1-Methyl-3-isobutylxanthine
"1-Methyl-3-isobutylxanthine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
| Descriptor ID |
D015056
|
| MeSH Number(s) |
D03.633.100.759.758.824.751.500
|
| Concept/Terms |
1-Methyl-3-isobutylxanthine- 1-Methyl-3-isobutylxanthine
- 1 Methyl 3 isobutylxanthine
- IBMX
- Isobutyltheophylline
- 3-Isobutyl-1-methylxanthine
- 3 Isobutyl 1 methylxanthine
|
Below are MeSH descriptors whose meaning is more general than "1-Methyl-3-isobutylxanthine".
Below are MeSH descriptors whose meaning is more specific than "1-Methyl-3-isobutylxanthine".
This graph shows the total number of publications written about "1-Methyl-3-isobutylxanthine" by people in this website by year, and whether "1-Methyl-3-isobutylxanthine" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "1-Methyl-3-isobutylxanthine" by people in Profiles.
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Cheng S, Jiang X, Yang B, Wen L, Zhao F, Zeng WB, Liu XJ, Dong X, Sun JY, Ming YZ, Zhu H, Rayner S, Tang Q, Fortunato E, Luo MH. Infected T98G glioblastoma cells support human cytomegalovirus reactivation from latency. Virology. 2017 10; 510:205-215.
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Rodriguez G, Ross JA, Nagy ZS, Kirken RA. Forskolin-inducible cAMP pathway negatively regulates T-cell proliferation by uncoupling the interleukin-2 receptor complex. J Biol Chem. 2013 Mar 08; 288(10):7137-46.
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Njie-Mbye YF, Bongmba OY, Onyema CC, Chitnis A, Kulkarni M, Opere CA, LeDay AM, Ohia SE. Effect of hydrogen sulfide on cyclic AMP production in isolated bovine and porcine neural retinae. Neurochem Res. 2010 Mar; 35(3):487-94.
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Karvar S, Yao X, Duman JG, Hybiske K, Liu Y, Forte JG. Intracellular distribution and functional importance of vesicle-associated membrane protein 2 in gastric parietal cells. Gastroenterology. 2002 Jul; 123(1):281-90.
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Ammar DA, Zhou R, Forte JG, Yao X. Syntaxin 3 is required for cAMP-induced acid secretion: streptolysin O-permeabilized gastric gland model. Am J Physiol Gastrointest Liver Physiol. 2002 Jan; 282(1):G23-33.
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Asfaha S, MacNaughton WK, Appleyard CB, Chadee K, Wallace JL. Persistent epithelial dysfunction and bacterial translocation after resolution of intestinal inflammation. Am J Physiol Gastrointest Liver Physiol. 2001 Sep; 281(3):G635-44.
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Gillard ER, Khan AM, Grewal RS, Mouradi B, Wolfsohn SD, Stanley BG. The second messenger cAMP elicits eating by an anatomically specific action in the perifornical hypothalamus. J Neurosci. 1998 Apr 01; 18(7):2646-52.
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Gillard ER, Khan AM, Grewal RS, Mouradi B, Stanley BG. Stimulation of eating by the second messenger cAMP in the perifornical and lateral hypothalamus. Am J Physiol. 1997 Jul; 273(1 Pt 2):R107-12.
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Radziszewski W, Chopra M, Zembowicz A, Gryglewski R, Ignarro LJ, Chaudhuri G. Nitric oxide donors induce extrusion of cyclic GMP from isolated human blood platelets by a mechanism which may be modulated by prostaglandins. Int J Cardiol. 1995 Oct; 51(3):211-20.
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Oyekan AO, Ablordeppey SY. The mechanism(s) of the antiaggregatory effects of cryptolepine: the role of cyclic adenosine monophosphate and cellular Ca2+. Gen Pharmacol. 1993 Mar; 24(2):461-9.