"Placental Lactogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A polypeptide hormone of approximately 25 kDa that is produced by the SYNCYTIOTROPHOBLASTS of the PLACENTA, also known as chorionic somatomammotropin. It has both GROWTH HORMONE and PROLACTIN activities on growth, lactation, and luteal steroid production. In women, placental lactogen secretion begins soon after implantation and increases to 1 g or more a day in late pregnancy. Placental lactogen is also an insulin antagonist.
Descriptor ID |
D010928
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MeSH Number(s) |
D06.472.699.649.692 D12.644.548.726.692 D12.776.780.650
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Concept/Terms |
Placental Lactogen- Placental Lactogen
- Lactogen, Placental
- Choriomammotropin
- Lactogen Hormone, Placental
- Mammotropic Hormone, Placental
- Placental Mammotropic Hormone
- Pregnancy-Associated Plasma Protein D
- Pregnancy Associated Plasma Protein D
- Placental Luteotropin
- Luteotropin, Placental
- Somatomammotropin, Chorionic
- Chorionic Somatomammotropin
- Choriomammotrophin
- PAPP-D
Human Placental Lactogen- Human Placental Lactogen
- Placental Lactogen, Human
- HCS (Human Chorionic Somatomammotropin)
- HPL (Human Placental Lactogen)
- Chorionic Somatomammotropin, Human
- Human Chorionic Somatomammotropin
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Below are MeSH descriptors whose meaning is more general than "Placental Lactogen".
Below are MeSH descriptors whose meaning is more specific than "Placental Lactogen".
This graph shows the total number of publications written about "Placental Lactogen" by people in this website by year, and whether "Placental Lactogen" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Placental Lactogen" by people in Profiles.
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Bermea KC, Rodr?guez-Garc?a A, Tsin A, Barrera-Salda?a HA. Somatolactogens and diabetic retinopathy. Growth Horm IGF Res. 2018 Aug; 41:42-47.
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Polgar N, Fogelgren B, Shipley JM, Csiszar K. Lysyl oxidase interacts with hormone placental lactogen and synergistically promotes breast epithelial cell proliferation and migration. J Biol Chem. 2007 Feb 02; 282(5):3262-72.
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Thordarson G, Galosy S, Gudmundsson GO, Newcomer B, Sridaran R, Talamantes F. Interaction of mouse placental lactogens and androgens in regulating progesterone release in cultured mouse luteal cells. Endocrinology. 1997 Aug; 138(8):3236-41.
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Yamaguchi M, Ogren L, Endo H, Thordarson G, Kensinger R, Talamantes F. Epidermal growth factor stimulates mouse placental lactogen I but inhibits mouse placental lactogen II secretion in vitro. Proc Natl Acad Sci U S A. 1992 Dec 01; 89(23):11396-400.
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Yamaguchi M, Ogren L, Endo H, Thordarson G, Bigsby RM, Talamantes F. Production of mouse placental lactogen-I and placental lactogen-II by the same giant cell. Endocrinology. 1992 Oct; 131(4):1595-602.
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Thordarson G, Fielder P, Lee C, Hom YK, Robleto D, Ogren L, Talamantes F. Mammary gland differentiation in hypophysectomized, pregnant mice treated with corticosterone and thyroxine. Biol Reprod. 1992 Oct; 47(4):676-82.
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Fielder PJ, Thordarson G, English A, Rosenfeld RG, Talamantes F. Expression of a lactogen-dependent insulin-like growth factor-binding protein in cultured mouse mammary epithelial cells. Endocrinology. 1992 Jul; 131(1):261-7.
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Yamaguchi M, Endo H, Thordarson G, Ogren L, Talamantes F. Modulation of mouse placental lactogen-I secretion in vitro: effects of progesterone and mouse placental lactogen-II. Endocrinology. 1992 May; 130(5):2897-905.
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Thordarson G, Southard JN, Talamantes F. Purification and characterization of mouse decidual calcyclin: a novel stimulator of mouse placental lactogen-II secretion. Endocrinology. 1991 Sep; 129(3):1257-65.
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Sakbun V, Ali SM, Lee YA, Jara CS, Bryant-Greenwood GD. Immunocytochemical localization and messenger ribonucleic acid concentrations for human placental lactogen in amnion, chorion, decidua, and placenta. Am J Obstet Gynecol. 1990 May; 162(5):1310-7.