"Lethal Dose 50" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.
| Descriptor ID |
D007928
|
| MeSH Number(s) |
E05.940.402 G07.225.500 G07.690.773.875.750 G07.690.936.500.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Lethal Dose 50".
Below are MeSH descriptors whose meaning is more specific than "Lethal Dose 50".
This graph shows the total number of publications written about "Lethal Dose 50" by people in this website by year, and whether "Lethal Dose 50" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 3 | 3 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 4 | 4 |
| 2009 | 0 | 3 | 3 |
| 2010 | 0 | 3 | 3 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 3 | 3 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lethal Dose 50" by people in Profiles.
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Gooch A, Sizochenko N, Rasulev B, Gorb L, Leszczynski J. In vivo toxicity of nitroaromatics: A comprehensive quantitative structure-activity relationship study. Environ Toxicol Chem. 2017 08; 36(8):2227-2233.
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Martinez Gomez DA, Baca S, Walsh EJ. Lethal and sublethal effects of selected PPCPs on the freshwater rotifer, Plationus patulus. Environ Toxicol Chem. 2015 Apr; 34(4):913-22.
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Claudio-Campos K, Hern?ndez-Rivera J, Rivera-Gutierrez J, Ortiz-Rivera I, Carvajal-V?lez A, P?rez-Torres M, Pag?n-Ortiz M, Ospina-Mill?n CA. Biological screening of select Puerto Rican plants for cytotoxic and antitumor activities. P R Health Sci J. 2015 Mar; 34(1):25-30.
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Toropova AP, Toropov AA, Benfenati E, Leszczynska D, Leszczynski J. QSAR model as a random event: A case of rat toxicity. Bioorg Med Chem. 2015 Mar 15; 23(6):1223-30.
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Turabekova MA, Rasulev BF, Dzhakhangirov FN, Toropov AA, Leszczynska D, Leszczynski J. Aconitum and delphinium diterpenoid alkaloids of local anesthetic activity: comparative QSAR analysis based on GA-MLRA/PLS and optimal descriptors approach. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2014; 32(3):213-38.
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Kapono CA, Thapa P, Cabalteja CC, Guendisch D, Collier AC, Bingham JP. Conotoxin truncation as a post-translational modification to increase the pharmacological diversity within the milked venom of Conus magus. Toxicon. 2013 Aug; 70:170-8.
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Shao XM, Xu B, Liang J, Xie XS, Zhu Y, Feldman JL. Nicotine delivery to rats via lung alveolar region-targeted aerosol technology produces blood pharmacokinetics resembling human smoking. Nicotine Tob Res. 2013 Jul; 15(7):1248-58.
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Edwards FL, Yedjou CG, Tchounwou PB. Involvement of oxidative stress in methyl parathion and parathion-induced toxicity and genotoxicity to human liver carcinoma (HepG2) cells. Environ Toxicol. 2013 Jun; 28(6):342-8.
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Puzyn T, Rasulev B, Gajewicz A, Hu X, Dasari TP, Michalkova A, Hwang HM, Toropov A, Leszczynska D, Leszczynski J. Using nano-QSAR to predict the cytotoxicity of metal oxide nanoparticles. Nat Nanotechnol. 2011 Mar; 6(3):175-8.
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Ghosh S, De S, Chen Y, Sutton DC, Ayorinde FO, Dutta SK. Polychlorinated biphenyls (PCB-153) and (PCB-77) absorption in human liver (HepG2) and kidney (HK2) cells in vitro: PCB levels and cell death. Environ Int. 2010 Nov; 36(8):893-900.