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Manuel Llano

Faculty RankAssociate Professor
InstitutionUniversity of Texas at El Paso
AddressEl Paso TX
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Valdez F, Salvador J, Palermo PM, Mohl JE, Hanley KA, Watts D, Llano M. Schlafen 11 Restricts Flavivirus Replication. J Virol. 2019 08 01; 93(15). PMID: 31118262.
      Citations: 9     Fields:    Translation:HumansCells
    2. Castro E, Cerón MR, Garcia AH, Kim Q, Etcheverry-Berríos A, Morel M, Díaz-Torres R, Qian W, Martinez Z, Mendez L, Perez F, Santoyo CA, Gimeno-Muñoz R, Esper R, Gutierrez DA, Varela-Ramirez A, Aguilera RJ, Llano M, Soler M, Aliaga-Alcalde N, Echegoyen L. A new family of fullerene derivatives: Fullerene-curcumin conjugates for biological and photovoltaic applications. RSC Adv. 2018; 8(73):41692-41698. PMID: 31543960.
    3. Píchalová R, Füzik T, Vokatá B, Rumlová M, Llano M, Dostálková A, Krížová I, Ruml T, Ulbrich P. Conserved cysteines in Mason-Pfizer monkey virus capsid protein are essential for infectious mature particle formation. Virology. 2018 08; 521:108-117. PMID: 29906704.
      Citations:    Fields:    Translation:HumansCells
    4. Llano M, Peña-Hernandez MA. Defining Pharmacological Targets by Analysis of Virus-Host Protein Interactions. Adv Protein Chem Struct Biol. 2018; 111:223-242. PMID: 29459033.
      Citations:    Fields:    Translation:HumansCells
    5. Bueno MTD, Reyes D, Llano M. LEDGF/p75 Deficiency Increases Deletions at the HIV-1 cDNA Ends. Viruses. 2017 09 15; 9(9). PMID: 28914817.
      Citations:    Fields:    Translation:HumansCells
    6. Matysiak J, Lesbats P, Mauro E, Lapaillerie D, Dupuy JW, Lopez AP, Benleulmi MS, Calmels C, Andreola ML, Ruff M, Llano M, Delelis O, Lavigne M, Parissi V. Modulation of chromatin structure by the FACT histone chaperone complex regulates HIV-1 integration. Retrovirology. 2017 Jul 28; 14(1):39. PMID: 28754126.
      Citations: 7     Fields:    Translation:HumansCells
    7. Castro E, Martinez ZS, Seong CS, Cabrera-Espinoza A, Ruiz M, Hernandez Garcia A, Valdez F, Llano M, Echegoyen L. Characterization of New Cationic N,N-Dimethyl[70]fulleropyrrolidinium Iodide Derivatives as Potent HIV-1 Maturation Inhibitors. J Med Chem. 2016 12 22; 59(24):10963-10973. PMID: 28002960.
      Citations: 5     Fields:    Translation:HumansCells
    8. Martinez ZS, Castro E, Seong CS, Cerón MR, Echegoyen L, Llano M. Fullerene Derivatives Strongly Inhibit HIV-1 Replication by Affecting Virus Maturation without Impairing Protease Activity. Antimicrob Agents Chemother. 2016 10; 60(10):5731-41. PMID: 27431232.
      Citations: 11     Fields:    Translation:HumansCells
    9. Lopez AP, Kugelman JR, Garcia-Rivera J, Urias E, Salinas SA, Fernandez-Zapico ME, Llano M. The Structure-Specific Recognition Protein 1 Associates with Lens Epithelium-Derived Growth Factor Proteins and Modulates HIV-1 Replication. J Mol Biol. 2016 Jul 17; 428(14):2814-31. PMID: 27216501.
      Citations: 3     Fields:    Translation:HumansCells
    10. Gutierrez DA, Valdes L, Serguera C, Llano M. Poly(ADP-ribose) polymerase-1 silences retroviruses independently of viral DNA integration or heterochromatin formation. J Gen Virol. 2016 07; 97(7):1686-1692. PMID: 27028089.
      Citations: 5     Fields:    Translation:AnimalsCells
    11. Leitz J, Reuschenbach M, Lohrey C, Honegger A, Accardi R, Tommasino M, Llano M, von Knebel Doeberitz M, Hoppe-Seyler K, Hoppe-Seyler F. Oncogenic human papillomaviruses activate the tumor-associated lens epithelial-derived growth factor (LEDGF) gene. PLoS Pathog. 2014 Mar; 10(3):e1003957. PMID: 24604027.
      Citations: 12     Fields:    Translation:HumansCells
    12. Bueno MT, Reyes D, Valdes L, Saheba A, Urias E, Mendoza C, Fregoso OI, Llano M. Poly(ADP-ribose) polymerase 1 promotes transcriptional repression of integrated retroviruses. J Virol. 2013 Mar; 87(5):2496-507. PMID: 23255787.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    13. Astiazaran P, Bueno MT, Morales E, Kugelman JR, Garcia-Rivera JA, Llano M. HIV-1 integrase modulates the interaction of the HIV-1 cellular cofactor LEDGF/p75 with chromatin. Retrovirology. 2011 Apr 21; 8:27. PMID: 21510906.
      Citations: 2     Fields:    Translation:HumansCells
    14. Bueno MT, Garcia-Rivera JA, Kugelman JR, Morales E, Rosas-Acosta G, Llano M. SUMOylation of the lens epithelium-derived growth factor/p75 attenuates its transcriptional activity on the heat shock protein 27 promoter. J Mol Biol. 2010 Jun 04; 399(2):221-39. PMID: 20382164.
      Citations: 13     Fields:    Translation:HumansCells
    15. Garcia-Rivera JA, Bueno MT, Morales E, Kugelman JR, Rodriguez DF, Llano M. Implication of serine residues 271, 273, and 275 in the human immunodeficiency virus type 1 cofactor activity of lens epithelium-derived growth factor/p75. J Virol. 2010 Jan; 84(2):740-52. PMID: 19889764.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    16. Meehan AM, Saenz DT, Morrison JH, Garcia-Rivera JA, Peretz M, Llano M, Poeschla EM. LEDGF/p75 proteins with alternative chromatin tethers are functional HIV-1 cofactors. PLoS Pathog. 2009 Jul; 5(7):e1000522. PMID: 19609362.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    17. Llano M, Gaznick N, Poeschla EM. Rapid, controlled and intensive lentiviral vector-based RNAi. Methods Mol Biol. 2009; 485:257-70. PMID: 19020831.
      Citations: 4     Fields:    Translation:HumansCells
    18. Llano M, Morrison J, Poeschla EM. Virological and cellular roles of the transcriptional coactivator LEDGF/p75. Curr Top Microbiol Immunol. 2009; 339:125-46. PMID: 20012527.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    19. Miest T, Saenz D, Meehan A, Llano M, Poeschla EM. Intensive RNAi with lentiviral vectors in mammalian cells. Methods. 2009 Apr; 47(4):298-303. PMID: 19041944.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    20. Marshall HM, Ronen K, Berry C, Llano M, Sutherland H, Saenz D, Bickmore W, Poeschla E, Bushman FD. Role of PSIP1/LEDGF/p75 in lentiviral infectivity and integration targeting. PLoS One. 2007 Dec 19; 2(12):e1340. PMID: 18092005.
      Citations: 132     Fields:    Translation:HumansAnimalsCells
    21. Llano M, Saenz DT, Meehan A, Wongthida P, Peretz M, Walker WH, Teo W, Poeschla EM. An essential role for LEDGF/p75 in HIV integration. Science. 2006 Oct 20; 314(5798):461-4. PMID: 16959972.
      Citations: 254     Fields:    Translation:HumansCells
    22. Llano M, Vanegas M, Hutchins N, Thompson D, Delgado S, Poeschla EM. Identification and characterization of the chromatin-binding domains of the HIV-1 integrase interactor LEDGF/p75. J Mol Biol. 2006 Jul 21; 360(4):760-73. PMID: 16793062.
      Citations: 95     Fields:    Translation:HumansCells
    23. Ciuffi A, Llano M, Poeschla E, Hoffmann C, Leipzig J, Shinn P, Ecker JR, Bushman F. A role for LEDGF/p75 in targeting HIV DNA integration. Nat Med. 2005 Dec; 11(12):1287-9. PMID: 16311605.
      Citations: 297     Fields:    Translation:HumansCells
    24. Vanegas M, Llano M, Delgado S, Thompson D, Peretz M, Poeschla E. Identification of the LEDGF/p75 HIV-1 integrase-interaction domain and NLS reveals NLS-independent chromatin tethering. J Cell Sci. 2005 Apr 15; 118(Pt 8):1733-43. PMID: 15797927.
      Citations: 92     Fields:    Translation:HumansAnimalsCells
    25. Llano M, Delgado S, Vanegas M, Poeschla EM. Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase. J Biol Chem. 2004 Dec 31; 279(53):55570-7. PMID: 15475359.
      Citations: 68     Fields:    Translation:HumansCells
    26. Llano M, Vanegas M, Fregoso O, Saenz D, Chung S, Peretz M, Poeschla EM. LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes. J Virol. 2004 Sep; 78(17):9524-37. PMID: 15308744.
      Citations: 156     Fields:    Translation:HumansCells
    27. Nguyen KL, llano M, Akari H, Miyagi E, Poeschla EM, Strebel K, Bour S. Codon optimization of the HIV-1 vpu and vif genes stabilizes their mRNA and allows for highly efficient Rev-independent expression. Virology. 2004 Feb 20; 319(2):163-75. PMID: 15015498.
      Citations: 111     Fields:    Translation:HumansCells
    28. Llano M, Kelly T, Vanegas M, Peretz M, Peterson TE, Simari RD, Poeschla EM. Blockade of human immunodeficiency virus type 1 expression by caveolin-1. J Virol. 2002 Sep; 76(18):9152-64. PMID: 12186899.
      Citations: 16     Fields:    Translation:HumansCells
    29. García P, Llano M, de Heredia AB, Willberg CB, Caparrós E, Aparicio P, Braud VM, López-Botet M. Human T cell receptor-mediated recognition of HLA-E. Eur J Immunol. 2002 04; 32(4):936-44. PMID: 11920559.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
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