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Michele Carbone, MD, PhD.

Title
Faculty RankProfessor
InstitutionUniversity of Hawaii
DepartmentCancer Biology
AddressUniversity of Hawaii Cancer Center
701 Ilalo Street
Honolulu HI 96816
Phone8084404596
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    Collapse Research 
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    P30CA071789     (HOLCOMBE, RANDALL F)Jul 8, 1996 - Jun 30, 2023
    NIH
    University of Hawaii Cancer Center CCSG
    Role: Co-Principal Investigator
    R29CA077220     (CARBONE, MICHELE)Aug 1, 1997 - Jul 31, 2003
    NIH
    SV40-LIKE SEQUENCES IN HUMAN TUMORS ANALYSES
    Role: Principal Investigator
    R01CA092657     (CARBONE, MICHELE)Apr 1, 2002 - Mar 31, 2009
    NIH
    SV40 sequences in human tumors: analysis &biologic*
    Role: Principal Investigator
    R01CA106567     (CARBONE, MICHELE)Mar 8, 2005 - Jan 31, 2011
    NIH
    Role of Cell Mediators in Asbestos-SV40 Carcinogenesis
    Role: Principal Investigator
    P01CA114047     (CARBONE, MICHELE)Sep 15, 2006 - Aug 31, 2013
    NIH
    Pathogenesis of mesothelioma
    Role: Principal Investigator
    R01CA198138     (CARBONE, MICHELE)Jul 6, 2015 - Jun 30, 2021
    NIH
    Germline BAP1 Mutations and Malignant Mesothelioma: Mechanisms and Early Detection
    Role: Principal Investigator
    R01ES030948     (CARBONE, MICHELE)Aug 15, 2019 - Jun 30, 2022
    NIH
    Influence of germline mutations on susceptibility to environmental carcinogens
    Role: Principal Investigator
    R01CA237235     (CARBONE, MICHELE)Dec 13, 2019 - Nov 30, 2024
    NIH
    Mechanisms of BAP1 activity in human cancer development
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Carbone M, Minaai M, Takinishi Y, Pagano I, Yang H. Preventive and therapeutic opportunities: targeting BAP1 and/or HMGB1 pathways to diminish the burden of mesothelioma. J Transl Med. 2023 10 25; 21(1):749. PMID: 37880686.
      Citations:    Fields:    Translation:Humans
    2. Suarez JS, Novelli F, Goto K, Ehara M, Steele M, Kim JH, Zolondick AA, Xue J, Xu R, Saito M, Pastorino S, Minaai M, Takanishi Y, Emi M, Pagano I, Wakeham A, Berger T, Pass HI, Gaudino G, Mak TW, Carbone M, Yang H. HMGB1 released by mesothelial cells drives the development of asbestos-induced mesothelioma. Proc Natl Acad Sci U S A. 2023 09 26; 120(39):e2307999120. PMID: 37729199.
      Citations:    Fields:    Translation:Animals
    3. Carbone M, Yang H, Pass HI, Taioli E. Did the Ban on Asbestos Reduce the Incidence of Mesothelioma? J Thorac Oncol. 2023 06; 18(6):694-697. PMID: 37210180.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    4. Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, Balachandran S, Bano D, Barlev NA, Bartek J, Bazan NG, Becker C, Bernassola F, Bertrand MJM, Bianchi ME, Blagosklonny MV, Blander JM, Blandino G, Blomgren K, Borner C, Bortner CD, Bove P, Boya P, Brenner C, Broz P, Brunner T, Damgaard RB, Calin GA, Campanella M, Candi E, Carbone M, Carmona-Gutierrez D, Cecconi F, Chan FK, Chen GQ, Chen Q, Chen YH, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Ciliberto G, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Daugaard M, Dawson TM, Dawson VL, De Maria R, De Strooper B, Debatin KM, Deberardinis RJ, Degterev A, Del Sal G, Deshmukh M, Di Virgilio F, Diederich M, Dixon SJ, Dynlacht BD, El-Deiry WS, Elrod JW, Engeland K, Fimia GM, Galassi C, Ganini C, Garcia-Saez AJ, Garg AD, Garrido C, Gavathiotis E, Gerlic M, Ghosh S, Green DR, Greene LA, Gronemeyer H, H?cker G, Hajn?czky G, Hardwick JM, Haupt Y, He S, Heery DM, Hengartner MO, Hetz C, Hildeman DA, Ichijo H, Inoue S, J??ttel? M, Janic A, Joseph B, Jost PJ, Kanneganti TD, Karin M, Kashkar H, Kaufmann T, Kelly GL, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Kluck R, Krysko DV, Kulms D, Kumar S, Lavandero S, Lavrik IN, Lemasters JJ, Liccardi G, Linkermann A, Lipton SA, Lockshin RA, L?pez-Ot?n C, Luedde T, MacFarlane M, Madeo F, Malorni W, Manic G, Mantovani R, Marchi S, Marine JC, Martin SJ, Martinou JC, Mastroberardino PG, Medema JP, Mehlen P, Meier P, Melino G, Melino S, Miao EA, Moll UM, Mu?oz-Pinedo C, Murphy DJ, Niklison-Chirou MV, Novelli F, N??ez G, Oberst A, Ofengeim D, Opferman JT, Oren M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pentimalli F, Pereira DM, Pervaiz S, Peter ME, Pinton P, Porta G, Prehn JHM, Puthalakath H, Rabinovich GA, Rajalingam K, Ravichandran KS, Rehm M, Ricci JE, Rizzuto R, Robinson N, Rodrigues CMP, Rotblat B, Rothlin CV, Rubinsztein DC, Rudel T, Rufini A, Ryan KM, Sarosiek KA, Sawa A, Sayan E, Schroder K, Scorrano L, Sesti F, Shao F, Shi Y, Sica GS, Silke J, Simon HU, Sistigu A, Stephanou A, Stockwell BR, Strapazzon F, Strasser A, Sun L, Sun E, Sun Q, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Troy CM, Turk B, Urbano N, Vandenabeele P, Vanden Berghe T, Vander Heiden MG, Vanderluit JL, Verkhratsky A, Villunger A, von Karstedt S, Voss AK, Vousden KH, Vucic D, Vuri D, Wagner EF, Walczak H, Wallach D, Wang R, Wang Y, Weber A, Wood W, Yamazaki T, Yang HT, Zakeri Z, Zawacka-Pankau JE, Zhang L, Zhang H, Zhivotovsky B, Zhou W, Piacentini M, Kroemer G, Galluzzi L. Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death Differ. 2023 05; 30(5):1097-1154. PMID: 37100955.
      Citations: 31     Fields:    Translation:HumansAnimals
    5. Saftner DM, Bacon SN, Arienzo MM, Robtoy E, Schlauch K, Neveux I, Grzymski JJ, Carbone M. Predictions of Arsenic in Domestic Well Water Sourced from Alluvial Aquifers of the Western Great Basin, USA. Environ Sci Technol. 2023 02 28; 57(8):3124-3133. PMID: 36795051.
      Citations:    Fields:    Translation:PHPublic Health
    6. Bononi A, Wang Q, Zolondick AA, Bai F, Steele-Tanji M, Suarez JS, Pastorino S, Sipes A, Signorato V, Ferro A, Novelli F, Kim JH, Minaai M, Takinishi Y, Pellegrini L, Napolitano A, Xu R, Farrar C, Goparaju C, Bassi C, Negrini M, Pagano I, Sakamoto G, Gaudino G, Pass HI, Onuchic JN, Yang H, Carbone M. BAP1 is a novel regulator of HIF-1a. Proc Natl Acad Sci U S A. 2023 01 24; 120(4):e2217840120. PMID: 36656861.
      Citations: 1     Fields:    Translation:Humans
    7. Arienzo MM, Saftner D, Bacon SN, Robtoy E, Neveux I, Schlauch K, Carbone M, Grzymski J. Naturally occurring metals in unregulated domestic wells in Nevada, USA. Sci Total Environ. 2022 Dec 10; 851(Pt 2):158277. PMID: 36029812.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    8. Yang H, Gaudino G, Bardelli F, Carbone M. Does the Amount of Asbestos Exposure Influence Prognosis? J Thorac Oncol. 2022 08; 17(8):949-952. PMID: 35931423.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    9. Vitto VAM, Bianchin S, Zolondick AA, Pellielo G, Rimessi A, Chianese D, Yang H, Carbone M, Pinton P, Giorgi C, Patergnani S. Molecular Mechanisms of Autophagy in Cancer Development, Progression, and Therapy. Biomedicines. 2022 Jul 05; 10(7). PMID: 35884904.
      Citations:    
    10. Carbone M, Pass HI, Ak G, Alexander HR, Baas P, Baumann F, Blakely AM, Bueno R, Bzura A, Cardillo G, Churpek JE, Dianzani I, De Rienzo A, Emi M, Emri S, Felley-Bosco E, Fennell DA, Flores RM, Grosso F, Hayward NK, Hesdorffer M, Hoang CD, Johansson PA, Kindler HL, Kittaneh M, Krausz T, Mansfield A, Metintas M, Minaai M, Mutti L, Nielsen M, O'Byrne K, Opitz I, Pastorino S, Pentimalli F, de Perrot M, Pritchard A, Ripley RT, Robinson B, Rusch V, Taioli E, Takinishi Y, Tanji M, Tsao AS, Tuncer AM, Walpole S, Wolf A, Yang H, Yoshikawa Y, Zolondick A, Schrump DS, Hassan R. Medical and Surgical Care of Patients With Mesothelioma and Their Relatives Carrying Germline BAP1 Mutations. J Thorac Oncol. 2022 07; 17(7):873-889. PMID: 35462085.
      Citations: 24     Fields:    Translation:Humans
    11. Novelli F, Bononi A, Wang Q, Bai F, Patergnani S, Kricek F, Haglund E, Suarez JS, Tanji M, Xu R, Takanishi Y, Minaai M, Pastorino S, Morris P, Sakamoto G, Pass HI, Barbour H, Gaudino G, Giorgi C, Pinton P, Onuchic JN, Yang H, Carbone M. BAP1 forms a trimer with HMGB1 and HDAC1 that modulates gene ? environment interaction with asbestos. Proc Natl Acad Sci U S A. 2021 11 30; 118(48). PMID: 34815344.
      Citations: 8     Fields:    Translation:AnimalsCells
    12. Zolondick AA, Gaudino G, Xue J, Pass HI, Carbone M, Yang H. Asbestos-induced chronic inflammation in malignant pleural mesothelioma and related therapeutic approaches-a narrative review. Precis Cancer Med. 2021 Sep; 4. PMID: 35098108.
      Citations:    
    13. Zhang L, Vunnamadala SP, Yagi S, Meraj R, Carbone M. Delayed positive COVID19 nasopharyngeal test, a case study with clinical and pathological correlation. BMC Pulm Med. 2021 Aug 31; 21(1):278. PMID: 34465321.
      Citations:    Fields:    Translation:HumansCells
    14. Carbone M, Lednicky J, Xiao SY, Venditti M, Bucci E. Coronavirus 2019 Infectious Disease Epidemic: Where We Are, What Can Be Done and Hope For. J Thorac Oncol. 2021 04; 16(4):546-571. PMID: 33422679.
      Citations: 13     Fields:    Translation:HumansCells
    15. Bononi A, Goto K, Ak G, Yoshikawa Y, Emi M, Pastorino S, Carparelli L, Ferro A, Nasu M, Kim JH, Suarez JS, Xu R, Tanji M, Takinishi Y, Minaai M, Novelli F, Pagano I, Gaudino G, Pass HI, Groden J, Grzymski JJ, Metintas M, Akarsu M, Morrow B, Hassan R, Yang H, Carbone M. Heterozygous germline BLM mutations increase susceptibility to asbestos and mesothelioma. Proc Natl Acad Sci U S A. 2020 12 29; 117(52):33466-33473. PMID: 33318203.
      Citations: 14     Fields:    Translation:HumansAnimals
    16. Xue J, Suarez JS, Minaai M, Li S, Gaudino G, Pass HI, Carbone M, Yang H. HMGB1 as a therapeutic target in disease. J Cell Physiol. 2021 05; 236(5):3406-3419. PMID: 33107103.
      Citations: 74     Fields:    Translation:HumansAnimalsCells
    17. Xue J, Patergnani S, Giorgi C, Suarez J, Goto K, Bononi A, Tanji M, Novelli F, Pastorino S, Xu R, Caroccia N, Dogan AU, Pass HI, Tognon M, Pinton P, Gaudino G, Mak TW, Carbone M, Yang H. Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy. Proc Natl Acad Sci U S A. 2020 10 13; 117(41):25543-25552. PMID: 32999071.
      Citations: 36     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    18. Pass HI, Alimi M, Carbone M, Yang H, Goparaju CM. Mesothelioma Biomarkers: Discovery in Search of Validation. Thorac Surg Clin. 2020 Nov; 30(4):395-423. PMID: 33012429.
      Citations: 7     Fields:    Translation:Humans
    19. Pass HI, Alimi M, Carbone M, Yang H, Goparaju CM. Mesothelioma Biomarkers: A Review Highlighting Contributions from the Early Detection Research Network. Cancer Epidemiol Biomarkers Prev. 2020 12; 29(12):2524-2540. PMID: 32699075.
      Citations: 13     Fields:    Translation:Humans
    20. Carbone M, Harbour JW, Brugarolas J, Bononi A, Pagano I, Dey A, Krausz T, Pass HI, Yang H, Gaudino G. Biological Mechanisms and Clinical Significance of BAP1 Mutations in Human Cancer. Cancer Discov. 2020 08; 10(8):1103-1120. PMID: 32690542.
      Citations: 78     Fields:    Translation:Humans
    21. Carbone M. Transitional Mesothelioma and Artificial Intelligence: Do We Need One More Subtype? and Do We Need Computers to Identify Them? J Thorac Oncol. 2020 06; 15(6):884-887. PMID: 32471562.
      Citations: 1     Fields:    Translation:Humans
    22. Carbone M, Arron ST, Beutler B, Bononi A, Cavenee W, Cleaver JE, Croce CM, D'Andrea A, Foulkes WD, Gaudino G, Groden JL, Henske EP, Hickson ID, Hwang PM, Kolodner RD, Mak TW, Malkin D, Monnat RJ, Novelli F, Pass HI, Petrini JH, Schmidt LS, Yang H. Tumour predisposition and cancer syndromes as models to study gene-environment interactions. Nat Rev Cancer. 2020 09; 20(9):533-549. PMID: 32472073.
      Citations: 47     Fields:    Translation:HumansAnimals
    23. Napolitano A, Antoine DJ, Pellegrini L, Baumann F, Pagano I, Pastorino S, Goparaju CM, Prokrym K, Canino C, Pass HI, Carbone M, Yang H. Expression of Concern: HMGB1 and Its Hyperacetylated Isoform are Sensitive and Specific Serum Biomarkers to Detect Asbestos Exposure and to Identify Mesothelioma Patients. Clin Cancer Res. 2020 03 15; 26(6):1529. PMID: 32169964.
      Citations: 1     Fields:    
    24. Carbone M, Green JB, Bucci EM, Lednicky JA. Coronaviruses: Facts, Myths, and Hypotheses. J Thorac Oncol. 2020 05; 15(5):675-678. PMID: 32151778.
      Citations: 16     Fields:    Translation:HumansCellsPHPublic Health
    25. Carbone M. This special volume of mesothelioma is dedicated to my friend Adi Gazdar. Transl Lung Cancer Res. 2020 Feb; 9(Suppl 1):S1-S2. PMID: 32206566.
      Citations:    
    26. Carbone M, Gazdar A, Butel JS. SV40 and human mesothelioma. Transl Lung Cancer Res. 2020 Feb; 9(Suppl 1):S47-S59. PMID: 32206570.
      Citations:    
    27. Lee HJ, Pham T, Chang MT, Barnes D, Cai AG, Noubade R, Totpal K, Chen X, Tran C, Hagenbeek T, Wu X, Eastham-Anderson J, Tao J, Lee W, Bastian BC, Carbone M, Webster JD, Dey A. The Tumor Suppressor BAP1 Regulates the Hippo Pathway in Pancreatic Ductal Adenocarcinoma. Cancer Res. 2020 04 15; 80(8):1656-1668. PMID: 31988076.
      Citations: 12     Fields:    Translation:HumansCells
    28. Carbone M, Melino G. Stearoyl CoA Desaturase Regulates Ferroptosis in Ovarian Cancer Offering New Therapeutic Perspectives. Cancer Res. 2019 Oct 15; 79(20):5149-5150. PMID: 31615810.
      Citations: 32     Fields:    Translation:HumansAnimals
    29. Carbone M, Melino G. Lipid metabolism offers anticancer treatment by regulating ferroptosis. Cell Death Differ. 2019 12; 26(12):2516-2519. PMID: 31543514.
      Citations: 4     Fields:    Translation:Humans
    30. Carbone M, Adusumilli PS, Alexander HR, Baas P, Bardelli F, Bononi A, Bueno R, Felley-Bosco E, Galateau-Salle F, Jablons D, Mansfield AS, Minaai M, de Perrot M, Pesavento P, Rusch V, Severson DT, Taioli E, Tsao A, Woodard G, Yang H, Zauderer MG, Pass HI. Mesothelioma: Scientific clues for prevention, diagnosis, and therapy. CA Cancer J Clin. 2019 09; 69(5):402-429. PMID: 31283845.
      Citations: 176     Fields:    Translation:HumansPHPublic Health
    31. Tsao MS, Carbone M, Galateau-Salle F, Moreira AL, Nicholson AG, Roden AC, Adjei AA, Aubry MC, Fennell DA, Gomez D, Harpole D, Hesdorffer M, Hirsch FR, Liu G, Malik S, Nowak A, Peikert T, Salgia R, Szlosarek P, Taioli E, Yang H, Tsao A, Mansfield AS. Pathologic Considerations and Standardization in Mesothelioma Clinical Trials. J Thorac Oncol. 2019 10; 14(10):1704-1717. PMID: 31260832.
      Citations: 2     Fields:    Translation:Humans
    32. Bertino P, Premeaux TA, Fujita T, Haun BK, Marciel MP, Hoffmann FW, Garcia A, Yiang H, Pastorino S, Carbone M, Niki T, Berestecky J, Hoffmann PR, Ndhlovu LC. Targeting the C-terminus of galectin-9 induces mesothelioma apoptosis and M2 macrophage depletion. Oncoimmunology. 2019; 8(8):1601482. PMID: 31413910.
      Citations: 11     Fields:    
    33. Carbone M, Yang H, Gaudino G. Does Chromothripsis Make Mesothelioma an Immunogenic Cancer? J Thorac Oncol. 2019 02; 14(2):157-159. PMID: 30598368.
      Citations: 7     Fields:    Translation:Humans
    34. Affar EB, Carbone M. BAP1 regulates different mechanisms of cell death. Cell Death Dis. 2018 11 19; 9(12):1151. PMID: 30455474.
      Citations: 25     Fields:    Translation:Humans
    35. Pastorino S, Yoshikawa Y, Pass HI, Emi M, Nasu M, Pagano I, Takinishi Y, Yamamoto R, Minaai M, Hashimoto-Tamaoki T, Ohmuraya M, Goto K, Goparaju C, Sarin KY, Tanji M, Bononi A, Napolitano A, Gaudino G, Hesdorffer M, Yang H, Carbone M. A Subset of Mesotheliomas With Improved Survival Occurring in Carriers of BAP1 and Other Germline Mutations. J Clin Oncol. 2018 Oct 30; JCO2018790352. PMID: 30376426.
      Citations: 50     Fields:    
    36. Daou S, Barbour H, Ahmed O, Masclef L, Baril C, Sen Nkwe N, Tchelougou D, Uriarte M, Bonneil E, Ceccarelli D, Mashtalir N, Tanji M, Masson JY, Thibault P, Sicheri F, Yang H, Carbone M, Therrien M, Affar EB. Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1. Nat Commun. 2018 10 22; 9(1):4385. PMID: 30349006.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    37. Carbone M, Amelio I, Affar EB, Brugarolas J, Cannon-Albright LA, Cantley LC, Cavenee WK, Chen Z, Croce CM, Andrea A, Gandara D, Giorgi C, Jia W, Lan Q, Mak TW, Manley JL, Mikoshiba K, Onuchic JN, Pass HI, Pinton P, Prives C, Rothman N, Sebti SM, Turkson J, Wu X, Yang H, Yu H, Melino G. Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine. Cell Death Differ. 2018 11; 25(11):1885-1904. PMID: 30323273.
      Citations: 15     Fields:    Translation:Humans
    38. Tsao AS, Lindwasser OW, Adjei AA, Adusumilli PS, Beyers ML, Blumenthal GM, Bueno R, Burt BM, Carbone M, Dahlberg SE, de Perrot M, Fennell DA, Friedberg J, Gill RR, Gomez DR, Harpole DH, Hassan R, Hesdorffer M, Hirsch FR, Hmeljak J, Kindler HL, Korn EL, Liu G, Mansfield AS, Nowak AK, Pass HI, Peikert T, Rimner A, Robinson BWS, Rosenzweig KE, Rusch VW, Salgia R, Sepesi B, Simone CB, Sridhara R, Szlosarek P, Taioli E, Tsao MS, Yang H, Zauderer MG, Malik SM. Current and Future Management of Malignant Mesothelioma: A Consensus Report from the National Cancer Institute Thoracic Malignancy Steering Committee, International Association for the Study of Lung Cancer, and Mesothelioma Applied Research Foundation. J Thorac Oncol. 2018 11; 13(11):1655-1667. PMID: 30266660.
      Citations: 38     Fields:    Translation:Humans
    39. Mutti L, Peikert T, Robinson BWS, Scherpereel A, Tsao AS, de Perrot M, Woodard GA, Jablons DM, Wiens J, Hirsch FR, Yang H, Carbone M, Thomas A, Hassan R. Scientific Advances and New Frontiers in Mesothelioma Therapeutics. J Thorac Oncol. 2018 09; 13(9):1269-1283. PMID: 29966799.
      Citations: 52     Fields:    Translation:Humans
    40. Carbone M. Just a handful of publications can collect the prize. Nature. 2018 09; 561(7724):464. PMID: 30258141.
      Citations:    Fields:    Translation:Humans
    41. McCambridge AJ, Napolitano A, Mansfield AS, Fennell DA, Sekido Y, Nowak AK, Reungwetwattana T, Mao W, Pass HI, Carbone M, Yang H, Peikert T. Progress in the Management of Malignant Pleural?Mesothelioma in 2017. J Thorac Oncol. 2018 05; 13(5):606-623. PMID: 29524617.
      Citations: 36     Fields:    Translation:Humans
    42. Carbone M, Guo Z, Mao W. Improving the Accuracy of?Mesothelioma Diagnosis in China. J Thorac Oncol. 2017 08; 12(8):e132. PMID: 28748828.
      Citations: 1     Fields:    Translation:Humans
    43. Bononi A, Yang H, Giorgi C, Patergnani S, Pellegrini L, Su M, Xie G, Signorato V, Pastorino S, Morris P, Sakamoto G, Kuchay S, Gaudino G, Pass HI, Napolitano A, Pinton P, Jia W, Carbone M. Germline BAP1 mutations induce a Warburg effect. Cell Death Differ. 2017 10; 24(10):1694-1704. PMID: 28665402.
      Citations: 64     Fields:    Translation:HumansCells
    44. Bononi A, Giorgi C, Patergnani S, Larson D, Verbruggen K, Tanji M, Pellegrini L, Signorato V, Olivetto F, Pastorino S, Nasu M, Napolitano A, Gaudino G, Morris P, Sakamoto G, Ferris LK, Danese A, Raimondi A, Tacchetti C, Kuchay S, Pass HI, Affar EB, Yang H, Pinton P, Carbone M. BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation. Nature. 2017 06 22; 546(7659):549-553. PMID: 28614305.
      Citations: 167     Fields:    Translation:HumansCells
    45. Carbone M, Yang H. Mesothelioma: recent highlights. Ann Transl Med. 2017 Jun; 5(11):238. PMID: 28706906.
      Citations:    
    46. Chen Z, Gaudino G, Pass HI, Carbone M, Yang H. Diagnostic and prognostic biomarkers for malignant mesothelioma: an update. Transl Lung Cancer Res. 2017 Jun; 6(3):259-269. PMID: 28713671.
      Citations:    
    47. Pellegrini L, Xue J, Larson D, Pastorino S, Jube S, Forest KH, Saad-Jube ZS, Napolitano A, Pagano I, Negi VS, Bianchi ME, Morris P, Pass HI, Gaudino G, Carbone M, Yang H. HMGB1 targeting by ethyl pyruvate suppresses malignant phenotype of human mesothelioma. Oncotarget. 2017 Apr 04; 8(14):22649-22661. PMID: 28186988.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    48. Mao W, Zhang X, Guo Z, Gao Z, Pass HI, Yang H, Carbone M. Association of Asbestos Exposure With Malignant Mesothelioma Incidence in Eastern China. JAMA Oncol. 2017 04 01; 3(4):562-564. PMID: 27918607.
      Citations: 17     Fields:    Translation:HumansPHPublic Health
    49. Szymiczek A, Pastorino S, Larson D, Tanji M, Pellegrini L, Xue J, Li S, Giorgi C, Pinton P, Takinishi Y, Pass HI, Furuya H, Gaudino G, Napolitano A, Carbone M, Yang H. FTY720 inhibits mesothelioma growth in vitro and in a syngeneic mouse model. J Transl Med. 2017 03 15; 15(1):58. PMID: 28298211.
      Citations: 15     Fields:    Translation:AnimalsCells
    50. Guo Z, Carbone M, Zhang X, Su D, Sun W, Lou J, Gao Z, Shao D, Chen J, Zhang G, Hu J, Chen K, Wang F, Pass HI, Yu H, Napolitano A, Yang H, Mao W. Improving the Accuracy of Mesothelioma Diagnosis in China. J Thorac Oncol. 2017 04; 12(4):714-723. PMID: 28007630.
      Citations: 23     Fields:    Translation:Humans
    51. Yoshikawa Y, Emi M, Hashimoto-Tamaoki T, Ohmuraya M, Sato A, Tsujimura T, Hasegawa S, Nakano T, Nasu M, Pastorino S, Szymiczek A, Bononi A, Tanji M, Pagano I, Gaudino G, Napolitano A, Goparaju C, Pass HI, Yang H, Carbone M. High-density array-CGH with targeted NGS unmask multiple noncontiguous minute deletions on chromosome 3p21 in mesothelioma. Proc Natl Acad Sci U S A. 2016 11 22; 113(47):13432-13437. PMID: 27834213.
      Citations: 78     Fields:    Translation:HumansCells
    52. Carbone M, Shimizu D, Napolitano A, Tanji M, Pass HI, Yang H, Pastorino S. Positive nuclear BAP1 immunostaining helps differentiate non-small cell lung carcinomas from malignant mesothelioma. Oncotarget. 2016 Sep 13; 7(37):59314-59321. PMID: 27447750.
      Citations: 23     Fields:    Translation:HumansCells
    53. Napolitano A, Carbone M. Malignant Mesothelioma: Time to Translate? Trends Cancer. 2016 09; 2(9):467-474. PMID: 28603777.
      Citations: 7     Fields:    Translation:HumansAnimals
    54. Carbone M, Kanodia S, Chao A, Miller A, Wali A, Weissman D, Adjei A, Baumann F, Boffetta P, Buck B, de Perrot M, Dogan AU, Gavett S, Gualtieri A, Hassan R, Hesdorffer M, Hirsch FR, Larson D, Mao W, Masten S, Pass HI, Peto J, Pira E, Steele I, Tsao A, Woodard GA, Yang H, Malik S. Consensus Report of the 2015 Weinman International Conference on Mesothelioma. J Thorac Oncol. 2016 08; 11(8):1246-1262. PMID: 27453164.
      Citations: 66     Fields:    Translation:HumansPHPublic Health
    55. Zhang L, Shimizu D, Killeen JL, Honda SA, Lu D, Stanoyevitch A, Lin F, Wang B, Monuki ES, Carbone M. Serous carcinomatous component championed by heparin-binding EGF-like growth factor (HB-EGF) predisposing to metastasis and recurrence in stage I uterine malignant mixed mullerian tumor. Hum Pathol. 2016 07; 53:159-67. PMID: 26980026.
      Citations: 1     Fields:    Translation:Humans
    56. Ransohoff KJ, Jaju PD, Jaju PD, Tang JY, Carbone M, Leachman S, Sarin KY. Familial skin cancer syndromes: Increased melanoma risk. J Am Acad Dermatol. 2016 Mar; 74(3):423-34; quiz 435-6. PMID: 26892652.
      Citations: 20     Fields:    Translation:Humans
    57. Pass HI, Goparaju C, Espin-Garcia O, Donington J, Carbone M, Patel D, Chen Z, Feld R, Cho J, Gadgeel S, Wozniak A, Chachoua A, Leighl N, Tsao MS, de Perrot M, Xu W, Liu G. Plasma Biomarker Enrichment of Clinical Prognostic Indices in Malignant Pleural Mesothelioma. J Thorac Oncol. 2016 06; 11(6):900-9. PMID: 26903362.
      Citations: 10     Fields:    Translation:Humans
    58. Napolitano A, Antoine DJ, Pellegrini L, Baumann F, Pagano I, Pastorino S, Goparaju CM, Prokrym K, Canino C, Pass HI, Carbone M, Yang H. HMGB1 and Its Hyperacetylated Isoform are Sensitive and Specific Serum Biomarkers to Detect Asbestos Exposure and to Identify Mesothelioma Patients. Clin Cancer Res. 2016 06 15; 22(12):3087-96. PMID: 26733616.
      Citations: 57     Fields:    Translation:HumansCellsPHPublic Health
    59. Larson D, Powers A, Ambrosi JP, Tanji M, Napolitano A, Flores EG, Baumann F, Pellegrini L, Jennings CJ, Buck BJ, McLaurin BT, Merkler D, Robinson C, Morris P, Dogan M, Dogan AU, Pass HI, Pastorino S, Carbone M, Yang H. Investigating palygorskite's role in the development of mesothelioma in southern Nevada: Insights into fiber-induced carcinogenicity. J Toxicol Environ Health B Crit Rev. 2016; 19(5-6):213-230. PMID: 27705545.
      Citations: 11     Fields:    Translation:AnimalsCells
    60. Baumann F, Carbone M. Environmental risk of mesothelioma in the United States: An emerging concern-epidemiological issues. J Toxicol Environ Health B Crit Rev. 2016; 19(5-6):231-249. PMID: 27705543.
      Citations: 19     Fields:    Translation:HumansPHPublic Health
    61. Carbone M, Flores EG, Emi M, Johnson TA, Tsunoda T, Behner D, Hoffman H, Hesdorffer M, Nasu M, Napolitano A, Powers A, Minaai M, Baumann F, Bryant-Greenwood P, Lauk O, Kirschner MB, Weder W, Opitz I, Pass HI, Gaudino G, Pastorino S, Yang H. Combined Genetic and Genealogic Studies Uncover a Large BAP1 Cancer Syndrome Kindred Tracing Back Nine Generations to a Common Ancestor from the 1700s. PLoS Genet. 2015 Dec; 11(12):e1005633. PMID: 26683624.
      Citations: 45     Fields:    Translation:Humans
    62. Napolitano A, Carbone M. Concerns About Presence of a Wild-Type BAP1 Allele in Absence of Nuclear Protein Expression. JAMA Dermatol. 2015 Nov; 151(11):1265-6. PMID: 26559347.
      Citations:    Fields:    Translation:Humans
    63. Daou S, Hammond-Martel I, Mashtalir N, Barbour H, Gagnon J, Iannantuono NV, Nkwe NS, Motorina A, Pak H, Yu H, Wurtele H, Milot E, Mallette FA, Carbone M, Affar el B. The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer. J Biol Chem. 2015 Nov 27; 290(48):28643-63. PMID: 26416890.
      Citations: 55     Fields:    Translation:HumansCells
    64. Bononi A, Napolitano A, Pass HI, Yang H, Carbone M. Latest developments in our understanding of the pathogenesis of mesothelioma and the design of targeted therapies. Expert Rev Respir Med. 2015 Oct; 9(5):633-54. PMID: 26308799.
      Citations: 26     Fields:    Translation:Humans
    65. Croce A, Allegrina M, Rinaudo C, Gaudino G, Yang H, Carbone M. Numerous Iron-Rich Particles Lie on the Surface of Erionite Fibers from Rome (Oregon, USA) and Karlik (Cappadocia, Turkey). Microsc Microanal. 2015 Oct; 21(5):1341-7. PMID: 26286705.
      Citations: 6     Fields:    
    66. Klebe S, Driml J, Nasu M, Pastorino S, Zangiabadi A, Henderson D, Carbone M. BAP1 hereditary cancer predisposition syndrome: a case report and review of literature. Biomark Res. 2015; 3:14. PMID: 26140217.
      Citations:    
    67. Baumann F, Buck BJ, Metcalf RV, McLaurin BT, Merkler D, Carbone M. Reply to "No Increased Risk for Mesothelioma in Relation to Natural-Occurring Asbestos in Southern Nevada". J Thorac Oncol. 2015 Jul; 10(7):e64-5. PMID: 26134238.
      Citations:    Fields:    Translation:HumansPHPublic Health
    68. Baumann F, Buck BJ, Metcalf RV, McLaurin BT, Merkler DJ, Carbone M. The Presence of Asbestos in the Natural Environment is Likely Related to Mesothelioma in Young Individuals and Women from Southern Nevada. J Thorac Oncol. 2015 May; 10(5):731-737. PMID: 25668121.
      Citations: 42     Fields:    Translation:HumansPHPublic Health
    69. Nasu M, Emi M, Pastorino S, Tanji M, Powers A, Luk H, Baumann F, Zhang YA, Gazdar A, Kanodia S, Tiirikainen M, Flores E, Gaudino G, Becich MJ, Pass HI, Yang H, Carbone M. High Incidence of Somatic BAP1 alterations in sporadic malignant mesothelioma. J Thorac Oncol. 2015 Apr; 10(4):565-76. PMID: 25658628.
      Citations: 130     Fields:    Translation:HumansCells
    70. Carbone M, Gaudino G, Yang H. Recent insights emerging from malignant mesothelioma genome sequencing. J Thorac Oncol. 2015 Mar; 10(3):409-11. PMID: 25695218.
      Citations: 7     Fields:    Translation:Humans
    71. Hoffmann PR, Panigada M, Soprana E, Terry F, Bandar IS, Napolitano A, Rose AH, Hoffmann FW, Ndhlovu LC, Belcaid M, Moise L, De Groot AS, Carbone M, Gaudino G, Matsui T, Siccardi A, Bertino P. Preclinical development of HIvax: Human survivin highly immunogenic vaccines. Hum Vaccin Immunother. 2015; 11(7):1585-95. PMID: 26042612.
      Citations: 10     Fields:    Translation:HumansCellsPHPublic Health
    72. Guo G, Chmielecki J, Goparaju C, Heguy A, Dolgalev I, Carbone M, Seepo S, Meyerson M, Pass HI. Whole-exome sequencing reveals frequent genetic alterations in BAP1, NF2, CDKN2A, and CUL1 in malignant pleural mesothelioma. Cancer Res. 2015 Jan 15; 75(2):264-9. PMID: 25488749.
      Citations: 147     Fields:    Translation:Humans
    73. Comertpay S, Pastorino S, Tanji M, Mezzapelle R, Strianese O, Napolitano A, Baumann F, Weigel T, Friedberg J, Sugarbaker P, Krausz T, Wang E, Powers A, Gaudino G, Kanodia S, Pass HI, Parsons BL, Yang H, Carbone M. Evaluation of clonal origin of malignant mesothelioma. J Transl Med. 2014 Dec 04; 12:301. PMID: 25471750.
      Citations: 40     Fields:    Translation:Humans
    74. Gaudino G, Yang H, Carbone M. HGF/Met Signaling Is a Key Player in Malignant Mesothelioma Carcinogenesis. Biomedicines. 2014 Nov 14; 2(4):327-344. PMID: 28548074.
      Citations:    
    75. Baumann F, Flores E, Napolitano A, Kanodia S, Taioli E, Pass H, Yang H, Carbone M. Mesothelioma patients with germline BAP1 mutations have 7-fold improved long-term survival. Carcinogenesis. 2015 Jan; 36(1):76-81. PMID: 25380601.
      Citations: 98     Fields:    Translation:Humans
    76. Zhang L, Comertpay S, Shimizu D, DeMay RM, Carbone M, Honda SA, Eaves JM. Axillary metaplastic breast carcinoma with ipsilateral pectoral invasive ductal carcinoma: an unusual presentation. Case Rep Oncol Med. 2014; 2014:938509. PMID: 25364575.
      Citations:    
    77. Rose AH, Bertino P, Hoffmann FW, Gaudino G, Carbone M, Hoffmann PR. Increasing dietary selenium elevates reducing capacity and ERK activation associated with accelerated progression of select mesothelioma tumors. Am J Pathol. 2014 Apr; 184(4):1041-1049. PMID: 24492200.
      Citations: 9     Fields:    Translation:AnimalsCells
    78. Qi F, Okimoto G, Jube S, Napolitano A, Pass HI, Laczko R, Demay RM, Khan G, Tiirikainen M, Rinaudo C, Croce A, Yang H, Gaudino G, Carbone M. Continuous exposure to chrysotile asbestos can cause transformation of human mesothelial cells via HMGB1 and TNF-a signaling. Am J Pathol. 2013 Nov; 183(5):1654-66. PMID: 24160326.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    79. Baumann F, Ambrosi JP, Carbone M. Asbestos is not just asbestos: an unrecognised health hazard. Lancet Oncol. 2013 Jun; 14(7):576-8. PMID: 23725699.
      Citations: 72     Fields:    Translation:HumansPHPublic Health
    80. Carbone M, Yang H, Pass HI, Krausz T, Testa JR, Gaudino G. BAP1 and cancer. Nat Rev Cancer. 2013 03; 13(3):153-9. PMID: 23550303.
      Citations: 293     Fields:    Translation:Humans
    81. Bertino P, Panigada M, Soprana E, Bianchi V, Bertilaccio S, Sanvito F, Rose AH, Yang H, Gaudino G, Hoffmann PR, Siccardi A, Carbone M. Fowlpox-based survivin vaccination for malignant mesothelioma therapy. Int J Cancer. 2013 Aug 01; 133(3):612-23. PMID: 23335100.
      Citations: 13     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    82. Pass HI, Levin SM, Harbut MR, Melamed J, Chiriboga L, Donington J, Huflejt M, Carbone M, Chia D, Goodglick L, Goodman GE, Thornquist MD, Liu G, de Perrot M, Tsao MS, Goparaju C. Fibulin-3 as a blood and effusion biomarker for pleural mesothelioma. N Engl J Med. 2012 Oct 11; 367(15):1417-27. PMID: 23050525.
      Citations: 129     Fields:    Translation:HumansPHPublic Health
    83. Ostroff RM, Mehan MR, Stewart A, Ayers D, Brody EN, Williams SA, Levin S, Black B, Harbut M, Carbone M, Goparaju C, Pass HI. Early detection of malignant pleural mesothelioma in asbestos-exposed individuals with a noninvasive proteomics-based surveillance tool. PLoS One. 2012; 7(10):e46091. PMID: 23056237.
      Citations: 62     Fields:    Translation:HumansPHPublic Health
    84. Carbone M, Ferris LK, Baumann F, Napolitano A, Lum CA, Flores EG, Gaudino G, Powers A, Bryant-Greenwood P, Krausz T, Hyjek E, Tate R, Friedberg J, Weigel T, Pass HI, Yang H. BAP1 cancer syndrome: malignant mesothelioma, uveal and cutaneous melanoma, and MBAITs. J Transl Med. 2012 Aug 30; 10:179. PMID: 22935333.
      Citations: 134     Fields:    Translation:Humans
    85. Rivera Z, Ferrone S, Wang X, Jube S, Yang H, Pass HI, Kanodia S, Gaudino G, Carbone M. CSPG4 as a target of antibody-based immunotherapy for malignant mesothelioma. Clin Cancer Res. 2012 Oct 01; 18(19):5352-63. PMID: 22893632.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    86. Jube S, Rivera ZS, Bianchi ME, Powers A, Wang E, Pagano I, Pass HI, Gaudino G, Carbone M, Yang H. Cancer cell secretion of the DAMP protein HMGB1 supports progression in malignant mesothelioma. Cancer Res. 2012 Jul 01; 72(13):3290-301. PMID: 22552293.
      Citations: 130     Fields:    Translation:HumansAnimalsCells
    87. Carbone M, Ly BH, Dodson RF, Pagano I, Morris PT, Dogan UA, Gazdar AF, Pass HI, Yang H. Malignant mesothelioma: facts, myths, and hypotheses. J Cell Physiol. 2012 Jan; 227(1):44-58. PMID: 21412769.
      Citations: 169     Fields:    Translation:Humans
    88. Carbone M, Yang H. Molecular pathways: targeting mechanisms of asbestos and erionite carcinogenesis in mesothelioma. Clin Cancer Res. 2012 Feb 01; 18(3):598-604. PMID: 22065079.
      Citations: 104     Fields:    Translation:Humans
    89. Qi F, Carbone M, Yang H, Gaudino G. Simian virus 40 transformation, malignant mesothelioma and brain tumors. Expert Rev Respir Med. 2011 Oct; 5(5):683-97. PMID: 21955238.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    90. Testa JR, Cheung M, Pei J, Below JE, Tan Y, Sementino E, Cox NJ, Dogan AU, Pass HI, Trusa S, Hesdorffer M, Nasu M, Powers A, Rivera Z, Comertpay S, Tanji M, Gaudino G, Yang H, Carbone M. Germline BAP1 mutations predispose to malignant mesothelioma. Nat Genet. 2011 Aug 28; 43(10):1022-5. PMID: 21874000.
      Citations: 430     Fields:    Translation:HumansPHPublic Health
    91. Carbone M, Baris YI, Bertino P, Brass B, Comertpay S, Dogan AU, Gaudino G, Jube S, Kanodia S, Partridge CR, Pass HI, Rivera ZS, Steele I, Tuncer M, Way S, Yang H, Miller A. Erionite exposure in North Dakota and Turkish villages with mesothelioma. Proc Natl Acad Sci U S A. 2011 Aug 16; 108(33):13618-23. PMID: 21788493.
      Citations: 73     Fields:    Translation:HumansPHPublic Health
    92. Nasu M, Carbone M, Gaudino G, Ly BH, Bertino P, Shimizu D, Morris P, Pass HI, Yang H. Ranpirnase Interferes with NF-?B Pathway and MMP9 Activity, Inhibiting Malignant Mesothelioma Cell Invasiveness and Xenograft Growth. Genes Cancer. 2011 May; 2(5):576-84. PMID: 21901170.
      Citations:    
    93. Altomare DA, Menges CW, Xu J, Pei J, Zhang L, Tadevosyan A, Neumann-Domer E, Liu Z, Carbone M, Chudoba I, Klein-Szanto AJ, Testa JR. Losses of both products of the Cdkn2a/Arf locus contribute to asbestos-induced mesothelioma development and cooperate to accelerate tumorigenesis. PLoS One. 2011 Apr 19; 6(4):e18828. PMID: 21526190.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    94. Shukla A, Hillegass JM, MacPherson MB, Beuschel SL, Vacek PM, Butnor KJ, Pass HI, Carbone M, Testa JR, Heintz NH, Mossman BT. ERK2 is essential for the growth of human epithelioid malignant mesotheliomas. Int J Cancer. 2011 Sep 01; 129(5):1075-86. PMID: 21710492.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    95. Shukla A, Hillegass JM, MacPherson MB, Beuschel SL, Vacek PM, Pass HI, Carbone M, Testa JR, Mossman BT. Blocking of ERK1 and ERK2 sensitizes human mesothelioma cells to doxorubicin. Mol Cancer. 2010 Dec 15; 9:314. PMID: 21159167.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    96. Hillegass JM, Blumen SR, Cheng K, MacPherson MB, Alexeeva V, Lathrop SA, Beuschel SL, Steinbacher JL, Butnor KJ, Ramos-Ni?o ME, Shukla A, James TA, Weiss DJ, Taatjes DJ, Pass HI, Carbone M, Landry CC, Mossman BT. Increased efficacy of doxorubicin delivered in multifunctional microparticles for mesothelioma therapy. Int J Cancer. 2011 Jul 01; 129(1):233-44. PMID: 20830711.
      Citations: 19     Fields:    Translation:HumansAnimals
    97. Flores RM, Riedel E, Donington JS, Alago W, Ihekweazu U, Krug L, Rosenzweig K, Adusumilli PS, Carbone M, Pass HI. Frequency of use and predictors of cancer-directed surgery in the management of malignant pleural mesothelioma in a community-based (Surveillance, Epidemiology, and End Results [SEER]) population. J Thorac Oncol. 2010 Oct; 5(10):1649-54. PMID: 20871264.
      Citations: 32     Fields:    Translation:Humans
    98. Zhang L, Qi F, Gaudino G, Strianese O, Yang H, Morris P, Pass HI, Nerurkar VR, Bocchetta M, Carbone M. Tissue Tropism of SV40 Transformation of Human Cells: Role of the Viral Regulatory Region and of Cellular Oncogenes. Genes Cancer. 2010 Oct; 1(10):1008-20. PMID: 21779427.
      Citations:    
    99. Hillegass JM, Shukla A, Lathrop SA, MacPherson MB, Beuschel SL, Butnor KJ, Testa JR, Pass HI, Carbone M, Steele C, Mossman BT. Inflammation precedes the development of human malignant mesotheliomas in a SCID mouse xenograft model. Ann N Y Acad Sci. 2010 Aug; 1203:7-14. PMID: 20716277.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    100. Yang H, Rivera Z, Jube S, Nasu M, Bertino P, Goparaju C, Franzoso G, Lotze MT, Krausz T, Pass HI, Bianchi ME, Carbone M. Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation. Proc Natl Acad Sci U S A. 2010 Jul 13; 107(28):12611-6. PMID: 20616036.
      Citations: 135     Fields:    Translation:HumansAnimalsCells
    101. Demaria S, Pikarsky E, Karin M, Coussens LM, Chen YC, El-Omar EM, Trinchieri G, Dubinett SM, Mao JT, Szabo E, Krieg A, Weiner GJ, Fox BA, Coukos G, Wang E, Abraham RT, Carbone M, Lotze MT. Cancer and inflammation: promise for biologic therapy. J Immunother. 2010 May; 33(4):335-51. PMID: 20386472.
      Citations: 134     Fields:    Translation:HumansAnimals
    102. Pass HI, Goparaju C, Ivanov S, Donington J, Carbone M, Hoshen M, Cohen D, Chajut A, Rosenwald S, Dan H, Benjamin S, Aharonov R. hsa-miR-29c* is linked to the prognosis of malignant pleural mesothelioma. Cancer Res. 2010 Mar 01; 70(5):1916-24. PMID: 20160038.
      Citations: 56     Fields:    Translation:HumansCells
    103. Carbone M. Feasibility of immunotherapy for lymphangioleiomyomatosis. Am J Pathol. 2009 Dec; 175(6):2252-4. PMID: 19893040.
      Citations: 3     Fields:    Translation:Humans
    104. Shukla A, Bosenberg MW, MacPherson MB, Butnor KJ, Heintz NH, Pass HI, Carbone M, Testa JR, Mossman BT. Activated cAMP response element binding protein is overexpressed in human mesotheliomas and inhibits apoptosis. Am J Pathol. 2009 Nov; 175(5):2197-206. PMID: 19815709.
      Citations: 33     Fields:    Translation:HumansCells
    105. Altomare DA, Menges CW, Pei J, Zhang L, Skele-Stump KL, Carbone M, Kane AB, Testa JR. Activated TNF-alpha/NF-kappaB signaling via down-regulation of Fas-associated factor 1 in asbestos-induced mesotheliomas from Arf knockout mice. Proc Natl Acad Sci U S A. 2009 Mar 03; 106(9):3420-5. PMID: 19223589.
      Citations: 45     Fields:    Translation:AnimalsCells
    106. Ivanov SV, Miller J, Lucito R, Tang C, Ivanova AV, Pei J, Carbone M, Cruz C, Beck A, Webb C, Nonaka D, Testa JR, Pass HI. Genomic events associated with progression of pleural malignant mesothelioma. Int J Cancer. 2009 Feb 01; 124(3):589-99. PMID: 18973227.
      Citations: 34     Fields:    Translation:Humans
    107. Yang H, Nasu M, Strianese O, Rivera Z, Luecke L, Carbone M. The legacy of "miracle mineral": asbestos and cancer. Hawaii Med J. 2009 Jan-Feb; 68(1):18-20. PMID: 19365925.
      Citations: 1     Fields:    Translation:Humans
    108. Pass HI, Carbone M. Current status of screening for malignant pleural mesothelioma. Semin Thorac Cardiovasc Surg. 2009; 21(2):97-104. PMID: 19822280.
      Citations: 22     Fields:    Translation:HumansPHPublic Health
    109. Bertino P, Carbone M, Pass H. Chemotherapy of malignant pleural mesothelioma. Expert Opin Pharmacother. 2009 Jan; 10(1):99-107. PMID: 19236184.
      Citations: 3     Fields:    Translation:Humans
    110. Carbone M, Pannuti A, Zhang L, Testa JR, Bocchetta M. A novel mechanism of late gene silencing drives SV40 transformation of human mesothelial cells. Cancer Res. 2008 Nov 15; 68(22):9488-96. PMID: 19010924.
      Citations: 17     Fields:    Translation:HumansCells
    111. Yang H, Testa JR, Carbone M. Mesothelioma epidemiology, carcinogenesis, and pathogenesis. Curr Treat Options Oncol. 2008 Jun; 9(2-3):147-57. PMID: 18709470.
      Citations: 105     Fields:    Translation:HumansCells
    112. Pass HI, Brewer GJ, Dick R, Carbone M, Merajver S. A phase II trial of tetrathiomolybdate after surgery for malignant mesothelioma: final results. Ann Thorac Surg. 2008 Aug; 86(2):383-9; discussion 390. PMID: 18640301.
      Citations: 31     Fields:    Translation:HumansCTClinical Trials
    113. Rivera Z, Strianese O, Bertino P, Yang H, Pass H, Carbone M. The relationship between simian virus 40 and mesothelioma. Curr Opin Pulm Med. 2008 Jul; 14(4):316-21. PMID: 18520265.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    114. Beck AK, Pass HI, Carbone M, Yang H. Ranpirnase as a potential antitumor ribonuclease treatment for mesothelioma and other malignancies. Future Oncol. 2008 Jun; 4(3):341-9. PMID: 18518759.
      Citations: 12     Fields:    Translation:HumansAnimals
    115. Bocchetta M, Eliasz S, De Marco MA, Rudzinski J, Zhang L, Carbone M. The SV40 large T antigen-p53 complexes bind and activate the insulin-like growth factor-I promoter stimulating cell growth. Cancer Res. 2008 Feb 15; 68(4):1022-9. PMID: 18281476.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    116. Flores RM, Pass HI, Seshan VE, Dycoco J, Zakowski M, Carbone M, Bains MS, Rusch VW. Extrapleural pneumonectomy versus pleurectomy/decortication in the surgical management of malignant pleural mesothelioma: results in 663 patients. J Thorac Cardiovasc Surg. 2008 Mar; 135(3):620-6, 626.e1-3. PMID: 18329481.
      Citations: 176     Fields:    Translation:Humans
    117. Bocchetta M, Carbone M. SV40 Tag/p53 complexes actively promote malignant cell growth of human mesothelial cells. Cell Oncol. 2008; 30(5):455. PMID: 18853526.
      Citations: 1     Fields:    Translation:HumansCells
    118. Pass HI, Wali A, Tang N, Ivanova A, Ivanov S, Harbut M, Carbone M, Allard J. Soluble mesothelin-related peptide level elevation in mesothelioma serum and pleural effusions. Ann Thorac Surg. 2008 Jan; 85(1):265-72; discussion 272. PMID: 18154821.
      Citations: 47     Fields:    Translation:Humans
    119. Ramos-Nino ME, Blumen SR, Sabo-Attwood T, Pass H, Carbone M, Testa JR, Altomare DA, Mossman BT. HGF mediates cell proliferation of human mesothelioma cells through a PI3K/MEK5/Fra-1 pathway. Am J Respir Cell Mol Biol. 2008 Feb; 38(2):209-17. PMID: 17872495.
      Citations: 43     Fields:    Translation:HumansCells
    120. Carbone M, Strianese O, Theos K, Yang H. Mesothelioma. Hawaii Med J. 2007 Feb; 66(2):48-50. PMID: 17393919.
      Citations:    Fields:    Translation:Humans
    121. Carbone M, Emri S, Dogan AU, Steele I, Tuncer M, Pass HI, Baris YI. A mesothelioma epidemic in Cappadocia: scientific developments and unexpected social outcomes. Nat Rev Cancer. 2007 02; 7(2):147-54. PMID: 17251920.
      Citations: 71     Fields:    Translation:HumansPHPublic Health
    122. Kroczynska B, Cutrone R, Bocchetta M, Yang H, Elmishad AG, Vacek P, Ramos-Nino M, Mossman BT, Pass HI, Carbone M. Crocidolite asbestos and SV40 are cocarcinogens in human mesothelial cells and in causing mesothelioma in hamsters. Proc Natl Acad Sci U S A. 2006 Sep 19; 103(38):14128-33. PMID: 16966607.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    123. Kroczynska B, Carbone M. Cross reactivity between many anti-human antibodies for their hamster homologs provide the tools to study the signal transduction pathway activated by asbestos and SV40 in the malignant mesothelioma model. Mol Carcinog. 2006 Jul; 45(7):537-42. PMID: 16649249.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    124. Ramos-Nino ME, Testa JR, Altomare DA, Pass HI, Carbone M, Bocchetta M, Mossman BT. Cellular and molecular parameters of mesothelioma. J Cell Biochem. 2006 Jul 01; 98(4):723-34. PMID: 16795078.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    125. Yang H, Bocchetta M, Kroczynska B, Elmishad AG, Chen Y, Liu Z, Bubici C, Mossman BT, Pass HI, Testa JR, Franzoso G, Carbone M. TNF-alpha inhibits asbestos-induced cytotoxicity via a NF-kappaB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis. Proc Natl Acad Sci U S A. 2006 Jul 05; 103(27):10397-10402. PMID: 16798876.
      Citations: 131     Fields:    Translation:HumansCells
    126. Dogan AU, Baris YI, Dogan M, Emri S, Steele I, Elmishad AG, Carbone M. Genetic predisposition to fiber carcinogenesis causes a mesothelioma epidemic in Turkey. Cancer Res. 2006 May 15; 66(10):5063-8. PMID: 16707428.
      Citations: 45     Fields:    Translation:HumansPHPublic Health
    127. Rdzanek M, Fresco R, Pass HI, Carbone M. Spindle cell tumors of the pleura: differential diagnosis. Semin Diagn Pathol. 2006 Feb; 23(1):44-55. PMID: 17044195.
      Citations: 6     Fields:    Translation:Humans
    128. Carbone M, Bedrossian CW. The pathogenesis of mesothelioma. Semin Diagn Pathol. 2006 Feb; 23(1):56-60. PMID: 17044196.
      Citations: 28     Fields:    Translation:HumansAnimals
    129. Carbone M, Pass HI. Evolving aspects of mesothelioma carcinogenesis: SV40 and genetic predisposition. J Thorac Oncol. 2006 Feb; 1(2):169-71. PMID: 17409848.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    130. Cutrone R, Lednicky J, Dunn G, Rizzo P, Bocchetta M, Chumakov K, Minor P, Carbone M. Some oral poliovirus vaccines were contaminated with infectious SV40 after 1961. Cancer Res. 2005 Nov 15; 65(22):10273-9. PMID: 16288015.
      Citations: 36     Fields:    Translation:AnimalsCellsPHPublic Health
    131. Carbone M, Rdzanek MA, Rudzinski JJ, De Marco MA, Bocchetta M, Ramos Ni?o M, Mossman B, Pass HI. SV40 detection in human tumor specimens. Cancer Res. 2005 Nov 01; 65(21):10120-1. PMID: 16267039.
      Citations: 9     Fields:    Translation:HumansCells
    132. Pass HI, Lott D, Lonardo F, Harbut M, Liu Z, Tang N, Carbone M, Webb C, Wali A. Asbestos exposure, pleural mesothelioma, and serum osteopontin levels. N Engl J Med. 2005 Oct 13; 353(15):1564-73. PMID: 16221779.
      Citations: 119     Fields:    Translation:HumansPHPublic Health
    133. Suzuki M, Toyooka S, Shivapurkar N, Shigematsu H, Miyajima K, Takahashi T, Stastny V, Zern AL, Fujisawa T, Pass HI, Carbone M, Gazdar AF. Aberrant methylation profile of human malignant mesotheliomas and its relationship to SV40 infection. Oncogene. 2005 Feb 10; 24(7):1302-8. PMID: 15592515.
      Citations: 18     Fields:    Translation:HumansCells
    134. Tanvetyanon T, Elmishad AG, Carbone M. Development of malignant mesothelioma during treatment for prolymphocytic leukemia: is asbestos or simian virus 40 a link? Anticancer Res. 2005 Jan-Feb; 25(1B):429-33. PMID: 15816607.
      Citations:    Fields:    Translation:HumansCells
    135. Wali A, Morin PJ, Hough CD, Lonardo F, Seya T, Carbone M, Pass HI. Identification of intelectin overexpression in malignant pleural mesothelioma by serial analysis of gene expression (SAGE). Lung Cancer. 2005 Apr; 48(1):19-29. PMID: 15777968.
      Citations: 21     Fields:    Translation:HumansCells
    136. Carbone M, Pass HI. Multistep and multifactorial carcinogenesis: when does a contributing factor become a carcinogen? Semin Cancer Biol. 2004 Dec; 14(6):399-405. PMID: 15489132.
      Citations: 4     Fields:    Translation:HumansAnimals
    137. Pass HI, Bocchetta M, Carbone M. Evidence of an important role for SV40 in mesothelioma. Thorac Surg Clin. 2004 Nov; 14(4):489-95. PMID: 15559055.
      Citations: 4     Fields:    Translation:HumansCells
    138. Hurtuk MG, Carbone M. A cytokeratin- and calretinin-negative staining sarcomatoid malignant mesothelioma. Anticancer Res. 2004 Sep-Oct; 24(5B):3097-102. PMID: 15510595.
      Citations:    Fields:    Translation:Humans
    139. Bocchetta M, Carbone M. Epidemiology and molecular pathology at crossroads to establish causation: molecular mechanisms of malignant transformation. Oncogene. 2004 Aug 23; 23(38):6484-91. PMID: 15322519.
      Citations: 4     Fields:    Translation:Humans
    140. Carbone M, Klein G, Gruber J, Wong M. Modern criteria to establish human cancer etiology. Cancer Res. 2004 Aug 01; 64(15):5518-24. PMID: 15289363.
      Citations: 27     Fields:    Translation:HumansCells
    141. Pass HI, Vogelzang N, Hahn S, Carbone M. Malignant pleural mesothelioma. Curr Probl Cancer. 2004 May-Jun; 28(3):93-174. PMID: 15197388.
      Citations: 24     Fields:    Translation:Humans
    142. Carbone M, Rdzanek MA. Pathogenesis of malignant mesothelioma. Clin Lung Cancer. 2004 Apr; 5 Suppl 2:S46-50. PMID: 15117424.
      Citations: 6     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    143. Pass HI, Liu Z, Wali A, Bueno R, Land S, Lott D, Siddiq F, Lonardo F, Carbone M, Draghici S. Gene expression profiles predict survival and progression of pleural mesothelioma. Clin Cancer Res. 2004 Feb 01; 10(3):849-59. PMID: 14871960.
      Citations: 47     Fields:    Translation:Humans
    144. Gazdar AF, Carbone M. Molecular pathogenesis of malignant mesothelioma and its relationship to simian virus 40. Clin Lung Cancer. 2003 Nov; 5(3):177-81. PMID: 14667274.
      Citations: 23     Fields:    Translation:HumansCells
    145. Carbone M, Rudzinski J, Bocchetta M. High throughput testing of the SV40 Large T antigen binding to cellular p53 identifies putative drugs for the treatment of SV40-related cancers. Virology. 2003 Oct 25; 315(2):409-14. PMID: 14585344.
      Citations: 4     Fields:    Translation:HumansCells
    146. Carbone M, Burck C, Rdzanek M, Rudzinski J, Cutrone R, Bocchetta M. Different susceptibility of human mesothelial cells to polyomavirus infection and malignant transformation. Cancer Res. 2003 Oct 01; 63(19):6125-9. PMID: 14559789.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    147. Carbone M, Bocchetta M, Cristaudo A, Emri S, Gazdar A, Jasani B, Lednicky J, Miele L, Mutti L, Pass HI, Ramael M, Rizzo P, Testa JR, Weggen S, Yeung A. SV40 and human brain tumors. Int J Cancer. 2003 Aug 10; 106(1):140-2; author reply 143-5. PMID: 12794770.
      Citations: 6     Fields:    Translation:HumansCells
    148. Bocchetta M, Miele L, Pass HI, Carbone M. Notch-1 induction, a novel activity of SV40 required for growth of SV40-transformed human mesothelial cells. Oncogene. 2003 Jan 09; 22(1):81-9. PMID: 12527910.
      Citations: 37     Fields:    Translation:HumansCells
    149. Carbone M, Rizzo P, Powers A, Bocchetta M, Fresco R, Krausz T. Molecular analyses, morphology and immunohistochemistry together differentiate pleural synovial sarcomas from mesotheliomas: clinical implications. Anticancer Res. 2002 Nov-Dec; 22(6B):3443-8. PMID: 12552937.
      Citations: 4     Fields:    Translation:HumansCells
    150. Toyooka S, Carbone M, Toyooka KO, Bocchetta M, Shivapurkar N, Minna JD, Gazdar AF. Progressive aberrant methylation of the RASSF1A gene in simian virus 40 infected human mesothelial cells. Oncogene. 2002 Jun 20; 21(27):4340-4. PMID: 12082623.
      Citations: 18     Fields:    Translation:HumansCells
    151. Foddis R, De Rienzo A, Broccoli D, Bocchetta M, Stekala E, Rizzo P, Tosolini A, Grobelny JV, Jhanwar SC, Pass HI, Testa JR, Carbone M. SV40 infection induces telomerase activity in human mesothelial cells. Oncogene. 2002 Feb 21; 21(9):1434-42. PMID: 11857086.
      Citations: 25     Fields:    Translation:HumansCells
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