HSP27 Heat-Shock Proteins

"HSP27 Heat-Shock Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

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A subfamily of small heat-shock proteins that function as molecular chaperones that aid in refolding of non-native proteins. They play a protective role that increases cellular survival during times of stress.

Descriptor ID	D055551
MeSH Number(s)	D12.776.580.216.270.625
Concept/Terms	HSP27 Heat-Shock Proteins HSP27 Heat-Shock Proteins HSP27 Heat Shock Proteins Heat-Shock Proteins, HSP27 HSP27 Protein HSP27 Proteins Heat Shock Protein beta-1 Heat Shock Protein beta 1 Heat-Shock Protein 27 Heat Shock Protein 27 Protein 27, Heat-Shock Heat-Shock Proteins 27 Heat Shock Proteins 27

Below are MeSH descriptors whose meaning is more general than "HSP27 Heat-Shock Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Molecular Chaperones [D12.776.580]
Heat-Shock Proteins [D12.776.580.216]
Heat-Shock Proteins, Small [D12.776.580.216.270]
HSP27 Heat-Shock Proteins [D12.776.580.216.270.625]

Below are MeSH descriptors whose meaning is related to "HSP27 Heat-Shock Proteins".

Below are MeSH descriptors whose meaning is more specific than "HSP27 Heat-Shock Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "HSP27 Heat-Shock Proteins" by people in this website by year, and whether "HSP27 Heat-Shock Proteins" was a major or minor topic of these publications.

Bar chart showing 8 publications over 6 distinct years, with a maximum of 2 publications in 2010 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2007	0	1	1
2010	1	1	2
2011	0	1	1
2017	0	1	1
2018	2	0	2
2021	0	1	1

Below are the most recent publications written about "HSP27 Heat-Shock Proteins" by people in Profiles.

Ochoa PT, Sanchez-Hernandez ES, Duran AM, Cheng KW, Philip J, Suzuki T, Unternaehrer JJ, Dutil J, Das B, Ganguly R, Baca Y, de Semir D, Wang C, Kremsky I, Casiano CA. The GR-LEDGF/p75-HSP27 Axis Contributes to Cross-Resistance Between Enzalutamide and Docetaxel in Prostate Cancer. Cells. 2025 Oct 09; 14(19).

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Peng Z, Bedi S, Mann V, Sundaresan A, Homma K, Gaskey G, Kowada M, Umar S, Kulkarni AD, Eltzschig HK, Doursout MF. Neuroprotective Effects of Asparagus officinalis Stem Extract in Transgenic Mice Overexpressing Amyloid Precursor Protein. J Immunol Res. 2021; 2021:8121407.

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Livingston JA, Wang WL, Tsai JW, Lazar AJ, Leung CH, Lin H, Advani S, Daw N, Santiago-O'Farrill J, Hollomon M, Gordon NB, Kleinerman ES. Analysis of HSP27 and the Autophagy Marker LC3B+ Puncta Following Preoperative Chemotherapy Identifies High-Risk Osteosarcoma Patients. Mol Cancer Ther. 2018 06; 17(6):1315-1323.

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Zhang C, Jones JT, Chand HS, Wathelet MG, Evans CM, Dickey B, Xiang J, Mebratu YA, Tesfaigzi Y. Noxa/HSP27 complex delays degradation of ubiquitylated IkBa in airway epithelial cells to reduce pulmonary inflammation. Mucosal Immunol. 2018 05; 11(3):741-751.

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Joshi JB, Patel D, Morton DJ, Sharma P, Zou J, Hewa Bostanthirige D, Gorantla Y, Nagappan P, Komaragiri SK, Sivils JC, Xie H, Palaniappan R, Wang G, Cox MB, Chaudhary J. Inactivation of ID4 promotes a CRPC phenotype with constitutive AR activation through FKBP52. Mol Oncol. 2017 04; 11(4):337-357.

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Fung KY, Brierley GV, Henderson S, Hoffmann P, McColl SR, Lockett T, Head R, Cosgrove L. Butyrate-induced apoptosis in HCT116 colorectal cancer cells includes induction of a cell stress response. J Proteome Res. 2011 Apr 01; 10(4):1860-9.

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Wang H, Yang Y, Sharma N, Tarasova NI, Timofeeva OA, Winkler-Pickett RT, Tanigawa S, Perantoni AO. STAT1 activation regulates proliferation and differentiation of renal progenitors. Cell Signal. 2010 Nov; 22(11):1717-26.

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Bueno MT, Garcia-Rivera JA, Kugelman JR, Morales E, Rosas-Acosta G, Llano M. SUMOylation of the lens epithelium-derived growth factor/p75 attenuates its transcriptional activity on the heat shock protein 27 promoter. J Mol Biol. 2010 Jun 04; 399(2):221-39.

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Achanta P, Thompson KJ, Fuss M, Martinez JL. Gene expression changes in the rodent hippocampus following whole brain irradiation. Neurosci Lett. 2007 May 17; 418(2):143-8.

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Cubano LA, Lewis ML. Effect of vibrational stress and spaceflight on regulation of heat shock proteins hsp70 and hsp27 in human lymphocytes (Jurkat). J Leukoc Biol. 2001 May; 69(5):755-61.

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