"Integrin beta Chains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Integrin beta chains combine with integrin alpha chains to form heterodimeric cell surface receptors. Integrins have traditionally been classified into functional groups based on the identity of one of three beta chains present in the heterodimer. The beta chain is necessary and sufficient for integrin-dependent signaling. Its short cytoplasmic tail contains sequences critical for inside-out signaling.
Descriptor ID |
D039641
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MeSH Number(s) |
D12.776.543.750.705.408.200
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Concept/Terms |
Integrin beta Chains- Integrin beta Chains
- beta Chains, Integrin
- Integrin beta Subunits
- beta Integrins
- Integrins, beta
|
Below are MeSH descriptors whose meaning is more general than "Integrin beta Chains".
Below are MeSH descriptors whose meaning is more specific than "Integrin beta Chains".
This graph shows the total number of publications written about "Integrin beta Chains" by people in this website by year, and whether "Integrin beta Chains" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 1 | 0 | 1 |
2015 | 2 | 0 | 2 |
2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Integrin beta Chains" by people in Profiles.
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Kumar V, Soni UK, Maurya VK, Singh K, Jha RK. Integrin beta8 (ITGB8) activates VAV-RAC1 signaling via FAK in the acquisition of endometrial epithelial cell receptivity for blastocyst implantation. Sci Rep. 2017 05 15; 7(1):1885.
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Aslan B, Monroig P, Hsu MC, Pena GA, Rodriguez-Aguayo C, Gonzalez-Villasana V, Rupaimoole R, Nagaraja AS, Mangala S, Han HD, Yuca E, Wu SY, Ivan C, Moss TJ, Ram PT, Wang H, Gol-Chambers A, Ozkayar O, Kanlikilicer P, Fuentes-Mattei E, Kahraman N, Pradeep S, Ozpolat B, Tucker S, Hung MC, Baggerly K, Bartholomeusz G, Calin G, Sood AK, Lopez-Berestein G. The ZNF304-integrin axis protects against anoikis in cancer. Nat Commun. 2015 Jun 17; 6:7351.
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Kumar V, Maurya VK, Joshi A, Meeran SM, Jha RK. Integrin beta 8 (ITGB8) regulates embryo implantation potentially via controlling the activity of TGF-B1 in mice. Biol Reprod. 2015 Apr; 92(4):109.
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Edwards JP, Thornton AM, Shevach EM. Release of active TGF-?1 from the latent TGF-?1/GARP complex on T regulatory cells is mediated by integrin ?8. J Immunol. 2014 Sep 15; 193(6):2843-9.