhar J, Liu J, Foroozesh M, Stevens CL. Insights on cytochrome p450 enzymes and inhibitors obtained through QSAR studies. Molecules. 2012 Aug 03; 17(8):9283-305.
    View in: PubMed
    Score: 0.020
  8. Sridhar J, Liu J, Foroozesh M, Klein Stevens CL. Inhibition of cytochrome p450 enzymes by quinones and anthraquinones. Chem Res Toxicol. 2012 Feb 20; 25(2):357-65.
    View in: PubMed
    Score: 0.019
  9. Sridhar J, Jin P, Liu J, Foroozesh M, Stevens CL. In silico studies of polyaromatic hydrocarbon inhibitors of cytochrome P450 enzymes 1A1, 1A2, 2A6, and 2B1. Chem Res Toxicol. 2010 Mar 15; 23(3):600-7.
    View in: PubMed
    Score: 0.017
  10. Sridhar J, Akula N, Pattabiraman N. Selectivity and potency of cyclin-dependent kinase inhibitors. AAPS J. 2006 Mar 24; 8(1):E204-21.
    View in: PubMed
    Score: 0.013
  11. Sridhar J, Akula N, Sivanesan D, Narasimhan M, Rathinavelu A, Pattabiraman N. Identification of novel angiogenesis inhibitors. Bioorg Med Chem Lett. 2005 Sep 15; 15(18):4125-9.
    View in: PubMed
    Score: 0.012
  12. Goyal N, Do C, Sridhar J, Shaik S, Thompson A, Perry T, Carter L, Foroozesh M. Design, Synthesis, and Biological Studies of Flavone-Based Esters and Acids as Potential P450 2A6 Inhibitors. Chem Res Toxicol. 2023 12 18; 36(12):1973-1979.
    View in: PubMed
    Score: 0.011
  13. Sridhar J, Wei ZL, Nowak I, Lewin NE, Ayres JA, Pearce LV, Blumberg PM, Kozikowski AP. New bivalent PKC ligands linked by a carbon spacer: enhancement in binding affinity. J Med Chem. 2003 Sep 11; 46(19):4196-204.
    View in: PubMed
    Score: 0.011
  14. Foroozesh M, Sridhar J, Goyal N, Liu J. Coumarins and P450s, Studies Reported to-Date. Molecules. 2019 Apr 24; 24(8).
    View in: PubMed
    Score: 0.008
  15. Bateman ME, Strong AL, Hunter RS, Bratton MR, Komati R, Sridhar J, Riley KE, Wang G, Hayes DJ, Boue SM, Burow ME, Bunnell BA. Osteoinductive effects of glyceollins on adult mesenchymal stromal/stem cells from adipose tissue and bone marrow. Phytomedicine. 2017 Apr 15; 27:39-51.
    View in: PubMed
    Score: 0.007
  16. Komati R, Spadoni D, Zheng S, Sridhar J, Riley KE, Wang G. Ligands of Therapeutic Utility for the Liver X Receptors. Molecules. 2017 Jan 05; 22(1).
    View in: PubMed
    Score: 0.007
  17. Zheng S, Zhong Q, Xi Y, Mottamal M, Zhang Q, Schroeder RL, Sridhar J, He L, McFerrin H, Wang G. Modification and biological evaluation of thiazole derivatives as novel inhibitors of metastatic cancer cell migration and invasion. J Med Chem. 2014 Aug 14; 57(15):6653-67.
    View in: PubMed
    Score: 0.006
  18. Liu J, Sridhar J, Foroozesh M. Cytochrome P450 family 1 inhibitors and structure-activity relationships. Molecules. 2013 Nov 25; 18(12):14470-95.
    View in: PubMed
    Score: 0.005
  19. Liu J, Taylor SF, Dupart PS, Arnold CL, Sridhar J, Jiang Q, Wang Y, Skripnikova EV, Zhao M, Foroozesh M. Pyranoflavones: a group of small-molecule probes for exploring the active site cavities of cytochrome P450 enzymes 1A1, 1A2, and 1B1. J Med Chem. 2013 May 23; 56(10):4082-92.
    View in: PubMed
    Score: 0.005
  20. Liu J, Nguyen TT, Dupart PS, Sridhar J, Zhang X, Zhu N, Stevens CL, Foroozesh M. 7-Ethynylcoumarins: selective inhibitors of human cytochrome P450s 1A1 and 1A2. Chem Res Toxicol. 2012 May 21; 25(5):1047-57.
    View in: PubMed
    Score: 0.005
  21. Jiang Q, Payton-Stewart F, Elliott S, Driver J, Rhodes LV, Zhang Q, Zheng S, Bhatnagar D, Boue SM, Collins-Burow BM, Sridhar J, Stevens C, McLachlan JA, Wiese TE, Burow ME, Wang G. Effects of 7-O substitutions on estrogenic and anti-estrogenic activities of daidzein analogues in MCF-7 breast cancer cells. J Med Chem. 2010 Aug 26; 53(16):6153-63.
    View in: PubMed
    Score: 0.004
  22. Kozikowski AP, Gaisina IN, Petukhov PA, Sridhar J, King LT, Blond SY, Duka T, Rusnak M, Sidhu A. Highly potent and specific GSK-3beta inhibitors that block tau phosphorylation and decrease alpha-synuclein protein expression in a cellular model of Parkinson's disease. ChemMedChem. 2006 Feb; 1(2):256-66.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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