Disease Models, Animal

"Disease Models, Animal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Descriptor ID	D004195
MeSH Number(s)	C22.232 E05.598.500 E05.599.395.080
Concept/Terms	Disease Models, Animal Disease Models, Animal Animal Disease Model Animal Disease Models Disease Model, Animal

Below are MeSH descriptors whose meaning is more general than "Disease Models, Animal".

Diseases [C]
Animal Diseases [C22]
Disease Models, Animal [C22.232]
Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Models, Animal [E05.598]
Disease Models, Animal [E05.598.500]
Models, Theoretical [E05.599]
Models, Biological [E05.599.395]
Disease Models, Animal [E05.599.395.080]

Below are MeSH descriptors whose meaning is related to "Disease Models, Animal".

Below are MeSH descriptors whose meaning is more specific than "Disease Models, Animal".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Disease Models, Animal" by people in this website by year, and whether "Disease Models, Animal" was a major or minor topic of these publications.

Bar chart showing 1293 publications over 31 distinct years, with a maximum of 72 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	6	6
1997	2	2	4
1998	2	5	7
1999	0	5	5
2000	3	3	6
2001	1	12	13
2002	5	24	29
2003	4	26	30
2004	1	35	36
2005	4	29	33
2006	6	45	51
2007	2	43	45
2008	4	51	55
2009	4	52	56
2010	6	43	49
2011	8	61	69
2012	9	51	60
2013	1	54	55
2014	6	58	64
2015	6	65	71
2016	8	64	72
2017	5	59	64
2018	5	63	68
2019	8	56	64
2020	4	54	58
2021	0	45	45
2022	0	27	27
2023	2	19	21
2024	19	40	59
2025	1	54	55
2026	0	16	16

Below are the most recent publications written about "Disease Models, Animal" by people in Profiles.

Tsai YT, Tseng YW, Chen YT, Wu SH, Chiu HW, Nguyen HT, Wu CH, Chuang AE, Chen WS, Chen CK. Near-infrared reinforced alginate-tyramine-curcumin gels for alleviation of osteoarthritis in an ACLT murine model. J Mater Chem B. 2026 May 20; 14(19):6089-6108.

View in: PubMed
Figueroa-Gispert MDM, Mel?ndez-V?zquez NM, Espino AM, Godoy-Vitorino F. Intermittent Administration of Helminth-Derived Fh15 Modulates Gut Microbiota and Partially Mitigates Dysbiosis in Early Stages of Severe Experimental Colitis. Int J Mol Sci. 2026 May 02; 27(9).

View in: PubMed
Hon A, Lu M, Shao XM, Demer LL, Tintut Y. Cardiovascular-specific PTH1R activation enhances exercise-induced cardiac remodeling in a mouse model of calcific atherosclerosis. Biochem Biophys Res Commun. 2026 Jul 09; 821:153870.

View in: PubMed
Nakayama Y, Kitaura A, Abdali SA, Nguyen TD, Yoshioka J. Mutations in the Txnip PPXY motifs protect against myocardial infarction despite enhanced protein stability. Am J Physiol Heart Circ Physiol. 2026 Jun 01; 330(6):H1732-H1748.

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Armina-Rodriguez A, Dorta-Estremera SM, Mendez LB, Espino AM. Protection of mice against septic shock induced by lethal intraperitoneal dose of LPS by a recombinant Fasciola hepatica fatty acid binding protein. Microbiol Spectr. 2026 Apr 07; 14(4):e0275625.

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Zhou J, Yang Y, Liu S, Chen J, Liao H, Liang W, Zhang Z, Wang Y, Liu Y, Zhang H, Jiang H, Lin W, Qu J, Barger SW, Wu S. Microglial serine racemase knockout alleviates Alzheimer-like neuropathology and behavioral deficit via lactylation-mediated anti-inflammation. Commun Biol. 2026 Feb 25; 9(1).

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Li Y, Al Rimon R, Wang F, Li H, Epelman S, Tallquist MD, Westover L, Oudit GY, Kassiri Z. Temporal inhibition of ADAM17 in fibroblasts reduces stiffness and promotes vascularization following myocardial infarction. Cardiovasc Res. 2026 Feb 24; 122(1):112-131.

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Zhao P, El Fadel O, Le A, Mangleburg CG, Dhindsa J, Wu T, Zhao J, Huang M, Amoh B, Marella AS, Li Y, Seyfried NT, Levey AI, Liu Z, Al-Ramahi I, Botas J, Shulman JM. Systems genetic dissection of brain gene expression reveals excitotoxic mechanisms of Alzheimer's disease. Mol Psychiatry. 2026 Jun; 31(6):3462-3481.

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Elia A, Parodi-Rullan R, Vazquez-Torres R, Carey A, Zhao H, Javadov S, Fossati S. Amyloid ? Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease. Adv Sci (Weinh). 2026 Apr; 13(20):e11924.

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Tanji Y, Shimada S, Kato M, Akiyama Y, Hatano M, Tsukihara S, Igarashi Y, Kodera K, Okazaki K, Yasukawa K, Umemura K, Kamachi A, Nara A, Yamane M, Ishikawa Y, Mochizuki E, Mochida Y, Ikegami T, Ban D, Uchida S, Tanaka S. Cytokine mRNA-based therapy alleviates dendritic cell and T cell paucity to eliminate aggressive pancreatic cancer in preclinical mouse models. EBioMedicine. 2026 Mar; 125:106137.

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