"Substance P" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An eleven-amino acid neurotransmitter that appears in both the central and peripheral nervous systems. It is involved in transmission of PAIN, causes rapid contractions of the gastrointestinal smooth muscle, and modulates inflammatory and immune responses.
| Descriptor ID |
D013373
|
| MeSH Number(s) |
D12.644.276.812.900.866 D12.644.400.800.750 D12.644.456.800.866 D12.776.467.812.900.866 D12.776.631.650.800.750 D23.469.050.375.850.890 D23.529.812.900.866
|
| Concept/Terms |
Substance P- Substance P
- Euler-Gaddum Substance P
- Euler Gaddum Substance P
- Substance P, Euler-Gaddum
- SP(1-11)
|
Below are MeSH descriptors whose meaning is more general than "Substance P".
Below are MeSH descriptors whose meaning is more specific than "Substance P".
This graph shows the total number of publications written about "Substance P" by people in this website by year, and whether "Substance P" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 1999 | 2 | 0 | 2 |
| 2001 | 2 | 0 | 2 |
| 2002 | 0 | 2 | 2 |
| 2003 | 2 | 0 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 1 | 2 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 1 | 2 |
| 2010 | 2 | 1 | 3 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Substance P" by people in Profiles.
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Hernandez S, Cruz ML, Seguinot II, Torres-Reveron A, Appleyard CB. Impact of Psychological Stress on Pain Perception in an Animal Model of Endometriosis. Reprod Sci. 2017 10; 24(10):1371-1381.
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Wang J, Angulo JA. Synergism between methamphetamine and the neuropeptide substance P on the production of nitric oxide in the striatum of mice. Brain Res. 2011 Jan 19; 1369:131-9.
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Hoffmann P, Hoeck K, Deters S, Werner-Martini I, Schmidt WE. Substance P and calcitonin gene related peptide induce TGF-alpha expression in epithelial cells via mast cells and fibroblasts. Regul Pept. 2010 Apr 09; 161(1-3):33-7.
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Chaban VV. Peripheral sensitization of sensory neurons. Ethn Dis. 2010; 20(1 Suppl 1):S1-3-6.
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Zhu J, Xu W, Wang J, Ali SF, Angulo JA. The neurokinin-1 receptor modulates the methamphetamine-induced striatal apoptosis and nitric oxide formation in mice. J Neurochem. 2009 Nov; 111(3):656-68.
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Dehkordi O, Rose JE, Balan KV, Kc P, Millis RM, Jayam-Trouth A. Neuroanatomical relationships of substance P-immunoreactive intrapulmonary C-fibers and nicotinic cholinergic receptors. J Neurosci Res. 2009 May 15; 87(7):1670-8.
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Li J, Micevych P, McDonald J, Rapkin A, Chaban V. Inflammation in the uterus induces phosphorylated extracellular signal-regulated kinase and substance P immunoreactivity in dorsal root ganglia neurons innervating both uterus and colon in rats. J Neurosci Res. 2008 Sep; 86(12):2746-52.
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Bulut K, Felderbauer P, Deters S, Hoeck K, Schmidt-Choudhury A, Schmidt WE, Hoffmann P. Sensory neuropeptides and epithelial cell restitution: the relevance of SP- and CGRP-stimulated mast cells. Int J Colorectal Dis. 2008 May; 23(5):535-41.
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Felderbauer P, Bulut K, Hoeck K, Deters S, Schmidt WE, Hoffmann P. Substance P induces intestinal wound healing via fibroblasts--evidence for a TGF-beta-dependent effect. Int J Colorectal Dis. 2007 Dec; 22(12):1475-80.
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Appleyard CB, Morales M, Santiago C. Chronic inflammation alters the contribution of neurokinin receptor subtypes to epithelial function in rat colon. Dig Dis Sci. 2008 Jan; 53(1):220-8.