"Photoaffinity Labels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Biologically active molecules which are covalently bound to the enzymes or binding proteins normally acting on them. Binding occurs due to activation of the label by ultraviolet light. These labels are used primarily to identify binding sites on proteins.
| Descriptor ID |
D019920
|
| MeSH Number(s) |
D27.720.470.410.080.600
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Photoaffinity Labels".
Below are MeSH descriptors whose meaning is more specific than "Photoaffinity Labels".
This graph shows the total number of publications written about "Photoaffinity Labels" by people in this website by year, and whether "Photoaffinity Labels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Photoaffinity Labels" by people in Profiles.
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Kawamura A, Washington I, Mihai DM, Bartolini F, Gundersen GG, Mark MT, Nakanishi K. Identification of ginkgolide targets in brain by photoaffinity labeling. Chem Biol Drug Des. 2017 04; 89(4):475-481.
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Kuang YH, Patel JP, Sodani K, Wu CP, Liao LQ, Patel A, Tiwari AK, Dai CL, Chen X, Fu LW, Ambudkar SV, Korlipara VL, Chen ZS. OSI-930 analogues as novel reversal agents for ABCG2-mediated multidrug resistance. Biochem Pharmacol. 2012 Sep 15; 84(6):766-74.
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Balas L, Durand T, Saha S, Johnson I, Mukhopadhyay S. Total synthesis of photoactivatable or fluorescent anandamide probes: novel bioactive compounds with angiogenic activity. J Med Chem. 2009 Feb 26; 52(4):1005-17.
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Kawamura A, Hindi S, Mihai DM, James L, Aminova O. Binding is not enough: flexibility is needed for photocrosslinking of Lck kinase by benzophenone photoligands. Bioorg Med Chem. 2008 Oct 01; 16(19):8824-9.