Paclitaxel

"Paclitaxel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes MICROTUBULES in their polymerized form leading to cell death.

Descriptor ID	D017239
MeSH Number(s)	D02.455.426.392.368.242.888.777 D02.455.849.291.850.777
Concept/Terms	Paclitaxel Paclitaxel Anzatax Anzatax NSC-125973 NSC-125973 NSC 125973 NSC125973 Taxol Taxol Taxol A Bris Taxol Taxol, Bris Paclitaxel, (4 alpha)-Isomer Paclitaxel, (4 alpha)-Isomer Paxene Paxene Praxel Praxel 7-epi-Taxol 7-epi-Taxol 7 epi Taxol Onxol Onxol

Below are MeSH descriptors whose meaning is more general than "Paclitaxel".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Hydrocarbons [D02.455]
Hydrocarbons, Cyclic [D02.455.426]
Hydrocarbons, Alicyclic [D02.455.426.392]
Cycloparaffins [D02.455.426.392.368]
Cyclodecanes [D02.455.426.392.368.242]
Taxoids [D02.455.426.392.368.242.888]
Paclitaxel [D02.455.426.392.368.242.888.777]
Terpenes [D02.455.849]
Diterpenes [D02.455.849.291]
Taxoids [D02.455.849.291.850]
Paclitaxel [D02.455.849.291.850.777]

Below are MeSH descriptors whose meaning is related to "Paclitaxel".

Below are MeSH descriptors whose meaning is more specific than "Paclitaxel".

Paclitaxel
Albumin-Bound Paclitaxel

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Paclitaxel" by people in this website by year, and whether "Paclitaxel" was a major or minor topic of these publications.

Bar chart showing 51 publications over 22 distinct years, with a maximum of 4 publications in 2004 and 2010 and 2014 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2003	1	0	1
2004	0	4	4
2005	1	1	2
2006	1	2	3
2008	0	2	2
2009	1	2	3
2010	1	3	4
2011	2	1	3
2012	1	1	2
2014	3	1	4
2015	0	2	2
2016	1	0	1
2017	1	1	2
2018	1	1	2
2019	2	2	4
2020	1	1	2
2021	1	1	2
2022	0	1	1
2023	0	2	2
2024	2	0	2
2025	0	2	2

Below are the most recent publications written about "Paclitaxel" by people in Profiles.

Aare M, Padakanti SC, Singh M. In Vivo Pharmacodynamic and Pharmacokinetic Assessment of Cannabidiol-loaded Camel Milk Exosomes in Doxorubicin-resistant Triple-negative Breast Cancer Xenografts. AAPS PharmSciTech. 2025 Sep 11; 26(7):227.

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Aare M, Lazarte JMS, Muthu M, Rishi AK, Singh M. Genetically bio-engineered PD-L1 targeted exosomes for immunotherapy of resistant triple negative breast cancer. Drug Deliv Transl Res. 2026 Feb; 16(2):693-710.

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Cruz-Collazo AM, Katsara O, Grafals-Ruiz N, Colon Gonzalez J, Dorta-Estremera S, Carlo VP, Chorna N, Schneider RJ, Dharmawardhane S. Novel Inhibition of Central Carbon Metabolism Pathways by Rac and CDC42 inhibitor MBQ167 and Paclitaxel. Mol Cancer Ther. 2024 Nov 04; 23(11):1613-1625.

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Ngo AN, Chatman KK, Douglas D, Mosley-Kellum KM, Wu K, Vadgama J. Engineering of layer-by-layer acetate-coated paclitaxel loaded poly(lactide-co-glycolide) acid nanoparticles for prostate cancer therapy- in vitro. J Pharm Sci. 2024 Nov; 113(11):3375-3383.

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McFadden M, Singh SK, Kinnel B, Varambally S, Singh R. The effect of paclitaxel- and fisetin-loaded PBM nanoparticles on apoptosis and reversal of drug resistance gene ABCG2 in ovarian cancer. J Ovarian Res. 2023 Nov 21; 16(1):220.

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Rosenthal MD, Schmidt LA, Vargas R, Blacker LS, McCulloch CE, Ezennia J, Patel AI. Drink Tap: A Multisector Program to Promote Water Access and Intake in San Francisco Parks. Prev Chronic Dis. 2023 08 24; 20:E74.

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Kumar Kalvala A, Bagde A, Arthur P, Kumar Surapaneni S, Ramesh N, Nathani A, Singh M. Role of Cannabidiol and Tetrahydrocannabivarin on Paclitaxel-induced neuropathic pain in rodents. Int Immunopharmacol. 2022 Jun; 107:108693.

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Gangapuram M, Mazzio EA, Redda KK, Soliman KFA. Transcriptome Profile Analysis of Triple-Negative Breast Cancer Cells in Response to a Novel Cytostatic Tetrahydroisoquinoline Compared to Paclitaxel. Int J Mol Sci. 2021 Jul 19; 22(14).

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Moore KN, Bookman M, Sehouli J, Miller A, Anderson C, Scambia G, Myers T, Taskiran C, Robison K, M?enp?? J, Willmott L, Colombo N, Thomes-Pepin J, Liontos M, Gold MA, Garcia Y, Sharma SK, Darus CJ, Aghajanian C, Okamoto A, Wu X, Safin R, Wu F, Molinero L, Maiya V, Khor VK, Lin YG, Pignata S. Atezolizumab, Bevacizumab, and Chemotherapy for Newly Diagnosed Stage III or IV Ovarian Cancer: Placebo-Controlled Randomized Phase III Trial (IMagyn050/GOG 3015/ENGOT-OV39). J Clin Oncol. 2021 06 10; 39(17):1842-1855.

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Patel JD, Lee JW, Carbone DP, Wagner H, Shanker A, de Aquino MTP, Horn L, Johnson ML, Gerber DE, Liu JJ, Das MS, Al-Nsour MA, Dakhil CSR, Ramalingam S, Schiller JH. Phase II Study of Immunotherapy With Tecemotide and Bevacizumab After Chemoradiation in Patients With Unresectable Stage III Non-Squamous Non-Small-Cell Lung?Cancer (NS-NSCLC): A Trial of the ECOG-ACRIN Cancer Research Group (E6508). Clin Lung Cancer. 2020 11; 21(6):520-526.

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