PROFILES - Connect with RTRN Researchers

Tarun Mandal
Title McCaffrey/Norwood Endowed Professor of Pharmacy
Faculty Rank Professor
Degree Ph.D.
Institution Xavier University of Louisiana
Department Pharmacy
Clusters Cancer
Cardiovascular and Related Diseases
HIV/AIDS
Infectious and Immunological Diseases
Address
Xavier University College of Pharmacy
1 Drexel Drive
City New Orleans
State LA
Postal Code 70125
Telephone (504) 520-7442
Fax
Email
QR Barcode

Other Positions icon

Title Adjunct Professor of Pharmaceutics
Institution University of Louisiana at Monroe
Department Pharmacy
Division "Cancer","Cancer","Cancer","Cancer","Cancer","Cardiovascular and Related Diseases","Cardiovascular and Related Diseases","Cardiovascular and Related Diseases","Cardiovascular and Related Diseases","Cardiovascular and Related Diseases","HIV/AIDS","HIV/AIDS","HIV/AIDS","HIV/AIDS","HIV/AIDS","Infectious and Immunological Diseases","Infectious and Immunological Diseases","Infectious and Immunological Diseases","Infectious and Immunological Diseases","Infectious and Immunological Diseases"
 
Title Adjunct Professor of Pharmaceutics
Institution University of Tennessee at Memthis
Department Pharmacy
Division "Pharmaceutical Sciences","Pharmaceutical Sciences","Pharmaceutical Sciences","Pharmaceutical Sciences","Pharmaceutical Sciences"
 
Title Adjunct Professor
Institution Louisiana State University Health Sciences Center
Department Genetics and Gene Therapy
Division "Pharmaceutical Sciences","Pharmaceutical Sciences","Pharmaceutical Sciences","Pharmaceutical Sciences","Pharmaceutical Sciences"
 
Title Adjunct Professor
Institution Louisiana State University Health Sciences Center
Department Microbiology, Imunology, and Parasitology
Division "Pharmaceutical Sciences","Pharmaceutical Sciences","Pharmaceutical Sciences","Pharmaceutical Sciences","Pharmaceutical Sciences"

Awards and Honors icon

2004 Xavier University of Louisiana McCaffrey/Norwood Professor of Pharmacy
2012 American Association of Pharmaceutical Sciences (AAPS) Fellow

Narrative icon

  Dr. Tarun Mandal is an Endowed Professor at Xavier University College of Pharmacy. He is also Adjunct Professor at the University of Tennessee at Memphis, University of Louisiana at Monroe, and the Louisiana State University Health Sciences Center. He is a Fellow of the American Association of Pharmaceutical Scientists. Tarun is the Director of the Center for Nanomedicine and Drug Delivery and Co-Director of the Louisiana Vaccine Center. He is a member of the Scientific Advisory Board of Autoimmune Technologies, LLC, New Orleans, LA. He is a reviewer of several study sections of NIH and DoD (US Army). He is a member of the USP Governance Committee. He is a member of the Editorial Board of (1) Clinical Medicine Reviews in Oncology; (2) Drug Development and Industrial Pharmacy; (3) Nanotechnology, Science and Applications; (4) Clinical Medicine: Oncology; (5) Journal of Biotechnology and Biomaterials; (6) Journal of Pharmacy and Pharmacology (’96-’03); (7) Pharmacy and Pharmacology Communications (’96-’03). His research interests include the development of novel pharmaceutical formulations using nanomedicine and novel drug delivery systems. During the past several years, he has been actively working on the development of numerous formulations, which include small molecules, proteins, peptides, DNA, siRNA. He has received several research grants from various state and federal agencies. He has published over 90 peer-reviewed original research papers. His research has resulted in a number of patented technologies in novel drug delivery.He received his B.S. degree in Pharmacy and M.S. and Ph.D. degrees in Pharmaceutics/Industrial Pharmacy.

Publications icon

  Check NIH Public Access Policy Compliance

Loading
Please wait
1. Graves RA, Phan KV, Bostanian LA, Mandal TK, Pramar YV. Physicochemical Stability of an Oral Suspension of Trimethoprim 20 mg/mL in Combination with Sulfadiazine 200 mg/mL in PCCA Base SuspendIt. Int J Pharm Compd. 2017 Sep-Oct; 21(5):430-435.
2. Graves R, Phan KV, Bostanian LA, Mandal TK, Pramar YV. Stability of Spironolactone Oral Suspension in PCCA Base, SuspendIt. Int J Pharm Compd. 2017 Jul-Aug; 21(4):334-338.
3. Kundu AK, Iyer SV, Chandra S, Adhikari AS, Iwakuma T, Mandal TK. Novel siRNA formulation to effectively knockdown mutant p53 in osteosarcoma. PLoS One. 2017; 12(6):e0179168.
4. Powell D, Chandra S, Dodson K, Shaheen F, Wiltz K, Ireland S, Syed M, Dash S, Wiese T, Mandal T, Kundu A. Aptamer-functionalized hybrid nanoparticle for the treatment of breast cancer. Eur J Pharm Biopharm. 2017 May; 114:108-118.
5. Ledet GA, Biswas S, Kumar VP, Graves RA, Mitchner DM, Parker TM, Bostanian LA, Ghosh SP, Mandal TK. Development of Orally Administered ?-Tocotrienol (GT3) Nanoemulsion for Radioprotection. Int J Mol Sci. 2016 Dec 24; 18(1).
6. Pramar YV, Graves RA, Ledet GA, Phan KV, Bostanian LA, Mandal TK. Stability of Clindamycin Hydrochloride in PCCA Base SuspendIt. Int J Pharm Compd. 2016 Sep-Oct; 20(5):421-425.
7. Hossain A, Tauhid L, Davenport I, Huckaba T, Graves R, Mandal T, Muniruzzaman S, Ahmed SA, Bhattacharjee PS. LRP-1 Pathway Targeted Inhibition of Vascular Abnormalities in the Retina of Diabetic Mice. Curr Eye Res. 2017 04; 42(4):640-647.
8. Hossain A, Heron D, Davenport I, Huckaba T, Graves R, Mandal T, Muniruzzaman S, Wang S, Bhattacharjee PS. Protective effects of bestatin in the retina of streptozotocin-induced diabetic mice. Exp Eye Res. 2016 08; 149:100-106.
9. Ledet G, Graves RA, Bostanian LA, Mandal TK. A second-generation inhaled insulin for diabetes mellitus. Am J Health Syst Pharm. 2015 Jul 15; 72(14):1181-7.
10. Graves RA, Ledet GA, Nation CA, Pramar YV, Bostanian LA, Mandal TK. Effect of squalane on mebendazole-loaded Compritol® nanoparticles. J Biomater Sci Polym Ed. 2015; 26(13):868-80.
11. Kumar R, Ledet G, Graves R, Datta D, Robinson S, Bansal GP, Mandal T, Kumar N. Potent Functional Immunogenicity of Plasmodium falciparum Transmission-Blocking Antigen (Pfs25) Delivered with Nanoemulsion and Porous Polymeric Nanoparticles. Pharm Res. 2015 Dec; 32(12):3827-36.
12. Graves RA, Ledet GA, Glotser EY, Mitchner DM, Bostanian LA, Mandal TK. Formulation and evaluation of biodegradable nanoparticles for the oral delivery of fenretinide. Eur J Pharm Sci. 2015 Aug 30; 76:1-9.
13. Ledet GA, Graves RA, Glotser EY, Mandal TK, Bostanian LA. Preparation and in vitro evaluation of hydrophilic fenretinide nanoparticles. Int J Pharm. 2015 Feb 20; 479(2):329-37.
14. Graves RA, Ledet G, Nation CA, Showers PR, Pramar Y, Mandal T, Bostanian LA. An ultra-high performance chromatographic method for the determination of artemisinin. Drug Dev Ind Pharm. 2015 May; 41(5):819-24.
15. Ledet G, Pamujula S, Walker V, Simon S, Graves R, Mandal TK. Development and in vitro evaluation of a nanoemulsion for transcutaneous delivery. Drug Dev Ind Pharm. 2014 Mar; 40(3):370-9.
16. Gopalakrishnan AM, Kundu AK, Mandal TK, Kumar N. Novel nanosomes for gene delivery to Plasmodium falciparum-infected red blood cells. Sci Rep. 2013; 3:1534.
17. Bhattacharjee PS, Huq TS, Potter V, Young A, Davenport IR, Graves R, Mandal TK, Clement C, McFerrin HE, Muniruzzaman S, Ireland SK, Hill JM. High-glucose-induced endothelial cell injury is inhibited by a Peptide derived from human apolipoprotein E. PLoS One. 2012; 7(12):e52152.
18. Chandra PK, Kundu AK, Hazari S, Chandra S, Bao L, Ooms T, Morris GF, Wu T, Mandal TK, Dash S. Inhibition of hepatitis C virus replication by intracellular delivery of multiple siRNAs by nanosomes. Mol Ther. 2012 Sep; 20(9):1724-36.
19. Kundu AK, Chandra PK, Hazari S, Ledet G, Pramar YV, Dash S, Mandal TK. Stability of lyophilized siRNA nanosome formulations. Int J Pharm. 2012 Feb 28; 423(2):525-34.
20. Pamujula S, Hazari S, Bolden G, Graves RA, Chinta DD, Dash S, Kishore V, Mandal TK. Cellular delivery of PEGylated PLGA nanoparticles. J Pharm Pharmacol. 2012 Jan; 64(1):61-7.
21. Kundu AK, Chandra PK, Hazari S, Pramar YV, Dash S, Mandal TK. Development and optimization of nanosomal formulations for siRNA delivery to the liver. Eur J Pharm Biopharm. 2012 Feb; 80(2):257-67.
22. Bhattacharjee PS, Huq TS, Mandal TK, Graves RA, Muniruzzaman S, Clement C, McFerrin HE, Hill JM. A novel peptide derived from human apolipoprotein E is an inhibitor of tumor growth and ocular angiogenesis. PLoS One. 2011 Jan 06; 6(1):e15905.
23. Kundu AK, Hazari S, Chinta DD, Pramar YV, Dash S, Mandal TK. Development of nanosomes using high-pressure homogenization for gene therapy. J Pharm Pharmacol. 2010 Sep; 62(9):1103-11.
24. Pamujula S, Hazari S, Bolden G, Graves RA, Chinta DM, Dash S, Kishore V, Mandal TK. Preparation and in-vitro/in-vivo evaluation of surface-modified poly (lactide-co-glycolide) fluorescent nanoparticles. J Pharm Pharmacol. 2010 Apr; 62(4):422-9.
25. Devanga-Chinta D, Graves RA, Pamujula S, Mandal TK. Controlled release multiple layer coatings. Drug Dev Ind Pharm. 2010 Feb; 36(2):200-8.
26. Chinta DD, Graves RA, Pamujula S, Praetorius N, Bostanian LA, Mandal TK. Spray-dried chitosan as a direct compression tableting excipient. Drug Dev Ind Pharm. 2009 Jan; 35(1):43-8.
27. Pamujula S, Kishore V, Rider B, Agrawal KC, Mandal TK. Radioprotection in mice following oral administration of WR-1065/PLGA nanoparticles. Int J Radiat Biol. 2008 Nov; 84(11):900-8.
28. Praetorius NP, Mandal TK. Alternate delivery route for amifostine as a radio-/chemo-protecting agent. J Pharm Pharmacol. 2008 Jul; 60(7):809-15.
29. Graves RA, Poole D, Moiseyev R, Bostanian LA, Mandal TK. Encapsulation of indomethacin using coaxial ultrasonic atomization followed by solvent evaporation. Drug Dev Ind Pharm. 2008 Apr; 34(4):419-26.
30. Pamujula S, Graves RA, Moiseyev R, Bostanian LA, Kishore V, Mandal TK. Preparation of polylactide-co-glycolide and chitosan hybrid microcapsules of amifostine using coaxial ultrasonic atomizer with solvent evaporation. J Pharm Pharmacol. 2008 Mar; 60(3):283-9.
31. Graves RA, Freeman T, Mandal TK. In vitro dissolution method for evaluation of buprenorphine in situ gel formulation: a technical note. AAPS PharmSciTech. 2007 Aug 03; 8(3):E62.
32. Praetorius NP, Mandal TK. Engineered nanoparticles in cancer therapy. Recent Pat Drug Deliv Formul. 2007; 1(1):37-51.
33. Graves RA, Freeman T, Pamajula S, Praetorius N, Moiseyev R, Mandal TK. Effect of co-solvents on the characteristics of enkephalin microcapsules. J Biomater Sci Polym Ed. 2006; 17(6):709-20.
34. Mandal TK. Inhaled insulin for diabetes mellitus. Am J Health Syst Pharm. 2005 Jul 01; 62(13):1359-64.
35. Pamujula S, Kishore V, Rider B, Fermin CD, Graves RA, Agrawal KC, Mandal TK. Radioprotection in mice following oral delivery of amifostine nanoparticles. Int J Radiat Biol. 2005 Mar; 81(3):251-7.
36. Graves RA, Moiseyev R, Freeman T, Mandal TK. Effect of surfactant on the characteristics of biodegradable microcapsules. J Biomater Sci Polym Ed. 2005; 16(5):585-96.
37. Pamujula S, Graves RA, Freeman T, Srinivasan V, Bostanian LA, Kishore V, Mandal TK. Oral delivery of spray dried PLGA/amifostine nanoparticles. J Pharm Pharmacol. 2004 Sep; 56(9):1119-25.
38. Pamujula S, Graves RA, Kishore V, Mandal TK. Preparation and in vitro characterization of amifostine biodegradable microcapsules. Eur J Pharm Biopharm. 2004 Mar; 57(2):213-8.
39. Graves RA, Pamujula S, Moiseyev R, Freeman T, Bostanian LA, Mandal TK. Effect of different ratios of high and low molecular weight PLGA blend on the characteristics of pentamidine microcapsules. Int J Pharm. 2004 Feb 11; 270(1-2):251-62.
40. Mandal TK, Bostanian LA, Graves RA, Chapman SR. Poly(D,L-lactide-co-glycolide) encapsulated poly(vinyl alcohol) hydrogel as a drug delivery system. Pharm Res. 2002 Nov; 19(11):1713-9.
41. Mandal TK, Bostanian LA, Graves RA, Chapman SR, Womack I. Development of biodegradable microcapsules as carrier for oral controlled delivery of amifostine. Drug Dev Ind Pharm. 2002 Mar; 28(3):339-44.
42. Mandal TK, Bostanian LA, Graves RA, Chapman SR, Idodo TU. Porous biodegradable microparticles for delivery of pentamidine. Eur J Pharm Biopharm. 2001 Jul; 52(1):91-6.
43. Mandal TK. Swelling-controlled release system for the vaginal delivery of miconazole. Eur J Pharm Biopharm. 2000 Nov; 50(3):337-43.
44. Mandal TK. American Association of Pharmaceutical Scientists--annual meeting and exposition. 14-18 November 1999, New Orleans, LA, USA. IDrugs. 2000 Feb; 3(2):147.
45. Mandal TK, Bostanian LA. Effect of peptide loading and surfactant concentration on the characteristics of physically crosslinked hydrogel. Pharm Dev Technol. 2000; 5(4):555-60.
46. Mandal TK. Development of biodegradable drug delivery system to treat addiction. Drug Dev Ind Pharm. 1999 Jun; 25(6):773-9.
47. Mandal TK. American College of Cardiology--48th annual scientific session. 7-10 March 1999, New Orleans, LA, USA. IDrugs. 1999 May; 2(5):393.
48. Mandal TK. Effect of solvent on the characteristics of pentamidine loaded microcapsule. J Biomater Sci Polym Ed. 1999; 10(1):1-17.
49. Mandal TK. Evaluation of a novel phase separation technique for the encapsulation of water-soluble drugs in biodegradable polymer. Drug Dev Ind Pharm. 1998 Jul; 24(7):623-9.
50. Mandal TK, Shekleton M, Onyebueke E, Washington L, Penson T. Effect of formulation and processing factors on the characteristics of biodegradable microcapsules of zidovudine. J Microencapsul. 1996 Sep-Oct; 13(5):545-57.
51. Mandal TK. Effect of tablet integrity on the dissolution rate of sustained-release preparations. J Clin Pharm Ther. 1996 Jun; 21(3):155-7.
52. Mandal TK, Lopez-Anaya A, Onyebueke E, Shekleton M. Preparation of biodegradable microcapsules containing zidovudine (AZT) using solvent evaporation technique. J Microencapsul. 1996 May-Jun; 13(3):257-67.
53. Mandal TK, Ace LN. High-performance liquid chromatographic determination of perphenazine in plasma. J Clin Pharm Ther. 1993 Jun; 18(3):205-8.

Research Resources icon

Funding Opportunities icon

Browse active NIH & NSF funding opportunities, requests for applications (RFAs), and program announcements (PAs)

Publications Timeline

Top MeSH Keywords

Tree Map of Keyword Semantic Groups (Categories)

Left-click a node to move down the tree, right-click the graph to move back up the tree

Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile:
 
Keyword
Last Name
Institution
 
Keywords
Nanoparticles
Lactic Acid
Polyglycolic Acid
Drug Carriers
Drug Delivery Systems
See all (269) keywords
See all (10) people See all (36) people Search for (3) people
Feedback

RTRN Collaboration and Professional Networking Feedback