PROFILES - Connect with RTRN Researchers

Marla J. Berry
Title Professor and Chair
Faculty Rank Professor
Degree Ph.D.
Institution University of Hawaii
Department Department of Cell and Molecular Biology
Clusters Neurological Disorders and Mental Health
Obesity and Metabolic Syndromes
Address
John A. Burns School of Medicine
651 Ilalo Street
City Honolulu
State HI
Postal Code 96813
Telephone 808-692-1506
Fax
Email
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Other Positions icon

Title Graduate Faculty
Institution University of Hawaii
Department CTAHR
Division Human Nutrition

Awards and Honors icon

1993 Endocrine Society Women in Endocrinology Award
1998 University of Missouri, Columbia Nutrition Emphasis Week Visiting Professor
1999 American Thyroid Association Van Meter Prize for outstanding contributions to thyroid research
2001 Pennsylvania State Univ. Ruth Pike Lectureship for significant contributions to nutrition research
2004 University of Maryland Mary Shorb Lecturer
2006 Scientist of the Year, Achievement Rewards for College Scientists, Honolulu Chapter

Narrative icon

  My scientific background includes three decades of experience in biochemistry and cell and molecular biology utilizing cell culture and animal models of human disease, and over two decades studying the functions of antioxidant selenoenzymes in health and disease. During my postdoctoral studies, I was first author on two publications in Nature. The seminal findings described in these publications led to my first NIH R01 grant, an appointment as Assistant Professor at Harvard Medical School, and issue of a US Patent. I remained on the faculty at Harvard Med for 11 years, where I obtained two additional NIH R01s and was promoted to Associate Professor. In 2002, I was recruited by the University of Hawaii, where I was tenured as a full Professor the following year. I have been continuously funded by the NIH since 1993, serving as PI on two R01s beginning in 1997 and three R01s during the period from 2000 to 2007. I served as a Charter Member of the NIH Nutrition Study Section and the Integrative Nutrition and Metabolic Processes Study Section from 2001 through 2005, as well as ad hoc on numerous study sections since 1993. Research in my laboratory currently includes mouse models with alterations in selenium metabolism, affecting antioxidant enzyme expression and resulting in metabolic syndrome and impaired neurological function. We are also investigating epigenetic changes in preeclampsia and have identified hypermethylation and hypomethylation in genes associated with cardiovascular disease-related processes.

Mentorship icon

 
Availability Date:
Friday, February 23, 2018

I have served as Cell and Molecular Biology Department Chair and as Co-chair of the Cell and Molecular Biology Graduate Program at the University of Hawaii since 2004. As a faculty member, I have mentored 41 graduate students (14 minority), 18 postdoctoral fellows, 6 M.D. research fellows, 33 undergraduates (17 minority), and 14 high school students (9 minority). I have served on 44 dissertation or thesis committees, chairing 13 PhD dissertation committees and 3 Master’s thesis committees. Current positions of my former trainees include tenure-track or tenured faculty at Harvard Medical School, the University of Pennsylvania, Mount Sinai School of Medicine, North Carolina Central University, and the University of Hawaii, the Chief Scientific Officer of a biotechnology company in Southern California, and a patent attorney at a biotechnology development company in Auckland, New Zealand. Recent PhD graduates from my laboratory are now postdoctoral researchers at the Institute for Systems Biology in Seattle and at Harvard Medical School, an Assistant Professor in the School of Biological and Physical Sciences at Daytona State College, FL, an MD-PhD student at the University of Pennsylvania, and a resident in family medicine in Syracuse, NY. Among faculty that I have mentored or am currently mentoring, 8 have been awarded R01 grants, 5 have obtained R21 grants, and 7 have been tenured. At present, I consider mentoring and training researchers at all levels as the most important contribution I can make to the University of Hawaii and the scientific community as a whole.

I am available to mentor as:
Mentoring junior faculty, postdocs and graduate students in professional development, and scientifically in research related to my expertise in cell and molecular biology and animal models of human disease.

Contact Information for Mentoring:
mberry@hawaii.edu

Online Resources icon

Programs, Membership, and Biomedical Research icon

Mentoring Mentor
BIOMEDICAL RESEARCH BIOMEDICAL - BASIC
BIOMEDICAL - BASIC CELL BIOLOGY
BIOMEDICAL - BASIC BIOCHEMISTRY
BIOMEDICAL - BASIC MOLECULAR BIOLOGY

NIH Awarded Grants icon

  Research projects funded by the National Institutes of Health (NIH), the Centers for Disease Control (CDC), the Food and Drug Administration (FDA), and the Department of Veterans Affairs (VA)

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1.
2018Mechanism of Selenoprotein Synthesis3R01DK047320-22S1
2.
2018Mechanism of Selenoprotein Synthesis5R01DK047320-22
3.
2017Investigator Development Core2U54MD007601-31
4.
2017Mechanism of Selenoprotein Synthesis2R01DK047320-21A1
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2016Bioscience Research Infrastructure Development for Grant Enhancement and Success3G12MD007601-30S1
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2015MR IMAGING CORE5G12MD007601-30
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2015RESEARCH DESIGN, BIOSTATISTICS AND RESEARCH ETHICS CORE5G12MD007601-30
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2015Bioscience Research Infrastructure Development for Grant Enhancement and Success5G12MD007601-30
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2015HISTOPATHOLOGY CORE5G12MD007601-30
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2015MICROSCOPY CORE5G12MD007601-30
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2015EVALUATION CORE5G12MD007601-30
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2015BIOMEDICAL INFORMATICS CORE5G12MD007601-30
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2015BEHAVIORAL-ELECTROPHYSCIOLOGY MURINE PHENOTYPING CORE5G12MD007601-30
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2015PILOT PROJECT CORE5G12MD007601-30
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2015ADMIN CORE5G12MD007601-30
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2015PROTEOMICS CORE5G12MD007601-30
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2015Mechanism of Selenoprotein Synthesis5R01DK047320-20
18.
2015HUMAN TISSUE BIOREPOSITORY5G12MD007601-30
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2014Mechanism of Selenoprotein Synthesis3R01DK047320-19S1
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2014Bioscience Research Infrastructure Development for Grant Enhancement and Success5G12MD007601-29
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2014Mechanism of Selenoprotein Synthesis3R01DK047320-19S2
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2014Mechanism of Selenoprotein Synthesis5R01DK047320-19
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2013Bioscience Research Infrastructure Development for Grant Enhancement and Success5G12MD007601-28
24.
2013Mechanism of Selenoprotein Synthesis5R01DK047320-18
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2012Mechanism of Selenoprotein Synthesis5R01DK047320-17
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2012Bioscience Research Infrastructure Development for Grant Enhancement and Success8G12MD007601-27
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2011Bioscience Research Infrastructure Development for Grant Enhancement and Success2G12RR003061-26
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2011Mechanism of Selenoprotein Synthesis2R01DK047320-16A2
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2011ACTIVITY 2: BIOACTIVE NUTRIENTS CORE2G12RR003061-26
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2010ACTIVITY 2: BIOACTIVE NUTRIENTS CORE5G12RR003061-25
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2009ACTIVITY 2: BIOACTIVE NUTRIENTS CORE5G12RR003061-24
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2009MECHANISM OF SELENOPROTEIN SYNTHESIS2R56DK047320-16
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2008ACTIVITY 2: BIOACTIVE NUTRIENTS CORE5G12RR003061-23
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2008Mechanism of selenoprotein synthesis5R01DK047320-15
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2007Mechanism of selenoprotein synthesis5R01DK047320-14
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2007Selenoprotein P function and regulation of expression5R01NS040302-09
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2007ACTIVITY 2: BIOACTIVE NUTRIENTS CORE5G12RR003061-22
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2006Selenoprotein P function and regulation of expression5R01NS040302-08
39.
2006Mechanism of selenoprotein synthesis5R01DK047320-13
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2005Mechanism of selenoprotein synthesis5R01DK047320-12
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2005Selenoprotein P function and regulation of expression5R01NS040302-07
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2005ALTERNATIVE MECHANISMS OF UGA CODON RECOGNITION5R01DK052963-10
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2004Mechanism of selenoprotein synthesis2R01DK047320-11
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2004Selenoprotein P function and regulation of expression2R01NS040302-06
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2004ALTERNATIVE MECHANISMS OF UGA CODON RECOGNITION5R01DK052963-09
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2003ALTERNATIVE MECHANISMS OF UGA CODON RECOGNITION5R01DK052963-08
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2003SELENOPROTEIN P FUNCTION AND REGULATION OF EXPRESSION5R01NS040302-05
48.
2002MECHANISM OF SELENOPROTEIN SYNTHESIS IN EUKARYOTES5R01DK047320-10
49.
2002SELENOPROTEIN P FUNCTION AND REGULATION OF EXPRESSION7R01NS040302-04
50.
2002ALTERNATIVE MECHANISMS OF UGA CODON RECOGNITION5R01DK052963-07
51.
2001SELENOPROTEIN P FUNCTION AND REGULATION OF EXPRESSION5R01NS040302-02
52.
2001MECHANISM OF SELENOPROTEIN SYNTHESIS IN EUKARYOTES7R01DK047320-09
53.
2001ALTERNATIVE MECHANISMS OF UGA CODON RECOGNITION2R01DK052963-05
54.
2001MECHANISM OF SELENOPROTEIN SYNTHESIS IN EUKARYOTES5R01DK047320-08
55.
2001ALTERNATIVE MECHANISMS OF UGA CODON RECOGNITION7R01DK052963-06
56.
2000ALTERNATIVE MECHANISMS OF UGA CODON RECOGNITION5R01DK052963-04
57.
2000MECHANISM OF SELENOPROTEIN SYNTHESIS IN EUKARYOTES5R01DK047320-07
58.
2000SELENOPROTEIN P FUNCTION AND REGULATION OF EXPRESSION1R01NS040302-01
59.
1999MECHANISM OF SELENOPROTEIN SYNTHESIS IN EUKARYOTES3R01DK047320-06S1