RCMI Coordinating Center (RCMI CC) Header Logo

Connection

Khosrow Kashfi to Nitric Oxide

This is a "connection" page, showing publications Khosrow Kashfi has written about Nitric Oxide.
Connection Strength

11.780
  1. O'Connor JL, Fountos DM, Firouzan B, Azizi F, Ghasemi R, Kashfi K. The role of gasotransmitters in Parkinson's disease: Interplay of nitric oxide, carbon monoxide, and hydrogen sulfide. Neurotherapeutics. 2025 Oct; 22(6):e00710.
    View in: PubMed
    Score: 0.753
  2. Ghasemi A, Jeddi S, Kashfi K. Brain glucose metabolism: Role of nitric oxide. Biochem Pharmacol. 2025 02; 232:116728.
    View in: PubMed
    Score: 0.723
  3. Dos Reis RA, Sarkar I, Rodrigues MG, Matson JB, Seabra AB, Kashfi K. NO- and H2S- releasing nanomaterials: A crosstalk signaling pathway in cancer. Nitric Oxide. 2024 Oct 01; 151:17-30.
    View in: PubMed
    Score: 0.707
  4. Kashfi K. Dedication to Dr. Larry K. Keefer at the Sixth International Workshop on Nitric Oxide in Cancer and Beyond. Crit Rev Oncog. 2023; 28(1):xi-xviii.
    View in: PubMed
    Score: 0.631
  5. Kashfi K. Fifty Years of Diazeniumdiolate Research: A Tribute to Dr. Larry K. Keefer. Crit Rev Oncog. 2023; 28(1):47-55.
    View in: PubMed
    Score: 0.631
  6. Kashfi K, Kannikal J, Nath N. Macrophage Reprogramming and Cancer Therapeutics: Role of iNOS-Derived NO. Cells. 2021 11 16; 10(11).
    View in: PubMed
    Score: 0.583
  7. Kashfi K. Nitric oxide in cancer and beyond. Biochem Pharmacol. 2020 06; 176:114006.
    View in: PubMed
    Score: 0.524
  8. Dillon KM, Carrazzone RJ, Matson JB, Kashfi K. The evolving landscape for cellular nitric oxide and hydrogen sulfide delivery systems: A new era of customized medications. Biochem Pharmacol. 2020 06; 176:113931.
    View in: PubMed
    Score: 0.521
  9. Nath N, Kashfi K. Tumor associated macrophages and 'NO'. Biochem Pharmacol. 2020 06; 176:113899.
    View in: PubMed
    Score: 0.518
  10. Gheibi S, Samsonov AP, Gheibi S, Vazquez AB, Kashfi K. Regulation of carbohydrate metabolism by nitric oxide and hydrogen sulfide: Implications in diabetes. Biochem Pharmacol. 2020 06; 176:113819.
    View in: PubMed
    Score: 0.514
  11. Bahadoran Z, Mirmiran P, Ghasemi A, Kashfi K. Type 2 Diabetes and Cancer: The Nitric Oxide Connection. Crit Rev Oncog. 2019; 24(3):235-242.
    View in: PubMed
    Score: 0.478
  12. Kashfi K. Utility Of Nitric Oxide And Hydrogen Sulfide-Releasing Chimeras As Anticancer Agents. Redox Biol. 2015 08; 5:420.
    View in: PubMed
    Score: 0.388
  13. Kodela R, Chattopadhyay M, Vel?zquez-Mart?nez CA, Kashfi K. NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid has enhanced chemo-preventive properties compared to aspirin, is gastrointestinal safe with all the classic therapeutic indications. Biochem Pharmacol. 2015 Dec 15; 98(4):564-72.
    View in: PubMed
    Score: 0.381
  14. Kashfi K, Chattopadhyay M, Kodela R. NOSH-sulindac (AVT-18A) is a novel nitric oxide- and hydrogen sulfide-releasing hybrid that is gastrointestinal safe and has potent anti-inflammatory, analgesic, antipyretic, anti-platelet, and anti-cancer properties. Redox Biol. 2015 Dec; 6:287-296.
    View in: PubMed
    Score: 0.378
  15. Vannini F, MacKessack-Leitch AC, Eschbach EK, Chattopadhyay M, Kodela R, Kashfi K. Synthesis and anti-cancer potential of the positional isomers of NOSH-aspirin (NBS-1120) a dual nitric oxide and hydrogen sulfide releasing hybrid. Bioorg Med Chem Lett. 2015 Oct 15; 25(20):4677-82.
    View in: PubMed
    Score: 0.378
  16. Chattopadhyay M, Kodela R, Olson KR, Kashfi K. NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid is a potent inhibitor of colon cancer cell growth in vitro and in a xenograft mouse model. Biochem Biophys Res Commun. 2012 Mar 16; 419(3):523-8.
    View in: PubMed
    Score: 0.297
  17. Nath N, Chattopadhyay M, Pospishil L, Cieciura LZ, Goswami S, Kodela R, Saavedra JE, Keefer LK, Kashfi K. JS-K, a nitric oxide-releasing prodrug, modulates ?-catenin/TCF signaling in leukemic Jurkat cells: evidence of an S-nitrosylated mechanism. Biochem Pharmacol. 2010 Dec 01; 80(11):1641-9.
    View in: PubMed
    Score: 0.268
  18. Kashfi K, Rigas B. The mechanism of action of nitric oxide-donating aspirin. Biochem Biophys Res Commun. 2007 Jul 13; 358(4):1096-101.
    View in: PubMed
    Score: 0.213
  19. Farahani A, Farahani A, Kashfi K, Ghasemi A. Inhibition of hepatic gluconeogenesis in type 2 diabetes by metformin: complementary role of nitric oxide. Med Gas Res. 2025 Dec 01; 15(4):507-519.
    View in: PubMed
    Score: 0.185
  20. Chattopadhyay M, Nath N, Kodela R, Metkar S, Soyemi SA, Kashfi K. NOSH-aspirin (NBS-1120) inhibits estrogen receptor-negative breast cancer in?vitro and in?vivo by modulating redox-sensitive signaling pathways. J Pharmacol Exp Ther. 2025 Jan; 392(1):100019.
    View in: PubMed
    Score: 0.180
  21. Bahadoran Z, Mirmiran P, Hosseinpanah F, Kashfi K, Ghasemi A. Nitric oxide-based treatments improve wound healing associated with diabetes mellitus. Med Gas Res. 2025 Mar 01; 15(1):23-35.
    View in: PubMed
    Score: 0.176
  22. Oza PP, Kashfi K. The Triple Crown: NO, CO, and H2S in cancer cell biology. Pharmacol Ther. 2023 09; 249:108502.
    View in: PubMed
    Score: 0.164
  23. Bahadoran Z, Mirmiran P, Kashfi K, Ghasemi A. Vascular nitric oxide resistance in type 2 diabetes. Cell Death Dis. 2023 07 11; 14(7):410.
    View in: PubMed
    Score: 0.163
  24. Ranjbar T, Oza PP, Kashfi K. The Renin-Angiotensin-Aldosterone System, Nitric Oxide, and Hydrogen Sulfide at the Crossroads of Hypertension and COVID-19: Racial Disparities and Outcomes. Int J Mol Sci. 2022 Nov 11; 23(22).
    View in: PubMed
    Score: 0.156
  25. Oza PP, Kashfi K. Utility of NO and H2S donating platforms in managing COVID-19: Rationale and promise. Nitric Oxide. 2022 11 01; 128:72-102.
    View in: PubMed
    Score: 0.154
  26. Jeddi S, Yousefzadeh N, Kashfi K, Ghasemi A. Role of nitric oxide in type 1 diabetes-induced osteoporosis. Biochem Pharmacol. 2022 03; 197:114888.
    View in: PubMed
    Score: 0.147
  27. Bahadoran Z, Mirmiran P, Kashfi K, Ghasemi A. Hyperuricemia-induced endothelial insulin resistance: the nitric oxide connection. Pflugers Arch. 2022 01; 474(1):83-98.
    View in: PubMed
    Score: 0.143
  28. Antoniou C, Xenofontos R, Chatzimichail G, Christou A, Kashfi K, Fotopoulos V. Exploring the Potential of Nitric Oxide and Hydrogen Sulfide (NOSH)-Releasing Synthetic Compounds as Novel Priming Agents against Drought Stress in Medicago sativa Plants. Biomolecules. 2020 01 10; 10(1).
    View in: PubMed
    Score: 0.128
  29. Kashfi K. The role of hydrogen sulfide in health and disease. Biochem Pharmacol. 2018 03; 149:1-4.
    View in: PubMed
    Score: 0.113
  30. Kashfi K. The dichotomous role of H2S in cancer cell biology? D?j? vu all over again. Biochem Pharmacol. 2018 03; 149:205-223.
    View in: PubMed
    Score: 0.112
  31. Gheibi S, Jeddi S, Kashfi K, Ghasemi A. Regulation of vascular tone homeostasis by NO and H2S: Implications in hypertension. Biochem Pharmacol. 2018 03; 149:42-59.
    View in: PubMed
    Score: 0.112
  32. Vannini F, Chattopadhyay M, Kodela R, Rao PPN, Kashfi K. Positional isomerism markedly affects the growth inhibition of colon cancer cells by NOSH-aspirin: COX inhibition and modeling. Redox Biol. 2015 Dec; 6:318-325.
    View in: PubMed
    Score: 0.095
  33. Nath N, Liu X, Jacobs L, Kashfi K. Flurbiprofen benzyl nitrate (NBS-242) inhibits the growth of A-431 human epidermoid carcinoma cells and targets ?-catenin. Drug Des Devel Ther. 2013; 7:389-96.
    View in: PubMed
    Score: 0.081
  34. Jain S, Tran S, El Gendy MA, Kashfi K, Jurasz P, Vel?zquez-Mart?nez CA. Nitric oxide release is not required to decrease the ulcerogenic profile of nonsteroidal anti-inflammatory drugs. J Med Chem. 2012 Jan 26; 55(2):688-96.
    View in: PubMed
    Score: 0.074
  35. Chattopadhyay M, Goswami S, Rodes DB, Kodela R, Velazquez CA, Boring D, Crowell JA, Kashfi K. NO-releasing NSAIDs suppress NF-?B signaling in vitro and in vivo through S-nitrosylation. Cancer Lett. 2010 Dec 08; 298(2):204-11.
    View in: PubMed
    Score: 0.067
  36. Gao J, Kashfi K, Liu X, Rigas B. NO-donating aspirin induces phase II enzymes in vitro and in vivo. Carcinogenesis. 2006 Apr; 27(4):803-10.
    View in: PubMed
    Score: 0.048
  37. Jeddi S, Kashfi K, Ghasemi A. The potential role of nitrate, a nitric oxide donor, in the prevention and treatment of diabetic osteoporosis. Front Endocrinol (Lausanne). 2025; 16:1480838.
    View in: PubMed
    Score: 0.047
  38. Kashfi K, Borgo S, Williams JL, Chen J, Gao J, Glekas A, Benedini F, Del Soldato P, Rigas B. Positional isomerism markedly affects the growth inhibition of colon cancer cells by nitric oxide-donating aspirin in vitro and in vivo. J Pharmacol Exp Ther. 2005 Mar; 312(3):978-88.
    View in: PubMed
    Score: 0.045
  39. Williams JL, Kashfi K, Ouyang N, del Soldato P, Kopelovich L, Rigas B. NO-donating aspirin inhibits intestinal carcinogenesis in Min (APC(Min/+)) mice. Biochem Biophys Res Commun. 2004 Jan 16; 313(3):784-8.
    View in: PubMed
    Score: 0.042
  40. Yassaghi Y, Jeddi S, Yousefzadeh N, Kashfi K, Ghasemi A. Long-term inorganic nitrate administration protects against myocardial ischemia-reperfusion injury in female rats. BMC Cardiovasc Disord. 2023 08 21; 23(1):411.
    View in: PubMed
    Score: 0.041
  41. Yousefzadeh N, Jeddi S, Zarkesh M, Kashfi K, Ghasemi A. Altered sialin mRNA gene expression in type 2 diabetic male Wistar rats: implications for nitric oxide deficiency. Sci Rep. 2023 03 10; 13(1):4013.
    View in: PubMed
    Score: 0.040
  42. Yousefzadeh N, Jeddi S, Afzali H, Kashfi K, Ghasemi A. Chronic nitrate administration increases the expression the genes involved in the browning of white adipose tissue in female rats. Cell Biochem Funct. 2022 Oct; 40(7):750-759.
    View in: PubMed
    Score: 0.039
  43. Jeddi S, Gheibi S, Afzali H, Carlstr?m M, Kashfi K, Ghasemi A. Hydrogen sulfide potentiates the protective effects of nitrite against myocardial ischemia-reperfusion injury in type 2 diabetic rats. Nitric Oxide. 2022 07 01; 124:15-23.
    View in: PubMed
    Score: 0.038
  44. Bahadoran Z, Mirmiran P, Kashfi K, Ghasemi A. Carbon monoxide and ?-cell function: Implications for type 2 diabetes mellitus. Biochem Pharmacol. 2022 07; 201:115048.
    View in: PubMed
    Score: 0.038
  45. Kaza CS, Kashfi K, Rigas B. Colon cancer prevention with NO-releasing NSAIDs. Prostaglandins Other Lipid Mediat. 2002 Feb; 67(2):107-20.
    View in: PubMed
    Score: 0.037
  46. Baidoo JNE, Mukherjee S, Kashfi K, Banerjee P. A New Perspective on Cancer Therapy: Changing the Treaded Path? Int J Mol Sci. 2021 Sep 11; 22(18).
    View in: PubMed
    Score: 0.036
  47. Bahadoran Z, Mirmiran P, Kashfi K, Ghasemi A. Lost-in-Translation of Metabolic Effects of Inorganic Nitrate in Type 2 Diabetes: Is Ascorbic Acid the Answer? Int J Mol Sci. 2021 Apr 29; 22(9).
    View in: PubMed
    Score: 0.035
  48. Shokri M, Jeddi S, Faridnouri H, Khorasani V, Kashfi K, Ghasemi A. Effect of Nitrate on Gene and Protein Expression of Nitric Oxide Synthase Enzymes in Insulin-Sensitive Tissues of Type 2 Diabetic Male Rats Endocr Metab Immune Disord Drug Targets. 2021; 21(12):2220-2230.
    View in: PubMed
    Score: 0.034
  49. Bahadoran Z, Mirmiran P, Kashfi K, Ghasemi A. Endogenous flux of nitric oxide: Citrulline is preferred to Arginine. Acta Physiol (Oxf). 2021 03; 231(3):e13572.
    View in: PubMed
    Score: 0.034
  50. Jeddi S, Gheibi S, Kashfi K, Carlstr?m M, Ghasemi A. Protective effect of intermediate doses of hydrogen sulfide against myocardial ischemia-reperfusion injury in obese type 2 diabetic rats. Life Sci. 2020 Sep 01; 256:117855.
    View in: PubMed
    Score: 0.033
  51. Jeddi S, Gheibi S, Kashfi K, Carlstr?m M, Ghasemi A. Dose-Dependent Effects of Long-Term Administration of Hydrogen Sulfide on Myocardial Ischemia-Reperfusion Injury in Male Wistar Rats: Modulation of RKIP, NF-?B, and Oxidative Stress. Int J Mol Sci. 2020 Feb 19; 21(4).
    View in: PubMed
    Score: 0.032
  52. Bakhtiarzadeh F, Siavoshi F, Gheibi S, Kashfi K, Samadi R, Jeddi S, Ghasemi A. Effects of long-term oral nitrate administration on adiposity in normal adult female rats. Life Sci. 2018 Oct 01; 210:76-85.
    View in: PubMed
    Score: 0.029
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

For technical support please contact support