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Chuan (River) Xiao

Faculty RankAssociate Professor
InstitutionUniversity of Texas at El Paso
Address500 West University
Department of Chemistry
El Paso TX 79968
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    I am a structural biologist who has extensive experience working on virus structures. My lab combines X-ray crystallography and cryo-electron microscopy (cryo-EM) to determine virus structures in order to understand their assembly and infection mechanism. The virus systems that under investigation include common cold viruses and marine viruses. Besides studying structures of intact viruses, Dr. Xiao is currently also working with protein structures related to viral SUMOlyation, viral DNA repair and viral DNA topoisomerization. In addition to virology projects, my lab is also interested in working with structures related to circadian rhythm, antibodies agaisnt glycans, and plant photosystems.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Xiao C, Fischer MG, Bolotaulo DM, Ulloa-Rondeau N, Avila GA, Suttle CA. Cryo-EM reconstruction of the Cafeteria roenbergensis virus capsid suggests novel assembly pathway for giant viruses. Sci Rep. 2017 07 14; 7(1):5484. PMID: 28710447.
      Citations: 6     Fields:    Translation:Cells
    2. Xiao C, Rossmann MG. Structures of giant icosahedral eukaryotic dsDNA viruses. Curr Opin Virol. 2011 Aug; 1(2):101-9. PMID: 21909343.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    3. Hildenbrand ZL, Molugu SK, Herrera N, Ramirez C, Xiao C, Bernal RA. Hsp90 can accommodate the simultaneous binding of the FKBP52 and HOP proteins. Oncotarget. 2011 Jan-Feb; 2(1-2):43-58. PMID: 21378414.
      Citations: 16     Fields:    Translation:HumansCells
    4. Hildenbrand ZL, Molugu SK, Paul A, Avila GA, Herrera N, Xiao C, Cox MB, Bernal RA. High-yield expression and purification of the Hsp90-associated p23, FKBP52, HOP and SGTa proteins. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Oct 15; 878(28):2760-4. PMID: 20829124.
      Citations: 2     Fields:    Translation:HumansCells
    5. Klose T, Kuznetsov YG, Xiao C, Sun S, McPherson A, Rossmann MG. The three-dimensional structure of Mimivirus. Intervirology. 2010; 53(5):268-73. PMID: 20551678.
      Citations: 21     Fields:    Translation:Cells
    6. Cherrier MV, Kostyuchenko VA, Xiao C, Bowman VD, Battisti AJ, Yan X, Chipman PR, Baker TS, Van Etten JL, Rossmann MG. An icosahedral algal virus has a complex unique vertex decorated by a spike. Proc Natl Acad Sci U S A. 2009 Jul 07; 106(27):11085-9. PMID: 19541619.
      Citations: 34     Fields:    Translation:Cells
    7. Xiao C, Kuznetsov YG, Sun S, Hafenstein SL, Kostyuchenko VA, Chipman PR, Suzan-Monti M, Raoult D, McPherson A, Rossmann MG. Structural studies of the giant mimivirus. PLoS Biol. 2009 Apr 28; 7(4):e92. PMID: 19402750.
      Citations: 59     Fields:    Translation:Cells
    8. Zauberman N, Mutsafi Y, Halevy DB, Shimoni E, Klein E, Xiao C, Sun S, Minsky A. Distinct DNA exit and packaging portals in the virus Acanthamoeba polyphaga mimivirus. PLoS Biol. 2008 May 13; 6(5):e114. PMID: 18479185.
      Citations: 62     Fields:    Translation:AnimalsCells
    9. Hafenstein S, Palermo LM, Kostyuchenko VA, Xiao C, Morais MC, Nelson CD, Bowman VD, Battisti AJ, Chipman PR, Parrish CR, Rossmann MG. Asymmetric binding of transferrin receptor to parvovirus capsids. Proc Natl Acad Sci U S A. 2007 Apr 17; 104(16):6585-9. PMID: 17420467.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    10. Rossmann MG, Arisaka F, Battisti AJ, Bowman VD, Chipman PR, Fokine A, Hafenstein S, Kanamaru S, Kostyuchenko VA, Mesyanzhinov VV, Shneider MM, Morais MC, Leiman PG, Palermo LM, Parrish CR, Xiao C. From structure of the complex to understanding of the biology. Acta Crystallogr D Biol Crystallogr. 2007 Jan; 63(Pt 1):9-16. PMID: 17164521.
      Citations: 7     Fields:    Translation:Cells
    11. Pokidysheva E, Zhang Y, Battisti AJ, Bator-Kelly CM, Chipman PR, Xiao C, Gregorio GG, Hendrickson WA, Kuhn RJ, Rossmann MG. Cryo-EM reconstruction of dengue virus in complex with the carbohydrate recognition domain of DC-SIGN. Cell. 2006 Feb 10; 124(3):485-93. PMID: 16469696.
      Citations: 116     Fields:    Translation:HumansCells
    12. Xiao C, Chipman PR, Battisti AJ, Bowman VD, Renesto P, Raoult D, Rossmann MG. Cryo-electron microscopy of the giant Mimivirus. J Mol Biol. 2005 Oct 28; 353(3):493-6. PMID: 16185710.
      Citations: 43     Fields:    Translation:Cells
    13. Xiao C, Bator-Kelly CM, Rieder E, Chipman PR, Craig A, Kuhn RJ, Wimmer E, Rossmann MG. The crystal structure of coxsackievirus A21 and its interaction with ICAM-1. Structure. 2005 Jul; 13(7):1019-33. PMID: 16004874.
      Citations: 37     Fields:    Translation:HumansCells
    14. Xiao C, Tuthill TJ, Bator Kelly CM, Challinor LJ, Chipman PR, Killington RA, Rowlands DJ, Craig A, Rossmann MG. Discrimination among rhinovirus serotypes for a variant ICAM-1 receptor molecule. J Virol. 2004 Sep; 78(18):10034-44. PMID: 15331736.
      Citations: 10     Fields:    Translation:HumansCells
    15. Xiao C, Bator CM, Bowman VD, Rieder E, He Y, H├ębert B, Bella J, Baker TS, Wimmer E, Kuhn RJ, Rossmann MG. Interaction of coxsackievirus A21 with its cellular receptor, ICAM-1. J Virol. 2001 Mar; 75(5):2444-51. PMID: 11160747.
      Citations: 34     Fields:    Translation:HumansCells
    16. Xiao C, Xin H, Dong A, Sun C, Cao K. A novel calmodulin-like protein gene in rice which has an unusual prolonged C-terminal sequence carrying a putative prenylation site. DNA Res. 1999 Jun 30; 6(3):179-81. PMID: 10470849.
      Citations: 8     Fields:    Translation:AnimalsCells
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    RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

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