Freeze Drying

"Freeze Drying" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Method of tissue preparation in which the tissue specimen is frozen and then dehydrated at low temperature in a high vacuum. This method is also used for dehydrating pharmaceutical and food products.

Descriptor ID	D005612
MeSH Number(s)	E01.370.225.500.620.760.160.260 E01.370.225.750.600.760.160.260 E02.792.156.260 E05.200.500.620.760.160.260 E05.200.750.600.760.160.260 E05.760.156.260
Concept/Terms	Freeze Drying Freeze Drying Drying, Freeze Dryings, Freeze Freeze Dryings Lyophilization Lyophilizations

Below are MeSH descriptors whose meaning is more general than "Freeze Drying".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Diagnosis [E01]
Diagnostic Techniques and Procedures [E01.370]
Clinical Laboratory Techniques [E01.370.225]
Cytological Techniques [E01.370.225.500]
Histocytological Preparation Techniques [E01.370.225.500.620]
Tissue Preservation [E01.370.225.500.620.760]
Cryopreservation [E01.370.225.500.620.760.160]
Freeze Drying [E01.370.225.500.620.760.160.260]
Histological Techniques [E01.370.225.750]
Histocytological Preparation Techniques [E01.370.225.750.600]
Tissue Preservation [E01.370.225.750.600.760]
Cryopreservation [E01.370.225.750.600.760.160]
Freeze Drying [E01.370.225.750.600.760.160.260]
Therapeutics [E02]
Preservation, Biological [E02.792]
Cryopreservation [E02.792.156]
Freeze Drying [E02.792.156.260]
Investigative Techniques [E05]
Clinical Laboratory Techniques [E05.200]
Cytological Techniques [E05.200.500]
Histocytological Preparation Techniques [E05.200.500.620]
Tissue Preservation [E05.200.500.620.760]
Cryopreservation [E05.200.500.620.760.160]
Freeze Drying [E05.200.500.620.760.160.260]
Histological Techniques [E05.200.750]
Histocytological Preparation Techniques [E05.200.750.600]
Tissue Preservation [E05.200.750.600.760]
Cryopreservation [E05.200.750.600.760.160]
Freeze Drying [E05.200.750.600.760.160.260]
Preservation, Biological [E05.760]
Cryopreservation [E05.760.156]
Freeze Drying [E05.760.156.260]

Below are MeSH descriptors whose meaning is related to "Freeze Drying".

Below are MeSH descriptors whose meaning is more specific than "Freeze Drying".

Freeze Drying
Freeze Substitution

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Freeze Drying" by people in this website by year, and whether "Freeze Drying" was a major or minor topic of these publications.

Bar chart showing 21 publications over 15 distinct years, with a maximum of 2 publications in 2000 and 2005 and 2011 and 2013 and 2019 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2000	0	2	2
2003	1	0	1
2005	0	2	2
2007	0	1	1
2008	0	1	1
2009	1	0	1
2011	1	1	2
2013	1	1	2
2014	0	1	1
2019	0	2	2
2021	0	2	2
2022	0	1	1
2023	0	1	1
2024	0	1	1

Below are the most recent publications written about "Freeze Drying" by people in Profiles.

Yu YS, Xu H, AboulFotouh K, Williams G, Suman J, Sahakijpijarn S, Cano C, Warnken ZN, Wu KC, Williams RO, Cui Z. Intranasal delivery of thin-film freeze-dried monoclonal antibodies using a powder nasal spray system. Int J Pharm. 2024 Mar 25; 653:123892.

View in: PubMed
Yu YS, AboulFotouh K, Xu H, Williams G, Suman J, Cano C, Warnken ZN, Wu KC, Williams RO, Cui Z. Feasibility of intranasal delivery of thin-film freeze-dried, mucoadhesive vaccine powders. Int J Pharm. 2023 Jun 10; 640:122990.

View in: PubMed
Wear MP, Hargett AA, Kelly JE, McConnell SA, Crawford CJ, Freedberg DI, Stark RE, Casadevall A. Lyophilization induces physicochemical alterations in cryptococcal exopolysaccharide. Carbohydr Polym. 2022 Sep 01; 291:119547.

View in: PubMed
Preston KB, Wong TAS, To A, Tashiro TE, Lieberman MM, Granados A, Feliciano K, Harrison J, Yalley-Ogunro J, Elyard HA, Donini O, Lehrer AT, Randolph TW. Single-vial filovirus glycoprotein vaccines: Biophysical characteristics and immunogenicity after co-lyophilization with adjuvant. Vaccine. 2021 09 15; 39(39):5650-5657.

View in: PubMed
Shahin H, Vinjamuri BP, Mahmoud AA, Mansour SM, Chougule MB, Chablani L. Formulation and optimization of sildenafil citrate-loaded PLGA large porous microparticles using spray freeze-drying technique: A factorial design and in-vivo pharmacokinetic study. Int J Pharm. 2021 Mar 15; 597:120320.

View in: PubMed
Nerurkar PV, Orias D, Soares N, Kumar M, Nerurkar VR. Momordica charantia (bitter melon) modulates adipose tissue inflammasome gene expression and adipose-gut inflammatory cross talk in high-fat diet (HFD)-fed mice. J Nutr Biochem. 2019 06; 68:16-32.

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Chisholm CF, Kang TJ, Dong M, Lewis K, Namekar M, Lehrer AT, Randolph TW. Thermostable Ebola virus vaccine formulations lyophilized in the presence of aluminum hydroxide. Eur J Pharm Biopharm. 2019 Mar; 136:213-220.

View in: PubMed
Chee G, Rungraeng N, Han JH, Jun S. Electrochemical impedance spectroscopy as an alternative to determine dielectric constant of potatoes at various moisture contents. J Food Sci. 2014 Feb; 79(2):E195-201.

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Bian X, Liang S, John J, Hsiao CH, Wei X, Liang D, Xie H. Development of PLGA-based itraconazole injectable nanospheres for sustained release. Int J Nanomedicine. 2013; 8:4521-31.

View in: PubMed
Youngren SR, Mulik R, Jun B, Hoffmann PR, Morris KR, Chougule MB. Freeze-dried targeted mannosylated selenium-loaded nanoliposomes: development and evaluation. AAPS PharmSciTech. 2013 Sep; 14(3):1012-24.

View in: PubMed

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