"Enalaprilat" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The active metabolite of ENALAPRIL and one of the potent, intravenously administered, ANGIOTENSIN-CONVERTING ENZYME INHIBITORS. It is an effective agent for the treatment of essential hypertension and has beneficial hemodynamic effects in heart failure. The drug produces renal vasodilation with an increase in sodium excretion.
| Descriptor ID |
D015773
|
| MeSH Number(s) |
D12.644.456.345.360.300
|
| Concept/Terms |
Enalaprilat Dihydrate- Enalaprilat Dihydrate
- Dihydrate, Enalaprilat
- 1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline dihydrate
- Enalaprilic Acid
|
Below are MeSH descriptors whose meaning is more general than "Enalaprilat".
Below are MeSH descriptors whose meaning is more specific than "Enalaprilat".
This graph shows the total number of publications written about "Enalaprilat" by people in this website by year, and whether "Enalaprilat" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
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Below are the most recent publications written about "Enalaprilat" by people in Profiles.
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De Mello WC, Monterrubio J. Intracellular and extracellular angiotensin II enhance the L-type calcium current in the failing heart. Hypertension. 2004 Sep; 44(3):360-4.
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De Mello WC. Further studies on the effect of intracellular angiotensins on heart cell communication: on the role of endogenous angiotensin II. Regul Pept. 2003 Aug 15; 115(1):31-6.
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Calhoun DA, Wei CC, Zhu S, Bradley WE, Dell'Italia LJ. Enalaprilat blunts reflexive increases in cardiac interstitial norepinephrine in conscious rats. J Hypertens. 2001 Nov; 19(11):2025-9.
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Calhoun DA, Zhu S. Pretreatment with enalaprilat blunts nicardipine-induced sympathetic activation in spontaneously hypertensive and Wistar-Kyoto rats. J Hypertens. 1999 Apr; 17(4):507-12.