"Genomic Islands" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Distinct units in some bacterial, bacteriophage or plasmid GENOMES that are types of MOBILE GENETIC ELEMENTS. Encoded in them are a variety of fitness conferring genes, such as VIRULENCE FACTORS (in "pathogenicity islands or islets"), ANTIBIOTIC RESISTANCE genes, or genes required for SYMBIOSIS (in "symbiosis islands or islets"). They range in size from 10 - 500 kilobases, and their GC CONTENT and CODON usage differ from the rest of the genome. They typically contain an INTEGRASE gene, although in some cases this gene has been deleted resulting in "anchored genomic islands".
Descriptor ID |
D044404
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MeSH Number(s) |
G02.111.570.080.708.330.330 G05.360.080.708.330.330 G05.360.340.024.425.500
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Concept/Terms |
Genomic Islands- Genomic Islands
- Genomic Island
- Island, Genomic
- Islands, Genomic
Genomic Islets- Genomic Islets
- Genomic Islet
- Islet, Genomic
- Islets, Genomic
Symbiosis Islets- Symbiosis Islets
- Islet, Symbiosis
- Islets, Symbiosis
- Symbiosis Islet
Pathogenicity Islets- Pathogenicity Islets
- Islet, Pathogenicity
- Islets, Pathogenicity
- Pathogenicity Islet
Symbiosis Islands- Symbiosis Islands
- Island, Symbiosis
- Islands, Symbiosis
- Symbiosis Island
Anchored Genomic Islands- Anchored Genomic Islands
- Anchored Genomic Island
- Genomic Island, Anchored
- Genomic Islands, Anchored
- Island, Anchored Genomic
- Islands, Anchored Genomic
Pathogenicity Islands- Pathogenicity Islands
- Island, Pathogenicity
- Islands, Pathogenicity
- Pathogenicity Island
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Below are MeSH descriptors whose meaning is more general than "Genomic Islands".
Below are MeSH descriptors whose meaning is more specific than "Genomic Islands".
This graph shows the total number of publications written about "Genomic Islands" by people in this website by year, and whether "Genomic Islands" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 1 | 0 | 1 |
2005 | 1 | 1 | 2 |
2007 | 1 | 2 | 3 |
2008 | 1 | 0 | 1 |
2009 | 2 | 0 | 2 |
2011 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Genomic Islands" by people in Profiles.
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Ou HY, Kuang SN, He X, Molgora BM, Ewing PJ, Deng Z, Osby M, Chen W, Xu HH. Complete genome sequence of hypervirulent and outbreak-associated Acinetobacter baumannii strain LAC-4: epidemiology, resistance genetic determinants and potential virulence factors. Sci Rep. 2015 Mar 02; 5:8643.
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Eppinger M, Mammel MK, Leclerc JE, Ravel J, Cebula TA. Genomic anatomy of Escherichia coli O157:H7 outbreaks. Proc Natl Acad Sci U S A. 2011 Dec 13; 108(50):20142-7.
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Barker JR, Chong A, Wehrly TD, Yu JJ, Rodriguez SA, Liu J, Celli J, Arulanandam BP, Klose KE. The Francisella tularensis pathogenicity island encodes a secretion system that is required for phagosome escape and virulence. Mol Microbiol. 2009 Dec; 74(6):1459-70.
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Cong Y, Yu JJ, Guentzel MN, Berton MT, Seshu J, Klose KE, Arulanandam BP. Vaccination with a defined Francisella tularensis subsp. novicida pathogenicity island mutant (DeltaiglB) induces protective immunity against homotypic and heterotypic challenge. Vaccine. 2009 Sep 18; 27(41):5554-61.
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Chong A, Wehrly TD, Nair V, Fischer ER, Barker JR, Klose KE, Celli J. The early phagosomal stage of Francisella tularensis determines optimal phagosomal escape and Francisella pathogenicity island protein expression. Infect Immun. 2008 Dec; 76(12):5488-99.
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Eppinger M, Rosovitz MJ, Fricke WF, Rasko DA, Kokorina G, Fayolle C, Lindler LE, Carniel E, Ravel J. The complete genome sequence of Yersinia pseudotuberculosis IP31758, the causative agent of Far East scarlet-like fever. PLoS Genet. 2007 Aug; 3(8):e142.
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Santic M, Molmeret M, Barker JR, Klose KE, Dekanic A, Doric M, Abu Kwaik Y. A Francisella tularensis pathogenicity island protein essential for bacterial proliferation within the host cell cytosol. Cell Microbiol. 2007 Oct; 9(10):2391-403.
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Barker JR, Klose KE. Molecular and genetic basis of pathogenesis in Francisella tularensis. Ann N Y Acad Sci. 2007 Jun; 1105:138-59.
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Santic M, Molmeret M, Klose KE, Jones S, Kwaik YA. The Francisella tularensis pathogenicity island protein IglC and its regulator MglA are essential for modulating phagosome biogenesis and subsequent bacterial escape into the cytoplasm. Cell Microbiol. 2005 Jul; 7(7):969-79.
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Porter ME, Mitchell P, Free A, Smith DG, Gally DL. The LEE1 promoters from both enteropathogenic and enterohemorrhagic Escherichia coli can be activated by PerC-like proteins from either organism. J Bacteriol. 2005 Jan; 187(2):458-72.