"Taurocholic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.
| Descriptor ID |
D013656
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| MeSH Number(s) |
D02.455.326.146.100.850.875 D02.886.645.600.055.850.800 D04.210.500.105.225.900 D04.210.500.221.430.873
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Taurocholic Acid".
Below are MeSH descriptors whose meaning is more specific than "Taurocholic Acid".
This graph shows the total number of publications written about "Taurocholic Acid" by people in this website by year, and whether "Taurocholic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Taurocholic Acid" by people in Profiles.
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Tian Y, Cai J, Gui W, Nichols RG, Koo I, Zhang J, Anitha M, Patterson AD. Berberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor Activation. Drug Metab Dispos. 2019 02; 47(2):86-93.
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DiMarzio M, Rusconi B, Yennawar NH, Eppinger M, Patterson AD, Dudley EG. Identification of a mouse Lactobacillus johnsonii strain with deconjugase activity against the FXR antagonist T-?-MCA. PLoS One. 2017; 12(9):e0183564.
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Nurunnabi M, Lee SA, Revuri V, Hwang YH, Kang SH, Lee M, Cho S, Cho KJ, Byun Y, Bae YH, Lee DY, Lee YK. Oral delivery of a therapeutic gene encoding glucagon-like peptide 1 to treat high fat diet-induced diabetes. J Control Release. 2017 Dec 28; 268:305-313.
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Khatun Z, Nurunnabi M, Reeck GR, Cho KJ, Lee YK. Oral delivery of taurocholic acid linked heparin-docetaxel conjugates for cancer therapy. J Control Release. 2013 Aug 28; 170(1):74-82.
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Das S, Schteingart CD, Hofmann AF, Reiner DS, Aley SB, Gillin FD. Giardia lamblia: evidence for carrier-mediated uptake and release of conjugated bile acids. Exp Parasitol. 1997 Oct; 87(2):133-41.
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Stark RE, Storrs RW, Levine SE, Yee S, Broido MS. One- and two-dimensional NMR relaxation studies of dynamics and structure in bile salt-phosphatidylcholine mixed micelles. Biochim Biophys Acta. 1986 Aug 21; 860(2):399-410.
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Stark RE, Gosselin GJ, Donovan JM, Carey MC, Roberts MF. Influence of dilution on the physical state of model bile systems: NMR and quasi-elastic light-scattering investigations. Biochemistry. 1985 Sep 24; 24(20):5599-605.