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Dixie Goss

TitleProfessor of Chemistry
Faculty RankProfessor
InstitutionHunter College, CUNY
Departmentchemistry
AddressRoom 1307 HN, Hunter College, CUNY
695 Park Avenue
New York NY 10065
Phone(212) 772-5383
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    Collapse Research 
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    R56DK020251     (THEIL, ELIZABETH C)Aug 1, 1977 - Jun 30, 2010
    NIH
    Ferritin: Protein/mRNA/DNA in Fe/O Regulation/Metabolism
    Role: Co-Principal Investigator
    R01DK020251     (THEIL, ELIZABETH C)Aug 1, 1977 - Aug 31, 2012
    NIH
    Ferritin: Protein/mRNA/DNA in Fe/O Regulation/Metabolism
    Role: Principal Investigator
    T32GM008399     (GOSS, DIXIE J)Sep 30, 1990 - Jun 30, 1995
    NIH
    MOLECULAR BIOPHYSICS
    Role: Principal Investigator
    R01GM128239     (GOSS, DIXIE J)Feb 20, 2019 - Jan 31, 2023
    NIH
    The mechanism through which mRNA translation enhancer elements drive cap-independent translation
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Whittaker A, Goss DJ. Modeling the Structure and DAP5 Binding Site of a Cap-Independent Translational Enhancer mRNA. bioRxiv. 2023 Jun 07. PMID: 37333283.
      Citations:    
    2. Saha B, Bhardwaj U, Goss DJ. Thermodynamically Favorable Interactions between eIF4E Binding Domain of eIF4GI with Structured 5'-Untranslated Regions Drive Cap-Independent Translation of Selected mRNAs. Biochemistry. 2023 06 06; 62(11):1767-1775. PMID: 37132650.
      Citations:    Fields:    Translation:HumansCells
    3. Powell P, Bhardwaj U, Goss D. Eukaryotic initiation factor 4F promotes a reorientation of eukaryotic initiation factor 3 binding on the 5' and the 3' UTRs of barley yellow dwarf virus mRNA. Nucleic Acids Res. 2022 05 20; 50(9):4988-4999. PMID: 35446425.
      Citations: 2     Fields:    Translation:AnimalsCells
    4. Haizel SA, Bhardwaj U, Gonzalez RL, Mitra S, Goss DJ. 5'-UTR recruitment of the translation initiation factor eIF4GI or DAP5 drives cap-independent translation of a subset of human mRNAs. J Biol Chem. 2020 08 14; 295(33):11693-11706. PMID: 32571876.
      Citations: 23     Fields:    Translation:HumansCells
    5. Bhardwaj U, Powell P, Goss DJ. Eukaryotic initiation factor (eIF) 3 mediates Barley Yellow Dwarf Viral mRNA 3'-5' UTR interactions and 40S ribosomal subunit binding to facilitate cap-independent translation. Nucleic Acids Res. 2019 07 09; 47(12):6225-6235. PMID: 31114905.
      Citations: 10     Fields:    Translation:AnimalsCells
    6. Khan MA, Goss DJ. Poly (A) binding protein enhances the binding affinity of potyvirus VPg to eukaryotic initiation factor eIF4F and activates in vitro translation. Int J Biol Macromol. 2019 Jan; 121:947-955. PMID: 30342940.
      Citations: 6     Fields:    Translation:Cells
    7. Liu Q, Goss DJ. The 3' mRNA I-shaped structure of maize necrotic streak virus binds to eukaryotic translation factors for eIF4F-mediated translation initiation. J Biol Chem. 2018 06 15; 293(24):9486-9495. PMID: 29700118.
      Citations: 4     Fields:    Translation:AnimalsCells
    8. Khan MA, Walden WE, Theil EC, Goss DJ. Thermodynamic and Kinetic Analyses of Iron Response Element (IRE)-mRNA Binding to Iron Regulatory Protein, IRP1. Sci Rep. 2017 08 17; 7(1):8532. PMID: 28819260.
      Citations: 9     Fields:    Translation:AnimalsCells
    9. Khan MA, Goss DJ. Kinetic analyses of phosphorylated and non-phosphorylated eIFiso4E binding to mRNA cap analogues. Int J Biol Macromol. 2018 Jan; 106:387-395. PMID: 28797816.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    10. Zhao P, Liu Q, Miller WA, Goss DJ. Eukaryotic translation initiation factor 4G (eIF4G) coordinates interactions with eIF4A, eIF4B, and eIF4E in binding and translation of the barley yellow dwarf virus 3' cap-independent translation element (BTE). J Biol Chem. 2017 04 07; 292(14):5921-5931. PMID: 28242763.
      Citations: 18     Fields:    Translation:Cells
    11. Domashevskiy AV, Rodriguez DJ, Gunawardana D, Goss DJ. Preparation of Functional, Fluorescently Labeled mRNA Capped with Anthraniloyl-m(7)GpppG. Methods Mol Biol. 2016; 1428:61-75. PMID: 27236792.
      Citations:    Fields:    Translation:Cells
    12. Sharma SD, Kraft JJ, Miller WA, Goss DJ. Recruitment of the 40S ribosome subunit to the 3'-untranslated region (UTR) of a viral mRNA, via the eIF4 complex, facilitates cap-independent translation. J Biol Chem. 2015 May 01; 290(18):11268-81. PMID: 25792742.
      Citations: 22     Fields:    Translation:Cells
    13. Gunawardana D, Domashevskiy AV, Gayler KR, Goss DJ. Efficient preparation and properties of mRNAs containing a fluorescent cap analog: Anthraniloyl-m(7)GpppG. Translation (Austin). 2015 Jan-Jun; 3(1):e988538. PMID: 26779415.
      Citations:    
    14. Domashevskiy AV, Goss DJ. Pokeweed antiviral protein, a ribosome inactivating protein: activity, inhibition and prospects. Toxins (Basel). 2015 Jan 28; 7(2):274-98. PMID: 25635465.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    15. Khan MA, Ma J, Walden WE, Merrick WC, Theil EC, Goss DJ. Rapid kinetics of iron responsive element (IRE) RNA/iron regulatory protein 1 and IRE-RNA/eIF4F complexes respond differently to metal ions. Nucleic Acids Res. 2014 Jun; 42(10):6567-77. PMID: 24728987.
      Citations: 13     Fields:    Translation:AnimalsCells
    16. Banerjee B, Goss DJ. Eukaryotic initiation factor (eIF) 4F binding to barley yellow dwarf virus (BYDV) 3'-untranslated region correlates with translation efficiency. J Biol Chem. 2014 Feb 14; 289(7):4286-94. PMID: 24379412.
      Citations: 8     Fields:    Translation:Cells
    17. Goss DJ, Kleiman FE. Poly(A) binding proteins: are they all created equal? Wiley Interdiscip Rev RNA. 2013 Mar-Apr; 4(2):167-79. PMID: 23424172.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    18. Domashevskiy AV, Miyoshi H, Goss DJ. Inhibition of pokeweed antiviral protein (PAP) by turnip mosaic virus genome-linked protein (VPg). J Biol Chem. 2012 Aug 24; 287(35):29729-38. PMID: 22773840.
      Citations: 5     Fields:    Translation:AnimalsCells
    19. Ma J, Haldar S, Khan MA, Sharma SD, Merrick WC, Theil EC, Goss DJ. Fe2+ binds iron responsive element-RNA, selectively changing protein-binding affinities and regulating mRNA repression and activation. Proc Natl Acad Sci U S A. 2012 May 29; 109(22):8417-22. PMID: 22586079.
      Citations: 26     Fields:    Translation:Cells
    20. Khan MA, Goss DJ. Poly(A)-binding protein increases the binding affinity and kinetic rates of interaction of viral protein linked to genome with translation initiation factors eIFiso4F and eIFiso4F?4B complex. Biochemistry. 2012 Feb 21; 51(7):1388-95. PMID: 22299678.
      Citations: 9     Fields:    Translation:AnimalsCells
    21. Goss DJ, Theil EC. Iron responsive mRNAs: a family of Fe2+ sensitive riboregulators. Acc Chem Res. 2011 Dec 20; 44(12):1320-8. PMID: 22026512.
      Citations: 11     Fields:    Translation:Cells
    22. Yumak H, Khan MA, Goss DJ. Poly(A) tail affects equilibrium and thermodynamic behavior of tobacco etch virus mRNA with translation initiation factors eIF4F, eIF4B and PABP. Biochim Biophys Acta. 2010 Sep; 1799(9):653-8. PMID: 20723624.
      Citations: 8     Fields:    Translation:Cells
    23. Ecevit O, Khan MA, Goss DJ. Kinetic analysis of the interaction of b/HLH/Z transcription factors Myc, Max, and Mad with cognate DNA. Biochemistry. 2010 Mar 30; 49(12):2627-35. PMID: 20170194.
      Citations: 17     Fields:    Translation:Cells
    24. Khan MA, Yumak H, Goss DJ. Kinetic mechanism for the binding of eIF4F and tobacco Etch virus internal ribosome entry site rna: effects of eIF4B and poly(A)-binding protein. J Biol Chem. 2009 Dec 18; 284(51):35461-70. PMID: 19858189.
      Citations: 11     Fields:    Translation:AnimalsCells
    25. Theil EC, Goss DJ. Living with iron (and oxygen): questions and answers about iron homeostasis. Chem Rev. 2009 Oct; 109(10):4568-79. PMID: 19824701.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    26. Khan MA, Walden WE, Goss DJ, Theil EC. Direct Fe2+ sensing by iron-responsive messenger RNA:repressor complexes weakens binding. J Biol Chem. 2009 Oct 30; 284(44):30122-8. PMID: 19720833.
      Citations: 17     Fields:    Translation:AnimalsCells
    27. Cheng S, Sultana S, Goss DJ, Gallie DR. Translation initiation factor 4B homodimerization, RNA binding, and interaction with Poly(A)-binding protein are enhanced by zinc. J Biol Chem. 2008 Dec 26; 283(52):36140-53. PMID: 18977752.
      Citations: 5     Fields:    Translation:AnimalsCells
    28. Baldwin AE, Khan MA, Tumer NE, Goss DJ, Friedland DE. Characterization of pokeweed antiviral protein binding to mRNA cap analogs: competition with nucleotides and enhancement by translation initiation factor iso4G. Biochim Biophys Acta. 2009 Feb; 1789(2):109-16. PMID: 18935985.
      Citations: 4     Fields:    Translation:AnimalsCells
    29. Khan MA, Yumak H, Gallie DR, Goss DJ. Effects of poly(A)-binding protein on the interactions of translation initiation factor eIF4F and eIF4F.4B with internal ribosome entry site (IRES) of tobacco etch virus RNA. Biochim Biophys Acta. 2008 Oct; 1779(10):622-7. PMID: 18692164.
      Citations: 9     Fields:    Translation:AnimalsCells
    30. Khan MA, Miyoshi H, Gallie DR, Goss DJ. Potyvirus genome-linked protein, VPg, directly affects wheat germ in vitro translation: interactions with translation initiation factors eIF4F and eIFiso4F. J Biol Chem. 2008 Jan 18; 283(3):1340-1349. PMID: 18045881.
      Citations: 48     Fields:    Translation:AnimalsCells
    31. Ray S, Yumak H, Domashevskiy A, Khan MA, Gallie DR, Goss DJ. Tobacco etch virus mRNA preferentially binds wheat germ eukaryotic initiation factor (eIF) 4G rather than eIFiso4G. J Biol Chem. 2006 Nov 24; 281(47):35826-34. PMID: 17012235.
      Citations: 15     Fields:    Translation:AnimalsCells
    32. Khan MA, Miyoshi H, Ray S, Natsuaki T, Suehiro N, Goss DJ. Interaction of genome-linked protein (VPg) of turnip mosaic virus with wheat germ translation initiation factors eIFiso4E and eIFiso4F. J Biol Chem. 2006 Sep 22; 281(38):28002-10. PMID: 16880203.
      Citations: 21     Fields:    Translation:AnimalsCells
    33. Banerjee A, Hu J, Goss DJ. Thermodynamics of protein-protein interactions of cMyc, Max, and Mad: effect of polyions on protein dimerization. Biochemistry. 2006 Feb 21; 45(7):2333-8. PMID: 16475822.
      Citations: 13     Fields:    Translation:HumansCells
    34. Hu J, Banerjee A, Goss DJ. Assembly of b/HLH/z proteins c-Myc, Max, and Mad1 with cognate DNA: importance of protein-protein and protein-DNA interactions. Biochemistry. 2005 Sep 06; 44(35):11855-63. PMID: 16128587.
      Citations: 21     Fields:    Translation:Cells
    35. Khan MA, Goss DJ. Translation initiation factor (eIF) 4B affects the rates of binding of the mRNA m7G cap analogue to wheat germ eIFiso4F and eIFiso4F.PABP. Biochemistry. 2005 Mar 22; 44(11):4510-6. PMID: 15766281.
      Citations: 16     Fields:    Translation:AnimalsCells
    36. Khan MA, Goss DJ. Phosphorylation states of translational initiation factors affect mRNA cap binding in wheat. Biochemistry. 2004 Jul 20; 43(28):9092-7. PMID: 15248766.
      Citations: 7     Fields:    Translation:AnimalsCells
    37. Scheper GC, van Kollenburg B, Hu J, Luo Y, Goss DJ, Proud CG. Phosphorylation of eukaryotic initiation factor 4E markedly reduces its affinity for capped mRNA. J Biol Chem. 2002 Feb 01; 277(5):3303-9. PMID: 11723111.
      Citations: 96     Fields:    Translation:HumansCells
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