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J. Tyson McDonald
Title Research Associate
Faculty Rank Adjunct Faculty
Degree PhD
Institution Hampton University
Department Cancer Research Center
Clusters Cancer
Women's Health and Reproductive Biology
27 E. Tyler Street
F. Fountain Building, Room 200
City Hampton
State VA
Postal Code 23668
Telephone 757-728-6080
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Awards and Honors icon

1999 George Bird Grinnell American Indian Fund American Indian Children’s Scholarship
1999 Te-Moak Band of Western Shoshone Higher Education Scholarship
2003 National Academy for Nuclear Training Scholarship
2004 University of Michigan’s College of Engineering Distinguished Leadership Award
2005 NIH-NIEHS Association of American Indian Physicians Award
2008 AACR Minority in Cancer Research Scholars Award
2008 Radiation Research Society Scholars Award
2010 Brookhaven National Laboratories Department of Energy
2011 Department of Energy Low Dose Investigator Workshop Travel Award
2015 AACR Minority in Cancer Research Scholars Award

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1. Ricks-Santi LJ, McDonald JT. Low utility of Oncotype DX® in the clinic. Cancer Med. 2017 Mar; 6(3):501-507.
2. Beheshti A, Vanderburg C, McDonald JT, Ramkumar C, Kadungure T, Zhang H, Gartenhaus RB, Evens AM. A Circulating microRNA Signature Predicts Age-Based Development of Lymphoma. PLoS One. 2017; 12(1):e0170521.
3. McDonald JE, Kessler MM, Gardner MW, Buros AF, Ntambi JA, Waheed S, van Rhee F, Zangari M, Heuck CJ, Petty N, Schinke C, Thanendrarajan S, Mitchell A, Hoering A, Barlogie B, Morgan GJ, Davies FE. Assessment of Total Lesion Glycolysis by 18F FDG PET/CT Significantly Improves Prognostic Value of GEP and ISS in Myeloma. Clin Cancer Res. 2017 04 15; 23(8):1981-1987.
4. Beheshti A, Neuberg D, McDonald JT, Vanderburg CR, Evens AM. The Impact of Age and Sex in DLBCL: Systems Biology Analyses Identify Distinct Molecular Changes and Signaling Networks. Cancer Inform. 2015; 14:141-8.
5. Beheshti A, Wage J, McDonald JT, Lamont C, Peluso M, Hahnfeldt P, Hlatky L. Tumor-host signaling interaction reveals a systemic, age-dependent splenic immune influence on tumor development. Oncotarget. 2015 Nov 03; 6(34):35419-32.
6. Beheshti A, Benzekry S, McDonald JT, Ma L, Peluso M, Hahnfeldt P, Hlatky L. Host age is a systemic regulator of gene expression impacting cancer progression. Cancer Res. 2015 Mar 15; 75(6):1134-43.
7. Gao X, McDonald JT, Naidu M, Hahnfeldt P, Hlatky L. A proposed quantitative index for assessing the potential contribution of reprogramming to cancer stem cell kinetics. Stem Cells Int. 2014; 2014:249309.
8. Sasi SP, Song J, Park D, Enderling H, McDonald JT, Gee H, Garrity B, Shtifman A, Yan X, Walsh K, Natarajan M, Kishore R, Goukassian DA. TNF-TNFR2/p75 signaling inhibits early and increases delayed nontargeted effects in bone marrow-derived endothelial progenitor cells. J Biol Chem. 2014 May 16; 289(20):14178-93.
9. McDonald JT, Briggs C, Szelag H, Peluso M, Schneider D, Perepletchikov A, Klement GL, Tuerk I, Hlatky L. Chronic low dose-rate radiation down-regulates transcription related to mitosis and chromosomal movement similar to acute high dose in prostate cells. Int J Radiat Biol. 2014 Mar; 90(3):231-40.
10. Beheshti A, Pinzer BR, McDonald JT, Stampanoni M, Hlatky L. Early tumor development captured through nondestructive, high resolution differential phase contrast X-ray imaging. Radiat Res. 2013 Nov; 180(5):448-54.
11. Gao X, McDonald JT, Hlatky L, Enderling H. Acute and fractionated irradiation differentially modulate glioma stem cell division kinetics. Cancer Res. 2013 Mar 01; 73(5):1481-90.
12. McDonald JT, Kim K, Norris AJ, Vlashi E, Phillips TM, Lagadec C, Della Donna L, Ratikan J, Szelag H, Hlatky L, McBride WH. Ionizing radiation activates the Nrf2 antioxidant response. Cancer Res. 2010 Nov 01; 70(21):8886-95.
13. Kim K, Pollard JM, Norris AJ, McDonald JT, Sun Y, Micewicz E, Pettijohn K, Damoiseaux R, Iwamoto KS, Sayre JW, Price BD, Gatti RA, McBride WH. High-throughput screening identifies two classes of antibiotics as radioprotectors: tetracyclines and fluoroquinolones. Clin Cancer Res. 2009 Dec 01; 15(23):7238-45.
14. Vlashi E, Kim K, Lagadec C, Donna LD, McDonald JT, Eghbali M, Sayre JW, Stefani E, McBride W, Pajonk F. In vivo imaging, tracking, and targeting of cancer stem cells. J Natl Cancer Inst. 2009 Mar 04; 101(5):350-9.
15. Pursell ZF, McDonald JT, Mathews CK, Kunkel TA. Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase gamma replication fidelity. Nucleic Acids Res. 2008 Apr; 36(7):2174-81.
16. McDonald JT, West WG, Kearfott KJ. An evaluation of the Kearny Fallout Meter (KFM), a radiation detector constructed from commonly available household materials. Health Phys. 2004 Nov; 87(5 Suppl):S52-7.

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