"Choline Deficiency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A condition produced by a deficiency of CHOLINE in animals. Choline is known as a lipotropic agent because it has been shown to promote the transport of excess fat from the liver under certain conditions in laboratory animals. Combined deficiency of choline (included in the B vitamin complex) and all other methyl group donors causes liver cirrhosis in some animals. Unlike compounds normally considered as vitamins, choline does not serve as a cofactor in enzymatic reactions. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)
| Descriptor ID |
D002796
|
| MeSH Number(s) |
C18.654.521.500.133.699.160
|
| Concept/Terms |
Choline Deficiency- Choline Deficiency
- Deficiency, Choline
- Choline Deficiencies
- Deficiencies, Choline
|
Below are MeSH descriptors whose meaning is more general than "Choline Deficiency".
Below are MeSH descriptors whose meaning is more specific than "Choline Deficiency".
This graph shows the total number of publications written about "Choline Deficiency" by people in this website by year, and whether "Choline Deficiency" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Choline Deficiency" by people in Profiles.
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Yamada A, Watanabe A, Nara A, Ishimaru N, Maeda K, Ido Y, Kotake K, Asano M, Shinohara Y, Yamamoto T. Longitudinal Analysis of Mitochondrial Function in a Choline-Deficient L-Amino Acid-Defined High-Fat Diet-Induced Metabolic Dysfunction-Associated Steatohepatitis Mouse Model. Int J Mol Sci. 2024 Jun 04; 25(11).
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Wilson DM, Di Gialleonardo V, Wang ZJ, Carroll V, Von Morze C, Taylor A, Sai V, VanCriekinge M, Bok R, Ohliger MA, Keshari KR. Hyperpolarized 13C Spectroscopic Evaluation of Oxidative Stress in a Rodent Model of Steatohepatitis. Sci Rep. 2017 04 20; 7:46014.
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Gyamfi MA, Tanaka Y, He L, Klaassen CD, Wan YJ. Hepatic effects of a methionine-choline-deficient diet in hepatocyte RXRalpha-null mice. Toxicol Appl Pharmacol. 2009 Jan 15; 234(2):166-78.
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Gyamfi MA, Damjanov I, French S, Wan YJ. The pathogenesis of ethanol versus methionine and choline deficient diet-induced liver injury. Biochem Pharmacol. 2008 Feb 15; 75(4):981-95.