"Microbial Collagenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.
Descriptor ID |
D003012
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MeSH Number(s) |
D08.811.277.656.300.480.205.500 D08.811.277.656.675.374.205.500
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Concept/Terms |
Microbial Collagenase- Microbial Collagenase
- Clostridium histolyticum Collagenase
- Collagenase, Clostridium histolyticum
- Nucleolysin
- Collagenase, Microbial
- Collalysine
- Clostridiopeptidase A
- Collagenase Clostridium histolyticum
- Clostridium histolyticum, Collagenase
- histolyticum, Collagenase Clostridium
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Below are MeSH descriptors whose meaning is more general than "Microbial Collagenase".
Below are MeSH descriptors whose meaning is more specific than "Microbial Collagenase".
This graph shows the total number of publications written about "Microbial Collagenase" by people in this website by year, and whether "Microbial Collagenase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Microbial Collagenase" by people in Profiles.
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Lekic T, Klebe D, Flores J, Peters R, Rolland WB, Tang J, Zhang JH. Remote Ischemic Postconditioning (RIPC) After GMH in Rodents. Acta Neurochir Suppl. 2016; 121:63-7.
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Koay ES, Bryant-Greenwood GD, Yamamoto SY, Greenwood FC. The human fetal membranes: a target tissue for relaxin. J Clin Endocrinol Metab. 1986 Mar; 62(3):513-21.
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Too CK, Kong JK, Greenwood FC, Bryant-Greenwood GD. The effect of oestrogen and relaxin on uterine and cervical enzymes: collagenase, proteoglycanase and beta-glycuronidase. Acta Endocrinol (Copenh). 1986 Mar; 111(3):394-403.
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Beach RL, Rao JS, Festoff BW, Reyes ET, Yanagihara R, Gajdusek DC. Collagenase activity in skin fibroblasts of patients with amyotrophic lateral sclerosis. J Neurol Sci. 1986 Jan; 72(1):49-60.
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Too CK, Bryant-Greenwood GD, Greenwood FC. Relaxin increases the release of plasminogen activator, collagenase, and proteoglycanase from rat granulosa cells in vitro. Endocrinology. 1984 Sep; 115(3):1043-50.
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Koay ES, Too CK, Greenwood FC, Bryant-Greenwood GD. Relaxin stimulates collagenase and plasminogen activator secretion by dispersed human amnion and chorion cells in vitro. J Clin Endocrinol Metab. 1983 Jun; 56(6):1332-4.
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Arinze IJ, Rowley DL. Gluconeogenesis by isolated guinea-pig liver parenchymal cells. Biochem J. 1975 Nov; 152(2):393-9.