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Omid A. Khorram, MD, PhD

TitleProfessor
Faculty RankProfessor
InstitutionCharles R. Drew University of Medicine and Science
DepartmentInternal Medicine
Address1731 E. 120th Street
1731 E. 120th Street
Los Angeles CA 90059
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    Collapse Research 
    Collapse research activities and funding
    R03HD041409     (KHORRAM, OMID A.)Apr 1, 2002 - Mar 31, 2005
    NIH
    Human Endometrial Nitric Oxide: Regulation and Function
    Role: Principal Investigator

    R03HD054920     (KHORRAM, OMID A.)Sep 14, 2007 - Aug 31, 2009
    NIH
    Glucocorticoids and Programming of the Hypertensive Vascular Phenotype
    Role: Principal Investigator

    R21HD088868     (KHORRAM, OMID A.)Aug 10, 2017 - Jul 31, 2020
    NIH
    Role of miR29c and miR200c in leiomyoma pathogenesis
    Role: Principal Investigator

    R01HD100529     (KHORRAM, OMID A.)Sep 8, 2020 - Jun 30, 2024
    NIH
    Mechanism of Long Non-coding RNAs Action in leiomyoma
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chuang TD, Rehan A, Khorram O. Functional role of the long noncoding RNA X-inactive specific transcript in leiomyoma pathogenesis. Fertil Steril. 2021 Jan; 115(1):238-247. PMID: 33070965.
      Citations:    Fields:    
    2. Chuang TD, Ansari A, Yu C, Sakurai R, Harb A, Liu J, Khorram O, Rehan VK. Mechanism underlying increased cardiac extracellular matrix deposition in perinatal nicotine-exposed offspring. Am J Physiol Heart Circ Physiol. 2020 09 01; 319(3):H651-H660. PMID: 32795172.
      Citations:    Fields:    Translation:AnimalsCells
    3. Chuang TD, Rehan A, Khorram O. Tranilast induces MiR-200c expression through blockade of RelA/p65 activity in leiomyoma smooth muscle cells. Fertil Steril. 2020 06; 113(6):1308-1318. PMID: 32199621.
      Citations:    Fields:    
    4. Chuang TD, Khorram O. Cross-talk between miR-29c and transforming growth factor-ß3 is mediated by an epigenetic mechanism in leiomyoma. Fertil Steril. 2019 12; 112(6):1180-1189. PMID: 31843095.
      Citations:    Fields:    Translation:HumansCells
    5. Chuang TD, Sakurai R, Gong M, Khorram O, Rehan VK. Role of miR-29 in mediating offspring lung phenotype in a rodent model of intrauterine growth restriction. . 2018 11 01; 315(5):R1017-R1026. PMID: 30088984.
      Citations:    
    6. Chuang TD, Xie Y, Yan W, Khorram O. Next-generation sequencing reveals differentially expressed small noncoding RNAs in uterine leiomyoma. Fertil Steril. 2018 05; 109(5):919-929. PMID: 29778390.
      Citations: 3     Fields:    Translation:Humans
    7. Chuang TD, Khorram O. Regulation of Cell Cycle Regulatory Proteins by MicroRNAs in Uterine Leiomyoma. Reprod Sci. 2019 02; 26(2):250-258. PMID: 29642801.
      Citations: 6     Fields:    Translation:Humans
    8. Chuang TD, Khorram O. Glucocorticoids regulate MiR-29c levels in vascular smooth muscle cells through transcriptional and epigenetic mechanisms. Life Sci. 2017 Oct 01; 186:87-91. PMID: 28801263.
      Citations: 3     Fields:    Translation:AnimalsCells
    9. Chuang TD, Khorram O. Expression Profiling of lncRNAs, miRNAs, and mRNAs and Their Differential Expression in Leiomyoma Using Next-Generation RNA Sequencing. Reprod Sci. 2018 02; 25(2):246-255. PMID: 28587571.
      Citations: 6     Fields:    Translation:Humans
    10. Chuang TD, Khorram O. Tranilast Inhibits Genes Functionally Involved in Cell Proliferation, Fibrosis, and Epigenetic Regulation and Epigenetically Induces miR-29c Expression in Leiomyoma Cells. Reprod Sci. 2017 09; 24(9):1253-1263. PMID: 28114878.
      Citations: 8     Fields:    Translation:HumansCells
    11. Chuang TD, Khorram O. Mechanisms underlying aberrant expression of miR-29c in uterine leiomyoma. Fertil Steril. 2016 Jan; 105(1):236-45.e1. PMID: 26453978.
      Citations: 8     Fields:    Translation:HumansCells
    12. Chuang TD, Pearce WJ, Khorram O. miR-29c induction contributes to downregulation of vascular extracellular matrix proteins by glucocorticoids. . 2015 Jul 15; 309(2):C117-25. PMID: 26017148.
      Citations:    
    13. Khorram O, Keen-Rinehart E, Chuang TD, Ross MG, Desai M. Maternal undernutrition induces premature reproductive senescence in adult female rat offspring. Fertil Steril. 2015 Jan; 103(1):291-8.e2. PMID: 25439841.
      Citations: 12     Fields:    Translation:Animals
    14. Chuang TD, Ho M, Khorram O. The regulatory function of miR-200c on inflammatory and cell-cycle associated genes in SK-LMS-1, a leiomyosarcoma cell line. Reprod Sci. 2015 May; 22(5):563-71. PMID: 25305131.
      Citations: 7     Fields:    Translation:HumansCells
    15. Paek DS, Sakurai R, Saraswat A, Li Y, Khorram O, Torday JS, Rehan VK. Metyrapone alleviates deleterious effects of maternal food restriction on lung development and growth of rat offspring. Reprod Sci. 2015 Feb; 22(2):207-22. PMID: 24916330.
      Citations: 5     Fields:    Translation:AnimalsCells
    16. Huang G, Basaria S, Travison TG, Ho MH, Davda M, Mazer NA, Miciek R, Knapp PE, Zhang A, Collins L, Ursino M, Appleman E, Dzekov C, Stroh H, Ouellette M, Rundell T, Baby M, Bhatia NN, Khorram O, Friedman T, Storer TW, Bhasin S. Testosterone dose-response relationships in hysterectomized women with or without oophorectomy: effects on sexual function, body composition, muscle performance and physical function in a randomized trial. Menopause. 2014 Jun; 21(6):612-23. PMID: 24281237.
      Citations: 20     Fields:    Translation:Humans
    17. Chuang TD, Khorram O. miR-200c regulates IL8 expression by targeting IKBKB: a potential mediator of inflammation in leiomyoma pathogenesis. PLoS One. 2014; 9(4):e95370. PMID: 24755559.
      Citations: 18     Fields:    Translation:HumansCells
    18. Durrant LM, Khorram O, Buchholz JN, Pearce WJ. Maternal food restriction modulates cerebrovascular structure and contractility in adult rat offspring: effects of metyrapone. . 2014 Mar 15; 306(6):R401-10. PMID: 24477541.
      Citations:    
    19. Khorram O, Ghazi R, Chuang TD, Han G, Naghi J, Ni Y, Pearce WJ. Excess maternal glucocorticoids in response to in utero undernutrition inhibit offspring angiogenesis. Reprod Sci. 2014 May; 21(5):601-11. PMID: 24155066.
      Citations: 8     Fields:    Translation:AnimalsCells
    20. Rehan VK, Li Y, Corral J, Saraswat A, Husain S, Dhar A, Sakurai R, Khorram O, Torday JS. Metyrapone blocks maternal food restriction-induced changes in female rat offspring lung development. Reprod Sci. 2014 Apr; 21(4):517-25. PMID: 24023031.
      Citations: 7     Fields:    Translation:Animals
    21. Pearce WJ, Khorram O. Maturation and differentiation of the fetal vasculature. Clin Obstet Gynecol. 2013 Sep; 56(3):537-48. PMID: 23820122.
      Citations: 8     Fields:    Translation:HumansCells
    22. Hubbell MC, Semotiuk AJ, Thorpe RB, Adeoye OO, Butler SM, Williams JM, Khorram O, Pearce WJ. Chronic hypoxia and VEGF differentially modulate abundance and organization of myosin heavy chain isoforms in fetal and adult ovine arteries. . 2012 Nov 15; 303(10):C1090-103. PMID: 22992677.
      Citations:    
    23. Najafi T, Novin MG, Ghazi R, Khorram O. Altered endometrial expression of endothelial nitric oxide synthase in women with unexplained recurrent miscarriage and infertility. Reprod Biomed Online. 2012 Oct; 25(4):408-14. PMID: 22877939.
      Citations: 6     Fields:    Translation:HumansCells
    24. Butler SM, Abrassart JM, Hubbell MC, Adeoye O, Semotiuk A, Williams JM, Mata-Greenwood E, Khorram O, Pearce WJ. Contributions of VEGF to age-dependent transmural gradients in contractile protein expression in ovine carotid arteries. . 2011 Sep; 301(3):C653-66. PMID: 21653901.
      Citations:    
    25. Khorram NM, Magee TR, Wang C, Desai M, Ross M, Khorram O. Maternal undernutrition programs offspring adrenal expression of steroidogenic enzymes. Reprod Sci. 2011 Oct; 18(10):931-40. PMID: 21566243.
      Citations: 8     Fields:    Translation:Animals
    26. Khorram O, Han G, Magee T. Cigarette smoke inhibits endometrial epithelial cell proliferation through a nitric oxide-mediated pathway. Fertil Steril. 2010 Jan; 93(1):257-63. PMID: 19022425.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    27. Khorram O, Han G. Influence of progesterone on endometrial nitric oxide synthase expression. Fertil Steril. 2009 May; 91(5 Suppl):2157-62. PMID: 18710710.
      Citations: 8     Fields:    Translation:HumansCells
    28. Magee TR, Han G, Cherian B, Khorram O, Ross MG, Desai M. Down-regulation of transcription factor peroxisome proliferator-activated receptor in programmed hepatic lipid dysregulation and inflammation in intrauterine growth-restricted offspring. Am J Obstet Gynecol. 2008 Sep; 199(3):271.e1-5. PMID: 18667178.
      Citations: 26     Fields:    Translation:AnimalsCells
    29. Khorram O, Khorram N, Momeni M, Han G, Halem J, Desai M, Ross MG. Maternal undernutrition inhibits angiogenesis in the offspring: a potential mechanism of programmed hypertension. . 2007 Aug; 293(2):R745-53. PMID: 17507434.
      Citations:    
    30. Khorram O, Momeni M, Ferrini M, Desai M, Ross MG. In utero undernutrition in rats induces increased vascular smooth muscle content in the offspring. Am J Obstet Gynecol. 2007 May; 196(5):486.e1-8. PMID: 17466715.
      Citations: 7     Fields:    Translation:Animals
    31. Ross MG, Desai M, Khorram O, McKnight RA, Lane RH, Torday J. Gestational programming of offspring obesity: a potential contributor to Alzheimer's disease. Curr Alzheimer Res. 2007 Apr; 4(2):213-7. PMID: 17430249.
      Citations: 13     Fields:    Translation:HumansAnimals
    32. Khorram O, Momeni M, Desai M, Ross MG. Nutrient restriction in utero induces remodeling of the vascular extracellular matrix in rat offspring. Reprod Sci. 2007 Jan; 14(1):73-80. PMID: 17636219.
      Citations: 17     Fields:    Translation:AnimalsCells
    33. Salameh W, Helliwell JP, Han G, McPhaul L, Khorram O. Expression of endometrial glycogen synthase kinase-3beta protein throughout the menstrual cycle and its regulation by progesterone. Mol Hum Reprod. 2006 Sep; 12(9):543-9. PMID: 16882987.
      Citations: 6     Fields:    Translation:HumansCells
    34. Khorram O, Helliwell JP, Katz S, Bonpane CM, Jaramillo L. Two weeks of metformin improves clomiphene citrate-induced ovulation and metabolic profiles in women with polycystic ovary syndrome. Fertil Steril. 2006 May; 85(5):1448-51. PMID: 16579997.
      Citations: 8     Fields:    Translation:Humans
    35. Huang I, Jones J, Khorram O. Human seminal plasma nitric oxide: correlation with sperm morphology and testosterone. Med Sci Monit. 2006 Mar; 12(3):CR103-6. PMID: 16501419.
      Citations: 6     Fields:    Translation:HumansCells
    36. Han G, Magee T, Khorram O. Regulation of nitric oxide synthase isoforms by estrogen in the human endometrium. Fertil Steril. 2005 Oct; 84 Suppl 2:1220-7. PMID: 16210014.
      Citations: 4     Fields:    Translation:HumansCells
    37. Schwimmer JB, Khorram O, Chiu V, Schwimmer WB. Abnormal aminotransferase activity in women with polycystic ovary syndrome. Fertil Steril. 2005 Feb; 83(2):494-7. PMID: 15705403.
      Citations: 18     Fields:    Translation:Humans
    38. Ho MH, Bhatia NN, Khorram O. Physiologic role of nitric oxide and nitric oxide synthase in female lower urinary tract. Curr Opin Obstet Gynecol. 2004 Oct; 16(5):423-9. PMID: 15353953.
      Citations: 12     Fields:    Translation:Humans
    39. Khorram O, Garthwaite M, Jones J, Golos T. Expression of aryl hydrocarbon receptor (AHR) and aryl hydrocarbon receptor nuclear translocator (ARNT) mRNA expression in human spermatozoa. Med Sci Monit. 2004 May; 10(5):BR135-8. PMID: 15114261.
      Citations: 6     Fields:    Translation:HumansCells
    40. Katz S, Marshall J, Khorram O. An unusual case of ovarian resistance syndrome. Obstet Gynecol. 2003 May; 101(5 Pt 2):1078-82. PMID: 12738108.
      Citations: 1     Fields:    Translation:Humans
    41. Khorram O, Colman RJ, Kemnitz JW, Magness RR, Zhang J, Yao Z, Keller ET. The influence of sex hormones on circulating nitric oxide (NOx) levels in rhesus monkeys (Macaca Mulatta). Med Sci Monit. 2002 Dec; 8(12):BR489-95. PMID: 12503026.
      Citations: 2     Fields:    Translation:Animals
    42. Khorram O, Lessey BA. Alterations in expression of endometrial endothelial nitric oxide synthase and alpha(v)beta(3) integrin in women with endometriosis. Fertil Steril. 2002 Oct; 78(4):860-4. PMID: 12372469.
      Citations: 9     Fields:    Translation:HumansCells
    43. Ross MG, Khorram O. Recalculation of gestational sac losses in multifetal pregnancy. Am J Obstet Gynecol. 2002 Sep; 187(3):820-1; author reply 821. PMID: 12237672.
      Citations: 1     Fields:    Translation:Humans
    44. Khorram O. Nitric oxide and its role in blastocyst implantation. Rev Endocr Metab Disord. 2002 May; 3(2):145-9. PMID: 12007291.
      Citations: 8     Fields:    Translation:HumansAnimals
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