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Yasuhiro Yamamura
Title Director, AIDS Research Program
Faculty Rank Professor
Degree Ph.D.
Institution Ponce School of Medicine
Department Microbiology
Clusters HIV/AIDS
Address
395 Industrial reparada-2
City Ponce
State PR
Postal Code 00716-2348
Telephone 7878415150
Fax 7878415159
Email
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  Research projects funded by the National Institutes of Health (NIH), the Centers for Disease Control (CDC), the Food and Drug Administration (FDA), and the Department of Veterans Affairs (VA)

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1.
2018AIDS Core5G12MD007579-33
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2017AIDS Core5G12MD007579-32
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2016AIDS Core5G12MD007579-31
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2015AIDS Core5G12MD007579-30
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2014AIDS Core2G12MD007579-29
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2009PR COMPREHENSIVE CTR FOR HIV DISPARITIES: PSM: LAB CORE3U54RR019507-06S1
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2008PR COMPREHENSIVE CTR FOR HIV DISPARITIES: PSM: LAB CORE5U54RR019507-06
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2007PR COMPREHENSIVE CTR FOR HIV DISPARITIES: PSM: LAB CORE5U54RR019507-05
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2006FACULTY RECRUITMENT &DEVELOPMENT CORE5G12RR003050-22
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2006ADMINISTRATIVE CORE5G12RR003050-22
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2006AIDS RESEARCH CORE5G12RR003050-22
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2006PR COMPREHENSIVE CTR FOR HIV DISPARITIES: PSM: LAB CORE5U54RR019507-04
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2005FACULTY RECRUITMENT CORE5G12RR003050-21
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2005ADMINISTRATIVE CORE5G12RR003050-21
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2005AIDS RESEARCH CORE5G12RR003050-21
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2005PR COMPREHENSIVE CTR FOR HIV DISPARITIES: PSM: LAB CORE5U54RR019507-03
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2004CORE--FACULTY RECRUITMENT5G12RR003050-20
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2004PR COMPREHENSIVE CTR FOR HIV DISPARITIES: PSM: LAB CORE5U54RR019507-02
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2004CORE--AIDS RESEARCH5G12RR003050-20
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2002AIDS INFRASTRUCTURE: HIV EPIDEMIOLGY: DRUG ABUSE: CYTOKINE: PUERTO RICO3G12RR003050-18S1
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2002MATERNAL DRUG USE &PLACENTAL LEAKAGE: PERINATAL HIV TRANSMISSION: HISPANIC5G12RR003050-18
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2002Genital HIV-1 Compartment in Heterosexual Transmission5S06GM008239-17
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2002Genital HIV-1 Compartment in Heterosexual Transmission3S06GM008239-17S1
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2002AIDS INFRASTRUCTURE: HIV EPIDEMIOLGY: DRUG ABUSE: CYTOKINE: PUERTO RICO5G12RR003050-18
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2002MATERNAL DRUG USE &PLACENTAL LEAKAGE: PERINATAL HIV TRANSMISSION: HISPANIC3G12RR003050-18S1
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2002Genital HIV-1 Compartment in Heterosexual Transmission3S06GM008239-16S2
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2002Genital HIV-1 Compartment in Heterosexual Transmission3S06GM008239-17S2
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2002Genital HIV-1 Compartment in Heterosexual Transmission3S06GM008239-17S3
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2001MATERNAL DRUG USE &PLACENTAL LEAKAGE: PERINATAL HIV TRANSMISSION: HISPANIC5G12RR003050-17
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2001AIDS INFRASTRUCTURE: HIV EPIDEMIOLGY: DRUG ABUSE: CYTOKINE: PUERTO RICO5G12RR003050-17
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2001Genital HIV-1 Compartment in Heterosexual Transmission2S06GM008239-16
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2000AIDS INFRASTRUCTURE: HIV EPIDEMIOLGY: DRUG ABUSE: CYTOKINE: PUERTO RICO3G12RR003050-15S1
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2000MATERNAL DRUG USE &PLACENTAL LEAKAGE: PERINATAL HIV TRANSMISSION: HISPANIC3G12RR003050-15S1
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1999MATERNAL DRUG USE &PLACENTAL LEAKAGE: PERINATAL HIV TRANSMISSION: HISPANIC5G12RR003050-15
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1999AIDS INFRASTRUCTURE: HIV &HCV EPIDEMIOLGY: DRUG RESISTANCE: PUERTO RICO5G12RR003050-15
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1998AIDS INFRASTRUCTURE: HIV EPIDEMIOLGY: DRUG ABUSE: CYTOKINE: PUERTO RICO5G12RR003050-14
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1998MATERNAL DRUG USE &PLACENTAL LEAKAGE: PERINATAL HIV TRANSMISSION: HISPANIC5G12RR003050-14
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1997MATERNAL DRUG ABUSE W PREGNANCY: LEAKY PLACENTA: PERINATAL HIV TRANSMISSN5G12RR003050-13
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1997AIDS INFRASTRUCTURE: HIV EPIDEMIOLGY: DRUG ABUSE: CYTOKINE: PUERTO RICO5G12RR003050-13
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1996RCMI AIDS INFRASTRUCTURE PROGRAM5G12RR003050-12
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1996MATERNAL DRUG USE, PLACENTA LEAKAGE AND PERINATAL HIV INFECTION5G12RR003050-12
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1994HTLV I AND AIDS IN PUERTO RICAN IV DRUG USERS5R01DA006037-05
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1993HTLV-I AND AIDS IN PUERTO RICAN I.V. DRUG USERS5R01DA006037-04
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1992HTLV-I AND AIDS IN PUERTO RICAN I.V. DRUG USERS5R01DA006037-03
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1991HTLV-I AND AIDS IN PUERTO RICAN I.V. DRUG USERS5R01DA006037-02
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1990HTLV-I AND AIDS IN PUERTO RICAN I.V. DRUG USERS1R01DA006037-01A1

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1. Lopez P, De Jesus O, Yamamura Y, Rodriguez N, Arias A, Sanchez R, Rodriguez Y, Tamayo-Agrait V, Cuevas W, Rivera-Amill V. Molecular Epidemiology of HIV-1 virus in Puerto Rico: Novel Cases of HIV-1 Subtype C, D and CRF-24BG. AIDS Res Hum Retroviruses. 2018 Apr 15.
2. Oishi T, Takehara S, Yamamura Y, Tomida M, Ito S, Kuriki K, Namba H. "Pure" Suprasellar Schwannoma Presented with Communicating Hydrocephalus: A Case Report. NMC Case Rep J. 2017 Jul; 4(3):83-87.
3. Oishi T, Takehara S, Yamamura Y, Tomida M, Ikegaya N, Seki G, Ohta N. [Hemodialysis Increases the Incidence of Post-Traumatic Seizure in Hemodialysis Patients with Traumatic Intracranial Hemorrhage]. No Shinkei Geka. 2017 Apr; 45(4):303-309.
4. Bernabe-Dones RD, Gonzalez-Pons M, Villar-Prados A, Lacourt-Ventura M, Rodríguez-Arroyo H, Fonseca-Williams S, Velazquez FE, Diaz-Algorri Y, Lopez-Diaz SM, Rodríguez N, Yamamura Y, Cruz-Correa M. High Prevalence of Human Papillomavirus in Colorectal Cancer in Hispanics: A Case-Control Study. Gastroenterol Res Pract. 2016; 2016:7896716.
5. López P, Rivera-Amill V, Rodríguez N, Vargas F, Yamamura Y. The Genetic Diversity and Evolution of HIV-1 Subtype B Epidemic in Puerto Rico. Int J Environ Res Public Health. 2015 Dec 23; 13(1):ijerph13010055.
6. López P, Rivera-Amill V, Paulino-Ramirez R, Yamamura Y. Short Communication: HIV-1 Subtype B in the Dominican Republic: Evolution and Molecular Epidemiology. AIDS Res Hum Retroviruses. 2015 Jul; 31(7):679-84.
7. Morales-Vásquez L, Miranda-Avalo EI, Rodríguez-Medina JR, Quiñones-Badillo Y, Marqués-Lespier J, Muñoz-Acabá J, Pastrana R, Pérez-Cardona CM, Yamamura Y, Torres EA. Demographics, clinical characteristics, IFNL3- and IFNL4- polymorphisms in a cohort of hepatitis C patients from Puerto Rico. P R Health Sci J. 2014 Dec; 33(4):177-83.
8. Rivera-Rivera Y, García Y, Toro V, Cappas N, López P, Yamamura Y, Rivera-Amill V. Depression Correlates with Increased Plasma Levels of Inflammatory Cytokines and a Dysregulated Oxidant/Antioxidant Balance in HIV-1-Infected Subjects Undergoing Antiretroviral Therapy. J Clin Cell Immunol. 2014 Dec; 5(6).
9. Isidro RA, Bonilla FJ, Pagan H, Cruz ML, Lopez P, Godoy L, Hernandez S, Loucil-Alicea RY, Rivera-Amill V, Yamamura Y, Isidro AA, Appleyard CB. The Probiotic Mixture VSL#3 Alters the Morphology and Secretion Profile of Both Polarized and Unpolarized Human Macrophages in a Polarization-Dependent Manner. J Clin Cell Immunol. 2014 Jun 20; 5(3):1000227.
10. Tang Q, Roan NR, Yamamura Y. Seminal plasma and semen amyloids enhance cytomegalovirus infection in cell culture. J Virol. 2013 Dec; 87(23):12583-91.
11. Barrow GJ, Hylton-Kong T, Rodriguez N, Yamamura Y, Figueroa JP. HIV-1 drug resistance in treatment-naive chronically infected patients in Jamaica. Antivir Ther. 2013; 18(7):941-4.
12. Contreras-Galindo R, Kaplan MH, Contreras-Galindo AC, Gonzalez-Hernandez MJ, Ferlenghi I, Giusti F, Lorenzo E, Gitlin SD, Dosik MH, Yamamura Y, Markovitz DM. Characterization of human endogenous retroviral elements in the blood of HIV-1-infected individuals. J Virol. 2012 Jan; 86(1):262-76.
13. Perez R, Gibson S, Lopez P, Koenig E, De Castro M, Yamamura Y. Distribution of HIV-1 infection in different T lymphocyte subsets: antiretroviral therapy-naïve vs. experienced patients. AIDS Res Hum Retroviruses. 2011 Apr; 27(4):399-410.
14. Yamamura Y. The long journey to the discovery of PARK2: The 50th Anniversary of Japanese Society of Neuropathology. Neuropathology. 2010 Oct; 30(5):495-500.
15. Kang KH, Yamamura Y, Carlos MP, Karvelas N, Kim IS, Sunkara D, Rivera R, Gardner MB, Anderson DE, Diaz-Mitoma F, Torres J, Marquez JP. Synthetic antigens representing the antigenic variation of human hepatitis C virus. Viral Immunol. 2010 Oct; 23(5):497-508.
16. Yamada H, Shinmura K, Yamamura Y, Kurachi K, Nakamura T, Tsuneyoshi T, Yokota N, Maekawa M, Sugimura H. Identification and characterization of a novel germline p53 mutation in a patient with glioblastoma and colon cancer. Int J Cancer. 2009 Aug 15; 125(4):973-6.
17. Ding M, Tarwater P, Rodriguez M, Chatterjee R, Ratner D, Yamamura Y, Roy P, Mellors J, Neogi D, Chen Y, Gupta P. Estimation of the predictive role of plasma viral load on CD4 decline in HIV-1 subtype C-infected subjects in India. J Acquir Immune Defic Syndr. 2009 Feb 01; 50(2):119-25.
18. Cosme RS, Yamamura Y, Tang Q. Roles of polypyrimidine tract binding proteins in major immediate-early gene expression and viral replication of human cytomegalovirus. J Virol. 2009 Apr; 83(7):2839-50.
19. Rodríguez N, Vargas Vidot J, Panelli J, Colón H, Ritchie B, Yamamura Y. GC-MS confirmation of xylazine (Rompun), a veterinary sedative, in exchanged needles. Drug Alcohol Depend. 2008 Aug 01; 96(3):290-3.
20. Sánchez Mdel C, López P, Vélez R, Yamamura Y. P-glycoprotein expression in HTLV-III cells after treatment with HIV-1 protease inhibitors. Ethn Dis. 2008; 18(2 Suppl 2):S2-60-4.
21. Vélez R, Sánchez Mdel C, Lopez P, Yamamura Y. A new procedure for the quantitative assessment of p-glycoprotein efflux pump associated with human T lymphocytes. Ethn Dis. 2008; 18(2 Suppl 2):S2-75-80.
22. Yamamura Y. [The long journey to the discovery of PARK2]. Rinsho Shinkeigaku. 2007 Nov; 47(11):749-51.
23. Contreras-Galindo R, Almodóvar-Camacho S, González-Ramírez S, Lorenzo E, Yamamura Y. Comparative longitudinal studies of HERV-K and HIV-1 RNA titers in HIV-1-infected patients receiving successful versus unsuccessful highly active antiretroviral therapy. AIDS Res Hum Retroviruses. 2007 Sep; 23(9):1083-6.
24. Contreras-Galindo R, López P, Vélez R, Yamamura Y. HIV-1 infection increases the expression of human endogenous retroviruses type K (HERV-K) in vitro. AIDS Res Hum Retroviruses. 2007 Jan; 23(1):116-22.
25. Dayan GH, Thorley M, Yamamura Y, Rodríguez N, McLaughlin S, Torres LM, Seda A, Carbia M, Alexander LN, Caceres V, Pallansch MA. Serologic response to inactivated poliovirus vaccine: a randomized clinical trial comparing 2 vaccination schedules in Puerto Rico. J Infect Dis. 2007 Jan 01; 195(1):12-20.
26. Contreras-Galindo R, Kaplan MH, Markovitz DM, Lorenzo E, Yamamura Y. Detection of HERV-K(HML-2) viral RNA in plasma of HIV type 1-infected individuals. AIDS Res Hum Retroviruses. 2006 Oct; 22(10):979-84.
27. Contreras-Galindo R, González M, Almodovar-Camacho S, González-Ramírez S, Lorenzo E, Yamamura Y. A new Real-Time-RT-PCR for quantitation of human endogenous retroviruses type K (HERV-K) RNA load in plasma samples: increased HERV-K RNA titers in HIV-1 patients with HAART non-suppressive regimens. J Virol Methods. 2006 Sep; 136(1-2):51-7.
28. Kumar R, Perez-Casanova AE, Tirado G, Noel RJ, Torres C, Rodriguez I, Martinez M, Staprans S, Kraiselburd E, Yamamura Y, Higley JD, Kumar A. Increased viral replication in simian immunodeficiency virus/simian-HIV-infected macaques with self-administering model of chronic alcohol consumption. J Acquir Immune Defic Syndr. 2005 Aug 01; 39(4):386-90.
29. Tirado G, Jove G, Reyes E, Sepulveda G, Yamamura Y, Singh DP, Kumar A. Differential evolution of cell-associated virus in blood and genital tract of HIV-infected females undergoing HAART. Virology. 2005 Apr 10; 334(2):299-305.
30. Lorenzo E, Colon MC, Almodovar S, Maldonado IM, Gonzalez S, Costa SE, Hill MD, Mendoza R, Sepulveda G, Yanagihara R, Nerurkar V, Kumar R, Yamamura Y, Scott WA, Kumar A. Influence of CD4+ T cell counts on viral evolution in HIV-infected individuals undergoing suppressive HAART. Virology. 2004 Dec 05; 330(1):116-26.
31. Kumar R, Torres C, Yamamura Y, Rodriguez I, Martinez M, Staprans S, Donahoe RM, Kraiselburd E, Stephens EB, Kumar A. Modulation by morphine of viral set point in rhesus macaques infected with simian immunodeficiency virus and simian-human immunodeficiency virus. J Virol. 2004 Oct; 78(20):11425-8.
32. Tirado G, Jove G, Kumar R, Noel RJ, Reyes E, Sepulveda G, Yamamura Y, Kumar A. Compartmentalization of drug resistance-associated mutations in a treatment-naive HIV-infected female. AIDS Res Hum Retroviruses. 2004 Jun; 20(6):684-6.
33. Carlos MP, Yamamura Y, Vu Q, Conzen K, Anderson DE, Torres JV. Humoral immunity to immunodominant epitopes of Hepatitis C virus in individuals infected with genotypes 1a or 1b. Clin Immunol. 2004 Apr; 111(1):22-7.
34. Anderson JC, Simonetti J, Fisher DG, Williams J, Yamamura Y, Rodriguez N, Sullivan DG, Gretch DR, McMahon B, Williams KJ. Comparison of different HCV viral load and genotyping assays. J Clin Virol. 2003 Sep; 28(1):27-37.

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