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Honghe Wang

TitleDr.
Faculty RankAssistant Professor
InstitutionTuskegee University
DepartmentDepartment of Biology and Center for Cancer Research
Address1200 W Montgomery Rd
Tuskegee AL 36088
Phone3347244986
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    Serving as a faculty at Minority institute and as research mentor for several undergraduate research training programs, I have strong interest in conducting research studies that identify novel gene targets on tumor progression and metastasis in order to develop early diagnostic and targeted therapeutic strategies for cancer patients with metastasis, especially in the African American population. I have strong background and more than fifteen years extensive research experience in the field of molecular biology, oncology, and cell biology/biochemistry etc. I had been a key investigator in the studies of establishing models for anti-cancer drug screening, identification of gene or factors involved in cancer development or cancer metastasis. I also have trained numerous technicians and other laboratory personnel during my research career at NCI under multicultural environment. I have been trained through Health Disparities Research Training Program sponsored by U54 TU/UAB/MSM partnership and systemically explored cancer Health Disparities research in African American population.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ahmed MSU, Lord BD, Adu Addai B, Singhal SK, Gardner K, Salam AB, Ghebremedhin A, White J, Mahmud I, Martini R, Bedi D, Lin H, Jones JD, Karanam B, Dean-Colomb W, Grizzle W, Wang H, Davis M, Yates CC. Immune Profile of Exosomes in African American Breast Cancer Patients Is Mediated by Kaiso/THBS1/CD47 Signaling. Cancers (Basel). 2023 Apr 13; 15(8). PMID: 37190208.
      Citations:    
    2. Angajala A, Raymond H, Muhammad A, Uddin Ahmed MS, Haleema S, Haque M, Wang H, Campbell M, Martini R, Karanam B, Kahn AG, Bedi D, Davis M, Tan M, Dean-Colomb W, Yates C. MicroRNAs within the Basal-like signature of Quadruple Negative Breast Cancer impact overall survival in African Americans. Sci Rep. 2022 12 22; 12(1):22178. PMID: 36550153.
      Citations: 1     Fields:    Translation:Humans
    3. Mori JO, White J, Elhussin I, Duduyemi BM, Karanam B, Yates C, Wang H. Molecular and pathological subtypes related to prostate cancer disparities and disease outcomes in African American and European American patients. Front Oncol. 2022; 12:928357. PMID: 36033462.
      Citations:    
    4. Abisoye-Ogunniyan A, Lin H, Ghebremedhin A, Salam AB, Karanam B, Theodore S, Jones-Trich J, Davis M, Grizzle W, Wang H, Yates C. Transcriptional repressor Kaiso promotes epithelial to mesenchymal transition and metastasis in prostate cancer through direct regulation of miR-200c. Cancer Lett. 2018 09 01; 431:1-10. PMID: 29751044.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    5. Wang H, Liu W, Black S, Turner O, Daniel JM, Dean-Colomb W, He QP, Davis M, Yates C. Kaiso, a transcriptional repressor, promotes cell migration and invasion of prostate cancer cells through regulation of miR-31 expression. Oncotarget. 2016 Feb 02; 7(5):5677-89. PMID: 26734997.
      Citations: 28     Fields:    Translation:HumansCells
    6. Theodore SC, Davis M, Zhao F, Wang H, Chen D, Rhim J, Dean-Colomb W, Turner T, Ji W, Zeng G, Grizzle W, Yates C. MicroRNA profiling of novel African American and Caucasian Prostate Cancer cell lines reveals a reciprocal regulatory relationship of miR-152 and DNA methyltranferase 1. Oncotarget. 2014 Jun 15; 5(11):3512-25. PMID: 25004396.
      Citations: 38     Fields:    Translation:HumansCells
    7. Jones J, Wang H, Karanam B, Theodore S, Dean-Colomb W, Welch DR, Grizzle W, Yates C. Nuclear localization of Kaiso promotes the poorly differentiated phenotype and EMT in infiltrating ductal carcinomas. Clin Exp Metastasis. 2014 Jun; 31(5):497-510. PMID: 24570268.
      Citations: 28     Fields:    Translation:HumansCells
    8. Plisov S, Wang H, Tarasova N, Sharma N, Perantoni AO. Protein/peptide transduction in metanephric explant culture. Methods Mol Biol. 2014; 1092:255-67. PMID: 24318826.
      Citations:    Fields:    Translation:AnimalsCells
    9. Timofeeva OA, Tarasova NI, Zhang X, Chasovskikh S, Cheema AK, Wang H, Brown ML, Dritschilo A. STAT3 suppresses transcription of proapoptotic genes in cancer cells with the involvement of its N-terminal domain. Proc Natl Acad Sci U S A. 2013 Jan 22; 110(4):1267-72. PMID: 23288901.
      Citations: 80     Fields:    Translation:HumansCells
    10. Jones J, Wang H, Zhou J, Hardy S, Turner T, Austin D, He Q, Wells A, Grizzle WE, Yates C. Nuclear Kaiso indicates aggressive prostate cancers and promotes migration and invasiveness of prostate cancer cells. Am J Pathol. 2012 Nov; 181(5):1836-46. PMID: 22974583.
      Citations: 38     Fields:    Translation:HumansCells
    11. Wang H, Jones J, Turner T, He QP, Hardy S, Grizzle WE, Welch DR, Yates C. Clinical and biological significance of KISS1 expression in prostate cancer. Am J Pathol. 2012 Mar; 180(3):1170-1178. PMID: 22226740.
      Citations: 17     Fields:    Translation:Humans
    12. Reams RR, Kalari KR, Wang H, Odedina FT, Soliman KF, Yates C. Detecting gene-gene interactions in prostate disease in African American men. Infect Agent Cancer. 2011 Sep 23; 6 Suppl 2:S1. PMID: 21992608.
      Citations:    
    13. Zhou J, Wang H, Cannon V, Wolcott KM, Song H, Yates C. Side population rather than CD133(+) cells distinguishes enriched tumorigenicity in hTERT-immortalized primary prostate cancer cells. Mol Cancer. 2011 Sep 14; 10:112. PMID: 21917149.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    14. Tanigawa S, Wang H, Yang Y, Sharma N, Tarasova N, Ajima R, Yamaguchi TP, Rodriguez LG, Perantoni AO. Wnt4 induces nephronic tubules in metanephric mesenchyme by a non-canonical mechanism. Dev Biol. 2011 Apr 01; 352(1):58-69. PMID: 21256838.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    15. Hernandez L, Roux KJ, Wong ES, Mounkes LC, Mutalif R, Navasankari R, Rai B, Cool S, Jeong JW, Wang H, Lee HS, Kozlov S, Grunert M, Keeble T, Jones CM, Meta MD, Young SG, Daar IO, Burke B, Perantoni AO, Stewart CL. Functional coupling between the extracellular matrix and nuclear lamina by Wnt signaling in progeria. Dev Cell. 2010 Sep 14; 19(3):413-25. PMID: 20833363.
      Citations: 100     Fields:    Translation:HumansAnimalsCells
    16. Wang H, Yang Y, Sharma N, Tarasova NI, Timofeeva OA, Winkler-Pickett RT, Tanigawa S, Perantoni AO. STAT1 activation regulates proliferation and differentiation of renal progenitors. Cell Signal. 2010 Nov; 22(11):1717-26. PMID: 20624457.
      Citations: 24     Fields:    Translation:HumansCells
    17. Liu W, Zabirnyk O, Wang H, Shiao YH, Nickerson ML, Khalil S, Anderson LM, Perantoni AO, Phang JM. miR-23b targets proline oxidase, a novel tumor suppressor protein in renal cancer. Oncogene. 2010 Sep 02; 29(35):4914-24. PMID: 20562915.
      Citations: 77     Fields:    Translation:HumansCells
    18. Diwan BA, Timofeeva O, Rice JM, Yang Y, Sharma N, Fortini ME, Wang H, Perantoni AO. Inheritance of susceptibility to induction of nephroblastomas in the Noble rat. Differentiation. 2009 Apr; 77(4):424-32. PMID: 19281789.
      Citations: 2     Fields:    Translation:Animals
    19. Yang Y, Kitagaki J, Wang H, Hou DX, Perantoni AO. Targeting the ubiquitin-proteasome system for cancer therapy. Cancer Sci. 2009 Jan; 100(1):24-8. PMID: 19037995.
      Citations: 55     Fields:    Translation:Humans
    20. Wang H, Lillehoj EP, Kim KC. MUC1 tyrosine phosphorylation activates the extracellular signal-regulated kinase. Biochem Biophys Res Commun. 2004 Aug 20; 321(2):448-54. PMID: 15358196.
      Citations: 13     Fields:    Translation:HumansCells
    21. Wang H, Lillehoj EP, Kim KC. Identification of four sites of stimulated tyrosine phosphorylation in the MUC1 cytoplasmic tail. Biochem Biophys Res Commun. 2003 Oct 17; 310(2):341-6. PMID: 14521915.
      Citations: 25     Fields:    Translation:AnimalsCells
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