"Ethidium" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.
| Descriptor ID |
D004996
|
| MeSH Number(s) |
D03.633.300.633.416
|
| Concept/Terms |
Ethidium Bromide- Ethidium Bromide
- Bromide, Ethidium
- Homidium Bromide
- Bromide, Homidium
|
Below are MeSH descriptors whose meaning is more general than "Ethidium".
Below are MeSH descriptors whose meaning is more specific than "Ethidium".
This graph shows the total number of publications written about "Ethidium" by people in this website by year, and whether "Ethidium" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ethidium" by people in Profiles.
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Singh B, Kisku T, Das S, Mukherjee S, Kundu A, Rath J, Das RS. Refashioning of the drug-properties of fluoroquinolone through the synthesis of a levofloxacin-imidazole cobalt (II) complex and its interaction studies on with DNA and BSA biopolymers, antimicrobial and cytotoxic studies on breast cancer cell lines. Int J Biol Macromol. 2023 Dec 31; 253(Pt 8):127636.
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Ma J, Haldar S, Khan MA, Sharma SD, Merrick WC, Theil EC, Goss DJ. Fe2+ binds iron responsive element-RNA, selectively changing protein-binding affinities and regulating mRNA repression and activation. Proc Natl Acad Sci U S A. 2012 May 29; 109(22):8417-22.
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Langner KM, Kedzierski P, Sokalski WA, Leszczynski J. Physical nature of ethidium and proflavine interactions with nucleic acid bases in the intercalation plane. J Phys Chem B. 2006 May 18; 110(19):9720-7.
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Jorquera RA, Berrios J, Sans J, Vergara C, Benos DJ, Reyes JG. Permeability changes induced by polylysines in rat spermatids. Biol Cell. 2002 Sep; 94(4-5):233-41.
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Miranda M, Ram?rez J, Pe?a A, Coria R. Molecular cloning of the plasma membrane H(+)-ATPase from Kluyveromyces lactis: a single nucleotide substitution in the gene confers ethidium bromide resistance and deficiency in K+ uptake. J Bacteriol. 1995 May; 177(9):2360-7.
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McCarrey JR, Dilworth DD, Sharp RM. Semiquantitative analysis of X-linked gene expression during spermatogenesis in the mouse: ethidium-bromide staining of RT-PCR products. Genet Anal Tech Appl. 1992 Aug; 9(4):117-23.
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Lima MF, Kierszenbaum F. Effects of treatment of trypomastigote forms of Trypanosoma cruzi or host cells with ethidium bromide on cell infection and intracellular fate of the parasite. J Parasitol. 1984 Dec; 70(6):911-7.
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Sunter G, Coutts RH, Buck KW. Negatively supercoiled DNA from plants infected with a single-stranded DNA virus. Biochem Biophys Res Commun. 1984 Feb 14; 118(3):747-52.