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Bradley Jones, PhD

TitleDirector, Computer Network Support Facility
Faculty RankAssociate Specialist
InstitutionUniversity of Hawaii
DepartmentPacific Biosciences Research Center
AddressUniversity of Hawaii
1993 East-West Road
Honolulu HI 96822
Phone8089566982
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    Collapse Research 
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    F32AI008404     (JONES, BRADLEY D)Jan 31, 1992
    NIH
    CYTOTOXIC T CELLS IN MURINE S. TYPHIMURIUM INFECTION
    Role: Principal Investigator

    R29AI038268     (JONES, BRADLEY D)Jul 1, 1995 - Jun 30, 2001
    NIH
    FUNCTIONAL ANALYSIS OF SALMONELLA INVASION PROTEINS
    Role: Principal Investigator

    R21AI059541     (JONES, BRADLEY D)Sep 30, 2004 - Sep 30, 2006
    NIH
    Salmonella Invasion Gene Regulation
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Martini AM, Moricz BS, Ripperger AK, Tran PM, Sharp ME, Forsythe AN, Kulhankova K, Salgado-Pabón W, Jones BD. Association of Novel Streptococcus sanguinis Virulence Factors With Pathogenesis in a Native Valve Infective Endocarditis Model. Front Microbiol. 2020; 11:10. PMID: 32082276.
      Citations:    
    2. Sudderuddin H, Kinloch NN, Jin SW, Miller RL, Jones BR, Brumme CJ, Joy JB, Brockman MA, Brumme ZL. Longitudinal within-host evolution of HIV Nef-mediated CD4, HLA and SERINC5 downregulation activity: a case study. Retrovirology. 2020 01 09; 17(1):3. PMID: 31918727.
      Citations: 4     Fields:    Translation:HumansCells
    3. Fletcher JR, Crane DD, Wehrly TD, Martens CA, Bosio CM, Jones BD. The Ability to Acquire Iron Is Inversely Related to Virulence and the Protective Efficacy of Francisella tularensis Live Vaccine Strain. Front Microbiol. 2018; 9:607. PMID: 29670588.
      Citations:    
    4. Kinkead LC, Whitmore LC, McCracken JM, Fletcher JR, Ketelsen BB, Kaufman JW, Jones BD, Weiss DS, Barker JH, Allen LH. Bacterial lipoproteins and other factors released by Francisella tularensis modulate human neutrophil lifespan: Effects of a TLR1 SNP on apoptosis inhibition. Cell Microbiol. 2018 02; 20(2). PMID: 29063667.
      Citations: 5     Fields:    Translation:HumansCells
    5. Faron M, Fletcher JR, Rasmussen JA, Apicella MA, Jones BD. Interactions of Francisella tularensis with Alveolar Type II Epithelial Cells and the Murine Respiratory Epithelium. PLoS One. 2015; 10(5):e0127458. PMID: 26010977.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    6. Rasmussen JA, Fletcher JR, Long ME, Allen LA, Jones BD. Characterization of Francisella tularensis Schu S4 mutants identified from a transposon library screened for O-antigen and capsule deficiencies. Front Microbiol. 2015; 6:338. PMID: 25999917.
      Citations:    
    7. Baxter MA, Jones BD. Two-component regulators control hilA expression by controlling fimZ and hilE expression within Salmonella enterica serovar Typhimurium. Infect Immun. 2015 Mar; 83(3):978-85. PMID: 25547794.
      Citations: 14     Fields:    Translation:Cells
    8. Workalemahu G, Wang H, Puan KJ, Nada MH, Kuzuyama T, Jones BD, Jin C, Morita CT. Metabolic engineering of Salmonella vaccine bacteria to boost human V?2Vd2 T cell immunity. J Immunol. 2014 Jul 15; 193(2):708-21. PMID: 24943221.
      Citations: 10     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    9. Jones BD, Faron M, Rasmussen JA, Fletcher JR. Uncovering the components of the Francisella tularensis virulence stealth strategy. Front Cell Infect Microbiol. 2014; 4:32. PMID: 24639953.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    10. Rasmussen JA, Post DM, Gibson BW, Lindemann SR, Apicella MA, Meyerholz DK, Jones BD. Francisella tularensis Schu S4 lipopolysaccharide core sugar and O-antigen mutants are attenuated in a mouse model of tularemia. Infect Immun. 2014 Apr; 82(4):1523-39. PMID: 24452684.
      Citations: 11     Fields:    Translation:AnimalsCells
    11. Faron M, Fletcher JR, Rasmussen JA, Long ME, Allen LA, Jones BD. The Francisella tularensis migR, trmE, and cphA genes contribute to F. tularensis pathogenicity island gene regulation and intracellular growth by modulation of the stress alarmone ppGpp. Infect Immun. 2013 Aug; 81(8):2800-11. PMID: 23716606.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    12. Long ME, Lindemann SR, Rasmussen JA, Jones BD, Allen LA. Disruption of Francisella tularensis Schu S4 iglI, iglJ, and pdpC genes results in attenuation for growth in human macrophages and in vivo virulence in mice and reveals a unique phenotype for pdpC. Infect Immun. 2013 Mar; 81(3):850-61. PMID: 23275090.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    13. Ulland TK, Janowski AM, Buchan BW, Faron M, Cassel SL, Jones BD, Sutterwala FS. Francisella tularensis live vaccine strain folate metabolism and pseudouridine synthase gene mutants modulate macrophage caspase-1 activation. Infect Immun. 2013 Jan; 81(1):201-8. PMID: 23115038.
      Citations: 10     Fields:    Translation:AnimalsCells
    14. Lindemann SR, Peng K, Long ME, Hunt JR, Apicella MA, Monack DM, Allen LA, Jones BD. Francisella tularensis Schu S4 O-antigen and capsule biosynthesis gene mutants induce early cell death in human macrophages. Infect Immun. 2011 Feb; 79(2):581-94. PMID: 21078861.
      Citations: 51     Fields:    Translation:HumansCells
    15. Ulland TK, Buchan BW, Ketterer MR, Fernandes-Alnemri T, Meyerholz DK, Apicella MA, Alnemri ES, Jones BD, Nauseef WM, Sutterwala FS. Cutting edge: mutation of Francisella tularensis mviN leads to increased macrophage absent in melanoma 2 inflammasome activation and a loss of virulence. J Immunol. 2010 Sep 01; 185(5):2670-4. PMID: 20679532.
      Citations: 43     Fields:    Translation:AnimalsCells
    16. McCaffrey RL, Schwartz JT, Lindemann SR, Moreland JG, Buchan BW, Jones BD, Allen LA. Multiple mechanisms of NADPH oxidase inhibition by type A and type B Francisella tularensis. J Leukoc Biol. 2010 Oct; 88(4):791-805. PMID: 20610796.
      Citations: 47     Fields:    Translation:HumansCells
    17. Apicella MA, Post DM, Fowler AC, Jones BD, Rasmussen JA, Hunt JR, Imagawa S, Choudhury B, Inzana TJ, Maier TM, Frank DW, Zahrt TC, Chaloner K, Jennings MP, McLendon MK, Gibson BW. Identification, characterization and immunogenicity of an O-antigen capsular polysaccharide of Francisella tularensis. PLoS One. 2010 Jul 06; 5(7):e11060. PMID: 20625403.
      Citations: 47     Fields:    Translation:AnimalsCells
    18. Quandt SA, Jones BT, Talton JW, Whalley LE, Galván L, Vallejos QM, Grzywacz JG, Chen H, Pharr KE, Isom S, Arcury TA. Heavy metals exposures among Mexican farmworkers in eastern North Carolina. Environ Res. 2010 Jan; 110(1):83-8. PMID: 19818439.
      Citations: 12     Fields:    Translation:HumansPHPublic Health
    19. Buchan BW, McCaffrey RL, Lindemann SR, Allen LA, Jones BD. Identification of migR, a regulatory element of the Francisella tularensis live vaccine strain iglABCD virulence operon required for normal replication and trafficking in macrophages. Infect Immun. 2009 Jun; 77(6):2517-29. PMID: 19349423.
      Citations: 47     Fields:    Translation:HumansCells
    20. Schulert GS, McCaffrey RL, Buchan BW, Lindemann SR, Hollenback C, Jones BD, Allen LA. Francisella tularensis genes required for inhibition of the neutrophil respiratory burst and intramacrophage growth identified by random transposon mutagenesis of strain LVS. Infect Immun. 2009 Apr; 77(4):1324-36. PMID: 19204089.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    21. Buchan BW, McLendon MK, Jones BD. Identification of differentially regulated francisella tularensis genes by use of a newly developed Tn5-based transposon delivery system. Appl Environ Microbiol. 2008 May; 74(9):2637-45. PMID: 18344342.
      Citations: 27     Fields:    Translation:Cells
    22. Lindemann SR, McLendon MK, Apicella MA, Jones BD. An in vitro model system used to study adherence and invasion of Francisella tularensis live vaccine strain in nonphagocytic cells. Infect Immun. 2007 Jun; 75(6):3178-82. PMID: 17339345.
      Citations: 26     Fields:    Translation:HumansCells
    23. Ledeboer NA, Frye JG, McClelland M, Jones BD. Salmonella enterica serovar Typhimurium requires the Lpf, Pef, and Tafi fimbriae for biofilm formation on HEp-2 tissue culture cells and chicken intestinal epithelium. Infect Immun. 2006 Jun; 74(6):3156-69. PMID: 16714543.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    24. Ezer M, Elwood SA, Jones BT, Simeonsson JB. Evaluation of a tungsten coil atomization-laser-induced fluorescence detection approach for trace elemental analysis. Anal Chim Acta. 2006 Jun 30; 571(1):136-41. PMID: 17723431.
      Citations: 1     Fields:    
    25. Esteves CL, Jones BD, Clegg S. Biofilm formation by Salmonella enterica serovar Typhimurium and Escherichia coli on epithelial cells following mixed inoculations. Infect Immun. 2005 Aug; 73(8):5198-203. PMID: 16041039.
      Citations: 5     Fields:    Translation:HumansCells
    26. Ledeboer NA, Jones BD. Exopolysaccharide sugars contribute to biofilm formation by Salmonella enterica serovar typhimurium on HEp-2 cells and chicken intestinal epithelium. J Bacteriol. 2005 May; 187(9):3214-26. PMID: 15838049.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    27. Baxter MA, Jones BD. The fimYZ genes regulate Salmonella enterica Serovar Typhimurium invasion in addition to type 1 fimbrial expression and bacterial motility. Infect Immun. 2005 Mar; 73(3):1377-85. PMID: 15731035.
      Citations: 30     Fields:    Translation:HumansCells
    28. Jones BD. Salmonella invasion gene regulation: a story of environmental awareness. J Microbiol. 2005 Feb; 43 Spec No:110-7. PMID: 15765064.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    29. Boddicker JD, Jones BD. Lon protease activity causes down-regulation of Salmonella pathogenicity island 1 invasion gene expression after infection of epithelial cells. Infect Immun. 2004 Apr; 72(4):2002-13. PMID: 15039320.
      Citations: 37     Fields:    Translation:HumansCells
    30. Baxter MA, Fahlen TF, Wilson RL, Jones BD. HilE interacts with HilD and negatively regulates hilA transcription and expression of the Salmonella enterica serovar Typhimurium invasive phenotype. Infect Immun. 2003 Mar; 71(3):1295-305. PMID: 12595445.
      Citations: 55     Fields:    Translation:HumansCells
    31. Boddicker JD, Knosp BM, Jones BD. Transcription of the Salmonella invasion gene activator, hilA, requires HilD activation in the absence of negative regulators. J Bacteriol. 2003 Jan; 185(2):525-33. PMID: 12511499.
      Citations: 33     Fields:    Translation:HumansCells
    32. Boddicker JD, Ledeboer NA, Jagnow J, Jones BD, Clegg S. Differential binding to and biofilm formation on, HEp-2 cells by Salmonella enterica serovar Typhimurium is dependent upon allelic variation in the fimH gene of the fim gene cluster. Mol Microbiol. 2002 Sep; 45(5):1255-65. PMID: 12207694.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
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