"Antigens, CD45" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopoietic progenitors. They contain two FIBRONECTIN TYPE III DOMAINS and possess cytoplasmic protein tyrosine phosphatase activity, which plays a role in intracellular signaling from the CELL SURFACE RECEPTORS. Leukocyte common antigens occur as multiple isoforms that result from alternative mRNA splicing and differential usage of three exons.
Descriptor ID |
D017493
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MeSH Number(s) |
D08.811.277.352.650.775.400.100.500 D12.644.360.587.100.500 D12.776.476.592.100.500 D12.776.543.733.937.500
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Concept/Terms |
Leukocyte Common Antigens- Leukocyte Common Antigens
- Antigens, Leukocyte Common
- CD45 Antigens
- Antigens, CD45
- Protein Tyrosine Phosphatase, Receptor Type, C
- L-CA Antigens
- Antigens, L-CA
- L CA Antigens
- Leukocyte Common Antigen
- Antigen, Leukocyte Common
- CD45 Antigen
- Antigen, CD45
- T200 Antigens
- Antigens, T200
CD45RO Antigens- CD45RO Antigens
- Antigens, CD45RO
- CD45R0 Antigens
- Antigens, CD45R0
B220 Antigens- B220 Antigens
- Antigens, B220
- CD45R Antigens
- Antigens, CD45R
- B220 Antigen
- Antigen, B220
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Below are MeSH descriptors whose meaning is more general than "Antigens, CD45".
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