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pankaj sharma
Title dr
Faculty Rank research scientist
Degree phd
Institution Morehouse School of Medicine
Department neuroscience
Clusters Cancer
Neurological Disorders and Mental Health
Address
1368 Vernon North Drive
City Atlanta
State GA
Postal Code 30338
Telephone 5103666072
Fax
Email
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1. Hernandez-Encarnacion L, Sharma P, Simon R, Zhou A. Condition-specific transcriptional regulation of neuronal ion channel genes in brain ischemia. Int J Physiol Pathophysiol Pharmacol. 2017; 9(6):192-201.
2. Khurana N, Kim H, Chandra PK, Talwar S, Sharma P, Abdel-Mageed AB, Sikka SC, Mondal D. Multimodal actions of the phytochemical sulforaphane suppress both AR and AR-V7 in 22Rv1 cells: Advocating a potent pharmaceutical combination against castration-resistant prostate cancer. Oncol Rep. 2017 Nov; 38(5):2774-2786.
3. Joshi JB, Patel D, Morton DJ, Sharma P, Zou J, Hewa Bostanthirige D, Gorantla Y, Nagappan P, Komaragiri SK, Sivils JC, Xie H, Palaniappan R, Wang G, Cox MB, Chaudhary J. Inactivation of ID4 promotes a CRPC phenotype with constitutive AR activation through FKBP52. Mol Oncol. 2017 04; 11(4):337-357.
4. Korang-Yeboah M, Patel D, Morton D, Sharma P, Gorantla Y, Joshi J, Nagappan P, Pallaniappan R, Chaudhary J. Intra-tumoral delivery of functional ID4 protein via PCL/maltodextrin nano-particle inhibits prostate cancer growth. Oncotarget. 2016 Oct 18; 7(42):68072-68085.
5. Khurana N, Talwar S, Chandra PK, Sharma P, Abdel-Mageed AB, Mondal D, Sikka SC. Sulforaphane increases the efficacy of anti-androgens by rapidly decreasing androgen receptor levels in prostate cancer cells. Int J Oncol. 2016 Oct; 49(4):1609-19.
6. Senwar KR, Reddy TS, Thummuri D, Sharma P, Naidu VG, Srinivasulu G, Shankaraiah N. Design, synthesis and apoptosis inducing effect of novel (Z)-3-(3'-methoxy-4'-(2-amino-2-oxoethoxy)-benzylidene)indolin-2-ones as potential antitumour agents. Eur J Med Chem. 2016 Aug 08; 118:34-46.
7. Korang-Yeboah M, Gorantla Y, Paulos SA, Sharma P, Chaudhary J, Palaniappan R. Polycaprolactone/maltodextrin nanocarrier for intracellular drug delivery: formulation, uptake mechanism, internalization kinetics, and subcellular localization. Int J Nanomedicine. 2015; 10:4763-81.
8. Sharma P, Chinaranagari S, Chaudhary J. Inhibitor of differentiation 4 (ID4) acts as an inhibitor of ID-1, -2 and -3 and promotes basic helix loop helix (bHLH) E47 DNA binding and transcriptional activity. Biochimie. 2015 May; 112:139-50.
9. Chinaranagari S, Sharma P, Bowen NJ, Chaudhary J. Prostate cancer epigenome. Methods Mol Biol. 2015; 1238:125-40.
10. Verma M. Cancer epigenetics: risk assessment, diagnosis, treatment, and prognosis. Preface. Methods Mol Biol. 2015; 1238:v-vi.
11. Chinaranagari S, Sharma P, Chaudhary J. EZH2 dependent H3K27me3 is involved in epigenetic silencing of ID4 in prostate cancer. Oncotarget. 2014 Aug 30; 5(16):7172-82.
12. Patel D, Knowell AE, Korang-Yeboah M, Sharma P, Joshi J, Glymph S, Chinaranagari S, Nagappan P, Palaniappan R, Bowen NJ, Chaudhary J. Inhibitor of differentiation 4 (ID4) inactivation promotes de novo steroidogenesis and castration-resistant prostate cancer. Mol Endocrinol. 2014 Aug; 28(8):1239-53.
13. Knowell AE, Patel D, Morton DJ, Sharma P, Glymph S, Chaudhary J. Id4 dependent acetylation restores mutant-p53 transcriptional activity. Mol Cancer. 2013 Dec 13; 12:161.
14. Sharma P, Knowell AE, Chinaranagari S, Komaragiri S, Nagappan P, Patel D, Havrda MC, Chaudhary J. Id4 deficiency attenuates prostate development and promotes PIN-like lesions by regulating androgen receptor activity and expression of NKX3.1 and PTEN. Mol Cancer. 2013 Jun 21; 12:67.
15. Sharma P, Patel D, Chaudhary J. Id1 and Id3 expression is associated with increasing grade of prostate cancer: Id3 preferentially regulates CDKN1B. Cancer Med. 2012 Oct; 1(2):187-97.
16. Sharma P, Chinaranagari S, Patel D, Carey J, Chaudhary J. Epigenetic inactivation of inhibitor of differentiation 4 (Id4) correlates with prostate cancer. Cancer Med. 2012 Oct; 1(2):176-86.
17. Panicker SP, Raychaudhuri B, Sharma P, Tipps R, Mazumdar T, Mal AK, Palomo JM, Vogelbaum MA, Haque SJ. p300- and Myc-mediated regulation of glioblastoma multiforme cell differentiation. Oncotarget. 2010 Aug; 1(4):289-303.
18. Rahaman SO, Sharma P, Harbor PC, Aman MJ, Vogelbaum MA, Haque SJ. IL-13R(alpha)2, a decoy receptor for IL-13 acts as an inhibitor of IL-4-dependent signal transduction in glioblastoma cells. Cancer Res. 2002 Feb 15; 62(4):1103-9.

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1. Sharma P and Vasudeva M . journal of plant interaction. Effect of azide resistant mutants of Azospirillum brasilense and Acetobacter diazotrophicus on yield and nitrogen content in cotton (Gossypium hirsutum and Gossypium herbaceum). 2012; 2(1):206-216.
2. Sharma P and Yadav A . Euro. J. Exp. Bio. Symbiotic characterization of mutants defective in proline dehydrogenase in Rhizobium sp. Cajanus under drought stress condition. 2012; 2(1):206-216.
3. 12 Sharma P, Vasudeva M, Kharb P, Lakshminarayana K, Vashishat RK . Archives of Agronomy and Soil Science. Effect of azide resistant mutants of Azotobacter chroococcum on yield and nitrogen content in two cotton genotypes. 2002; 48(6):585-591.

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