"Dioxygenases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-heme iron-containing enzymes that incorporate two atoms of OXYGEN into the substrate. They are important in biosynthesis of FLAVONOIDS; GIBBERELLINS; and HYOSCYAMINE; and for degradation of AROMATIC HYDROCARBONS.
| Descriptor ID |
D049308
|
| MeSH Number(s) |
D08.811.682.690.416
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Dioxygenases".
Below are MeSH descriptors whose meaning is more specific than "Dioxygenases".
This graph shows the total number of publications written about "Dioxygenases" by people in this website by year, and whether "Dioxygenases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Dioxygenases" by people in Profiles.
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Chuang TD, Ton N, Rysling S, Quintanilla D, Boos D, Khorram O. Therapeutic effects of in?vivo administration of an inhibitor of tryptophan 2,3-dioxygenase (680c91) for the treatment of fibroids: a preclinical study. Fertil Steril. 2024 Apr; 121(4):669-678.
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Nadar VS, Kandavelu P, Sankaran B, Rosen BP, Yoshinaga M. The ArsI C-As lyase: Elucidating the catalytic mechanism of degradation of organoarsenicals. J Inorg Biochem. 2022 07; 232:111836.
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Wang Y, Davis I, Chan Y, Naik SG, Griffith WP, Liu A. Characterization of the nonheme iron center of cysteamine dioxygenase and its interaction with substrates. J Biol Chem. 2020 08 14; 295(33):11789-11802.
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Wang Y, Griffith WP, Li J, Koto T, Wherritt DJ, Fritz E, Liu A. Cofactor Biogenesis in Cysteamine Dioxygenase: C-F Bond Cleavage with Genetically Incorporated Unnatural Tyrosine. Angew Chem Int Ed Engl. 2018 07 02; 57(27):8149-8153.
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Nadar VS, Yoshinaga M, Pawitwar SS, Kandavelu P, Sankaran B, Rosen BP. Structure of the ArsI C-As Lyase: Insights into the Mechanism of Degradation of Organoarsenical Herbicides and Growth Promoters. J Mol Biol. 2016 06 05; 428(11):2462-2473.
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Yoshinaga M, Rosen BP. A C?As lyase for degradation of environmental organoarsenical herbicides and animal husbandry growth promoters. Proc Natl Acad Sci U S A. 2014 May 27; 111(21):7701-6.
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Tittabutr P, Cho IK, Li QX. Phn and Nag-like dioxygenases metabolize polycyclic aromatic hydrocarbons in Burkholderia sp. C3. Biodegradation. 2011 Nov; 22(6):1119-33.
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Ullmann BD, Myers H, Chiranand W, Lazzell AL, Zhao Q, Vega LA, Lopez-Ribot JL, Gardner PR, Gustin MC. Inducible defense mechanism against nitric oxide in Candida albicans. Eukaryot Cell. 2004 Jun; 3(3):715-23.
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Boyd DR, Sharma ND, Kennedy MA, Shepherd SD, Malone JF, Alves-Areias A, Holt R, Allenmark SG, Lemurell MA, Dalton H, Luckarift H. Enzyme-catalysed oxygenation and deoxygenation routes to chiral thiosulfinates. Chem Commun (Camb). 2002 Jul 21; (14):1452-3.