Choline

"Choline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.

Descriptor ID	D002794
MeSH Number(s)	D02.033.100.291.211 D02.092.063.291.211 D02.092.877.883.333 D02.675.276.232
Concept/Terms	Choline Choline 2-Hydroxy-N,N,N-trimethylethanaminium Choline Citrate Choline Citrate Citrate, Choline Choline O-Sulfate Choline O-Sulfate Choline O Sulfate O-Sulfate, Choline Choline Hydroxide Choline Hydroxide Hydroxide, Choline Bursine Bursine Vidine Fagine Choline Bitartrate Choline Bitartrate Bitartrate, Choline Choline Chloride Choline Chloride Chloride, Choline

Below are MeSH descriptors whose meaning is more general than "Choline".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Alcohols [D02.033]
Amino Alcohols [D02.033.100]
Ethanolamines [D02.033.100.291]
Choline [D02.033.100.291.211]
Amines [D02.092]
Amino Alcohols [D02.092.063]
Ethanolamines [D02.092.063.291]
Choline [D02.092.063.291.211]
Quaternary Ammonium Compounds [D02.092.877]
Trimethyl Ammonium Compounds [D02.092.877.883]
Choline [D02.092.877.883.333]
Onium Compounds [D02.675]
Quaternary Ammonium Compounds [D02.675.276]
Choline [D02.675.276.232]

Below are MeSH descriptors whose meaning is related to "Choline".

Below are MeSH descriptors whose meaning is more specific than "Choline".

Choline
Platelet Activating Factor

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Choline" by people in this website by year, and whether "Choline" was a major or minor topic of these publications.

Bar chart showing 48 publications over 22 distinct years, with a maximum of 5 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	1	1	2
2005	1	1	2
2006	1	1	2
2007	3	0	3
2008	3	2	5
2009	1	1	2
2010	2	1	3
2011	1	0	1
2012	2	0	2
2013	1	0	1
2014	2	1	3
2015	0	2	2
2016	2	2	4
2017	2	0	2
2018	1	0	1
2019	2	0	2
2020	2	0	2
2021	0	1	1
2022	2	2	4
2024	0	2	2
2025	0	1	1
2026	1	0	1

Below are the most recent publications written about "Choline" by people in Profiles.

Arif M, Basu A, Zuo BLG, Zuo MXG, O'Brien KJ, Pommerolle L, Caro-Rivera LM, De Jesus-Rojas W, Ramos-Benitez MJ, Behan M, Introne WJ, Frost G, Moaddel R, Gahl WA, Malicdan MCV, Gochuico BR, Cinar R. Choline and CCL22 Are Prognostic Blood Biomarkers for Hermansky-Pudlak Syndrome Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2026 Jan 01; 74(1):80-93.

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Nemat RA, Chaya T, Atheby AC, Lawal HO. Altered Vesicular Acetylcholine Transporter Expression Regulates Acetylcholine Abundance in the Brain of Drosophila melanogaster. J Neurochem. 2025 Jun; 169(6):e70109.

View in: PubMed
Yamada A, Watanabe A, Nara A, Ishimaru N, Maeda K, Ido Y, Kotake K, Asano M, Shinohara Y, Yamamoto T. Longitudinal Analysis of Mitochondrial Function in a Choline-Deficient L-Amino Acid-Defined High-Fat Diet-Induced Metabolic Dysfunction-Associated Steatohepatitis Mouse Model. Int J Mol Sci. 2024 Jun 04; 25(11).

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Sawicki CM, Pacheco LS, Rivas-Tumanyan S, Cao Z, Haslam DE, Liang L, Tucker KL, Joshipura K, Bhupathiraju SN. Association of Gut Microbiota-Related Metabolites and Type 2 Diabetes in Two Puerto Rican Cohorts. Nutrients. 2024 Mar 27; 16(7).

View in: PubMed
Andrews JR, Ahmed ME, Sharma V, Britton C, Stish B, Phillips R, Kendi AT, Joshi VB, Sood A, Tollefson MK, Boorjian SA, Karnes RJ, Kwon ED. Metastasis-directed Therapy Without Androgen Deprivation Therapy in Solitary Oligorecurrent Prostate Cancer. J Urol. 2022 12; 208(6):1240-1249.

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Huda MN, Deaguero IG, Borrego EA, Kumar R, Islam T, Afrin H, Varela-Ramirez A, Aguilera RJ, Tanner EEL, Nurunnabi M. Ionic liquid-mediated delivery of a BCL-2 inhibitor for topical treatment of skin melanoma. J Control Release. 2022 09; 349:783-795.

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Felipe A, Lovenduski CA, Baker JL, Lindberg GE. Long-ranged heterogeneous structure in aqueous solutions of the deep eutectic solvent choline and geranate at the liquid-vapor interface. Phys Chem Chem Phys. 2022 Jun 08; 24(22):13720-13729.

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Fraenza CC, Elgammal RA, Garaga MN, Bhattacharyya S, Zawodzinski TA, Greenbaum SG. Dynamics of Glyceline and Interactions of Constituents: A Multitechnique NMR Study. J Phys Chem B. 2022 02 03; 126(4):890-905.

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Li J, Li Y, Ivey KL, Wang DD, Wilkinson JE, Franke A, Lee KH, Chan A, Huttenhower C, Hu FB, Rimm EB, Sun Q. Interplay between diet and gut microbiome, and circulating concentrations of trimethylamine N-oxide: findings from a longitudinal cohort of US men. Gut. 2022 04; 71(4):724-733.

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Bardsley TA, Evans CL, Greene JR, Audet R, Harrison MJ, Zimmerman M, Nieto NC, Del Sesto RE, Koppisch AT, Kellar RS. Integration of choline geranate into electrospun protein scaffolds affords antimicrobial activity to biomaterials used for cutaneous wound healing. J Biomed Mater Res B Appl Biomater. 2021 09; 109(9):1271-1282.

View in: PubMed

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